BRUNI, FABRIZIO
 Distribuzione geografica
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Continente #
NA - Nord America 4.811
EU - Europa 2.902
AS - Asia 2.342
SA - Sud America 218
AF - Africa 62
Continente sconosciuto - Info sul continente non disponibili 58
OC - Oceania 30
Totale 10.423
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Nazione #
US - Stati Uniti d'America 4.722
RU - Federazione Russa 1.032
HK - Hong Kong 791
SG - Singapore 598
IT - Italia 539
CN - Cina 453
PL - Polonia 275
IE - Irlanda 242
SE - Svezia 219
BR - Brasile 173
UA - Ucraina 170
VN - Vietnam 153
KR - Corea 145
DE - Germania 135
GB - Regno Unito 103
FR - Francia 88
CA - Canada 67
FI - Finlandia 63
IN - India 54
AU - Australia 30
TR - Turchia 25
JO - Giordania 22
JP - Giappone 18
AR - Argentina 16
BD - Bangladesh 16
ID - Indonesia 13
CI - Costa d'Avorio 12
SC - Seychelles 12
IQ - Iraq 10
VE - Venezuela 9
MA - Marocco 8
MX - Messico 8
NG - Nigeria 8
NL - Olanda 8
BE - Belgio 7
CO - Colombia 7
PK - Pakistan 7
EC - Ecuador 6
KE - Kenya 6
MY - Malesia 6
TH - Thailandia 5
TN - Tunisia 5
ZA - Sudafrica 5
AE - Emirati Arabi Uniti 4
ES - Italia 4
PH - Filippine 4
CH - Svizzera 3
EG - Egitto 3
HN - Honduras 3
TW - Taiwan 3
UZ - Uzbekistan 3
AL - Albania 2
AM - Armenia 2
CL - Cile 2
CR - Costa Rica 2
LT - Lituania 2
NI - Nicaragua 2
NO - Norvegia 2
PE - Perù 2
PY - Paraguay 2
AF - Afghanistan, Repubblica islamica di 1
AZ - Azerbaigian 1
BB - Barbados 1
BG - Bulgaria 1
CY - Cipro 1
CZ - Repubblica Ceca 1
DK - Danimarca 1
DO - Repubblica Dominicana 1
DZ - Algeria 1
EU - Europa 1
GP - Guadalupe 1
GR - Grecia 1
HU - Ungheria 1
IL - Israele 1
JM - Giamaica 1
KG - Kirghizistan 1
MU - Mauritius 1
NP - Nepal 1
PA - Panama 1
PS - Palestinian Territory 1
PT - Portogallo 1
QA - Qatar 1
RO - Romania 1
SA - Arabia Saudita 1
SI - Slovenia 1
SY - Repubblica araba siriana 1
TT - Trinidad e Tobago 1
TZ - Tanzania 1
UY - Uruguay 1
VG - Isole Vergini Britanniche 1
XK - ???statistics.table.value.countryCode.XK??? 1
Totale 10.367
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Città #
Santa Clara 1.115
Hong Kong 739
Singapore 434
Ashburn 395
Fairfield 368
Warsaw 275
Chandler 251
Dublin 241
Jacksonville 235
Woodbridge 158
San Jose 153
Buffalo 144
Seoul 144
Seattle 143
Houston 136
Cambridge 115
Wilmington 109
Los Angeles 104
Milan 103
Beijing 101
Hefei 89
Council Bluffs 80
Altamura 77
Ann Arbor 68
Lawrence 68
Dallas 63
Princeton 61
Lauterbourg 54
Ho Chi Minh City 48
Rome 46
The Dalles 43
Hanoi 40
Medford 40
Boardman 39
San Diego 30
Melbourne 29
Moscow 29
Boston 28
Florence 28
Shanghai 27
Mumbai 25
Munich 24
Ottawa 24
Naples 19
Paris 19
Clifton 18
Tokyo 17
Izmir 16
New York 16
São Paulo 16
Turin 15
Bologna 14
Kent 14
West Jordan 14
Abidjan 12
Chennai 12
Norwalk 12
Orem 12
Philadelphia 11
Figino 10
Frankfurt Am Main 10
Chicago 9
Columbus 9
Helsinki 9
Abuja 8
