LENCI, ELENA
 Distribuzione geografica
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Continente #
NA - Nord America 4.623
EU - Europa 3.202
AS - Asia 2.700
SA - Sud America 315
Continente sconosciuto - Info sul continente non disponibili 130
AF - Africa 49
OC - Oceania 42
Totale 11.061
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Nazione #
US - Stati Uniti d'America 4.507
RU - Federazione Russa 941
IT - Italia 909
CN - Cina 792
SG - Singapore 731
PL - Polonia 419
HK - Hong Kong 326
BR - Brasile 248
KR - Corea 229
VN - Vietnam 202
IE - Irlanda 189
BD - Bangladesh 138
SE - Svezia 111
FI - Finlandia 102
FR - Francia 91
AT - Austria 87
DE - Germania 82
IN - India 82
NL - Olanda 82
GB - Regno Unito 77
CA - Canada 65
JP - Giappone 47
AU - Australia 36
ID - Indonesia 33
ES - Italia 32
JO - Giordania 30
MX - Messico 25
AR - Argentina 21
IQ - Iraq 17
NG - Nigeria 15
EC - Ecuador 14
BE - Belgio 11
CH - Svizzera 11
UA - Ucraina 10
JM - Giamaica 9
TR - Turchia 9
CI - Costa d'Avorio 8
CL - Cile 8
CO - Colombia 8
NP - Nepal 8
EE - Estonia 7
MA - Marocco 7
RO - Romania 7
ZA - Sudafrica 7
NZ - Nuova Zelanda 6
SA - Arabia Saudita 6
TH - Thailandia 6
VE - Venezuela 6
MY - Malesia 5
RS - Serbia 5
AE - Emirati Arabi Uniti 4
BY - Bielorussia 4
DK - Danimarca 4
GE - Georgia 4
IL - Israele 4
KZ - Kazakistan 4
PK - Pakistan 4
PR - Porto Rico 4
TW - Taiwan 4
BG - Bulgaria 3
CZ - Repubblica Ceca 3
DZ - Algeria 3
HN - Honduras 3
KE - Kenya 3
LI - Liechtenstein 3
PH - Filippine 3
PY - Paraguay 3
AZ - Azerbaigian 2
BJ - Benin 2
BO - Bolivia 2
CR - Costa Rica 2
DO - Repubblica Dominicana 2
EG - Egitto 2
KG - Kirghizistan 2
LB - Libano 2
LT - Lituania 2
LV - Lettonia 2
MD - Moldavia 2
NI - Nicaragua 2
PE - Perù 2
PT - Portogallo 2
UY - Uruguay 2
AF - Afghanistan, Repubblica islamica di 1
GR - Grecia 1
GY - Guiana 1
HU - Ungheria 1
KW - Kuwait 1
NO - Norvegia 1
PA - Panama 1
PS - Palestinian Territory 1
QA - Qatar 1
SK - Slovacchia (Repubblica Slovacca) 1
SN - Senegal 1
SV - El Salvador 1
SY - Repubblica araba siriana 1
TN - Tunisia 1
TT - Trinidad e Tobago 1
UZ - Uzbekistan 1
VC - Saint Vincent e Grenadine 1
Totale 10.931
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Città #
Santa Clara 1.166
Ashburn 635
Singapore 533
Warsaw 417
Fairfield 287
Hong Kong 282
Seoul 215
Florence 209
Hefei 201
Dublin 187
San Jose 163
Chandler 155
Beijing 137
Dallas 127
Seattle 123
Woodbridge 123
Milan 119
Council Bluffs 107
Houston 99
Los Angeles 95
Cambridge 87
Moscow 86
Vienna 83
Wilmington 81
Helsinki 66
Ho Chi Minh City 65
Altamura 63
Lawrence 61
Lauterbourg 54
Ann Arbor 47
Buffalo 47
Rome 47
The Dalles 45
Hanoi 44
Princeton 41
Kent 40
Mumbai 39
New York 38
Tokyo 36
Amsterdam 35
Shanghai 35
Boston 33
São Paulo 33
Melbourne 30
San Diego 27
Jakarta 26
Naples 26
Chicago 20
Lappeenranta 20
Bologna 19
Guangzhou 19
Medford 19
Clifton 18
Utrecht 18
Toronto 17
Dong Ket 16
Phoenix 16
Abuja 15
Turin 15
Munich 14
Orem 13
Arezzo 12
Salt Lake City 12
Boardman 11
Brooklyn 11
Falls Church 11
Haiphong 11
London 11
Norwalk 11
Brussels 10
Montreal 10
Paris 9
Perugia 9
Stockholm 9
Abidjan 8
Atlanta 8
Barcelona 8
Bari 8
Brasília 8
Frankfurt am Main 8
Handan 8
Nanjing 8
Poplar 8
Yubileyny 8
Bengaluru 7
Cagliari 7
Genoa 7
Madrid 7
Redondo Beach 7
Rio de Janeiro 7
Tianjin 7
Turku 7
Verona 7
Alexandria 6
Andover 6
Bern 6
Chennai 6
Denver 6
Dhaka 6
Falkenstein 6
Totale 7.256
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Nome #
Diversity-Oriented Synthesis of novel glyco- and peptidomimetic scaffolds 375
Identification of novel human breast carcinoma (MDA-MB-231) Cell growth modulators from a carbohydrate-based diversity oriented synthesis library 358
Diversity-Oriented Synthesis and Chemoinformatic Analysis of the Molecular Diversity of sp3-Rich Morpholine Peptidomimetics 273
