BUA, SILVIA
BUA, SILVIA
Neuroscienze, Psicologia, Area del Farmaco e Salute del Bambino (NEUROFARBA)
"a Sweet Combination": Developing Saccharin and Acesulfame K Structures for Selectively Targeting the Tumor-Associated Carbonic Anhydrases IX and XII
2020 Bua S.; Lomelino C.; Murray A.B.; Osman S.M.; Alothman Z.A.; Bozdag M.; Abdel-Aziz H.A.; Eldehna W.M.; McKenna R.; Nocentini A.; Supuran C.T.
2-Benzylpiperazine: a new scaffold for potent human Carbonic Anhydrase inhibitors. Synthesis, enzyme inhibition, enantioselectivity, computational and crystallographic studies and in vivo activity for a new class of intraocular pressure lowering agents.
2018 Niccolò Chiaramonte, Silvia Bua, Marta Ferraroni, Alessio Nocentini, Alessandro Bonardi, Gian Luca Bartolucci, Maria Concetta Durante, Laura Lucarini, Donata Chiapponi, Silvia Dei, Dina Manetti, Elisabetta Teodori, Paola Gratteri, Emanuela Masini, Claudiu T. Supuran, Maria Novella Romanelli
3-Aminobenzenesulfonamides incorporating acylthiourea moieties selectively inhibit the tumor-associated carbonic anhydrase isoform IX over the off-target isoforms I, II and IV
2019 Fattah, Tanzeela Abdul; Bua, Silvia; Saeed, Aamer; Shabir, Ghulam; Supuran, Claudiu T
3-Hydrazinoisatin-based benzenesulfonamides as novel carbonic anhydrase inhibitors endowed with anticancer activity: Synthesis, in vitro biological evaluation and in silico insights
2019 Abo-Ashour M.F.; Eldehna W.M.; Nocentini A.; Bonardi A.; Bua S.; Ibrahim H.S.; Elaasser M.M.; Krystof V.; Jorda R.; Gratteri P.; Abou-Seri S.M.; Supuran C.T.
Activation of human α-carbonic anhydrase isoforms I, II, IV and VII with bis-histamine schiff bases and bis-spinaceamine substituted derivatives
2019 Akocak S.; Lolak N.; Bua S.; Nocentini A.; Supuran C.T.
Activation Studies of the β-Carbonic Anhydrase from the Pathogenic Protozoan Entamoeba histolytica with Amino Acids and Amines
2019 Bua, Silvia; Haapanen, Susanna; Kuuslahti, Marianne; Parkkila, Seppo; Supuran, Claudiu T
Advances in New Psychoactive Substances Identification: The U.R.I.To.N Consortium
2017 Bertol, Elisabetta; Vaiano, Fabio; Mari, Francesco; Di Milia, Maria Grazia; Bua, Silvia; Supuran, Claudiu Trandafir; Carta, Fabrizio
Anticancer effects of new dibenzenesulfonamides by inducing apoptosis and autophagy pathways and their carbonic anhydrase inhibitory effects on hCA I, hCA II, hCA IX, hCA XII isoenzymes
2018 Gul, Halise Inci*; Yamali, Cem; Bulbuller, Merve; Kirmizibayrak, Petek Ballar; Gul, Mustafa; Angeli, Andrea; Bua, Silvia; Supuran, Claudiu T.
APPLICATION OF LINEAR EQUATIONS DECONVOLUTION ANALYSIS (LEDA) ALGORITHM IN ION TRAP MASS SPECTROMETRY: RESOLUTION OF ISOMERIC PAIRS OF CARBONIC ANHYDRASE AND CYCLOOXYGENASE HYBRIDS INHIBITORS
2018 Donato Squillaci; Marta Menicatti; Silvia Bua; Claudiu T. Supuran; Gian Luca Bartolucci
Benzenesulfonamide bearing imidazothiadiazole and thiazolotriazole scaffolds as potent tumor associated human carbonic anhydrase IX and XII inhibitors
2017 Kumar, Rajiv; Bua, Silvia; Ram, Sita; Del Prete, Sonia; Capasso, Clemente; Supuran, Claudiu T; Sharma, Pawan K.
Benzenesulfonamides incorporating nitrogenous bases show effective inhibition of β-carbonic anhydrases from the pathogenic fungi Cryptococcus neoformans, Candida glabrata and Malassezia globosa
2019 Bua, Silvia; Osman, Sameh M; AlOthman, Zeid; Supuran, Claudiu T; Nocentini, Alessio
Benzothiadiazinone-1,1-Dioxide Carbonic Anhydrase Inhibitors Suppress the Growth of Drug-Resistant Mycobacterium tuberculosis Strains
2024 Bua, Silvia; Bonardi, Alessandro; Mük, Georgiana Ramona; Nocentini, Alessio; Gratteri, Paola; Supuran, Claudiu T.
Benzyl alcohol inhibits carbonic anhydrases by anchoring to the zinc coordinated water molecule
2021 De Simone, Giuseppina; Bua, Silvia; Supuran, Claudiu T; Alterio, Vincenzo
Biochemical and Structural Insights into Carbonic Anhydrase XII/Fab6A10 Complex
2019 Alterio, Vincenzo; Kellner, Markus; Esposito, Davide; Liesche-Starnecker, Friederike; Bua, Silvia; Supuran, Claudiu T; Monti, Simona Maria; Zeidler, Reinhard; De Simone, Giuseppina
Biological evaluation, radiosensitizing activity and structural insights of novel halogenated quinazoline-sulfonamide conjugates as selective human carbonic anhydrases IX/XII inhibitors
2021 Ghorab, Mostafa M; Soliman, Aiten M; Bua, Silvia; Supuran, Claudiu T
Calixarenes Incorporating Sulfonamide Moieties: Versatile Ligands for Carbonic Anhydrases Inhibition
2022 Sbravati D.; Bonardi A.; Bua S.; Angeli A.; Ferraroni M.; Nocentini A.; Casnati A.; Gratteri P.; Sansone F.; Supuran C.T.
Carbonic anhydrase I, II, IV and IX inhibition with a series of 7-amino-3,4-dihydroquinolin-2(1H)-one derivatives
2017 Bozdag, Murat; Bua, Silvia; Osman, Sameh M; AlOthman, Zeid; Supuran, Claudiu T
Carbonic Anhydrase Inhibition Activities of Schiff’s Bases Based on Quinazoline-Linked Benzenesulfonamide
2022 El-Azab, Adel S.; Abdel-Aziz, Alaa A.-M.; Ghabbour, Hazem A.; Bua, Silvia; Nocentini, Alessio; Alkahtani, Hamad M.; Alsaif, Nawaf A.; Al-Agamy, Mohamed H. M.; Supuran, Claudiu T.
Carbonic anhydrase inhibitors as diuretics
2019 Bua S.; Nocentini A.; Supuran C.T.
Carbonic anhydrase inhibitors based on sorafenib scaffold: Design, synthesis, crystallographic investigation and effects on primary breast cancer cells
2019 Bozdag, Murat; Ferraroni, Marta; Ward, Carol; Carta, Fabrizio; Bua, Silvia; Angeli, Andrea; Langdon, Simon P; Kunkler, Ian H; Al-Tamimi, Abdul-Malek S; Supuran, Claudiu T