Guangzhou 8
Miano 8
Montreal 8
Phoenix 8
Redondo Beach 8
Turku 8
Yubileyny 8
Brussels 7
Falls Church 7
Frankfurt am Main 7
Haiphong 7
Palermo 7
Bari 6
Casablanca 6
Da Nang 6
Denver 6
Rio de Janeiro 6
Verona 6
Fortaleza 5
Genoa 5
Manchester 5
Nairobi 5
Newmarket 5
Shenzhen 5
Tianjin 5
Toronto 5
Amsterdam 4
Auburn Hills 4
Bergamo 4
Brasília 4
Dhaka 4
Dong Ket 4
Hillsboro 4
Istanbul 4
Jakarta 4
Totale 7.018
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Nome #
New fluoro derivatives of the pyrazolo[5,1-c][1,2,4]benzotriazine 5-oxide system: evaluation of fluorine binding properties in the benzodiazepine site on gamma-aminobutyrric acid type A (GABAA) receptor. Design, synthesis, biological evaluation, and molecular modeling investigation. 277
Development of ligands at gamma aminobutyrric acid type A (GABAA) receptor subtype as new agent for pain relief. 269
New 3-, 8-disubstituted pyrazolo[5,1-c][1,2,4]benzotriazines useful for studying the interaction with the HBp-3 area (hydrogen bond point area) in the benzodiazepine site on the gamma-aminobutyric acid type A (GABAA) receptor 261
Novel 3-iodo-8-ethoxypyrazolo[5,1-c][1,2,4]benzotriazine 5-oxide as promising lead for design of alpha5-inverse agonist, useful tools for therapy of mnemonic damage. 254
1H and 13C NMR Study of the Pyrazolo[1,5-a]pyrimidine System 238
8H-PYRAZOLO[5',1':2,3]PYRIMIDO[5,4-D][1,2]DIAZEPINE. A NEW TRICYCLIC SYSTEM. 220
Pyrazolo[1,5-a]pyrido[3,4-e]pyrimidin-6-ones. II. Synthesis and in vitro antimicrobial evaluation 216
BENZODIAZEPINE RECEPTOR LIGANDS. 7. SYNTHESIS AND PHARMACOLOGICAL EVALUATION OF NEW 3-ESTERS OF THE 8-CHLOROPYRAZOLO[5,1-C][1,2,4]BENZOTRIAZINE 5-OXIDE. 3-(2- THIENYLMETHOXYCARBONYL) DERIVATIVE: AN ANXIOSELECTIVE AGENT IN RODENTS. 215
2-Arylpyrazolo[1,5-a]pyrimidin-3-yl acetamides. New potent and selective Peripheral Benzodiazepine Receptor ligands 208
BENZODIAZEPINE RECEPTOR LIGANDS. SYNTHESIS AND PHARMACOLOGICAL EVALUATION OF 3-, 7- AND 8-SUBSTITUTED [5,1-C][1,2,4]BENZOTRIAZINES AND 5-OXIDE DERIVATIVES. PART I. 207
Benzodiazepine receptor ligands. 8. Synthesis and pharamcological evaluation of new pyrazolo[5,1-c][1,2,4]benzotriazine 5-oxide 3- and 8-disubstituted: high affinity ligands endowed with inverse-agonist pharmacological efficacy. 204
Synthesis, in vivo evaluation, and molecular modeling studies of new pyrazolo[5,1-c][1,2,4]benzotriazine 5-oxide derivatives. Identification of a bifunctional hydrogen bond area related to the inverse-agonism 204
CHEMISTRY OF SUBSTITUTED PYRAZOLO[1,5-A]PYRIMIDINES PART 4. A STRUCTURAL CORRECTION OF A SERIES OF PYRAZOLO[5',1':2,3]PYRIMIDO[5,4-D][1,2]DIAZEPINES ON THE BASIS OF NMR SPECTROSCOPY AND X-RAY DIFFRACTION ANALYSIS . 199
Synthesis and Benzodiazepine Receptor Affinity of Pyrazolo [1,5-a]pyrimidine Derivatives.3. New 6-(3-Thienyl) Series as a1 Selective Ligands 199
