BRUNI, FABRIZIO
 Distribuzione geografica
Salva come PNG Salva come JPEG
Continente #
NA - Nord America 2.453
EU - Europa 1.320
AS - Asia 211
AF - Africa 14
Continente sconosciuto - Info sul continente non disponibili 1
SA - Sud America 1
Totale 4.000
Salva come PNG Salva come JPEG
Nazione #
US - Stati Uniti d'America 2.420
PL - Polonia 268
IE - Irlanda 242
SE - Svezia 219
UA - Ucraina 166
IT - Italia 165
HK - Hong Kong 105
DE - Germania 104
GB - Regno Unito 84
FI - Finlandia 46
CN - Cina 41
CA - Canada 33
SG - Singapore 21
JO - Giordania 19
TR - Turchia 16
SC - Seychelles 12
FR - Francia 9
BE - Belgio 7
VN - Vietnam 4
CH - Svizzera 3
IN - India 3
RU - Federazione Russa 3
BR - Brasile 1
CZ - Repubblica Ceca 1
EU - Europa 1
MU - Mauritius 1
MY - Malesia 1
NL - Olanda 1
NO - Norvegia 1
RO - Romania 1
TN - Tunisia 1
TW - Taiwan 1
Totale 4.000
Salva come PNG Salva come JPEG
Città #
Fairfield 368
Warsaw 268
Chandler 251
Dublin 241
Jacksonville 234
Ashburn 163
Woodbridge 158
Seattle 142
Houston 135
Cambridge 115
Wilmington 109
Altamura 77
Ann Arbor 68
Lawrence 68
Buffalo 61
Princeton 61
Hong Kong 54
Medford 40
Boardman 39
San Diego 30
Boston 26
Ottawa 24
Florence 19
Shanghai 18
Izmir 16
Singapore 16
West Jordan 14
Kent 13
Norwalk 12
Frankfurt Am Main 10
New York 10
Philadelphia 10
Milan 9
Brussels 7
Falls Church 7
Beijing 5
Newmarket 5
Verona 5
Auburn Hills 4
Dong Ket 4
Hillsboro 4
Toronto 4
Fuzhou 3
Lappeenranta 3
Los Angeles 3
Nuremberg 3
Salerno 3
Siena 3
Andover 2
Arezzo 2
Bern 2
Bologna 2
Bremen 2
Chiswick 2
Düsseldorf 2
Hounslow 2
Kilburn 2
Redmond 2
Rome 2
Scandicci 2
Tallahassee 2
Trumbull 2
Wandsworth 2
Atlanta 1
Central 1
Chicago 1
Frankfurt am Main 1
Hangzhou 1
Hebei 1
Inveruno 1
Laurel 1
Lausanne 1
Leawood 1
London 1
Mugnano Di Napoli 1
Nenagh 1
New Bedfont 1
Oslo 1
Phoenix 1
Prato 1
Redwood City 1
San Mateo 1
Tunis 1
Wuhan 1
Totale 2.993
Salva come PNG Salva come JPEG
Nome #
Development of ligands at gamma aminobutyrric acid type A (GABAA) receptor subtype as new agent for pain relief. 189
New 3-, 8-disubstituted pyrazolo[5,1-c][1,2,4]benzotriazines useful for studying the interaction with the HBp-3 area (hydrogen bond point area) in the benzodiazepine site on the gamma-aminobutyric acid type A (GABAA) receptor 179
1H and 13C NMR Study of the Pyrazolo[1,5-a]pyrimidine System 121
BENZODIAZEPINE RECEPTOR LIGANDS. 7. SYNTHESIS AND PHARMACOLOGICAL EVALUATION OF NEW 3-ESTERS OF THE 8-CHLOROPYRAZOLO[5,1-C][1,2,4]BENZOTRIAZINE 5-OXIDE. 3-(2- THIENYLMETHOXYCARBONYL) DERIVATIVE: AN ANXIOSELECTIVE AGENT IN RODENTS. 109
BENZODIAZEPINE RECEPTOR LIGANDS. SYNTHESIS AND PHARMACOLOGICAL EVALUATION OF 3-, 7- AND 8-SUBSTITUTED [5,1-C][1,2,4]BENZOTRIAZINES AND 5-OXIDE DERIVATIVES. PART I. 92
Synthesis and Benzodiazepine Receptor Affinity of Pyrazolo [1,5-a]pyrimidine Derivatives.3. New 6-(3-Thienyl) Series as a1 Selective Ligands 91
CHEMISTRY OF SUBSTITUTED PYRAZOLO[1,5-A]PYRIMIDINES PART 4. A STRUCTURAL CORRECTION OF A SERIES OF PYRAZOLO[5',1':2,3]PYRIMIDO[5,4-D][1,2]DIAZEPINES ON THE BASIS OF NMR SPECTROSCOPY AND X-RAY DIFFRACTION ANALYSIS . 89
