GIOVANNONI, MARIA PAOLA
 Distribuzione geografica
Continente #
NA - Nord America 9.009
EU - Europa 6.869
AS - Asia 4.218
SA - Sud America 462
AF - Africa 99
OC - Oceania 61
Continente sconosciuto - Info sul continente non disponibili 4
Totale 20.722
Nazione #
US - Stati Uniti d'America 8.919
PL - Polonia 2.161
RU - Federazione Russa 1.781
SG - Singapore 1.161
CN - Cina 1.077
IT - Italia 1.055
HK - Hong Kong 778
VN - Vietnam 408
SE - Svezia 400
IE - Irlanda 398
BR - Brasile 369
KR - Corea 351
DE - Germania 229
GB - Regno Unito 198
UA - Ucraina 191
FI - Finlandia 170
FR - Francia 157
IN - India 118
AU - Australia 61
BD - Bangladesh 57
ID - Indonesia 53
CA - Canada 50
JO - Giordania 43
NL - Olanda 36
JP - Giappone 33
TR - Turchia 27
BE - Belgio 24
AR - Argentina 23
CI - Costa d'Avorio 22
ES - Italia 22
MX - Messico 22
IQ - Iraq 19
ZA - Sudafrica 17
EC - Ecuador 16
CO - Colombia 15
NG - Nigeria 12
CH - Svizzera 11
UZ - Uzbekistan 11
VE - Venezuela 11
PK - Pakistan 10
EG - Egitto 9
PY - Paraguay 8
SC - Seychelles 8
CL - Cile 7
KZ - Kazakistan 7
SA - Arabia Saudita 7
DZ - Algeria 6
KE - Kenya 6
PE - Perù 6
PH - Filippine 6
BO - Bolivia 5
IR - Iran 5
LV - Lettonia 5
TN - Tunisia 5
AE - Emirati Arabi Uniti 4
AT - Austria 4
LA - Repubblica Popolare Democratica del Laos 4
MA - Marocco 4
MY - Malesia 4
AL - Albania 3
LB - Libano 3
LK - Sri Lanka 3
NO - Norvegia 3
NP - Nepal 3
OM - Oman 3
PA - Panama 3
PS - Palestinian Territory 3
RO - Romania 3
SV - El Salvador 3
TT - Trinidad e Tobago 3
TW - Taiwan 3
XK - ???statistics.table.value.countryCode.XK??? 3
AZ - Azerbaigian 2
BJ - Benin 2
BY - Bielorussia 2
CZ - Repubblica Ceca 2
DK - Danimarca 2
ET - Etiopia 2
GE - Georgia 2
JM - Giamaica 2
NI - Nicaragua 2
QA - Qatar 2
RS - Serbia 2
SN - Senegal 2
SY - Repubblica araba siriana 2
TH - Thailandia 2
UY - Uruguay 2
AM - Armenia 1
BB - Barbados 1
BG - Bulgaria 1
BH - Bahrain 1
EE - Estonia 1
EU - Europa 1
GD - Grenada 1
GR - Grecia 1
GT - Guatemala 1
HN - Honduras 1
HR - Croazia 1
HU - Ungheria 1
IL - Israele 1
Totale 20.708
Città #
Warsaw 2.157
Santa Clara 1.976
Ashburn 985
Singapore 810
Hong Kong 672
Fairfield 648
San Jose 498
Chandler 455
Dublin 396
Seoul 344
Seattle 320
Jacksonville 277
Woodbridge 262
Cambridge 258
Hefei 257
Buffalo 253
Houston 229
Beijing 222
Wilmington 195
Milan 187
Council Bluffs 160
Los Angeles 160
Ann Arbor 155
Florence 150
Ho Chi Minh City 132
Princeton 108
Altamura 106
Lawrence 101
Lauterbourg 98
The Dalles 92
Rome 90
Dallas 80
Hanoi 79
Moscow 71
Mumbai 70
Boardman 69
Munich 63
Boston 62
Medford 61
Melbourne 58
Helsinki 55
Shanghai 55
New York 49
Jakarta 46
San Diego 43
Kent 37
Dong Ket 33
Paris 33
London 30
Tokyo 30
Bologna 26
São Paulo 26
West Jordan 25
Brussels 23
Abidjan 22
Turku 22
Chicago 21
Orem 21
Philadelphia 21
Phoenix 21
Da Nang 20
Naples 20
Figino 19
Turin 19
Lappeenranta 18
Clifton 16
Frankfurt am Main 16
Guangzhou 16
Izmir 16
Norwalk 16
Palermo 16
Redondo Beach 16
Toronto 16
Hillsboro 15
Haiphong 14
Baghdad 13
Barcelona 13
Brooklyn 13
Curitiba 13
Frankfurt Am Main 13
Verona 13
Yubileyny 13
Bengaluru 12
Amsterdam 11
Abuja 10
Austin 10
