GIOVANNONI, MARIA PAOLA
 Distribuzione geografica
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Continente #
NA - Nord America 9.295
EU - Europa 6.912
AS - Asia 4.223
SA - Sud America 464
Continente sconosciuto - Info sul continente non disponibili 242
AF - Africa 99
OC - Oceania 62
Totale 21.297
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Nazione #
US - Stati Uniti d'America 9.148
PL - Polonia 2.161
RU - Federazione Russa 1.781
SG - Singapore 1.163
IT - Italia 1.098
CN - Cina 1.078
HK - Hong Kong 779
VN - Vietnam 408
SE - Svezia 400
IE - Irlanda 398
BR - Brasile 369
KR - Corea 351
DE - Germania 229
GB - Regno Unito 198
UA - Ucraina 191
FI - Finlandia 170
FR - Francia 157
IN - India 118
CA - Canada 94
AU - Australia 62
BD - Bangladesh 57
ID - Indonesia 53
JO - Giordania 43
NL - Olanda 36
JP - Giappone 33
TR - Turchia 27
BE - Belgio 24
AR - Argentina 23
MX - Messico 23
CI - Costa d'Avorio 22
ES - Italia 22
IQ - Iraq 19
EC - Ecuador 17
ZA - Sudafrica 17
CO - Colombia 16
NG - Nigeria 12
CH - Svizzera 11
UZ - Uzbekistan 11
VE - Venezuela 11
PK - Pakistan 10
EG - Egitto 9
PY - Paraguay 8
SC - Seychelles 8
CL - Cile 7
KZ - Kazakistan 7
SA - Arabia Saudita 7
DZ - Algeria 6
KE - Kenya 6
PE - Perù 6
PH - Filippine 6
BO - Bolivia 5
IR - Iran 5
LV - Lettonia 5
TN - Tunisia 5
AE - Emirati Arabi Uniti 4
AT - Austria 4
LA - Repubblica Popolare Democratica del Laos 4
MA - Marocco 4
MY - Malesia 4
NP - Nepal 4
TT - Trinidad e Tobago 4
AL - Albania 3
CR - Costa Rica 3
CW - ???statistics.table.value.countryCode.CW??? 3
HN - Honduras 3
JM - Giamaica 3
LB - Libano 3
LK - Sri Lanka 3
NI - Nicaragua 3
NO - Norvegia 3
OM - Oman 3
PA - Panama 3
PS - Palestinian Territory 3
RO - Romania 3
SV - El Salvador 3
TW - Taiwan 3
XK - ???statistics.table.value.countryCode.XK??? 3
AZ - Azerbaigian 2
BJ - Benin 2
BY - Bielorussia 2
CZ - Repubblica Ceca 2
DK - Danimarca 2
ET - Etiopia 2
GE - Georgia 2
GT - Guatemala 2
QA - Qatar 2
RS - Serbia 2
SN - Senegal 2
SY - Repubblica araba siriana 2
TH - Thailandia 2
UY - Uruguay 2
AM - Armenia 1
BB - Barbados 1
BG - Bulgaria 1
BH - Bahrain 1
EE - Estonia 1
EU - Europa 1
GD - Grenada 1
GR - Grecia 1
HR - Croazia 1
Totale 21.043
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Città #
Warsaw 2.157
Santa Clara 1.991
Ashburn 999
Singapore 812
Hong Kong 672
Fairfield 648
San Jose 511
Chandler 455
Dublin 396
Seoul 344
Seattle 323
Jacksonville 277
Woodbridge 263
Cambridge 259
Hefei 257
Buffalo 255
Council Bluffs 231
Houston 230
Beijing 223
Wilmington 195
Milan 191
Los Angeles 164
Ann Arbor 155
Florence 153
Ho Chi Minh City 132
Princeton 108
Altamura 106
Lawrence 101
Lauterbourg 98
Rome 97
The Dalles 93
Dallas 85
Hanoi 79
Moscow 71
Mumbai 70
Boardman 69
Munich 63
Boston 62
Medford 61
Melbourne 58
Helsinki 55
Shanghai 55
New York 49
Jakarta 46
San Diego 43
Kent 37
Dong Ket 33
Paris 33
London 31
Bologna 30
Tokyo 30
São Paulo 26
West Jordan 25
Naples 24
Brussels 23
Chicago 23
Abidjan 22
Philadelphia 22
Phoenix 22
Turku 22
Orem 21
Da Nang 20
Figino 20
Toronto 20
Turin 19
Lappeenranta 18
Clifton 16
Frankfurt am Main 16
Guangzhou 16
Izmir 16
Norwalk 16
Palermo 16
Redondo Beach 16
Brooklyn 15
Hillsboro 15
Haiphong 14
