GIOVANNONI, MARIA PAOLA
 Distribuzione geografica
Continente #
NA - Nord America 7.830
EU - Europa 6.030
AS - Asia 3.406
SA - Sud America 433
AF - Africa 77
OC - Oceania 61
Continente sconosciuto - Info sul continente non disponibili 4
Totale 17.841
Nazione #
US - Stati Uniti d'America 7.777
PL - Polonia 2.160
RU - Federazione Russa 1.779
SG - Singapore 991
CN - Cina 862
HK - Hong Kong 739
IT - Italia 404
SE - Svezia 400
IE - Irlanda 396
BR - Brasile 352
KR - Corea 347
DE - Germania 220
UA - Ucraina 189
GB - Regno Unito 179
FI - Finlandia 143
VN - Vietnam 141
IN - India 102
AU - Australia 61
FR - Francia 51
ID - Indonesia 50
JO - Giordania 42
NL - Olanda 28
CA - Canada 27
TR - Turchia 25
BE - Belgio 24
AR - Argentina 22
CI - Costa d'Avorio 22
JP - Giappone 20
ES - Italia 18
MX - Messico 16
EC - Ecuador 15
ZA - Sudafrica 15
IQ - Iraq 13
BD - Bangladesh 12
CO - Colombia 12
CH - Svizzera 10
VE - Venezuela 10
UZ - Uzbekistan 9
EG - Egitto 8
SC - Seychelles 8
PY - Paraguay 7
KE - Kenya 6
KZ - Kazakistan 6
SA - Arabia Saudita 6
IR - Iran 5
LV - Lettonia 5
PE - Perù 5
PK - Pakistan 5
TN - Tunisia 5
BO - Bolivia 4
CL - Cile 4
LA - Repubblica Popolare Democratica del Laos 4
PH - Filippine 4
AE - Emirati Arabi Uniti 3
AL - Albania 3
AT - Austria 3
DZ - Algeria 3
NO - Norvegia 3
OM - Oman 3
PA - Panama 3
RO - Romania 3
XK - ???statistics.table.value.countryCode.XK??? 3
BJ - Benin 2
BY - Bielorussia 2
CZ - Repubblica Ceca 2
DK - Danimarca 2
LB - Libano 2
LK - Sri Lanka 2
MA - Marocco 2
MY - Malesia 2
QA - Qatar 2
TT - Trinidad e Tobago 2
UY - Uruguay 2
AM - Armenia 1
BB - Barbados 1
BG - Bulgaria 1
BH - Bahrain 1
EE - Estonia 1
ET - Etiopia 1
EU - Europa 1
GR - Grecia 1
GT - Guatemala 1
JM - Giamaica 1
KG - Kirghizistan 1
KH - Cambogia 1
KW - Kuwait 1
MK - Macedonia 1
MM - Myanmar 1
MU - Mauritius 1
NG - Nigeria 1
NI - Nicaragua 1
NP - Nepal 1
PS - Palestinian Territory 1
RS - Serbia 1
SK - Slovacchia (Repubblica Slovacca) 1
SN - Senegal 1
SO - Somalia 1
SV - El Salvador 1
TW - Taiwan 1
ZW - Zimbabwe 1
Totale 17.841
Città #
Warsaw 2.156
Santa Clara 1.940
Ashburn 686
Singapore 650
Fairfield 648
Hong Kong 644
Chandler 455
Dublin 394
Seoul 344
Seattle 318
Jacksonville 276
Woodbridge 261
Cambridge 256
Hefei 256
Buffalo 251
Houston 228
Beijing 209
Wilmington 195
Ann Arbor 155
Los Angeles 147
Florence 137
Princeton 108
Altamura 106
Lawrence 101
Dallas 77
San Jose 75
Moscow 71
Mumbai 67
Boardman 66
Munich 63
Boston 62
Medford 61
Melbourne 58
Council Bluffs 52
Shanghai 49
Jakarta 45
Ho Chi Minh City 44
The Dalles 44
New York 42
San Diego 40
Kent 37
Dong Ket 33
Helsinki 29
Paris 29
London 27
São Paulo 25
West Jordan 25
Brussels 23
Abidjan 22
Turku 22
Philadelphia 20
Tokyo 19
Phoenix 18
Hanoi 17
Lappeenranta 17
Chicago 16
Clifton 16
Izmir 16
Norwalk 16
Redondo Beach 16
Hillsboro 15
Barcelona 13
Brooklyn 13
Curitiba 13
Frankfurt Am Main 13
Yubileyny 13
Bengaluru 12
Toronto 12
Milan 11
Verona 11
Belo Horizonte 10
Guayaquil 10
Frankfurt am Main 9
Groningen 9
Tashkent 9
Baghdad 8
Falls Church 8
Bern 7
Guangzhou 7
Johannesburg 7
Orem 7
Rio de Janeiro 7
Rome 7
Bogotá 6
Dhaka 6