Belo Horizonte 10
Genoa 10
Guayaquil 10
Manchester 10
Tashkent 10
Tianjin 10
Groningen 9
Johannesburg 9
Shenzhen 9
Chennai 8
Dhaka 8
Falls Church 8
Miano 8
Rio de Janeiro 8
Totale 14.519
Nome #
[(3-chlorophenyl)piperazinylpropyl]pyridazinones and analogues as potent antinociceptive agents 438
Isoxazolo-5(2H)-one: a new scaffold for potent human neutrophil elastase (HNE) inhibitors 348
Synthesis, HPLC enantioresolution and X-ray analysis of a new series of C5-methyl pyridazines as N-formyl peptide receptor (FPR) agonists 344
Optimization of N-benzoylindazole derivatives as inhibitors of human neutrophil elastase 323
Synthesis and analytical characterization of new thiazol-2-(3H)-ones as human neutrophil elastase (HNE) inhibitors 323
Synthesis and evaluation as PDE4 inhibitors of pyrimidine-2,4-dione derivatives 308
Presynaptic Cholinergic Modulators as Potent Cognition Enhancers and Analgesic Drugs. 2. 2-Phenoxy-, 2-(phenylthio)- and 2-(phenylamino)alkanoic Acid Esters 301
Further studies on 2-arylacetamide pyridazin-3(2H)-ones: design, synthesis and evaluation of 4,6-disubstituted analogs as formyl peptide receptors (FPRs) agonists. 299
Identification of a new pyrazolo[1,5-a]quinazoline ligand highly affine to γ-aminobutyric type A (GABAA) receptor subtype with anxiolytic-like and antihyperalgesic activity 299
Design, synthesis and evaluation of N-benzoylindazole derivatives and analogues as inhibitors of human neutrophil elastase 298
Synthesis and evaluation as antitubercular agents of 5-arylethenyl and 5-(hetero)aryl-3-isoxazolecarboxylate 294
Synthesis and pharmacological evaluation of new pyridazin-based thioderivatives as formyl peptide receptor (FPR) agonists 281
α2 Adrenoceptor: a Target for Neuropathic Pain Treatment 278
2-Arylacetamido-4-phenylamino-5-substituted pyridazinones as formyl peptide receptors agonists. 275
Development of small molecule non-peptide formyl peptide receptor (FPR) ligands and molecular modeling of their recognition 270
Synthesis, enantioresolution and activity profile of chiral 6-methyl-2,4-disubstituted pyridazin-3(2H)-ones as potent N-formyl peptide receptor agonists. 264
New pyrazolo[1',5':1,6]pyrimido[4,5-d]pyridazin-4-(3H)-ones fluoroderivatives as human A1 adenosine receptor ligands 262
Synthesis of five and six-membered heterocycles bearing an arylpiperazinylalkyl side chain as orally active antinociceptive agents 255
Synthesis and pharmacological evaluation of indole derivatives as deaza analogues of potent human neutrophil elastase inhibitors 244
Synthesis and pharmacological evaluation of novel GABAA subtype receptor ligands with potential anxiolytic-like and anti-hyperlagesic effect 240
An Overview of PDE4 Inhibitors in Clinical Trials: 2010 to Early 2022 226
Synthesis, biological evaluation, and molecular modelling studies of potent human neutrophil elastase (HNE) inhibitors 223
A combined crystallographic and computational study on dexketoprofen trometamol dihydrate salt 222
Synthesis of five and six-membered N-phenylacetamido substituted heterocycles as formyl peptide receptor agonists 222
