CASCELLA, ROBERTA
 Distribuzione geografica
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Continente #
EU - Europa 5.697
NA - Nord America 5.517
AS - Asia 2.573
SA - Sud America 350
AF - Africa 64
OC - Oceania 47
Continente sconosciuto - Info sul continente non disponibili 2
Totale 14.250
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Nazione #
US - Stati Uniti d'America 5.436
PL - Polonia 2.790
RU - Federazione Russa 1.234
SG - Singapore 745
CN - Cina 621
IT - Italia 514
HK - Hong Kong 344
VN - Vietnam 280
BR - Brasile 270
IE - Irlanda 266
SE - Svezia 220
KR - Corea 205
FI - Finlandia 138
DE - Germania 135
IN - India 130
FR - Francia 101
GB - Regno Unito 89
ID - Indonesia 67
NL - Olanda 53
CA - Canada 52
CH - Svizzera 46
AU - Australia 38
JO - Giordania 35
JP - Giappone 29
ES - Italia 26
AR - Argentina 20
BD - Bangladesh 20
MX - Messico 17
TR - Turchia 17
EC - Ecuador 16
BE - Belgio 15
UA - Ucraina 15
NG - Nigeria 13
CO - Colombia 11
IQ - Iraq 11
CL - Cile 10
ZA - Sudafrica 10
CI - Costa d'Avorio 9
NZ - Nuova Zelanda 9
RO - Romania 9
SK - Slovacchia (Repubblica Slovacca) 9
UZ - Uzbekistan 9
AT - Austria 8
EG - Egitto 8
MA - Marocco 7
SA - Arabia Saudita 7
VE - Venezuela 7
PK - Pakistan 6
PY - Paraguay 6
AZ - Azerbaigian 5
MY - Malesia 5
PE - Perù 5
PH - Filippine 5
BJ - Benin 4
CZ - Repubblica Ceca 4
KE - Kenya 4
TH - Thailandia 4
AE - Emirati Arabi Uniti 3
AL - Albania 3
BO - Bolivia 3
CR - Costa Rica 3
HN - Honduras 3
HU - Ungheria 3
IL - Israele 3
IR - Iran 3
LT - Lituania 3
LU - Lussemburgo 3
TW - Taiwan 3
DK - Danimarca 2
DZ - Algeria 2
ET - Etiopia 2
GA - Gabon 2
GE - Georgia 2
GR - Grecia 2
KG - Kirghizistan 2
KZ - Kazakistan 2
OM - Oman 2
PT - Portogallo 2
RS - Serbia 2
SY - Repubblica araba siriana 2
TT - Trinidad e Tobago 2
UY - Uruguay 2
AM - Armenia 1
AO - Angola 1
BA - Bosnia-Erzegovina 1
BG - Bulgaria 1
CY - Cipro 1
EU - Europa 1
GD - Grenada 1
IS - Islanda 1
JM - Giamaica 1
KW - Kuwait 1
MD - Moldavia 1
MM - Myanmar 1
MN - Mongolia 1
MU - Mauritius 1
NO - Norvegia 1
NP - Nepal 1
PA - Panama 1
PR - Porto Rico 1
Totale 14.248
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Città #
Warsaw 2.788
Santa Clara 1.243
Ashburn 753
Singapore 522
Fairfield 404
Hong Kong 292
Chandler 279
Dublin 265
Seoul 199
Woodbridge 180
Houston 178
San Jose 166
Seattle 162
Cambridge 158
Florence 157
Council Bluffs 156
Wilmington 147
Hefei 144
Beijing 133
Ann Arbor 100
Altamura 91
Lawrence 86
The Dalles 77
Princeton 69
Moscow 66
Boston 64
Los Angeles 64
Ho Chi Minh City 63
Helsinki 58
Dong Ket 57
Lauterbourg 57
Jakarta 52
Hanoi 47
Munich 44
New York 43
Mumbai 42
Bremen 38
Shanghai 38
Buffalo 36
Melbourne 34
Pune 33
San Diego 33
Boardman 32
Kent 31
Dallas 26
Clifton 25
Lappeenranta 24
Rome 24
Turku 24
Bern 22
Milan 22
Phoenix 22
São Paulo 22
Dearborn 21
Barcelona 19
Medford 17
Montreal 16
Tokyo 16
London 15
Paris 15
Abuja 13
Orem 13
Atlanta 12
Basel 12
Bengaluru 12
Redondo Beach 12
Brussels 11
Guangzhou 11
Haiphong 11
Utrecht 11
Chennai 10
Frankfurt am Main 10
Groningen 10
Oakland 10
Rohtak 10
Abidjan 9
Chicago 9
Cologne 9
Jacksonville 9
Redwood City 9
Stockholm 9
Tashkent 9
Toronto 9
Norwalk 8
Rio de Janeiro 8
Veľký Meder 8
Amsterdam 7
Brooklyn 7
Verona 7
Andover 6
Brasília 6
Denver 6
Izmir 6
Naples 6
Zurich 6
Baghdad 5
Charlotte 5
Christchurch 5
Concepción 5
Curitiba 5
Totale 10.357
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Nome #
Oleuropein aglycone induces autophagy via the AMPK/mTOR signalling pathway: A mechanistic insight 355
Binding affinity of amyloid oligomers to cellular membranes is a generic indicator of cellular dysfunction in protein misfolding diseases 321
A natural product inhibits the initiation of α-synuclein aggregation and suppresses its toxicity 320
Structural basis of membrane disruption and cellular toxicity by α-synuclein oligomers 317
Lipid Rafts Mediate Amyloid-induced Calcium Dyshomeostasis and Oxidative Stress in Alzheimer's Disease. 308
Destabilisation, aggregation, toxicity and cytosolic mislocalisation of nucleophosmin regions associated with acute myeloid leukemia 308