Baghdad 13
Barcelona 13
Columbus 13
Curitiba 13
Frankfurt Am Main 13
Verona 13
Yubileyny 13
Bengaluru 12
Amsterdam 11
Genoa 11
Montreal 11
Abuja 10
Austin 10
Belo Horizonte 10
Guayaquil 10
Manchester 10
Tashkent 10
Tianjin 10
Groningen 9
Johannesburg 9
Shenzhen 9
Bogotá 8
Chennai 8
Dhaka 8
Totale 14.696
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Nome #
[(3-chlorophenyl)piperazinylpropyl]pyridazinones and analogues as potent antinociceptive agents 445
Isoxazolo-5(2H)-one: a new scaffold for potent human neutrophil elastase (HNE) inhibitors 351
Synthesis, HPLC enantioresolution and X-ray analysis of a new series of C5-methyl pyridazines as N-formyl peptide receptor (FPR) agonists 345
Optimization of N-benzoylindazole derivatives as inhibitors of human neutrophil elastase 330
Synthesis and analytical characterization of new thiazol-2-(3H)-ones as human neutrophil elastase (HNE) inhibitors 325
Synthesis and evaluation as PDE4 inhibitors of pyrimidine-2,4-dione derivatives 315
Identification of a new pyrazolo[1,5-a]quinazoline ligand highly affine to γ-aminobutyric type A (GABAA) receptor subtype with anxiolytic-like and antihyperalgesic activity 305
Presynaptic Cholinergic Modulators as Potent Cognition Enhancers and Analgesic Drugs. 2. 2-Phenoxy-, 2-(phenylthio)- and 2-(phenylamino)alkanoic Acid Esters 303
Design, synthesis and evaluation of N-benzoylindazole derivatives and analogues as inhibitors of human neutrophil elastase 303
Synthesis and evaluation as antitubercular agents of 5-arylethenyl and 5-(hetero)aryl-3-isoxazolecarboxylate 301
Further studies on 2-arylacetamide pyridazin-3(2H)-ones: design, synthesis and evaluation of 4,6-disubstituted analogs as formyl peptide receptors (FPRs) agonists. 299
Synthesis and pharmacological evaluation of new pyridazin-based thioderivatives as formyl peptide receptor (FPR) agonists 282
α2 Adrenoceptor: a Target for Neuropathic Pain Treatment 280
2-Arylacetamido-4-phenylamino-5-substituted pyridazinones as formyl peptide receptors agonists. 277
Development of small molecule non-peptide formyl peptide receptor (FPR) ligands and molecular modeling of their recognition 271
New pyrazolo[1',5':1,6]pyrimido[4,5-d]pyridazin-4-(3H)-ones fluoroderivatives as human A1 adenosine receptor ligands 266
Synthesis, enantioresolution and activity profile of chiral 6-methyl-2,4-disubstituted pyridazin-3(2H)-ones as potent N-formyl peptide receptor agonists. 266
Synthesis of five and six-membered heterocycles bearing an arylpiperazinylalkyl side chain as orally active antinociceptive agents 258
Synthesis and pharmacological evaluation of indole derivatives as deaza analogues of potent human neutrophil elastase inhibitors 252
Synthesis and pharmacological evaluation of novel GABAA subtype receptor ligands with potential anxiolytic-like and anti-hyperlagesic effect 243
An Overview of PDE4 Inhibitors in Clinical Trials: 2010 to Early 2022 233
Synthesis, biological evaluation, and molecular modelling studies of potent human neutrophil elastase (HNE) inhibitors 227
A combined crystallographic and computational study on dexketoprofen trometamol dihydrate salt 227