Synthesis, in vivo evaluation, and molecular modeling studies of new pyrazolo[5,1-c][1,2,4]benzotriazine 5-oxide derivatives. Identification of a bifunctional hydrogen bond area related to the inverse-agonism 88
A New Entry to Pyrazolo[1,5-a]pyrido[3,4-e]pyrimidine Derivatives 86
2-Arylpyrazolo[1,5-a]pyrimidin-3-yl acetamides. New potent and selective Peripheral Benzodiazepine Receptor ligands 86
8H-PYRAZOLO[5',1':2,3]PYRIMIDO[5,4-D][1,2]DIAZEPINE. A NEW TRICYCLIC SYSTEM. 84
REACTIVITY OF 7-(2-DIMETHYLAMINOVINYL) PYRAZOLO[1,5-A]PYRIMIDINES: SYNTHESIS OF PYRAZOLO[1,5-A]PYRIDO[3,4-E]PYRIMIDINE DERIVATIVES AS POTENTIAL BENZODIAZEPINE RECEPTOR LIGANDS.1 83
SYNTHESIS AND STUDY OF THE ANTIINFLAMMATORY PROPERTIES OF SOME PYRAZOLO[1,5-A]PYRIMIDINE DERIVATIVES. 82
Insight into 2-phenylpyrazolo[1,5-a]pyrimidin-3-yl acetamides as Peripheral Benzodiazepine Receptor Ligands: synthesis, biological evaluation and 3D-QSAR investigation. 82
A novel selective GABA-A alpha1 receptor agonist displaying sedative and anxiolytic-like properties in rodents. 81
Benzodiazepine receptor ligands. 8. Synthesis and pharamcological evaluation of new pyrazolo[5,1-c][1,2,4]benzotriazine 5-oxide 3- and 8-disubstituted: high affinity ligands endowed with inverse-agonist pharmacological efficacy. 81
Unambiguous Structure Determination of Some Pyrazolo[1,5-a]pyrimidine Deri-vatives by Multinuclear NMR Spectroscopy 80
Synthesis and preliminary evaluation of pyrazolo[1,5-a]pyrido[3,4-e]pyrimidin-6(7H)ones and related compounds, as benzodiazepine receptor ligands and anticonvulsant agents. 79
Pyrazolo[1,5-a]pyrido[3,4-e]pyrimidine: a New Heterocyclic Ring System 76
Synthesis and study of the anti‐inflammatory properties of some pyrazolo[1,5‐a]pyrimidine derivatives 75
8H-pyrazolo[5′,1′:2,3]pyrimido[5,4-d][1,2]diazepine: A new tricyclic system 75
REACTIVITY OF 7-(2-DIMETHYLAMINOVINYL)PYRAZOLO[1,5-A]PYRIMIDINES: SYNTHESIS OF PYRAZOLO[1,5-A]PYRIDO[3,4-E]PYRIMIDINE DERIVATIVES AS POTENTIAL BENZODIAZEPINE RECEPTOR LIGANDS. 2. 75
SYNTHESIS OF 7-(2-DIMETHYLAMINOVINYL) DERIVATIVES OF PYRAZOLO[1,5-A]PYRIMIDINES, AS PRECURSOR OF NEW TRICYCLIC SERIES. BINDING STUDIES OF BDZ RECEPTOR. 73
Benzodiazepine receptor ligands. 4. Synthesis and pharmacological evaluation of 3-heteroaryl-8-chloropyrazolo[5,1-c][1,2,4]benzotriazine 5- oxides 70
New fluoro derivatives of the pyrazolo[5,1-c][1,2,4]benzotriazine 5-oxide system: evaluation of fluorine binding properties in the benzodiazepine site on gamma-aminobutyrric acid type A (GABAA) receptor. Design, synthesis, biological evaluation, and molecular modeling investigation. 68
Synthesis of CNS Potentially Active Bicyclic and Tricyclic Derivatives of Pyrazolo[1,5-a][1,3] diazepines. 65
Synthesis and BZR affinity of pyrazolo[1,5-a]pyrimidine derivatives. Part 1: Study of the structural features for BZR recognition 65
Synthesis and pharmacological evaluation of 3-(2-furyl)- and 3-(3-furyl)-(-chloropyrazolo[5,1-c][1,2,4]benzotriazine 5-oxides, new 3-heteroaryl substituted benzodiazepine receptor ligands. 64