Design and synthesis of bicyclic acetals as Beta Secretase (BACE1) inhibitors 236
AI is a viable alternative to high throughput screening: a 318-target study 231
Peptidomimetic toolbox for drug discovery 226
Carbohydrates in diversity-oriented synthesis: Challenges and opportunities 222
Non-dioxin-like organic toxicant PCB153 modulates sphingolipid metabolism in liver progenitor cells: its role in Cx43-formed gap junction impairment 217
Ceramide/protein phosphatase 2A axis is engaged in gap junction impairment elicited by PCB153 in liver stem-like progenitor cells 215
Exploring the chemical space and the bioactivity profile of lactams: A chemoinformatic study 212
Copper-Catalyzed A3-Coupling for the Diversity-Oriented Synthesis of Proline-Derived Alkynyl-Substituted Peptidomimetic Scaffolds 210
Development of a GC-376 Based Peptidomimetic PROTAC as a Degrader of 3-Chymotrypsin-like Protease of SARS-CoV-2 195
A Structural Investigation of the Interaction between a GC-376-Based Peptidomimetic PROTAC and Its Precursor with the Viral Main Protease of Coxsackievirus B3 190
Bicyclic acetals: Biological relevance, scaffold analysis, and applications in diversity-oriented synthesis 188
A glucose-derived α-hydroxy aldehyde for the Petasis reaction: facile access to polyfunctional δ-amino acids 188
Combination of multicomponent KA2 and Pauson-Khand reactions: Short synthesis of spirocyclic pyrrolocyclopentenones 187
Identification of highly potent and selective MMP2 inhibitors addressing the S1′ subsite with D-proline-based compounds 187
Synthesis and Chemoinformatic Analysis of Fluorinated Piperidines as 3D Fragments for Fragment-Based Drug Discovery 182
Design, synthesis and evaluation of RGD peptidomimetic – Gold nanostar conjugates as M21 cell adhesion inhibitors 182
Two-step one-pot synthesis of dihydropyrazinones as Xaa-Ser dipeptide isosteres through morpholine acetal rearrangement 180
Click Chemistry for advancing the development of dual RGD integrin/MMP ligands. 179
Design and Synthesis of Novel Raman Reporters for Bioorthogonal SERS Nanoprobes Engineering 178
Nanostars—decorated microfluidic sensors for surface enhanced Raman scattering targeting of biomolecules 178
Probing bioactive motifs through C(sp3)-H activation for the development of protease inhibitors 176
Skeletal Diversity from Carbohydrates: Use of Mannose for the Diversity-Oriented Synthesis of Polyhydroxylated Compounds 176
Tyrosine-derived Peptidomimetics as Dual Gelatinase Inhibitors and Integrin Ligands 174
Identification of a short ACE2-derived stapled peptide targeting the SARS-CoV-2 spike protein 174
Diversity-Oriented Synthesis as a Tool for Chemical Genetics 174
Short synthesis of polyfunctional sp3-rich threonine-derived morpholine scaffolds 174
Design of dual peptidomimetic gelatinase/integrin inhibitors for tumor angiogenesis targeting 173
3D printing of multifunctional optofluidic systems for high-sensitive detection of pathological biomarkers in liquid biopsies 173
Occurrence of morpholine in central nervous system drug discovery 173
Recent advances in copper-catalyzed imine-based multicomponent reactions 172
Peptidomimetic Small-Molecule Inhibitors of 3CLPro Activity and Spike-ACE2 Interaction: Toward Dual-Action Molecules against Coronavirus Infections 168
Diversity-oriented synthesis as a tool to expand the chemical space of DNA-encoded libraries 167
Small Molecule Drug Discovery: Methods, Molecules and Applications 167
Development of new peptidomimetic NADPH oxidase inhibitors with antithrombotic properties 166
Citrate-capped gold nanoparticles as colorimetric sensors for amyloid ßpeptide (1-42) targeting in liquid samples 165
Occurrence of the d-proline chemotype in enzyme inhibitors 165
