CO2-capture by engineered mammalian carbonic anhydrases

The favorable characteristics of carbonic anhydrases (CAs) for the efficient and selective capture of CO2 have made them attractive candidates for numerous environmental, industrial, and biomedical applications. The relative instability and the need for cost-efficient, large-scale production of enzymes are the main limitations of these CO2-capture systems. Many studies have been carried out to improve the stability of CAs by either covalent immobilization onto a variety of surfaces or site-directed mutagenesis techniques. Further advances in the field are needed to make CA-based CO2-capture systems real-life tools.