CROCETTI, LETIZIA
 Distribuzione geografica
Continente #
EU - Europa 2.445
NA - Nord America 2.032
AS - Asia 286
SA - Sud America 5
AF - Africa 2
Totale 4.770
Nazione #
US - Stati Uniti d'America 2.030
PL - Polonia 1.632
IT - Italia 245
IE - Irlanda 195
SE - Svezia 185
HK - Hong Kong 121
CN - Cina 60
GB - Regno Unito 47
RU - Federazione Russa 46
SG - Singapore 38
VN - Vietnam 30
DE - Germania 25
FI - Finlandia 22
BE - Belgio 21
JO - Giordania 20
ES - Italia 11
IN - India 8
TR - Turchia 7
BR - Brasile 5
NL - Olanda 5
UA - Ucraina 5
FR - Francia 4
CA - Canada 2
EG - Egitto 2
BY - Bielorussia 1
JP - Giappone 1
KR - Corea 1
RO - Romania 1
Totale 4.770
Città #
Warsaw 1.631
Fairfield 323
Dublin 194
Chandler 193
Ashburn 165
Seattle 157
Woodbridge 138
Cambridge 118
Ann Arbor 116
Houston 111
Florence 108
Wilmington 106
Hong Kong 81
Altamura 78
Lawrence 77
Princeton 52
Buffalo 45
Moscow 31
Beijing 27
Boston 26
Singapore 26
Medford 25
Shanghai 23
Dong Ket 22
Boardman 20
Brussels 20
San Diego 19
London 13
Barcelona 11
Jacksonville 11
New York 10
West Jordan 10
Kent 9
Hillsboro 8
Norwalk 7
Phoenix 7
Falls Church 6
Gavirate 6
Izmir 6
Menlo Park 5
Pune 5
Teresópolis 5
Misano Adriatico 4
Andover 3
Chennai 3
Esslingen am Neckar 3
Napoli 3
Scandicci 3
Shenzhen 3
Zhengzhou 3
Carol Stream 2
Castelliri 2
Crawley 2
Los Angeles 2
Milan 2
Paris 2
Prescot 2
Redmond 2
Redwood City 2
Rome 2
Southwark 2
Tappahannock 2
Toronto 2
Trumbull 2
Amsterdam 1
Antwerpen 1
Atlanta 1
Bologna 1
Cairo 1
Campi Bisenzio 1
Cedar Knolls 1
Chicago 1
Chieti 1
Clifton 1
Dallas 1
Dalmine 1
Ergolding 1
Foligno 1
Fuzhou 1
Garden City 1
Hounslow 1
Impruneta 1
Istanbul 1
Lappeenranta 1
Laurel 1
Leawood 1
Minsk 1
Montecatini Terme 1
North Babylon 1
Pescara 1
Prato 1
Reggio Emilia 1
Sacramento 1
Salerno 1
San Mateo 1
San Pietro In Casale 1
Secaucus 1
Seoul 1
Serra 1
Siena 1
Totale 4.140
Nome #
Synthesis, HPLC enantioresolution and X-ray analysis of a new series of C5-methyl pyridazines as N-formyl peptide receptor (FPR) agonists 240
Further studies on 2-arylacetamide pyridazin-3(2H)-ones: design, synthesis and evaluation of 4,6-disubstituted analogs as formyl peptide receptors (FPRs) agonists. 210
Synthesis and pharmacological evaluation of new pyridazin-based thioderivatives as formyl peptide receptor (FPR) agonists 208
Synthesis and evaluation as antitubercular agents of 5-arylethenyl and 5-(hetero)aryl-3-isoxazolecarboxylate 203
Synthesis and evaluation as PDE4 inhibitors of pyrimidine-2,4-dione derivatives 201
α2 Adrenoceptor: a Target for Neuropathic Pain Treatment 196
Design, synthesis and evaluation of N-benzoylindazole derivatives and analogues as inhibitors of human neutrophil elastase 190
Synthesis, enantioresolution and activity profile of chiral 6-methyl-2,4-disubstituted pyridazin-3(2H)-ones as potent N-formyl peptide receptor agonists. 187
Isoxazolo-5(2H)-one: a new scaffold for potent human neutrophil elastase (HNE) inhibitors 177
New pyrazolo[1',5':1,6]pyrimido[4,5-d]pyridazin-4-(3H)-ones fluoroderivatives as human A1 adenosine receptor ligands 169
