MELANI, FABRIZIO
 Distribuzione geografica
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Continente #
NA - Nord America 8.211
EU - Europa 5.483
AS - Asia 4.073
SA - Sud America 521
AF - Africa 118
OC - Oceania 63
Continente sconosciuto - Info sul continente non disponibili 4
Totale 18.473
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Nazione #
US - Stati Uniti d'America 8.085
RU - Federazione Russa 1.775
IT - Italia 1.097
CN - Cina 1.096
SG - Singapore 1.091
HK - Hong Kong 619
SE - Svezia 493
PL - Polonia 467
IE - Irlanda 461
VN - Vietnam 454
BR - Brasile 411
KR - Corea 340
UA - Ucraina 275
DE - Germania 267
GB - Regno Unito 205
FI - Finlandia 164
FR - Francia 162
IN - India 114
BD - Bangladesh 86
CA - Canada 72
JO - Giordania 68
AU - Australia 63
AR - Argentina 47
JP - Giappone 47
ID - Indonesia 28
TR - Turchia 28
ES - Italia 26
NL - Olanda 26
MX - Messico 23
IQ - Iraq 22
ZA - Sudafrica 20
CI - Costa d'Avorio 19
SC - Seychelles 17
BE - Belgio 14
MA - Marocco 14
PK - Pakistan 14
DZ - Algeria 13
EC - Ecuador 12
CO - Colombia 10
UZ - Uzbekistan 10
VE - Venezuela 10
CH - Svizzera 9
PE - Perù 9
NG - Nigeria 8
AT - Austria 7
CL - Cile 7
KE - Kenya 7
LT - Lituania 7
MY - Malesia 7
SA - Arabia Saudita 7
AE - Emirati Arabi Uniti 6
PY - Paraguay 6
CZ - Repubblica Ceca 5
GR - Grecia 5
GT - Guatemala 5
IR - Iran 5
PH - Filippine 5
TN - Tunisia 5
BO - Bolivia 4
JM - Giamaica 4
LV - Lettonia 4
NA - Namibia 4
PT - Portogallo 4
UY - Uruguay 4
EG - Egitto 3
LB - Libano 3
NP - Nepal 3
PA - Panama 3
PR - Porto Rico 3
RO - Romania 3
TT - Trinidad e Tobago 3
TW - Taiwan 3
BB - Barbados 2
CR - Costa Rica 2
CW - ???statistics.table.value.countryCode.CW??? 2
DO - Repubblica Dominicana 2
ET - Etiopia 2
GA - Gabon 2
GE - Georgia 2
HN - Honduras 2
IL - Israele 2
KG - Kirghizistan 2
LK - Sri Lanka 2
NO - Norvegia 2
QA - Qatar 2
SK - Slovacchia (Repubblica Slovacca) 2
SN - Senegal 2
XK - ???statistics.table.value.countryCode.XK??? 2
AG - Antigua e Barbuda 1
AI - Anguilla 1
AZ - Azerbaigian 1
BG - Bulgaria 1
BH - Bahrain 1
BJ - Benin 1
DK - Danimarca 1
GD - Grenada 1
GF - Guiana Francese 1
HR - Croazia 1
KH - Cambogia 1
MM - Myanmar 1
Totale 18.467
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Città #
Santa Clara 1.933
Ashburn 847
Singapore 801
Hong Kong 516
Fairfield 485
Warsaw 467
Dublin 460
Chandler 443
Jacksonville 396
Seoul 335
Hefei 255
Beijing 245
Woodbridge 230
Seattle 220
Milan 213
San Jose 203
Cambridge 201
Wilmington 193
Los Angeles 185
Buffalo 173
Houston 165
Ann Arbor 147
Ho Chi Minh City 131
The Dalles 125
Princeton 119
Florence 110
Lauterbourg 106
Rome 102
Hanoi 85
Council Bluffs 84
Altamura 78
Medford 77
Dallas 72
Lawrence 70
Munich 69
Dong Ket 64
Boardman 63
Shanghai 62
Melbourne 60
Moscow 60
Mumbai 60
New York 60
Boston 55
Kent 54
Tokyo 45
São Paulo 43
Philadelphia 36
San Diego 36
Orem 33
Helsinki 32
Paris 31
Naples 30
Toronto 25
Turku 25
Turin 23
Bologna 21
Da Nang 21
Chicago 20
Frankfurt Am Main 19
Abidjan 18
Clifton 18
Guangzhou 18
Jakarta 18