A New Entry to Pyrazolo[1,5-a]pyrido[3,4-e]pyrimidine Derivatives 197
Benzodiazepine receptor ligands. 4. Synthesis and pharmacological evaluation of 3-heteroaryl-8-chloropyrazolo[5,1-c][1,2,4]benzotriazine 5- oxides 191
SYNTHESIS AND STUDY OF THE ANTIINFLAMMATORY PROPERTIES OF SOME PYRAZOLO[1,5-A]PYRIMIDINE DERIVATIVES. 189
A novel selective GABA-A alpha1 receptor agonist displaying sedative and anxiolytic-like properties in rodents. 189
BENZODIAZEPINE RECEPTOR (BZR) LIGANDS.5. NEW 3-ALKYLOXYCARBONYL-, 3-CYCLOALKYLOXYCARBONYL-,3-ARYLOXYCARBONYLDERIVATIVES OF PYRAZOLO [5,1-C][1,2,4]BENZOTRIAZINE 5-OXIDES: A STUDY ON THE 3-ESTER FUNCTION MODIFICATION 177
SYNTHESIS OF 7-(2-DIMETHYLAMINOVINYL) DERIVATIVES OF PYRAZOLO[1,5-A]PYRIMIDINES, AS PRECURSOR OF NEW TRICYCLIC SERIES. BINDING STUDIES OF BDZ RECEPTOR. 176
Benzodiazepine receptor ligands - Part II. Synthesis and biological evaluation of pyrazolo[5,1-c][1,2,4]benzotriazine 4-oxide 176
8H-pyrazolo[5′,1′:2,3]pyrimido[5,4-d][1,2]diazepine: A new tricyclic system 176
Pyrazolo[1,5-a]pyrido[3,4-e]pyrimidine: a New Heterocyclic Ring System 175
CHEMISTRY OF SUBSTITUTED PYRAZOLO[1,5-A]PYRIMIDINES. PART 3. A LITERATURE CORRECTION ON THE BASIS OF 13C NMR SPECTROSCOPY. 172
REACTIVITY OF 7-(2-DIMETHYLAMINOVINYL) PYRAZOLO[1,5-A]PYRIMIDINES: SYNTHESIS OF PYRAZOLO[1,5-A]PYRIDO[3,4-E]PYRIMIDINE DERIVATIVES AS POTENTIAL BENZODIAZEPINE RECEPTOR LIGANDS.1 168
PYRAZOLO[1,5-A]PYRIDO[3,4-E]PYRIMIDN-6-ONES. II. SYNTHESIS AND IN VITRO ANTIMICROBIAL EVALUATION. 165
Antiproliferative and antimicrobial activities of pyrazolo[5,1-c][1,2,4]benzotriazines 5-oxides and their 5-deoxyderivatives. 162
SYNTHESIS, BENZODIAZEPINE RECEPTOR AFFINITY AND ANTICONVULSANT ACTIVITY OF 3-ARYL-4,7-DIHYDRO-6-(N1'-ALKYLPYRAZOL-3' OR 5'-YL)PYRAZOLO[1,5-A]PYRIMIDIN-7-ONES 158
Synthesis and study of the anti‐inflammatory properties of some pyrazolo[1,5‐a]pyrimidine derivatives 158
Synthesis, Benzodiazepine receptor affinity of pyrazolo[1,5-a]pyrimidine derivatives. Study of the structural features for BZR recognition- Part I. 158
Synthesis and BZR affinity of pyrazolo[1,5-a]pyrimidine derivatives. Part 1: Study of the structural features for BZR recognition 158
Benzodiazepine receptor ligands. 6. New 3-(2-,3- or 4-substituted benzyloxycarbonyl) derivatives of 8-chloropyrazolo[5,1-c][1,2,4]benzotriazine 5-oxide receptor affinity and In vivo testing C. Martini, P. Malmberg Aiello 157
Benzodiazepine receptor ligands III. Synthesis and biological evaluation of 2- and/or 3-substituted pyrazolo[5,1-c][1,2,4]benzotriazine 5-oxides 157
Benzodiazepine receptor ligands. 4.Synthesis, and pharmacological evaluation of 3-hetroaryl-8-chloro pyrazolo[5,1-c][1,2,4] benzotriazine 5-oxides. 156
Insight into 2-phenylpyrazolo[1,5-a]pyrimidin-3-yl acetamides as Peripheral Benzodiazepine Receptor Ligands: synthesis, biological evaluation and 3D-QSAR investigation. 156