Synthesis of five and six-membered N-phenylacetamido substituted heterocycles as formyl peptide receptor agonists 225
Synthesis of New GABAA Receptor Modulator with Pyrazolo[1,5-a]quinazoline (PQ) Scaffold 222
ANTINOCICEPTIVE ACTIVITY OF A 3(2H)-PYRIDAZINONE DERIVATE IN MICE 217
CHIRAL RESOLUTION AND ABSOLUTE CONFIGURATION OF THE ENANTIOMERS OF 5-ACETYL-2-METHYL-4-METHYLSULFINYL-6-PHENYL-3(2H)-PYRIDAZINONE AND EVALUATION OF THEIR PLATELET AGGREGATION INHIBITORY ACTIVITY 216
Further studies on pyrazolo[1',5':1,6]pyrimido[4,5-d]pyridazin-4(3H)-ones as potent and selective human A1 adenosine receptor antagonists. 216
Effects of the neutrophil elastase inhibitor EL-17 in rat adjuvant-induced arthritis. 215
4-SUBSTITUTED-5-ACETYL-2-METHYL-6-PHENYL-3(2H)PYRIDAZINONES AS PGE2 AND IL-1 RELEASE INHIBITORS FROM MOUSE ADHERENT MACROPHAGES 214
Synthesis of pyrrolo[2,3-d]pyridazinones as potent, subtype selective PDE4 inhibitors 213
1H-pyrrolo[2,3-b]pyridine: a new scaffold for human neutrophil elastase (HNE) inhibitors 211
5-ACETYL-2-METHYL-4-NITRO-6-PHENYL-3(2H)-PYRIDAZINONE:VERSATILE PRECURSOR TO HETERO-CONDENSED PYRIDAZINONES 209
Exploration of Nitrogen Heterocycle Scaffolds for the Development of Potent Human Neutrophil Elastase Inhibitors 206
4-Amino-5-substituted-3(2H)-pyridazinones as orally active antinociceptive agents: synthesis and studies on the mechanism of action 205
Further modifications of 1H-pyrrolo[2,3-b]pyridine derivatives as inhibitors of human neutrophil elastase 202
Cinnoline derivatives as human neutrophil elastase inhibitors 198
1,5,6,7-Tetrahydro-4H-indazol-4-ones as human neutrophil elastase (HNE) inhibitors 195
Arylpiperazinylalkylpyridazinones and analogues as potent and orally active antinociceptive agents: synthesis and studies on mechanism of action 192
4,5-FUNCTIONALIZED 6-PHENYL-3(2H)-PIRIDAZINONES:SYNTHESIS AND EVALUATION OF ANTINOCICEPTIVE ACTIVITY 186
6-Methyl-2,4-disubstituted pyridazin-3(2H)-ones: a novel class of small-molecule agonists for formyl peptide receptors. 186
Functionalized pyrazoles and pyrazolo[3,4-d]pyridazinones: synthesis and evaluation of their phosphodiesterase 4 inhibitory activity 186
Design, Synthesis and Pharmacological Evaluation of New Quinoline-Based Panx-1 Channel Blockers 184
4-AMINO-3(2H)-PYRIDAZINONES BEARING ARYLPIPERAZINYLALKYL GROUPS AND RELATED COMPOUNDS: SYNTHESIS AND ANTINOCICEPTIVE ACTIVITY 184
ISOXAZOLO[3,4-D]PYRIDAZIN-7-(6H)-ONE AS A POTENTIAL SUBSTRATE FOR NEW ALDOSE REDUCTASE INHIBITORS 181
SELECTIVE ACAT INHIBITORS AS PROMISING ANTIHYPERLIPIDEMIC, ANTIATHEROSCLEROTIC AND ANTI-ALZHEIMER DRUGS 178
ISOXAZOLO[3,4-D]PYRIDAZINONES AND ANALOGUES AS LEISHMANIA MEXICANA PDE INHIBITORS 177
Protective and Pain-Killer Effects of AMC3, a Novel N-Formyl Peptide Receptors (FPRs) Modulator, in Experimental Models of Rheumatoid Arthritis 174
AIRWAY RELAXANT AND ANTI-INFLAMMATORY PROPERTIES OF A PDE 4 INHIBITOR WITH LOW AFFINITY FOR THE HIGH-AFFINITY ROLIPRAM BINDING SITE 174
NOVEL 3-ARYLAMINO- AND 3-CYCLOALKYLAMINO-5,6-DIPHENYLPYRIDAZINES ACTIVE AS ACAT INHIBITORS 173
A NEW TWO-STEP PROCEDURE FOR FUNCTIONALIZED-3(2H)-PIRIDAZINONES THROUGH HOMOLYTIC SUBSTITUTION OF 3-CHLOROPYRIDAZINES 172