West Jordan 18
Brooklyn 17
Haiphong 17
Montreal 17
Izmir 16
Norwalk 16
Verona 16
Lappeenranta 15
Redondo Beach 15
Figino 14
Phoenix 14
Brussels 13
Palermo 13
Atlanta 12
Barcelona 12
Chennai 12
London 12
Manchester 12
Rio de Janeiro 12
San Francisco 12
Yubileyny 12
Brasília 10
Genoa 10
Hillsboro 10
Johannesburg 10
Shenzhen 10
Washington 10
Belo Horizonte 9
Frankfurt am Main 9
Mexico City 9
Tashkent 9
Thái Bình 9
Abuja 8
Bengaluru 8
Brescia 8
Catania 8
Nanjing 8
Totale 11.833
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Nome #
Mechanisms for the inhibition of amyloid aggregation by small ligands 322
New fluoro derivatives of the pyrazolo[5,1-c][1,2,4]benzotriazine 5-oxide system: evaluation of fluorine binding properties in the benzodiazepine site on gamma-aminobutyrric acid type A (GABAA) receptor. Design, synthesis, biological evaluation, and molecular modeling investigation. 276
New 3-, 8-disubstituted pyrazolo[5,1-c][1,2,4]benzotriazines useful for studying the interaction with the HBp-3 area (hydrogen bond point area) in the benzodiazepine site on the gamma-aminobutyric acid type A (GABAA) receptor 258
Honey extracts inhibit PTP1B, upregulate insulin receptor expression, and enhance glucose uptake in human HepG2 cells 253
1,3-DIARYLPYRAZOLO[4,5-C]- AND -[5,4-C]QUINOLIN-4-ONES. 4. SYNTHESIS AND SPECIFIC INHIBITION OF BENZODIAZEPINE RECEPTOR BINDING. 250
Combined approach using capillary electrophoresis, NMR and molecular modeling for ambrisentan related substances analysis: Investigation of intermolecular affinities, complexation and separation mechanism 231
13C NMR SPECTRA OF 1,3-OXATHIOLANE, 1,3-OXATHIOLANE-3-OXIDE AND 1,3-OXATHIOLANE-3,3-DIOXIDE DERIVATIVES 220
(S)-(+)-6-Methoxy-α-methyl-2-naphtaleneacetic acid and β-cyclodextrin derivatives: inclusion in aqueous media and solid phase interaction 214
Combination of capillary electrophoresis, molecular modeling and NMR to study the enantioselective complexation of sulpiride with double cyclodextrin systems 213
1H-NMR NOE and molecular modelling to characterize thymol and carvacrol β-cyclodextrin complexes 204
Does Fermentation Really Increase the Phenolic Content in Cereals? A Study on Millet 203
Synthesis, in vivo evaluation, and molecular modeling studies of new pyrazolo[5,1-c][1,2,4]benzotriazine 5-oxide derivatives. Identification of a bifunctional hydrogen bond area related to the inverse-agonism 202
An insight on the alkaloid content of Capparis spinosa L. root by HPLC-DAD-MS, MS/MS and 1H qNMR 196
PYRAZOLO[4,5-C]QUINOLINES. SYNTHESIS AND SPECIFIC INHIBITION OF BENZODIAZEPINE RECEPTOR BINDING. 196
Searching for a reliable orientation of ligands in their binding site: Glide versus FIGO in the case study of PDE4 inhibitorsJ. Med. Chem., , 48(5), 1657-65 196
CARBON-13 NMR STUDY OF NAPROXEN WITH CYCLODEXTRINS IN SOLUTION. 190
Design, Synthesis and Pharmacological Evaluation of New Quinoline-Based Panx-1 Channel Blockers 184