Antiproliferative and antimicrobial activities of pyrazolo[5,1- c][1,2,4]benzotriazine 5-oxides and their 5-deoxyderivatives 155
Unambiguous Structure Determination of Some Pyrazolo[1,5-a]pyrimidine Deri-vatives by Multinuclear NMR Spectroscopy 154
Benzodiazepine receptor ligands. Part III. Synthesis and biological evaluation of 2 and/or 3-substituted pyrazolo[5,1-c][1,2,4] benzotriazine 5-oxides. 148
REACTIVITY OF 7-(2-DIMETHYLAMINOVINYL)PYRAZOLO[1,5-A]PYRIMIDINES: SYNTHESIS OF PYRAZOLO[1,5-A]PYRIDO[3,4-E]PYRIMIDINE DERIVATIVES AS POTENTIAL BENZODIAZEPINE RECEPTOR LIGANDS. 2. 148
BENZODIAZEPINE RECEPTOR LIGANDS. PART II. SYNTHESIS AND BIOLOGICAL EVALUATION OF PYRAZOLO[5,1-C][1,2,4]BENZOTRIAZINES 4-OXIDE. 147
Synthesis and pharmacological evaluation of 3-(2-furyl)- and 3-(3-furyl)-(-chloropyrazolo[5,1-c][1,2,4]benzotriazine 5-oxides, new 3-heteroaryl substituted benzodiazepine receptor ligands. 146
Synthesis and preliminary evaluation of pyrazolo[1,5-a]pyrido[3,4-e]pyrimidin-6(7H)ones and related compounds, as benzodiazepine receptor ligands and anticonvulsant agents. 143
Novel 3-aroylpyrazolo[5,1-c][1,2,4] benzotriazines 5-oxides 8-substituted, ligands at GABAA/benzodiazepine receptor complex: synthesis, pharmacological and molecular modelling studies. 141
Reactivity of 7‐(2‐dimethylaminovinyl)pyrazolo[1,5‐a]pyrimidines: Synthesis of pyrazolo[1,5‐a]pyrido[3,4‐e]pyrimidine derivatives as potential benzodiazepine receptor ligands. 2 141
ChemInform Abstract: Pyrazolo(1,5‐a)pyrido(3,4‐e)pyrimidin‐6‐ones. Part 1. Synthesis and in vitro Antimicrobial Evaluation 140
Chemistry of Substituted Pyrazolo[1,5-a]pyrimidines. Part 5. 7-Oxo-6-[bpyrazol-3’(5’)-yl]-4,7-dihydropyrazolo[1,5-a]pyrimidines from 6-Ethoxycarbonyl-7-(2-dimethylaminovinyl)-pyrazolo[1,5-a]pyrimidines: Elucidation of the Reaction Mechanism through NMR Spectroscopy and X-Ray Diffraction Analysis 140
Unambiguous structure determination of some pyrazolo [1,5‐a]pyrimidine derivatives by multinuclear NMR spectroscopy 140
PYRAZOLO[1,5-A]PYRIDO[3,4-E]PYRIMIDIN-6-ONES. I. SYNTHESIS AND IN VITRO ANTIMICROBIAL AND ANTIFUNGAL EVALUATION. 136
Synthesis of CNS Potentially Active Bicyclic and Tricyclic Derivatives of Pyrazolo[1,5-a][1,3] diazepines. 135
Reactivity of 7‐(2‐dimethylaminovinyl)pyrazolo[1,5‐a]pyrimidines: Synthesis of pyrazolo[1,5‐a]pyrido[3,4‐e]pyrimidine derivatives as potential benzodiazepine receptor ligands. 1 131
ChemiInform Abstract: reactivity of 7-(2-dimethylaminovinyl)pyrazolo[1,5-a]pyrimidines: synthesis of pyrazolo[1,5-a]pyrido[3,4-e]pyrimidine derivatives as potential benzodiazepine receptor ligands. Part 2 128
NEW 2,3-SUBSTITUTED 4,7-DIHYDRO-6-(1'HPYRAZOL-3'-YL)PYRAZOLO[1,5-A]PYRIMIDI-7-ONES AND RELATED COMPOUNDS: SYNTHESIS AND BENZODIAZEPINE RECEPTOR BINDING STUDY. 125
Synthesis and BZR affinity of pyrazolo [ 1,5-a ] pyrimidine derivatives. Part 2:Further Investigation on the 3-aryl substituents. 124