Synthesis of New GABAA Receptor Modulator with Pyrazolo[1,5-a]quinazoline (PQ) Scaffold 221
ANTINOCICEPTIVE ACTIVITY OF A 3(2H)-PYRIDAZINONE DERIVATE IN MICE 214
4-SUBSTITUTED-5-ACETYL-2-METHYL-6-PHENYL-3(2H)PYRIDAZINONES AS PGE2 AND IL-1 RELEASE INHIBITORS FROM MOUSE ADHERENT MACROPHAGES 212
Further studies on pyrazolo[1',5':1,6]pyrimido[4,5-d]pyridazin-4(3H)-ones as potent and selective human A1 adenosine receptor antagonists. 212
Synthesis of pyrrolo[2,3-d]pyridazinones as potent, subtype selective PDE4 inhibitors 211
CHIRAL RESOLUTION AND ABSOLUTE CONFIGURATION OF THE ENANTIOMERS OF 5-ACETYL-2-METHYL-4-METHYLSULFINYL-6-PHENYL-3(2H)-PYRIDAZINONE AND EVALUATION OF THEIR PLATELET AGGREGATION INHIBITORY ACTIVITY 210
Effects of the neutrophil elastase inhibitor EL-17 in rat adjuvant-induced arthritis. 209
1H-pyrrolo[2,3-b]pyridine: a new scaffold for human neutrophil elastase (HNE) inhibitors 208
5-ACETYL-2-METHYL-4-NITRO-6-PHENYL-3(2H)-PYRIDAZINONE:VERSATILE PRECURSOR TO HETERO-CONDENSED PYRIDAZINONES 206
Further modifications of 1H-pyrrolo[2,3-b]pyridine derivatives as inhibitors of human neutrophil elastase 202
Exploration of Nitrogen Heterocycle Scaffolds for the Development of Potent Human Neutrophil Elastase Inhibitors 202
4-Amino-5-substituted-3(2H)-pyridazinones as orally active antinociceptive agents: synthesis and studies on the mechanism of action 201
Cinnoline derivatives as human neutrophil elastase inhibitors 195
1,5,6,7-Tetrahydro-4H-indazol-4-ones as human neutrophil elastase (HNE) inhibitors 192
Arylpiperazinylalkylpyridazinones and analogues as potent and orally active antinociceptive agents: synthesis and studies on mechanism of action 190
Design, Synthesis and Pharmacological Evaluation of New Quinoline-Based Panx-1 Channel Blockers 184
4,5-FUNCTIONALIZED 6-PHENYL-3(2H)-PIRIDAZINONES:SYNTHESIS AND EVALUATION OF ANTINOCICEPTIVE ACTIVITY 184
Functionalized pyrazoles and pyrazolo[3,4-d]pyridazinones: synthesis and evaluation of their phosphodiesterase 4 inhibitory activity 184
6-Methyl-2,4-disubstituted pyridazin-3(2H)-ones: a novel class of small-molecule agonists for formyl peptide receptors. 183
ISOXAZOLO[3,4-D]PYRIDAZIN-7-(6H)-ONE AS A POTENTIAL SUBSTRATE FOR NEW ALDOSE REDUCTASE INHIBITORS 180
4-AMINO-3(2H)-PYRIDAZINONES BEARING ARYLPIPERAZINYLALKYL GROUPS AND RELATED COMPOUNDS: SYNTHESIS AND ANTINOCICEPTIVE ACTIVITY 178
SELECTIVE ACAT INHIBITORS AS PROMISING ANTIHYPERLIPIDEMIC, ANTIATHEROSCLEROTIC AND ANTI-ALZHEIMER DRUGS 177
ISOXAZOLO[3,4-D]PYRIDAZINONES AND ANALOGUES AS LEISHMANIA MEXICANA PDE INHIBITORS 175
Protective and Pain-Killer Effects of AMC3, a Novel N-Formyl Peptide Receptors (FPRs) Modulator, in Experimental Models of Rheumatoid Arthritis 172
NOVEL 3-ARYLAMINO- AND 3-CYCLOALKYLAMINO-5,6-DIPHENYLPYRIDAZINES ACTIVE AS ACAT INHIBITORS 171
AIRWAY RELAXANT AND ANTI-INFLAMMATORY PROPERTIES OF A PDE 4 INHIBITOR WITH LOW AFFINITY FOR THE HIGH-AFFINITY ROLIPRAM BINDING SITE 171
PHOSPHODIESTERASE 4 INHIBITORS, STRUCTURALLY UNRELATED TO ROLIPRAM, AS PROMISING AGENTS FOR THE TREATMENT OF ASTHMA AND OTHER PATHOLOGIES 168