Modeling and Biological Investigations of an Unusual Behavior of Novel Synthesized Acridine- Based Polyamine Ligands in the Binding of Double Helix and G-Quadruplex DNA 184
Design and Solid Phase Synthesis of New DOTA Conjugated (+)-Biotin Dimers Planned to Develop Molecular Weight-Tuned Avidin Oligomers 184
SYNTHESIS OF PYRAZOLO[4,5-D]- AND PYRAZOLO[4,5-C][1]BENZAZEPINE DERIVATIVES. IV. 183
New docking CFF91 parameters specific for cyclodextrin inclusion complexes 183
Synthesis, SAR and in Vitro Evaluation of New Cyclic Arg-Gly-Asp Pseudopentapeptides Containing a s-cis Peptide Bond as Integrin alpha-v-beta3 and alpha-v-beta5 Ligands. 183
GRID-DOCKING STUDY ON LIGANDS ACTING AS INHIBITORS OF THE HUMAN PHOSPHODIESTERASE 4 182
GRIND-derived pharmacophore model for a series of α-tropanyl derivative ligands of the sigma-2 receptor 182
SYNTHESIS AND BINDING STUDY OF PYRAZOLO[4,5-C][1,8]NAPHTHYRIDINES. 181
SYNTHESIS OF 5H-10,11-DIHYDROPYRAZOLO[5,1-C][1,4]BENZODIAZEPINE DERIVATIVES. II. 180
SYNTHESIS, BINDING STUDIES, AND STRUCTURE ACTIVITY RELATIONSHIPS OF 1-ARYL- AND 2-ARYL[1]BENZOPYRANOPYRAZOL-4-ONES, CENTRAL BENZODIAZEPINE RECEPTOR LIGANDS. 180
PYRAZOLO[4,5-C]QUINOLINES. 3. SYNTHESIS, RECEPTOR BINDING, AND 13C-NMR STUDY. 180
Headspace Solid-Phase Microextraction-Gas Chromatography-Mass Spectrometry Quantification of the Volatile Profile of More than 1200 Virgin Olive Oils for Supporting the Panel Test in Their Classification: Comparison of Different Chemometric Approaches 179
Evaluation of the separation mechanism of electrokinetic chromatography with a microemulsion and cyclodextrins using NMR and molecular modeling 178
Exploring the intermolecular interactions acting in solvent-modified MEKC by Molecular Dynamics and NMR: The effect of n-butanol on the separation of diclofenac and its impurities 176
TRICYCLIC HETEROCYCLIC SYSTEMS: PYRAZOLO[5',4':4,5]- AND PYRAZOLO[3',4':4,5]PYRANO[2,3-B]PYRIDINE DERIVATIVES. 175
Benzodiazepine binding activity of some tricyclic heteroarometic systems to define the hydrogen bonding strength of the proton donors of the receptor site. 175
Phase solubility, 1H NMR and molecular modelling studies of bupivacaine hydrochloride complexation with different cyclodextrin derivates 175
SYNTHESIS OF 1,5-DIARYL-3-METHYL-1H-PYRAZOLO[4,5-C]ISOQUINOLINES AND STUDIES OF BINDING TO SPECIFIC PERIPHERAL BENZODIAZEPINE BINDING SITES. 175
SYNTHESIS AND CARBON-13 NMR STUDY OF PYRAZOLO[4,5-C]- AND PYRAZOLO[4,3-C][1]BENZAZEPINES. III. 173
Authentication of the geographical origin of virgin olive oils from the main worldwide producing countries: A new combination of HS-SPME-GC-MS analysis of volatile compounds and chemometrics applied to 1217 samples 173
Stereoselective synthesis of 1,3-disaccharides through Diels-Alder reactions: Part 2: convenient protecting groups for heterodienes and conformational evaluations 172
1-(3-Aminophenyl)-3-methyl[1]benzopyrano[2,3-c]pyrazol-4-one: a new selective A2 adenosine receptor antagonist. 171
. PYRROLNITRIN ANALOGS. XII. SYNTHESIS AND BIOLOGICAL ACTIVITY OF SOME PYRAZOLE CARBOXYLIC ACIDS. 170