4-amino-5-vinyl-3(2H)-pyridazinones and analogues as potent antinociceptive agents: synthesis, SARs, and preliminary studies on the mechanism of action 171
PHOSPHODIESTERASE 4 INHIBITORS, STRUCTURALLY UNRELATED TO ROLIPRAM, AS PROMISING AGENTS FOR THE TREATMENT OF ASTHMA AND OTHER PATHOLOGIES 169
Diels-Alder Reactions on 5-Acetyl-2-methyl-4-nitro-6-phenylpyridazin-3(2H)-one: a New Facet of the Pyridazine System 169
'Proximity frequencies' a new parameter to evaluate the profile of GABAAR modulators 169
Novel formyl peptide receptor (FPR) agonists with pyridinone and pyrimidindione scaffolds that are potentially useful for the treatment of rheumatoid arthritis 169
Editorial: Serine protease inhibitors and their therapeutic applications 168
New 3-unsubstituted Isoxazolones as Potent Human Neutrophil Elastase Inhibitors: Synthesis and Molecular Dynamic Simulation 168
Synthesis, biological evaluation, molecular modeling, and structural analysis of new pyrazole and pyrazolone derivatives as N-formyl peptide receptors agonists 168
5,6-DINITROPHENYL AND 5-AMINOPHENYL-6-NITROPHENYL ANALOGUES OF THE ACAT INHIBITOR 5,6-DIPHENYL-3-ALKYLAMINOPYRIDAZINONES 165
Presynaptic Cholinergic Modulators as Potent Cognition Enhancers and Analgesic Drugs. 1. Tropic and 2-Phenylpropionic Acid Esters 165
Anti-Inflammatory Activity of Pyrazolo[1,5-a]quinazolines 164
4,5-FUNCTIONALIZED-3(2H)PYRIDAZINONES: NEW SYNTHETIC AND PHARMACOLOGICAL ASPECTS 161
5-Acyl-6-aryl-4-nitro-3(2H)pyridazinones and related 4-amino compounds: synthesis and pharmacological evaluation 161
Nonsteroidal Anti-Inflammatory Drugs-1-Phenylethylamine Diastereomeric Salts: A Systematic Solid-State Investigation 160
PDE5 Inhibitors and their applications 159
New 3,6-disubstituted pyrazolo[1,5-a]quinazolines as ligands to GABAA receptor subtype 157
Pyrazolo[1',5':1,6]pyrimido[4,5-d]pyridazin-4(3H)-ones as selective human A1 adenosine receptor ligands 155
NOVEL HETEROCYCLIC-FUSED PYRIDAZINONES AS POTENT AND SELECTIVE PHOSPHODIESTERASE IV INHIBITORS 155
MONO- AND DI-SUBSTITUTED 5,6-DIPHENYL-3-ALKYLAMINO-PYRIDAZINES ACTIVE AS ACAT INHIBITORS 155
Further studies on arylpiperazinyl alkyl pyridazinones: discovery of an exceptionally potent, orally active, antinociceptive agent in thermally induced pain. 155
New pyrazolo[1',5':1,6]pyridazin-4(3H)-ones as potent and selective PDE5 inhibitors 154
A patenting perspective on human neutrophil elastase (HNE) inhibitors (2014-2018) and their therapeutic applications 152
HETEROCYCLIC-FUSED 3(2H)-PYRIDAZINONES AS POTENT AND SELECTIVE PDE IV INHIBITORS: FURTHER STRUCTURE-ACTIVITY RELATIONSHIPS AND MOLECULAR MODELLING STUDIES 149
New Panx-1 Blockers: Synthesis, Biological Evaluation and Molecular Dynamic Studies 145
SYNTHESIS AND EVALUATION OF SOME PYRAZOLO[3,4-D]PYRIDAZINONES AND ANALOGUES AS PDE5 INHIBITORS POTENTIALLY USEFUL AS PERIPHERAL VASODILATOR 142
iVS analysis to evaluate the impact of scaffold diversity in the binding to cellular targets relevant in cancer 142
INDENOPYRIDAZINONE DERIVATIVES AS POTENTIAL ANTISECRETORY AND ANTIULCER AGENTS 141
Pyridazinones and Structurally Related Derivatives with Anti-Inflammatory Activity 140
Alpha-2-agonist as analgesic agents 139