Synthesis and pharmacological evaluation of novel GABAA subtype receptor ligands with potential anxiolytic-like and anti-hyperlagesic effect 167
Optimization of N-benzoylindazole derivatives as inhibitors of human neutrophil elastase 162
2-Arylacetamido-4-phenylamino-5-substituted pyridazinones as formyl peptide receptors agonists. 139
Synthesis and pharmacological evaluation of indole derivatives as deaza analogues of potent human neutrophil elastase inhibitors 125
Synthesis of five and six-membered N-phenylacetamido substituted heterocycles as formyl peptide receptor agonists 124
Further studies on pyrazolo[1',5':1,6]pyrimido[4,5-d]pyridazin-4(3H)-ones as potent and selective human A1 adenosine receptor antagonists. 122
Synthesis and analytical characterization of new thiazol-2-(3H)-ones as human neutrophil elastase (HNE) inhibitors 115
Synthesis, biological evaluation, and molecular modelling studies of potent human neutrophil elastase (HNE) inhibitors 110
Synthesis of New GABAA Receptor Modulator with Pyrazolo[1,5-a]quinazoline (PQ) Scaffold 110
1H-pyrrolo[2,3-b]pyridine: a new scaffold for human neutrophil elastase (HNE) inhibitors 104
Cinnoline derivatives as human neutrophil elastase inhibitors 103
Synthesis of five and six-membered heterocycles bearing an arylpiperazinylalkyl side chain as orally active antinociceptive agents 97
A thiabendazole sulfonamide shows potent inhibitory activity against mammalian and nematode alpha-carbonic anhydrases. 86
Functionalized pyrazoles and pyrazolo[3,4-d]pyridazinones: synthesis and evaluation of their phosphodiesterase 4 inhibitory activity 86
Further modifications of 1H-pyrrolo[2,3-b]pyridine derivatives as inhibitors of human neutrophil elastase 86
Identification of a new pyrazolo[1,5-a]quinazoline ligand highly affine to γ-aminobutyric type A (GABAA) receptor subtype with anxiolytic-like and antihyperalgesic activity 84
New 3-unsubstituted Isoxazolones as Potent Human Neutrophil Elastase Inhibitors: Synthesis and Molecular Dynamic Simulation 70
New 3,6-disubstituted pyrazolo[1,5-a]quinazolines as ligands to GABAA receptor subtype 64
Pyrazolo[1,5-a]quinazoline scaffold as 5-deaza analogue of pyrazolo[5,1-c][1,2,4]benzotriazine system: synthesis of new derivatives, biological activity on GABAA receptor subtype and molecular dynamic study 64
1,5,6,7-Tetrahydro-4H-indazol-4-ones as human neutrophil elastase (HNE) inhibitors 64
Pyrazolo[1',5':1,6]pyrimido[4,5-d]pyridazin-4(3H)-ones as selective human A1 adenosine receptor ligands 62
GABAA receptor subtype modulators in medicinal chemistry: an updated patent review (2014-present) 60
A patenting perspective on human neutrophil elastase (HNE) inhibitors (2014-2018) and their therapeutic applications 55
Exploration of Nitrogen Heterocycle Scaffolds for the Development of Potent Human Neutrophil Elastase Inhibitors 53
Synthesis, biological evaluation, molecular modeling, and structural analysis of new pyrazole and pyrazolone derivatives as N-formyl peptide receptors agonists 48
'Proximity frequencies' a new parameter to evaluate the profile of GABAAR modulators 47
New insights on the arylpiperazinylalkyl pyridazinone ET1 as potent antinociceptive and anti-inflammatory agent 47