Quantification of the Relative Contributions of Loss-of function and Gain-of-function Mechanisms in TAR DNA-binding Protein 43 (TDP-43) Proteinopathies 306
TDP-43 inclusion bodies formed in bacteria are structurally amorphous, non-amyloid and inherently toxic to neuroblastoma cells 306
TDP-43 inclusion bodies formed in bacteria are structurally amorphous, non-amyloid and inherently toxic to neuroblastoma cells 304
TDP-43 inclusion bodies formed in bacteria are structurally amorphous, non-amyloid and inherently toxic to neuroblastoma cells 303
Soluble Oligomers Require a Ganglioside to Trigger Neuronal Calcium Overload 303
Effect of molecular chaperones on aberrant protein oligomers in vitro: super- versus sub-stoichiometric chaperone concentrations 299
Single molecule experiments emphasize GM1 as a key player of the different cytotoxicity of structurally distinct Aβ1-42 oligomers 292
Interaction of toxic and non-toxic HypF-N oligomers with lipid bilayers investigated at high resolution with atomic force microscopy 285
Nucleophosmin contains amyloidogenic regions that are able to form toxic aggregates under physiological conditions 267
Selenium and zinc: Two key players against cadmium-induced neuronal toxicity. 267
α-Synuclein oligomers and fibrils: partners in crime in synucleinopathies 258
S-linolenoyl glutathione intake extends life-span and stress resistance via Sir-2.1 upregulation in Caenorhabditis elegans 256
Glutathione intake promotes longevity through the activation of SIR-2.1 and DAF-16 (FoxO) pathway in C. elegans 255
Molecular links between aberrant protein oligomers and neurodegeneration in Alzheimer’s disease 242
Single particle tracking to study the binding of protein misfolded oligomer to membrane ganglioside GM1 241
Partial Failure of Proteostasis Systems Counteracting TDP-43 Aggregates in Neurodegenerative Diseases 240
The acute myeloid leukemia-associated nucleophosmin 1 gene mutations dictate amyloidogenicity of the C-terminal domain 239
Multistep Inhibition of α‑Synuclein Aggregation and Toxicity in Vitro and in Vivo by Trodusquemine 236
The toxicity of misfolded protein oligomers is independent of their secondary structure 233
Lipid rafts are primary mediators of amyloid oxidative attack on plasma membrane 215
Nanoscopic insights into the surface conformation of neurotoxic amyloid b oligomers 212
Trodusquemine enhances Aβ42 aggregation but suppresses its toxicity by displacing oligomers from cell membranes 211
Allele specific Taqman–based real-time PCR assay to quantify circulating BRAFV600E mutated DNA in plasma of melanoma patients. 205
Sphingosine 1-phosphate attenuates neuronal dysfunction induced by amyloid-β oligomers through endocytic internalization of NMDA receptors 202
Amyloid fibrils act as a reservoir of soluble oligomers, the main culprits in protein deposition diseases 198
Oxidative Stress in Neurodegenerative Diseases: From a Mitochondrial Point of View 195
A comparison of the biochemical modifications caused by toxic and non-toxic protein oligomers in cells 191
Molecular mechanisms used by chaperones to reduce the toxicity of aberrant protein oligomers 189
A quantitative biology approach correlates neuronal toxicity with the largest inclusions of TDP-43 186
An in situ and in vitro investigation of cytoplasmic TDP-43 inclusions reveals the absence of a clear amyloid signature 186
Targeting pathological amyloid aggregates with conformation-sensitive antibodies 185
Neuronal differentiation of human mesenchymal stromal cells increases their resistance to Aβ42 aggregate toxicity. 183
APP and Bace1: Differential effect of cholesterol enrichment on processing and plasma membrane mobility 181
Probing the origin of the toxicity of oligomeric aggregates of α-synuclein with antibodies 176
Novel S-acyl glutathione derivatives prevent amyloid oxidative stress and cholinergic dysfunction in Alzheimer disease models. Free Radic Biol Med. 174
Structure-toxicity relationship in intermediate fibrils from lα-Synuclein condensates 172