STRUCTURE-ACTIVITY RELATIONSHIPS OF 1,2,4-TRIAZOLO[1,5-A]QUINOXALINES AND THEIR 1-DEAZA ANALOGS IMIDAZO[1,2-A]QUINOXALINES AT THE BENZODIAZEPINE RECEPTOR. 168
MOLECULAR MODELING AND NMR NOE EXPERIMENTS: COMPLEMENTARY TOOLS FOR THE INVESTIGATION OF COMPLEX IBUPROXAM-B-CYCLODEXTRIN TOPOLOGY 168
PHASE-SOLUBILITY ANALYSIS AND MOLECULAR MODELING IN THE STUDY OF NAPROXEN-CYCLODEXTRIN INTERACTION. 168
Combination of capillary electrophoresis, Quality by Design, NMR and molecular modeling for impurity profiling: definition of the design space and investigation of intermolecular affinities, complexation and separation mechanisms 168
1H-NMR and molecular modelling techniques for the investigation of the inclusion complex of econazole with a-cyclodextrin in the presence of malic acid 167
'Proximity frequencies' a new parameter to evaluate the profile of GABAAR modulators 167
Composition of discarded Sicilian fruits of Opuntia ficus indica L.: Phenolic content, mineral profile and antioxidant activity in peel, seeds and whole fruit 163
NOVEL ADENOSINE RECEPTOR LIGANDS: 1,3-DISUBSTITUTED[1]BENZOPYRANO[2,3-C]PYRAZOL-4-ONES. SYNTHESIS AND STRUCTURE-ACTIVITY RELATIONSHIPS. 162
Anti-Inflammatory Activity of Pyrazolo[1,5-a]quinazolines 160
TRICYCLIC HETEROAROMATIC SYSTEMS. 1,2,4-TRIAZOLO[1,5-A]QUINOXALINE. 160
DIPYRAZOLO[5,4-B:3',4'-D]PYRIDINES. SYNTHESIS, INHIBITION OF BENZODIAZEPINE RECEPTOR BINDING AND STRUCTURE-ACTIVITY RELATIONSHIPS. 159
Combined use of cyclodextrins and amino acids for the development of cefixime oral solutions for pediatric use 159
TRICYCLIC HETEROAROMATIC SYSTEMS. 1,2,3,4-TETRAHYDROPYRAZOLO[4,3-C][1]BENZAZEPIN-1-ONES AS POTENTIAL ANTITUMOR AGENTS. 157
TRICYCLIC HETEROAROMATIC SYSTEMS: SYNTHESIS, [3H]FLUNITRAZEPAM BRAIN MEMBRANE BINDING INHIBITION, AND STRUCTURE-ACTIVITY RELATIONSHIPS OF 2,3-DIHYDRO-2-ARYL-4-R-[1]BENZOPYRANO[4,3-C]PYRAZOL-3-ONES. 157
Enhancement of Viniferin Production in Vitis vinifera L. cv. Alphonse Lavallée Cell Suspensions by Low-Energy Ultrasound Alone and in Combination with Methyl Jasmonate 157
MOLECULAR DYNAMIC SIMULATION AND DOCKING ENERGY TO FORECAST THE STABILITY OF BCYD-COMPLEX IN WATER SOLUTION. 157
Quantification of volatile fraction by HS-SPME-GC-MS and sensory evaluation of more than 1200 Virgin Olive Oil samples to support Panel Test in Virgin Olive Oil classification 156
HS-SPME-GC-MS and Chemometrics for the Quality Control and Clustering of Monovarietal Extra Virgin Olive Oil: A 3-Year Study on Terpenes and Pentene Dimers of Italian Cultivars 155
Insight into 2-phenylpyrazolo[1,5-a]pyrimidin-3-yl acetamides as Peripheral Benzodiazepine Receptor Ligands: synthesis, biological evaluation and 3D-QSAR investigation. 154
THE CORRECT SYNTHESIS OF 2,3-DIHYDRO-2-ARYL-4-R-[1]BENZOPYRANO[4,3-C]PYRAZOLE-3-ONES. 154
REACTION OF 1-AMINOPHTHALAZINES WITH A-HALOCARBONYL COMPOUNDS: IMIDAZO-2,1-A]PHTHALAZINES AND THEIR BENZODIAZEPINE RECEPTOR ACTIVITIES. 154
TRICYCLIC HETEROAROMATIC SYSTEMS. 5H-1,2,4-TRIAZOLO[5,1-C][1,4]BENZODIAZEPINE. 153