4-amino-5-vinyl-3(2H)-pyridazinones and analogues as potent antinociceptive agents: synthesis, SARs, and preliminary studies on the mechanism of action 168
A NEW TWO-STEP PROCEDURE FOR FUNCTIONALIZED-3(2H)-PIRIDAZINONES THROUGH HOMOLYTIC SUBSTITUTION OF 3-CHLOROPYRIDAZINES 168
Synthesis, biological evaluation, molecular modeling, and structural analysis of new pyrazole and pyrazolone derivatives as N-formyl peptide receptors agonists 168
Diels-Alder Reactions on 5-Acetyl-2-methyl-4-nitro-6-phenylpyridazin-3(2H)-one: a New Facet of the Pyridazine System 167
'Proximity frequencies' a new parameter to evaluate the profile of GABAAR modulators 167
Novel formyl peptide receptor (FPR) agonists with pyridinone and pyrimidindione scaffolds that are potentially useful for the treatment of rheumatoid arthritis 167
Editorial: Serine protease inhibitors and their therapeutic applications 166
New 3-unsubstituted Isoxazolones as Potent Human Neutrophil Elastase Inhibitors: Synthesis and Molecular Dynamic Simulation 165
5,6-DINITROPHENYL AND 5-AMINOPHENYL-6-NITROPHENYL ANALOGUES OF THE ACAT INHIBITOR 5,6-DIPHENYL-3-ALKYLAMINOPYRIDAZINONES 162
Presynaptic Cholinergic Modulators as Potent Cognition Enhancers and Analgesic Drugs. 1. Tropic and 2-Phenylpropionic Acid Esters 162
Anti-Inflammatory Activity of Pyrazolo[1,5-a]quinazolines 159
4,5-FUNCTIONALIZED-3(2H)PYRIDAZINONES: NEW SYNTHETIC AND PHARMACOLOGICAL ASPECTS 159
5-Acyl-6-aryl-4-nitro-3(2H)pyridazinones and related 4-amino compounds: synthesis and pharmacological evaluation 159
Nonsteroidal Anti-Inflammatory Drugs-1-Phenylethylamine Diastereomeric Salts: A Systematic Solid-State Investigation 157
PDE5 Inhibitors and their applications 155
Further studies on arylpiperazinyl alkyl pyridazinones: discovery of an exceptionally potent, orally active, antinociceptive agent in thermally induced pain. 154
Pyrazolo[1',5':1,6]pyrimido[4,5-d]pyridazin-4(3H)-ones as selective human A1 adenosine receptor ligands 153
New pyrazolo[1',5':1,6]pyridazin-4(3H)-ones as potent and selective PDE5 inhibitors 153
MONO- AND DI-SUBSTITUTED 5,6-DIPHENYL-3-ALKYLAMINO-PYRIDAZINES ACTIVE AS ACAT INHIBITORS 152
New 3,6-disubstituted pyrazolo[1,5-a]quinazolines as ligands to GABAA receptor subtype 152
NOVEL HETEROCYCLIC-FUSED PYRIDAZINONES AS POTENT AND SELECTIVE PHOSPHODIESTERASE IV INHIBITORS 151
A patenting perspective on human neutrophil elastase (HNE) inhibitors (2014-2018) and their therapeutic applications 150
HETEROCYCLIC-FUSED 3(2H)-PYRIDAZINONES AS POTENT AND SELECTIVE PDE IV INHIBITORS: FURTHER STRUCTURE-ACTIVITY RELATIONSHIPS AND MOLECULAR MODELLING STUDIES 148
New Panx-1 Blockers: Synthesis, Biological Evaluation and Molecular Dynamic Studies 144
SYNTHESIS AND EVALUATION OF SOME PYRAZOLO[3,4-D]PYRIDAZINONES AND ANALOGUES AS PDE5 INHIBITORS POTENTIALLY USEFUL AS PERIPHERAL VASODILATOR 141
INDENOPYRIDAZINONE DERIVATIVES AS POTENTIAL ANTISECRETORY AND ANTIULCER AGENTS 140
iVS analysis to evaluate the impact of scaffold diversity in the binding to cellular targets relevant in cancer 139
Pyridazinones and Structurally Related Derivatives with Anti-Inflammatory Activity 138