Membrane lipid composition and its physicochemical properties define cell vulnerability to aberrant protein oligomers 171
Quantitative Attribution of the Protective Effects of Aminosterols against Protein Aggregates to Their Chemical Structures and Ability to Modulate Biological Membranes 170
Extracellular chaperones prevent Aβ42-induced toxicity in rat brains 169
Quantitative assessment of the degradation of aggregated TDP-43 mediated by the ubiquitin proteasome system and macroautophagy 169
Exploring the release of toxic oligomers from α-synuclein fibrils with antibodies and sted microscopy 168
Plasma Membrane Injury Depends on Bilayer Lipid Composition in Alzheimer’s Disease 167
Transthyretin suppresses the toxicity of oligomers formed by misfolded proteins in vitro 164
Squalamine and its derivatives modulate the aggregation of amyloid-β and α-synuclein and suppress the toxicity of their oligomers 163
Misfolded protein oligomers induce an increase of intracellular Ca2+ causing an escalation of reactive oxidative species 157
Amyloid cytotoxicity depends on membrane lipid composition in Alzheimer's disease 157
Aβ oligomers dysregulate calcium homeostasis by mechanosensitive activation of AMPA and NMDA receptors. 155
Light-responsive nanocomposite sponges for on demand chemical release with high spatial and dosage control 154
Trodusquemine displaces protein misfolded oligomers from cell membranes and abrogates their cytotoxicity through a generic mechanism 152
Putative novel CSF biomarkers of Alzheimer’s disease based on the novel concept of generic protein misfolding and proteotoxicity: the PRAMA cohort 147
Proteostasis Failure in Neurodegenerative Diseases: Focus on Oxidative Stress 147
Calcium dyshomeostasis in Alzheimer’s disease pathogenesis 144
Chaperones suppress protein oligomer toxicity: Insight into the molecular mechanism of action 142
The release of toxic oligomers from α-synuclein fibrils induces dysfunction in neuronal cells 137
Effects of oligomer toxicity, fibril toxicity and fibril spreading in synucleinopathies 134
Transthyretin Inhibits Primary and Secondary Nucleations of Amyloid-β Peptide Aggregation and Reduces the Toxicity of Its Oligomers 131
Chaperones suppress the toxicity of aberrant protein aggregates. Molecular insight into the mechanism of action 129
Exploring the Aβ1-42 fibrillogenesis timeline by atomic force microscopy and surface enhanced Raman spectroscopy 128
Toxicity of Protein Oligomers Is Rationalized by a Function Combining Size and Surface Hydrophobicity 127
A single-domain antibody detects and neutralises toxic Aβ42 oligomers in the Alzheimer's disease CSF 126
Characterization of Pairs of Toxic and Nontoxic Misfolded Protein Oligomers Elucidates the Structural Determinants of Oligomer Toxicity in Protein Misfolding Diseases 125
The Toxicity of Protein Aggregates: New Insights into the Mechanisms 114
An in situ and in vitro investigation of cytoplasmic TDP-43 inclusions reveals the absence of a clear amyloid signature 96
Oxidative Stress and Mitochondrial Damage in Neurodegenerative Diseases: From Molecular Mechanisms to Targeted Therapies 94
Cellular prion protein and calcium ions trigger the neurotoxicity of α-synuclein aggregates 25
Engineering a dimeric single-domain antibody for improved detection and neutralization of amyloid-β oligomers 14
Totale 14.398
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Categoria #
all - tutte 36.538
article - articoli 0
book - libri 0
conference - conferenze 0
curatela - curatele 0
other - altro 0
patent - brevetti 0
selected - selezionate 0
volume - volumi 0
Totale 36.538
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Totale Lug Ago Sett Ott Nov Dic Gen Feb Mar Apr Mag Giu
2020/2021128 0 0 0 0 0 0 0 0 0 0 49 79
2021/2022446 35 43 53 14 13 18 15 31 26 37 42 119
2022/20231.365 106 254 73 130 89 216 161 74 129 42 50 41
2023/2024620 28 61 60 26 35 128 33 125 13 44 32 35
2024/20253.530 101 366 204 523 1.100 464 61 192 154 84 144 137
2025/20263.812 447 541 355 340 468 193 487 210 299 338 134 0
Totale 14.398