Fuzhou 6
Gavirate 6
Montreal 6
North Charleston 6
Poplar 6
Amsterdam 5
Andover 5
Chennai 5
Denver 5
Menlo Park 5
Pune 5
Riyadh 5
Secaucus 5
Shenzhen 5
Tappahannock 5
Totale 12.603
Nome #
[(3-chlorophenyl)piperazinylpropyl]pyridazinones and analogues as potent antinociceptive agents 365
Synthesis, HPLC enantioresolution and X-ray analysis of a new series of C5-methyl pyridazines as N-formyl peptide receptor (FPR) agonists 315
Isoxazolo-5(2H)-one: a new scaffold for potent human neutrophil elastase (HNE) inhibitors 311
Synthesis and analytical characterization of new thiazol-2-(3H)-ones as human neutrophil elastase (HNE) inhibitors 306
Further studies on 2-arylacetamide pyridazin-3(2H)-ones: design, synthesis and evaluation of 4,6-disubstituted analogs as formyl peptide receptors (FPRs) agonists. 277
Presynaptic Cholinergic Modulators as Potent Cognition Enhancers and Analgesic Drugs. 2. 2-Phenoxy-, 2-(phenylthio)- and 2-(phenylamino)alkanoic Acid Esters 272
Synthesis and evaluation as PDE4 inhibitors of pyrimidine-2,4-dione derivatives 270
Identification of a new pyrazolo[1,5-a]quinazoline ligand highly affine to γ-aminobutyric type A (GABAA) receptor subtype with anxiolytic-like and antihyperalgesic activity 268
Synthesis and evaluation as antitubercular agents of 5-arylethenyl and 5-(hetero)aryl-3-isoxazolecarboxylate 263
Design, synthesis and evaluation of N-benzoylindazole derivatives and analogues as inhibitors of human neutrophil elastase 263
Synthesis and pharmacological evaluation of new pyridazin-based thioderivatives as formyl peptide receptor (FPR) agonists 258
α2 Adrenoceptor: a Target for Neuropathic Pain Treatment 256
Development of small molecule non-peptide formyl peptide receptor (FPR) ligands and molecular modeling of their recognition 248
Synthesis, enantioresolution and activity profile of chiral 6-methyl-2,4-disubstituted pyridazin-3(2H)-ones as potent N-formyl peptide receptor agonists. 235
2-Arylacetamido-4-phenylamino-5-substituted pyridazinones as formyl peptide receptors agonists. 234
Synthesis of five and six-membered heterocycles bearing an arylpiperazinylalkyl side chain as orally active antinociceptive agents 231
Optimization of N-benzoylindazole derivatives as inhibitors of human neutrophil elastase 228
Synthesis and pharmacological evaluation of novel GABAA subtype receptor ligands with potential anxiolytic-like and anti-hyperlagesic effect 224
New pyrazolo[1',5':1,6]pyrimido[4,5-d]pyridazin-4-(3H)-ones fluoroderivatives as human A1 adenosine receptor ligands 223
Synthesis and pharmacological evaluation of indole derivatives as deaza analogues of potent human neutrophil elastase inhibitors 221
Synthesis of five and six-membered N-phenylacetamido substituted heterocycles as formyl peptide receptor agonists 198
CHIRAL RESOLUTION AND ABSOLUTE CONFIGURATION OF THE ENANTIOMERS OF 5-ACETYL-2-METHYL-4-METHYLSULFINYL-6-PHENYL-3(2H)-PYRIDAZINONE AND EVALUATION OF THEIR PLATELET AGGREGATION INHIBITORY ACTIVITY 193
Further studies on pyrazolo[1',5':1,6]pyrimido[4,5-d]pyridazin-4(3H)-ones as potent and selective human A1 adenosine receptor antagonists. 193