Reactivity of 1‐(2‐nitrophenyl)‐5‐aminopyrazoles under basic conditions and synthesis of new 3‐, 7‐, and 8‐substituted pyrazolo[5,1‐c][1,2,4]benzotriazine 5‐oxides, as benzodiazepine receptor ligands 124
Synthesis of derivatives of pyrazolo[1,5-a]pyrrolo[1,2-c] [1,3,6]benzotriazocine. 112
Synthesis of derivatives of pyrazolo[1,5-α]pyrrolo[1,2-c][1,3,6]-benzotriazocine, a new class of compounds with potential cns activity 110
REACTIVITY OF 1-(2-NITROFENIL)-5-AMINOPYRAZOLES UNDER BASIC CONDITIONS AND SYNTHESIS OF NEW 3-, 7-, AND 8-SUBSTITUTED PYRAZOLO[5,1-C][1,2,4]BENZOTRIAZINE 5-OXIDES, AS BENZODIAZEPINE RECEPTOR LIGANDS.JOURNAL OF HETEROCYCLIC CHEMISTRY , - A. COSTANZO, G. GUERRINI, F. BRUNI, S. SELLERI 109
Synthesis of 3-(1,3,4-thiadiazol-2-yl)pyrazolo[1,5-a]pyrimidine derivatives as potential antimicrobial agents. 106
Pyrazolo[1,5-a]pyrido[3,4-e]pyrimidin-6-ones. I. Synthesis and in vitro antimicrobial evaluation 105
Synthesis of 7-(2-dimethylaminovinyl) derivatives of pyrazolo[1,5-a]pyrimidines, as precursors of new tricyclic series. Binding studies of BDZ receptor 104
Chemistry of Substituted Pyrazolo[1,5-a]pyrimidines. Part 5. 7-Oxo-6-[bpyrazol-3’(5’)-yl]-4,7-dihydropyrazolo[1,5-a]pyrimidines from 6-Ethoxycarbonyl-7-(2-dimethylaminovinyl)-pyrazolo[1,5-a]pyrimidines: Elucidation of the Reaction Mechanism through NMR Spectroscopy and X-Ray Diffraction Analysis 101
REACTIVITY OF 1-(2-NITROFENIL)-5-AMINOPYRAZOLES UNDER BASIC CONDITIONS AND SYNTHESIS OF NEW 3-, 7-, AND 8-SUBSTITUTED PYRAZOLO[5,1-C][1,2,4]BENZOTRIAZINE 5-OXIDES, AS BENZODIAZEPINE RECEPTOR LIGANDS.JOURNAL OF HETEROCYCLIC CHEMISTRY , - A. COSTANZO, G. GUERRINI, F. BRUNI, S. SELLERI 98
Chemistry of substituted pyrazolo[1,5-a]pyrimidines. Part 4.1A Structural Correction of a Series of Pyrazolo[5′,1′:2,3]pyrimido[5,4-d][1,2]diazepines on the basis of NMR spectroscopy and X-ray diffraction analysis 97
ChemInform Abstract: Reactivity of 7‐(2‐Dimethylaminovinyl)pyrazolo(1,5‐a)pyrimidines: Synthesis of Pyrazolo(1,5‐a)pyrido(3,4‐e)pyrimidine Derivatives as Potential Benzodiazepine Receptor Ligands. Part 1 93
Totale 10.423
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Categoria #
all - tutte 28.606
article - articoli 0
book - libri 0
conference - conferenze 0
curatela - curatele 0
other - altro 0
patent - brevetti 0
selected - selezionate 0
volume - volumi 0
Totale 28.606
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Totale Lug Ago Sett Ott Nov Dic Gen Feb Mar Apr Mag Giu
2021/2022382 0 0 26 26 7 14 26 36 16 15 103 113
2022/20231.071 95 216 42 99 91 181 151 56 100 3 25 12
2023/2024334 17 37 64 14 19 55 14 59 1 19 16 19
2024/20253.345 117 284 210 417 914 370 31 336 444 60 95 67
2025/20262.867 356 406 359 114 272 103 337 108 149 165 101 397
2026/2027184 79 87 18 0 0 0 0 0 0 0 0 0
Totale 10.423