Novel formyl peptide receptor (FPR) agonists with pyridinone and pyrimidindione scaffolds that are potentially useful for the treatment of rheumatoid arthritis 47
Novel Sulfonamide Analogs of Sivelestat as Potent Human Neutrophil Elastase Inhibitors 46
Molecular manipulation of the 1,5,6,7-tetrahydro-4 H -indazol-4-one scaffold to obtain new human neutrophil elastase (HNE) inhibitors 41
Repurposing strategies on pyridazinone-based series by pharmacophore- and structure-driven screening 32
Design and synthesis of the first indole-based blockers of Panx-1 channel 32
New Panx-1 Blockers: Synthesis, Biological Evaluation and Molecular Dynamic Studies 32
An Overview of PDE4 Inhibitors in Clinical Trials: 2010 to Early 2022 31
Editorial: Serine protease inhibitors and their therapeutic applications 28
Design, Synthesis and Pharmacological Evaluation of New Quinoline-Based Panx-1 Channel Blockers 27
X-ray structural study of human neutrophil elastase inhibition with a series of azaindoles, azaindazoles and isoxazolones 24
Synthesis and inverse virtual screening of new bi-cyclic structures towards cancer-relevant cellular targets 23
Pyridinone Derivatives as Interesting Formyl Peptide Receptor (FPR) Agonists for the Treatment of Rheumatoid Arthritis 21
GABAA receptor modulators with a pyrazolo[1,5-a]quinazoline core: synthesis, molecular modelling studies and electrophysiological assay 18
Pyridazinones and Structurally Related Derivatives with Anti-Inflammatory Activity 18
4,5-Dihydro-5-Oxo-Pyrazolo[1,5-a]Thieno[2,3-c]Pyrimidine: A Novel Scaffold Containing Thiophene Ring. Chemical Reactivity and In Silico Studies to Predict the Profile to GABAA Receptor Subtype 15
Ligand Growing Experiments Suggested 4-amino and 4-ureido pyridazin-3(2H)-one as Novel Scaffold for FABP4 Inhibition 14
New quinoline-based PDE4 inhibitors through GSK-256066 fragment-based elaboration 14
Optimization of 4-amino-pyridazin-3(2H)-one as a valid core scaffold for FABP4 inhibitors 12
Protective and Pain-Killer Effects of AMC3, a Novel N-Formyl Peptide Receptors (FPRs) Modulator, in Experimental Models of Rheumatoid Arthritis 11
Pyridazin-3(2H)-one as New FABP4 Inhibitors Suggested by Molecular Growing Experiments 10
PDE4 Inhibitors: Profiling Hits through the Multitude of Structural Classes 6
Ebselen analogues with dual human neutrophil elastase (HNE) inhibitory and antiradical activity 5
Steered Molecular Dynamics Simulations Study on FABP4 Inhibitors 4
Anti-Inflammatory Activity of Pyrazolo[1,5-a]quinazolines 3
Totale 4.949
Categoria #
all - tutte 15.560
article - articoli 0
book - libri 0
conference - conferenze 0
curatela - curatele 0
other - altro 0
patent - brevetti 0
selected - selezionate 0
volume - volumi 0
Totale 15.560


Totale Lug Ago Sett Ott Nov Dic Gen Feb Mar Apr Mag Giu
2019/2020931 87 92 30 66 119 92 91 108 83 71 75 17
2020/2021866 62 71 20 103 45 87 67 52 119 149 38 53
2021/2022411 14 14 35 12 18 29 12 35 20 33 100 89
2022/2023986 96 233 47 71 54 170 126 56 85 5 31 12
2023/2024389 11 41 64 12 22 40 15 106 11 36 22 9
2024/202556 56 0 0 0 0 0 0 0 0 0 0 0
Totale 4.949