ANTINOCICEPTIVE ACTIVITY OF A 3(2H)-PYRIDAZINONE DERIVATE IN MICE 192
Synthesis, biological evaluation, and molecular modelling studies of potent human neutrophil elastase (HNE) inhibitors 192
A combined crystallographic and computational study on dexketoprofen trometamol dihydrate salt 191
4-SUBSTITUTED-5-ACETYL-2-METHYL-6-PHENYL-3(2H)PYRIDAZINONES AS PGE2 AND IL-1 RELEASE INHIBITORS FROM MOUSE ADHERENT MACROPHAGES 190
Synthesis of New GABAA Receptor Modulator with Pyrazolo[1,5-a]quinazoline (PQ) Scaffold 187
1H-pyrrolo[2,3-b]pyridine: a new scaffold for human neutrophil elastase (HNE) inhibitors 184
5-ACETYL-2-METHYL-4-NITRO-6-PHENYL-3(2H)-PYRIDAZINONE:VERSATILE PRECURSOR TO HETERO-CONDENSED PYRIDAZINONES 180
4-Amino-5-substituted-3(2H)-pyridazinones as orally active antinociceptive agents: synthesis and studies on the mechanism of action 179
Synthesis of pyrrolo[2,3-d]pyridazinones as potent, subtype selective PDE4 inhibitors 179
Further modifications of 1H-pyrrolo[2,3-b]pyridine derivatives as inhibitors of human neutrophil elastase 179
An Overview of PDE4 Inhibitors in Clinical Trials: 2010 to Early 2022 174
Cinnoline derivatives as human neutrophil elastase inhibitors 173
Effects of the neutrophil elastase inhibitor EL-17 in rat adjuvant-induced arthritis. 172
SELECTIVE ACAT INHIBITORS AS PROMISING ANTIHYPERLIPIDEMIC, ANTIATHEROSCLEROTIC AND ANTI-ALZHEIMER DRUGS 165
ISOXAZOLO[3,4-D]PYRIDAZINONES AND ANALOGUES AS LEISHMANIA MEXICANA PDE INHIBITORS 164
ISOXAZOLO[3,4-D]PYRIDAZIN-7-(6H)-ONE AS A POTENTIAL SUBSTRATE FOR NEW ALDOSE REDUCTASE INHIBITORS 163
4-AMINO-3(2H)-PYRIDAZINONES BEARING ARYLPIPERAZINYLALKYL GROUPS AND RELATED COMPOUNDS: SYNTHESIS AND ANTINOCICEPTIVE ACTIVITY 162
4,5-FUNCTIONALIZED 6-PHENYL-3(2H)-PIRIDAZINONES:SYNTHESIS AND EVALUATION OF ANTINOCICEPTIVE ACTIVITY 161
PHOSPHODIESTERASE 4 INHIBITORS, STRUCTURALLY UNRELATED TO ROLIPRAM, AS PROMISING AGENTS FOR THE TREATMENT OF ASTHMA AND OTHER PATHOLOGIES 160
Design, Synthesis and Pharmacological Evaluation of New Quinoline-Based Panx-1 Channel Blockers 159
Arylpiperazinylalkylpyridazinones and analogues as potent and orally active antinociceptive agents: synthesis and studies on mechanism of action 159
NOVEL 3-ARYLAMINO- AND 3-CYCLOALKYLAMINO-5,6-DIPHENYLPYRIDAZINES ACTIVE AS ACAT INHIBITORS 158
Diels-Alder Reactions on 5-Acetyl-2-methyl-4-nitro-6-phenylpyridazin-3(2H)-one: a New Facet of the Pyridazine System 156
6-Methyl-2,4-disubstituted pyridazin-3(2H)-ones: a novel class of small-molecule agonists for formyl peptide receptors. 153
1,5,6,7-Tetrahydro-4H-indazol-4-ones as human neutrophil elastase (HNE) inhibitors 153
Functionalized pyrazoles and pyrazolo[3,4-d]pyridazinones: synthesis and evaluation of their phosphodiesterase 4 inhibitory activity 152
A NEW TWO-STEP PROCEDURE FOR FUNCTIONALIZED-3(2H)-PIRIDAZINONES THROUGH HOMOLYTIC SUBSTITUTION OF 3-CHLOROPYRIDAZINES 151
5,6-DINITROPHENYL AND 5-AMINOPHENYL-6-NITROPHENYL ANALOGUES OF THE ACAT INHIBITOR 5,6-DIPHENYL-3-ALKYLAMINOPYRIDAZINONES 150