4-amino-5-vinyl-3(2H)-pyridazinones and related compounds: synthesis and evaluation of antinociceptive activity 136
Ebselen analogues with dual human neutrophil elastase (HNE) inhibitory and antiradical activity 135
SYNTHESIS AND EVALUATION AS PLATELET AGGREGATION INHIBITORS OF 6-PHENYL-2,4-SUBSTITUTED-3(2H)-PYRIDAZINONES AND THEIR RIGID ANALOGUES BENZO[H]CINNOLIN-3,5-DIONES 135
4,5-Dihydro-5-Oxo-Pyrazolo[1,5-a]Thieno[2,3-c]Pyrimidine: A Novel Scaffold Containing Thiophene Ring. Chemical Reactivity and In Silico Studies to Predict the Profile to GABAA Receptor Subtype 134
Novel Sulfonamide Analogs of Sivelestat as Potent Human Neutrophil Elastase Inhibitors 133
3,8-Disubstituted Pyrazolo[1,5-a]quinazoline as GABAA Receptor Modulators: Synthesis, Electrophysiological Assays, and Molecular Modelling Studies 132
5,6-diphenylpyridazine derivatives as acyl-CoA:cholesterol acyltranferase inhibitors 132
Design and synthesis of the first indole-based blockers of Panx-1 channel 131
SYNTHESIS AND EVALUATION OF SOME 4,5-DISUBSTITUTED 6-PHENYL-3(2H)-PYRIDAZINONES AS HYPOTENSIVE AGENTS 131
Alpha-2-agonist as analgesic agents 129
Pyrazolo[1,5-a]quinazoline scaffold as 5-deaza analogue of pyrazolo[5,1-c][1,2,4]benzotriazine system: synthesis of new derivatives, biological activity on GABAA receptor subtype and molecular dynamic study 129
Novel pyrazolopyrimidopyridazinones with potent and selective phosphodiesterase 5 (PDE5) inhibitory activity agents as potential agents for treatment of erectile dysfunction 128
Preparation of pyridazin-3(2H)-ones and their use as PDE4 inhibitors 126
GABAA receptor modulators with a pyrazolo[1,5-a]quinazoline core: synthesis, molecular modelling studies and electrophysiological assay 125
New insights on the arylpiperazinylalkyl pyridazinone ET1 as potent antinociceptive and anti-inflammatory agent 124
X-ray structural study of human neutrophil elastase inhibition with a series of azaindoles, azaindazoles and isoxazolones 122
Reductive cleavage of isoxazolo[3,4-d]pyridazinones: a synthetic approach to various 4,5-functionalized 3(2H)-pyridazinones 121
phenylpiperazinylalkylamino substituted pyridazinones as potent alpha 1 adrenoceptor antagonists 121
Synthesis and evaluation of novel pyrrolo[2,3-d] and thieno[2,3-d]pyridazinones as in vitro antiproliferative agents 120
Ligand Growing Experiments Suggested 4-amino and 4-ureido pyridazin-3(2H)-one as Novel Scaffold for FABP4 Inhibition 119
New quinoline-based PDE4 inhibitors through GSK-256066 fragment-based elaboration 119
Totale 19.095
Categoria #
all - tutte 54.847
article - articoli 0
book - libri 0
conference - conferenze 0
curatela - curatele 0
other - altro 0
patent - brevetti 0
selected - selezionate 0
volume - volumi 0
Totale 54.847


Totale Lug Ago Sett Ott Nov Dic Gen Feb Mar Apr Mag Giu
2021/2022756 19 51 43 34 29 45 22 51 34 54 183 191
2022/20231.895 187 354 78 137 186 335 240 121 157 6 66 28
2023/2024668 19 79 123 37 37 103 15 149 14 52 28 12
2024/20255.513 180 529 275 768 1.627 748 109 240 519 125 182 211
2025/20266.504 681 905 712 414 599 224 811 273 533 388 216 748
2026/202724 24 0 0 0 0 0 0 0 0 0 0 0
Totale 20.957