TRICYCLIC HETEROAROMATIC SYSTEMS: [1]BENZOPYRANOPYRAZOL-4-ONES AS BENZODIAZEPINE RECEPTOR LIGANDS. 153
TRICYCLIC HETEROAROMATIC SYSTEMS. 5H-1,2,3-TRIAZOLO[5,1-C][1,4]BENZODIAZEPINE. 153
3D-QSAR, GRID DESCRIPTORS AND CHEMOMETRIC TOOLS IN THE DEVELOPMENT OF SELECTIVE ANTAGONIST OF MUSCARINIC RECEPTOR. 152
New 3,6-disubstituted pyrazolo[1,5-a]quinazolines as ligands to GABAA receptor subtype 152
4-Heteroaryl Substituted Amino-3,5-Dicyanopyridines as New Adenosine Receptor Ligands: Novel Insights on Structure-Activity Relationships and Perspectives 152
Substituted piperazines as nootropic agents: 2- or 3-phenyl derivatives structurally related to the cognition-enhancer DM235 151
HS-SPME-GC-MS Analysis of the Volatile Composition of Italian Honey for Its Characterization and Authentication Using the Genetic Algorithm 148
New isobaric lignans from Refined Olive Oils as quality markers for Virgin Olive Oils 148
PYRROLNITRIN ANALOGS. X. SYNTHESIS AND BIOLOGICAL ACTIVITY OF 1-CHLOROPHENYL-3- OR -5-NITROPHENYLPYRAZOLE-4-CARBOXYLIC ACIDS. 148
PYRROLNITRIN ANALOGS. IX. SYNTHESIS AND BIOLOGICAL ACTIVITY OF 1-TOLYL-3-NITROPHENYL-5-METHYLPYRAZOLE-4-CARBOXYLIC ACIDS AND 1-TOLYL-3-METHYL-5-NITROPHENYLPYRAZOLE-4-CARBOXYLIC ACIDS. FARMACO, EDIZIONE SCIENTIFICA (1984), 39(10), 888-900. 145
Field Interaction and Geometrical Overlap (FIGO): a new Simplex/experimental design-based computational procedure for superposing small ligand molecules. J. Med. Chem., 46(8), 1359-1371 (2003). 145
New Panx-1 Blockers: Synthesis, Biological Evaluation and Molecular Dynamic Studies 144
SYNTHESIS AND BINDING STUDIES OF 1-ARYLPYRAZOLO[4,5-C]- AND 2-ARYLPYRAZOLO[4,3-C]QUINOLIN-4-ONES. 142
FILO (Field Interaction Ligand Optimization): a simplex strategy for searching the optimal ligand interaction field in drug design. 141
Insights into EKC with microemulsions and cyclodextrins by means of NMR and molecular modeling: clemastine case study 141
[1]Benzopyrano-pyrazole-4-ones. Synthesis, binding studies and structure-activity relationships 140
Robust application of a chemometric model based on the relationships between 10 volatile compounds and sensory attributes to support the panel test in virgin olive oil quality classification in olive oil companies 139
Novel 3-aroylpyrazolo[5,1-c][1,2,4] benzotriazines 5-oxides 8-substituted, ligands at GABAA/benzodiazepine receptor complex: synthesis, pharmacological and molecular modelling studies. 138
TRICYCLIC HETEROAROMATIC SYSTEMS. [1]BENZOPYRANOPYRROL-4-ONES AND [1]BENZOPYRANO-1,2,3-TRIAZOL-4-ONES AS BENZODIAZEPINE RECEPTOR LIGANDS. SYNTHESIS AND STRUCTURE-ACTIVITY RELATIONSHIPS. 138
Impurity profiling by capillary electrophoresis: definition of the design space within quality by design approach and investigation of separation mechanism and selectivity 137
Momento dipolare e aree idrofobiche in relazione con l'affinità e l'effetto biologico di ligandi del recettore benzodiazepinico 136