5-Acyl-6-aryl-4-nitro-3(2H)pyridazinones and related 4-amino compounds: synthesis and pharmacological evaluation 150
New 3-unsubstituted Isoxazolones as Potent Human Neutrophil Elastase Inhibitors: Synthesis and Molecular Dynamic Simulation 149
4-amino-5-vinyl-3(2H)-pyridazinones and analogues as potent antinociceptive agents: synthesis, SARs, and preliminary studies on the mechanism of action 148
Presynaptic Cholinergic Modulators as Potent Cognition Enhancers and Analgesic Drugs. 1. Tropic and 2-Phenylpropionic Acid Esters 146
AIRWAY RELAXANT AND ANTI-INFLAMMATORY PROPERTIES OF A PDE 4 INHIBITOR WITH LOW AFFINITY FOR THE HIGH-AFFINITY ROLIPRAM BINDING SITE 144
Protective and Pain-Killer Effects of AMC3, a Novel N-Formyl Peptide Receptors (FPRs) Modulator, in Experimental Models of Rheumatoid Arthritis 141
Editorial: Serine protease inhibitors and their therapeutic applications 141
4,5-FUNCTIONALIZED-3(2H)PYRIDAZINONES: NEW SYNTHETIC AND PHARMACOLOGICAL ASPECTS 140
New pyrazolo[1',5':1,6]pyridazin-4(3H)-ones as potent and selective PDE5 inhibitors 140
MONO- AND DI-SUBSTITUTED 5,6-DIPHENYL-3-ALKYLAMINO-PYRIDAZINES ACTIVE AS ACAT INHIBITORS 139
HETEROCYCLIC-FUSED 3(2H)-PYRIDAZINONES AS POTENT AND SELECTIVE PDE IV INHIBITORS: FURTHER STRUCTURE-ACTIVITY RELATIONSHIPS AND MOLECULAR MODELLING STUDIES 139
Synthesis, biological evaluation, molecular modeling, and structural analysis of new pyrazole and pyrazolone derivatives as N-formyl peptide receptors agonists 137
'Proximity frequencies' a new parameter to evaluate the profile of GABAAR modulators 133
New 3,6-disubstituted pyrazolo[1,5-a]quinazolines as ligands to GABAA receptor subtype 133
Exploration of Nitrogen Heterocycle Scaffolds for the Development of Potent Human Neutrophil Elastase Inhibitors 133
Novel formyl peptide receptor (FPR) agonists with pyridinone and pyrimidindione scaffolds that are potentially useful for the treatment of rheumatoid arthritis 133
Nonsteroidal Anti-Inflammatory Drugs-1-Phenylethylamine Diastereomeric Salts: A Systematic Solid-State Investigation 132
NOVEL HETEROCYCLIC-FUSED PYRIDAZINONES AS POTENT AND SELECTIVE PHOSPHODIESTERASE IV INHIBITORS 130
Anti-Inflammatory Activity of Pyrazolo[1,5-a]quinazolines 128
Further studies on arylpiperazinyl alkyl pyridazinones: discovery of an exceptionally potent, orally active, antinociceptive agent in thermally induced pain. 128
A patenting perspective on human neutrophil elastase (HNE) inhibitors (2014-2018) and their therapeutic applications 127
INDENOPYRIDAZINONE DERIVATIVES AS POTENTIAL ANTISECRETORY AND ANTIULCER AGENTS 125
PDE5 Inhibitors and their applications 124
SYNTHESIS AND EVALUATION OF SOME 4,5-DISUBSTITUTED 6-PHENYL-3(2H)-PYRIDAZINONES AS HYPOTENSIVE AGENTS 123
SYNTHESIS AND EVALUATION AS PLATELET AGGREGATION INHIBITORS OF 6-PHENYL-2,4-SUBSTITUTED-3(2H)-PYRIDAZINONES AND THEIR RIGID ANALOGUES BENZO[H]CINNOLIN-3,5-DIONES 122
Pyrazolo[1,5-a]quinazoline scaffold as 5-deaza analogue of pyrazolo[5,1-c][1,2,4]benzotriazine system: synthesis of new derivatives, biological activity on GABAA receptor subtype and molecular dynamic study 122
