CLEMENTE, FRANCESCA
CLEMENTE, FRANCESCA
Chimica 'Ugo Schiff' - DICUS
3,4,5-Trihydroxypiperidine Based Multivalent Glucocerebrosidase (GCase) Enhancers
2022 Costanza Vanni, Francesca Clemente, Paolo Paoli, Amelia Morrone, Camilla Matassini, Andrea Goti, Francesca Cardona
Amphiphilic Iminosugar Pharmacological Chaperones towards beta-Glucocerebrosidase: Self-Assembly and Biological Activity
2023 Vanni, C; Cardona, F; Clemente, F; Morrone, A; Raudino, M; Ambrosi, M; Lo Nostro, P; Matassini, C
Carbohydrate-based therapeutics for lysosomal storage disorders
2023 Camilla Matassini, Francesca Clemente, Francesca Cardona
GCase Enhancers: A Potential Therapeutic Option for Gaucher Disease and Other Neurological Disorders
2022 Macarena Martínez-Bailén, Francesca Clemente, Camilla Matassini, Francesca Cardona
Glucocerebrosidase (GCase) activity modulation by 2-alkyl trihydroxypiperidines: Inhibition and pharmacological chaperoning
2020 Francesca Clemente, Camilla Matassini, Cristina Faggi, Sara Giachetti, Cosimo Cresti, Amelia Morrone, Paolo Paoli, Andrea Goti, Macarena Martínez-Bailén, Francesca Cardona
Gold nanoparticles decorated with monosaccharides and sulfated ligands as potential modulators of the lysosomal enzyme N-acetylgalactosamine-6-sulfatase (GALNS)
2023 Buco, Francesca; Matassini, Camilla; Vanni, Costanza; Clemente, Francesca; Paoli, Paolo; Carozzini, Cosimo; Beni, Alice; Cardona, Francesca; Goti, Andrea; Moya, Sergio Enrique; Ortore, Maria Grazia; Andreozzi, Patrizia; Morrone, Amelia; Marradi, Marco
Identification of GM1-Ganglioside Secondary Accumulation in Fibroblasts from Neuropathic Gaucher Patients and Effect of a Trivalent Trihydroxypiperidine Iminosugar Compound on Its Storage Reduction
2024 Costanza Ceni, Francesca Clemente, Francesca Mangiavacchi, Camilla Matassini, Rodolfo Tonin, Anna Caciotti, Federica Feo, Domenico Coviello, Amelia Morrone, Francesca Cardona, Martino Calamai
Light-Triggered Control of Glucocerebrosidase Inhibitors: Towards Photoswitchable Pharmacological Chaperones
2023 Francesca Clemente, Maria Giulia Davighi, Camilla Matassini, Francesca Cardona, Andrea Goti, Amelia Morrone, Paolo Paoli, Tomás Tejero, Pedro Merino, Martina Cacciarini
pH-Responsive Trihydroxylated Piperidines Rescue The Glucocerebrosidase Activity in Human Fibroblasts Bearing The Neuronopathic Gaucher-Related L444P/L444P Mutations in GBA1 Gene
2024 Maria Giulia Davighi, Camilla Matassini, Francesca Clemente, Paolo Paoli, Amelia Morrone, Martina Cacciarini, Andrea Goti, and Francesca Cardona
Photoswitchable inhibitors of human β-glucocerebrosidase
2022 Maria Giulia Davighi, Francesca Clemente, Camilla Matassini, Francesca Cardona, Mogens Brøndsted Nielsen, Andrea Goti, Amelia Morrone, Paolo Paoli, Martina Cacciarini
Piperidine Azasugars Bearing Lipophilic Chains: Stereoselective Synthesis and Biological Activity as Inhibitors of Glucocerebrosidase (GCase)
2021 Francesca Clemente, Camilla Matassini, Sara Giachetti, Andrea Goti, Amelia Morrone, Macarena Martínez-Bailén, Sara Orta, Pedro Merino, Francesca Cardona
Reductive Amination Routes in the Synthesis of Piperidine IminoSugars
2020 Francesca Clemente, Camilla Matassini, Francesca Cardona
Stereoselective Synthesis of C‑2 Alkylated Trihydroxypiperidines: Novel Pharmacological Chaperones for Gaucher Disease
2019 Francesca Clemente, Camilla Matassini, Andrea Goti, Amelia Morrone, Paolo Paoli, Francesca Cardona
Stereoselective Synthesis of Heavily Hydroxylated Azepane Iminosugars via Osmium-Catalyzed Tethered Aminohydroxylation
2023 Macarena Martínez-Bailén, Camilla Matassini, Francesca Clemente, Cristina Faggi, Andrea Goti, Francesca Cardona
Synthesis of a New beta-Galactosidase Inhibitor Displaying Pharmacological Chaperone Properties for GM1 Gangliosidosis
2022 Francesca Clemente, Macarena Martínez-Bailén, Camilla Matassini, Amelia Morrone, Silvia Falliano, Anna Caciotti, Paolo Paoli, Andrea Goti, Francesca Cardona
Synthesis of alkylated azasugars and their therapeutic potential against lysosomal storage and neurological disorders: the Gaucher-Parkinson case
2021 Francesca Clemente
Synthesis of “All-Cis” Trihydroxypiperidines from a Carbohydrate-Derived Ketone: Hints for the Design of New -Gal and GCase Inhibitors
2020 Maria Giulia Davighi, Francesca Clemente, Camilla Matassini, Amelia Morrone , Andrea Goti, Macarena Martínez-Bailén, Francesca Cardona
The double reductive amination approach to the synthesis of polyhydroxypiperidines
2019 C. Matassini, F. Clemente, F. Cardona
| Titolo | Data di pubblicazione | Autore(i) | File |
|---|---|---|---|