Ebselen analogues with dual human neutrophil elastase (HNE) inhibitory and antiradical activity 138
Design and synthesis of the first indole-based blockers of Panx-1 channel 138
4-amino-5-vinyl-3(2H)-pyridazinones and related compounds: synthesis and evaluation of antinociceptive activity 138
SYNTHESIS AND EVALUATION AS PLATELET AGGREGATION INHIBITORS OF 6-PHENYL-2,4-SUBSTITUTED-3(2H)-PYRIDAZINONES AND THEIR RIGID ANALOGUES BENZO[H]CINNOLIN-3,5-DIONES 137
Novel Sulfonamide Analogs of Sivelestat as Potent Human Neutrophil Elastase Inhibitors 137
4,5-Dihydro-5-Oxo-Pyrazolo[1,5-a]Thieno[2,3-c]Pyrimidine: A Novel Scaffold Containing Thiophene Ring. Chemical Reactivity and In Silico Studies to Predict the Profile to GABAA Receptor Subtype 136
5,6-diphenylpyridazine derivatives as acyl-CoA:cholesterol acyltranferase inhibitors 136
3,8-Disubstituted Pyrazolo[1,5-a]quinazoline as GABAA Receptor Modulators: Synthesis, Electrophysiological Assays, and Molecular Modelling Studies 134
SYNTHESIS AND EVALUATION OF SOME 4,5-DISUBSTITUTED 6-PHENYL-3(2H)-PYRIDAZINONES AS HYPOTENSIVE AGENTS 134
Novel pyrazolopyrimidopyridazinones with potent and selective phosphodiesterase 5 (PDE5) inhibitory activity agents as potential agents for treatment of erectile dysfunction 133
Pyrazolo[1,5-a]quinazoline scaffold as 5-deaza analogue of pyrazolo[5,1-c][1,2,4]benzotriazine system: synthesis of new derivatives, biological activity on GABAA receptor subtype and molecular dynamic study 131
Preparation of pyridazin-3(2H)-ones and their use as PDE4 inhibitors 128
GABAA receptor modulators with a pyrazolo[1,5-a]quinazoline core: synthesis, molecular modelling studies and electrophysiological assay 126
New insights on the arylpiperazinylalkyl pyridazinone ET1 as potent antinociceptive and anti-inflammatory agent 125
X-ray structural study of human neutrophil elastase inhibition with a series of azaindoles, azaindazoles and isoxazolones 124
phenylpiperazinylalkylamino substituted pyridazinones as potent alpha 1 adrenoceptor antagonists 124
Reductive cleavage of isoxazolo[3,4-d]pyridazinones: a synthetic approach to various 4,5-functionalized 3(2H)-pyridazinones 123
New quinoline-based PDE4 inhibitors through GSK-256066 fragment-based elaboration 122
Synthesis and evaluation of novel pyrrolo[2,3-d] and thieno[2,3-d]pyridazinones as in vitro antiproliferative agents 121
Ligand Growing Experiments Suggested 4-amino and 4-ureido pyridazin-3(2H)-one as Novel Scaffold for FABP4 Inhibition 120
Totale 19.387
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Categoria #
all - tutte 56.893
article - articoli 0
book - libri 0
conference - conferenze 0
curatela - curatele 0
other - altro 0
patent - brevetti 0
selected - selezionate 0
volume - volumi 0
Totale 56.893
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Totale Lug Ago Sett Ott Nov Dic Gen Feb Mar Apr Mag Giu
2021/2022737 0 51 43 34 29 45 22 51 34 54 183 191
2022/20231.895 187 354 78 137 186 335 240 121 157 6 66 28
2023/2024668 19 79 123 37 37 103 15 149 14 52 28 12
2024/20255.513 180 529 275 768 1.627 748 109 240 519 125 182 211
2025/20266.504 681 905 712 414 599 224 811 273 533 388 216 748
2026/2027364 181 183 0 0 0 0 0 0 0 0 0 0
Totale 21.297