Insight to the binding mode of triazole RGD-peptidomimetics to integrin-rich cancer cells by NMR and molecular modeling 164
Computational-aided design of a library of lactams through a Diversity-Oriented Synthesis strategy 160
Multitargeting application of proline-derived peptidomimetics addressing cancer-related human matrix metalloproteinase 9 and carbonic anhydrase II 158
Synthesis of morpholine derivatives using the Castagnoli-Cushman reaction as BACE1 inhibitors: Unexpected binding activity of cyclic thioamides 156
Smart Design of Small-Molecule Libraries: When Organic Synthesis Meets Cheminformatics 154
Small-molecule RNA ligands: a patent review (2018-2024) 152
Identification of BACE-1 inhibitors through directed C(sp3)-H activation on 5-oxo-pyrrolidine-3-carboxylic acid derivatives 148
Discovery of a d-pro-lys peptidomimetic inhibitor of MMP9: Addressing the gelatinase selectivity beyond S1' subsite 147
Novel matrix metalloproteinase inhibitors: an updated patent review (2014 - 2020) 147
Diversity-oriented synthesis and chemoinformatics: a fruitful synergy towards better chemical libraries 144
Application of the PROTAC-based approach to trigger proteolysis of the Coxsackievirus B3 main protease 140
PROTAC-based approach to develop broad-spectrum antiviral agents triggering the proteolysis of the major viral protease 138
Modular synthesis of 2,4-diaminoanilines as CNS drug-like non-covalent inhibitors of asparagine endopeptidase 137
Oxime Linked Doxorubicin Glycoconjugates Improve the Specific Targeting of Glioblastoma in High-Grade Glioma Therapy 131
Identification of a Common Pharmacophore for Binding to MMP2 and RGD Integrin: Towards a Multitarget Approach to Inhibit Cancer Angiogenesis and Metastasis 126
Multilayered Bioorthogonal SERS Nanoprobes Selectively Aggregating in Human Fluids: A Smart Optical Assay for β-Amyloid Peptide Quantification 126
Matrix metalloproteases 118
Iridium-catalyzed reductive strecker reaction for late-stage amide and lactam cyanation 107
PROTAC-based approach to develop broad-spectrum antiviral agents triggering the proteolysis of the major viral protease 102
Synthetic approaches toward small molecule libraries 97
An antiviral agent triggering the proteolysis of the main protease from Coxsackievirus B3 96
Synthesis and biological properties of spiroacetal-containing small molecules 96
PROTAC-based approach to develop broad-spectrum antiviral agents triggering the proteolysis of the major viral protease 85
Molecular View on the iRGD Peptide Binding Mechanism: Implications for Integrin Activity and Selectivity Profiles 81
PROTAC-based approach to develop broad-spectrum antiviral agents triggering the proteolysis of the major viral protease 80
PROTAC-based approach to develop broad-spectrum antiviral agents triggering the proteolysis of the major viral protease 65
Exploration of PROTAC technology for the development of broad-spectrum antiviral drugs to trigger the proteolysis of the main viral protease 63
Evaluation of in vitro antiviral activity against different SARS-CoV-2 variants of a protease PROTAC degrader 17
Totale 11.061
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Categoria #
all - tutte 30.169
article - articoli 0
book - libri 0
conference - conferenze 0
curatela - curatele 0
other - altro 0
patent - brevetti 0
selected - selezionate 0
volume - volumi 0
Totale 30.169
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Totale Lug Ago Sett Ott Nov Dic Gen Feb Mar Apr Mag Giu
2021/2022246 0 11 11 4 13 21 8 29 17 25 19 88
2022/2023896 68 154 62 62 92 152 100 73 70 6 43 14
2023/2024544 14 38 43 34 43 78 24 88 39 68 42 33
2024/20253.074 93 276 144 406 874 576 78 167 134 68 101 157
2025/20264.411 390 498 634 343 466 191 461 214 283 255 214 462
2026/2027229 137 92 0 0 0 0 0 0 0 0 0 0
Totale 11.061