Pyrazolo[1',5':1,6]pyrimido[4,5-d]pyridazin-4(3H)-ones as selective human A1 adenosine receptor ligands 121
4-amino-5-vinyl-3(2H)-pyridazinones and related compounds: synthesis and evaluation of antinociceptive activity 119
SYNTHESIS AND EVALUATION OF SOME PYRAZOLO[3,4-D]PYRIDAZINONES AND ANALOGUES AS PDE5 INHIBITORS POTENTIALLY USEFUL AS PERIPHERAL VASODILATOR 117
5,6-diphenylpyridazine derivatives as acyl-CoA:cholesterol acyltranferase inhibitors 116
Pyridazinones and Structurally Related Derivatives with Anti-Inflammatory Activity 114
4,5-Dihydro-5-Oxo-Pyrazolo[1,5-a]Thieno[2,3-c]Pyrimidine: A Novel Scaffold Containing Thiophene Ring. Chemical Reactivity and In Silico Studies to Predict the Profile to GABAA Receptor Subtype 113
Novel Sulfonamide Analogs of Sivelestat as Potent Human Neutrophil Elastase Inhibitors 112
New insights on the arylpiperazinylalkyl pyridazinone ET1 as potent antinociceptive and anti-inflammatory agent 111
New Panx-1 Blockers: Synthesis, Biological Evaluation and Molecular Dynamic Studies 111
Alpha-2-agonist as analgesic agents 108
X-ray structural study of human neutrophil elastase inhibition with a series of azaindoles, azaindazoles and isoxazolones 107
New quinoline-based PDE4 inhibitors through GSK-256066 fragment-based elaboration 107
iVS analysis to evaluate the impact of scaffold diversity in the binding to cellular targets relevant in cancer 107
Ebselen analogues with dual human neutrophil elastase (HNE) inhibitory and antiradical activity 105
Design and synthesis of the first indole-based blockers of Panx-1 channel 105
Preparation of pyridazin-3(2H)-ones and their use as PDE4 inhibitors 104
3,8-Disubstituted Pyrazolo[1,5-a]quinazoline as GABAA Receptor Modulators: Synthesis, Electrophysiological Assays, and Molecular Modelling Studies 103
Ligand Growing Experiments Suggested 4-amino and 4-ureido pyridazin-3(2H)-one as Novel Scaffold for FABP4 Inhibition 102
SYNTHESIS OF 4,5 FUNCTIONALIZED-2-METHYL-6-(SUBSTITUTED ARYL)-3(2H)-PYRIDAZINONES: A NEW GROUP OF POTENT PLATELET AGGREGATION INHIBITORS 102
New synthetic approach to pyrazolo[3,4-d]pyridazin-7(6H)-one ring system 101
Synthesis and evaluation of novel pyrrolo[2,3-d] and thieno[2,3-d]pyridazinones as in vitro antiproliferative agents 101
Novel pyrazolopyrimidopyridazinones with potent and selective phosphodiesterase 5 (PDE5) inhibitory activity agents as potential agents for treatment of erectile dysfunction 100
preparation of pyridazin-3(2H)-ones as phosphodiesterase 4 (PDE4) inhibitors 99
Totale 16.582
Categoria #
all - tutte 47.979
article - articoli 0
book - libri 0
conference - conferenze 0
curatela - curatele 0
other - altro 0
patent - brevetti 0
selected - selezionate 0
volume - volumi 0
Totale 47.979


Totale Lug Ago Sett Ott Nov Dic Gen Feb Mar Apr Mag Giu
2020/2021795 0 0 0 0 0 0 79 124 170 239 73 110
2021/2022756 19 51 43 34 29 45 22 51 34 54 183 191
2022/20231.895 187 354 78 137 186 335 240 121 157 6 66 28
2023/2024668 19 79 123 37 37 103 15 149 14 52 28 12
2024/20255.513 180 529 275 768 1.627 748 109 240 519 125 182 211
2025/20263.645 681 905 712 414 599 224 110 0 0 0 0 0
Totale 18.074