| 3,4,5-Trihydroxypiperidine Based Multivalent Glucocerebrosidase (GCase) Enhancers | 2022 | Costanza Vanni, Francesca Clemente, Paolo Paoli, Amelia Morrone, Camilla Matassini, Andrea Goti, Francesca Cardona | |
| Amphiphilic Iminosugar Pharmacological Chaperones towards beta-Glucocerebrosidase: Self-Assembly and Biological Activity | 2023 | Vanni, C; Cardona, F; Clemente, F; Morrone, A; Raudino, M; Ambrosi, M; Lo Nostro, P; Matassini, C | |
| Carbohydrate-based therapeutics for lysosomal storage disorders | 2023 | Camilla Matassini, Francesca Clemente, Francesca Cardona | |
| GCase Enhancers: A Potential Therapeutic Option for Gaucher Disease and Other Neurological Disorders | 2022 | Macarena Martínez-Bailén, Francesca Clemente, Camilla Matassini, Francesca Cardona | |
| Glucocerebrosidase (GCase) activity modulation by 2-alkyl trihydroxypiperidines: Inhibition and pharmacological chaperoning | 2020 | Francesca Clemente, Camilla Matassini, Cristina Faggi, Sara Giachetti, Cosimo Cresti, Amelia Morrone, Paolo Paoli, Andrea Goti, Macarena Martínez-Bailén, Francesca Cardona | |
| Gold nanoparticles decorated with monosaccharides and sulfated ligands as potential modulators of the lysosomal enzyme N-acetylgalactosamine-6-sulfatase (GALNS) | 2023 | Buco, Francesca; Matassini, Camilla; Vanni, Costanza; Clemente, Francesca; Paoli, Paolo; Carozzini, Cosimo; Beni, Alice; Cardona, Francesca; Goti, Andrea; Moya, Sergio Enrique; Ortore, Maria Grazia; Andreozzi, Patrizia; Morrone, Amelia; Marradi, Marco | |
| Identification of GM1-Ganglioside Secondary Accumulation in Fibroblasts from Neuropathic Gaucher Patients and Effect of a Trivalent Trihydroxypiperidine Iminosugar Compound on Its Storage Reduction | 2024 | Costanza Ceni, Francesca Clemente, Francesca Mangiavacchi, Camilla Matassini, Rodolfo Tonin, Anna Caciotti, Federica Feo, Domenico Coviello, Amelia Morrone, Francesca Cardona, Martino Calamai | |
| Light-Triggered Control of Glucocerebrosidase Inhibitors: Towards Photoswitchable Pharmacological Chaperones | 2023 | Francesca Clemente, Maria Giulia Davighi, Camilla Matassini, Francesca Cardona, Andrea Goti, Amelia Morrone, Paolo Paoli, Tomás Tejero, Pedro Merino, Martina Cacciarini | |
| pH-Responsive Trihydroxylated Piperidines Rescue The Glucocerebrosidase Activity in Human Fibroblasts Bearing The Neuronopathic Gaucher-Related L444P/L444P Mutations in GBA1 Gene | 2024 | Maria Giulia Davighi, Camilla Matassini, Francesca Clemente, Paolo Paoli, Amelia Morrone, Martina Cacciarini, Andrea Goti, and Francesca Cardona | |
| Photoswitchable inhibitors of human β-glucocerebrosidase | 2022 | Maria Giulia Davighi, Francesca Clemente, Camilla Matassini, Francesca Cardona, Mogens Brøndsted Nielsen, Andrea Goti, Amelia Morrone, Paolo Paoli, Martina Cacciarini | |
| Piperidine Azasugars Bearing Lipophilic Chains: Stereoselective Synthesis and Biological Activity as Inhibitors of Glucocerebrosidase (GCase) | 2021 | Francesca Clemente, Camilla Matassini, Sara Giachetti, Andrea Goti, Amelia Morrone, Macarena Martínez-Bailén, Sara Orta, Pedro Merino, Francesca Cardona | |
| Reductive Amination Routes in the Synthesis of Piperidine IminoSugars | 2020 | Francesca Clemente, Camilla Matassini, Francesca Cardona | |
| Stereoselective Synthesis of C‑2 Alkylated Trihydroxypiperidines: Novel Pharmacological Chaperones for Gaucher Disease | 2019 | Francesca Clemente, Camilla Matassini, Andrea Goti, Amelia Morrone, Paolo Paoli, Francesca Cardona | |
| Stereoselective Synthesis of Heavily Hydroxylated Azepane Iminosugars via Osmium-Catalyzed Tethered Aminohydroxylation | 2023 | Macarena Martínez-Bailén, Camilla Matassini, Francesca Clemente, Cristina Faggi, Andrea Goti, Francesca Cardona | |
| Synthesis of a New beta-Galactosidase Inhibitor Displaying Pharmacological Chaperone Properties for GM1 Gangliosidosis | 2022 | Francesca Clemente, Macarena Martínez-Bailén, Camilla Matassini, Amelia Morrone, Silvia Falliano, Anna Caciotti, Paolo Paoli, Andrea Goti, Francesca Cardona | |
| Synthesis of alkylated azasugars and their therapeutic potential against lysosomal storage and neurological disorders: the Gaucher-Parkinson case | 2021 | Francesca Clemente | |
| Synthesis of “All-Cis” Trihydroxypiperidines from a Carbohydrate-Derived Ketone: Hints for the Design of New -Gal and GCase Inhibitors | 2020 | Maria Giulia Davighi, Francesca Clemente, Camilla Matassini, Amelia Morrone , Andrea Goti, Macarena Martínez-Bailén, Francesca Cardona | |
| The double reductive amination approach to the synthesis of polyhydroxypiperidines | 2019 | C. Matassini, F. Clemente, F. Cardona |