4,5-Dihydro-5-Oxo-Pyrazolo[1,5-a]Thieno[2,3-c]Pyrimidine: A Novel Scaffold Containing Thiophene Ring. Chemical Reactivity and In Silico Studies to Predict the Profile to GABAA Receptor Subtype 135
Usefulness of HS-SPME-GC-MS quantification of volatile compounds for quality control of virgin olive oil 135
3,8-Disubstituted Pyrazolo[1,5-a]quinazoline as GABAA Receptor Modulators: Synthesis, Electrophysiological Assays, and Molecular Modelling Studies 133
[1]Benzopyrano-pyrazole-3-ones. Correct and generalized synthetic metod 133
Molecular modelling assisted design of a TASP mimicking SERPINH1 chaperone function in collagen biosynthesis 133
Pyrazolo[1,5-a]quinazoline scaffold as 5-deaza analogue of pyrazolo[5,1-c][1,2,4]benzotriazine system: synthesis of new derivatives, biological activity on GABAA receptor subtype and molecular dynamic study 130
Effect of cosurfactant on separation selectivity in solvent-modified MEKC: the diclofenac case 129
Evaluation of the separation mechanism in a dual-CD microemulsion system for capillary electrophoresis analysis 129
Enantioseparation and impurity determination of cinacalcet using solvent modified capillary zone electrophoresis and Quality by Design: study of the complexation with cyclodextrins by molecular modeling and NMR 128
Synthesis and biological activity of some 3-(pyrazol-1'-yl)indazole derivatives 127
GABAA receptor modulators with a pyrazolo[1,5-a]quinazoline core: synthesis, molecular modelling studies and electrophysiological assay 126
TRICYCLIC HETEROAROMATIC SYSTEMS 1,2,4-TRIAZOLO[1,5-A]QUINOXALINES: SYNTHESIS AND BENZODIAZEPINE RECEPTOR ACTIVITY. 125
Seasonal and Cultivar-Dependent Phenolic Dynamics in Tuscan Olive Leaves: A Two-Year Study by HPLC-DAD-MS for Food By-Product Valorization 123
PHASE-SOLUBILITY ANAIYSIS AND MOLECULAR MODELLING IN THE STUDY OF INTERACTION OF NAPROXEN WITH HYDROXYETHYL-ß-CYCIODEXTRINS 120
New quinoline-based PDE4 inhibitors through GSK-256066 fragment-based elaboration 119
Synthesis of 3-Carboxy-6-sulfamoylquinolones and Mefloquine-Based Compounds as Panx1 Blockers: Molecular Docking, Electrophysiological and Cell Culture Studies 116
Tricyclic heteroaromatic systems. Synthesis and adenosine receptor binding evaluation of some pyrazolo-quinoline and [1]benzopyrano-pyrazole derivatives 113
Totale 16.622
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Categoria #
all - tutte 49.195
article - articoli 0
book - libri 0
conference - conferenze 0
curatela - curatele 0
other - altro 0
patent - brevetti 0
selected - selezionate 0
volume - volumi 0
Totale 49.195
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Totale Lug Ago Sett Ott Nov Dic Gen Feb Mar Apr Mag Giu
2021/2022669 40 80 39 31 14 23 19 51 19 23 135 195
2022/20231.838 163 271 70 124 177 330 278 123 225 4 50 23
2023/2024793 35 75 117 34 40 115 25 224 15 33 48 32
2024/20255.145 184 497 285 743 1.609 735 70 249 240 114 207 212
2025/20266.254 671 916 718 571 624 221 597 299 368 305 185 779
2026/2027119 119 0 0 0 0 0 0 0 0 0 0 0
Totale 18.619