BENZODIAZEPINE RECEPTOR (BZR) LIGANDS.5. NEW 3-ALKYLOXYCARBONYL-, 3-CYCLOALKYLOXYCARBONYL-,3-ARYLOXYCARBONYLDERIVATIVES OF PYRAZOLO [5,1-C][1,2,4]BENZOTRIAZINE 5-OXIDES: A STUDY ON THE 3-ESTER FUNCTION MODIFICATION 63
Unambiguous structure determination of some pyrazolo [1,5‐a]pyrimidine derivatives by multinuclear NMR spectroscopy 63
Reactivity of 7‐(2‐dimethylaminovinyl)pyrazolo[1,5‐a]pyrimidines: Synthesis of pyrazolo[1,5‐a]pyrido[3,4‐e]pyrimidine derivatives as potential benzodiazepine receptor ligands. 1 61
Benzodiazepine receptor ligands - Part II. Synthesis and biological evaluation of pyrazolo[5,1-c][1,2,4]benzotriazine 4-oxide 61
Reactivity of 1‐(2‐nitrophenyl)‐5‐aminopyrazoles under basic conditions and synthesis of new 3‐, 7‐, and 8‐substituted pyrazolo[5,1‐c][1,2,4]benzotriazine 5‐oxides, as benzodiazepine receptor ligands 61
Antiproliferative and antimicrobial activities of pyrazolo[5,1-c][1,2,4]benzotriazines 5-oxides and their 5-deoxyderivatives. 59
CHEMISTRY OF SUBSTITUTED PYRAZOLO[1,5-A]PYRIMIDINES. PART 3. A LITERATURE CORRECTION ON THE BASIS OF 13C NMR SPECTROSCOPY. 58
PYRAZOLO[1,5-A]PYRIDO[3,4-E]PYRIMIDN-6-ONES. II. SYNTHESIS AND IN VITRO ANTIMICROBIAL EVALUATION. 55
Benzodiazepine receptor ligands III. Synthesis and biological evaluation of 2- and/or 3-substituted pyrazolo[5,1-c][1,2,4]benzotriazine 5-oxides 54
SYNTHESIS, BENZODIAZEPINE RECEPTOR AFFINITY AND ANTICONVULSANT ACTIVITY OF 3-ARYL-4,7-DIHYDRO-6-(N1'-ALKYLPYRAZOL-3' OR 5'-YL)PYRAZOLO[1,5-A]PYRIMIDIN-7-ONES 53
Novel 3-iodo-8-ethoxypyrazolo[5,1-c][1,2,4]benzotriazine 5-oxide as promising lead for design of alpha5-inverse agonist, useful tools for therapy of mnemonic damage. 53
Benzodiazepine receptor ligands. 6. New 3-(2-,3- or 4-substituted benzyloxycarbonyl) derivatives of 8-chloropyrazolo[5,1-c][1,2,4]benzotriazine 5-oxide receptor affinity and In vivo testing C. Martini, P. Malmberg Aiello 53
Reactivity of 7‐(2‐dimethylaminovinyl)pyrazolo[1,5‐a]pyrimidines: Synthesis of pyrazolo[1,5‐a]pyrido[3,4‐e]pyrimidine derivatives as potential benzodiazepine receptor ligands. 2 52
BENZODIAZEPINE RECEPTOR LIGANDS. PART II. SYNTHESIS AND BIOLOGICAL EVALUATION OF PYRAZOLO[5,1-C][1,2,4]BENZOTRIAZINES 4-OXIDE. 52
Benzodiazepine receptor ligands. Part III. Synthesis and biological evaluation of 2 and/or 3-substituted pyrazolo[5,1-c][1,2,4] benzotriazine 5-oxides. 49
PYRAZOLO[1,5-A]PYRIDO[3,4-E]PYRIMIDIN-6-ONES. I. SYNTHESIS AND IN VITRO ANTIMICROBIAL AND ANTIFUNGAL EVALUATION. 49
NEW 2,3-SUBSTITUTED 4,7-DIHYDRO-6-(1'HPYRAZOL-3'-YL)PYRAZOLO[1,5-A]PYRIMIDI-7-ONES AND RELATED COMPOUNDS: SYNTHESIS AND BENZODIAZEPINE RECEPTOR BINDING STUDY. 48
Novel 3-aroylpyrazolo[5,1-c][1,2,4] benzotriazines 5-oxides 8-substituted, ligands at GABAA/benzodiazepine receptor complex: synthesis, pharmacological and molecular modelling studies. 46
Benzodiazepine receptor ligands. 4.Synthesis, and pharmacological evaluation of 3-hetroaryl-8-chloro pyrazolo[5,1-c][1,2,4] benzotriazine 5-oxides. 45
REACTIVITY OF 1-(2-NITROFENIL)-5-AMINOPYRAZOLES UNDER BASIC CONDITIONS AND SYNTHESIS OF NEW 3-, 7-, AND 8-SUBSTITUTED PYRAZOLO[5,1-C][1,2,4]BENZOTRIAZINE 5-OXIDES, AS BENZODIAZEPINE RECEPTOR LIGANDS.JOURNAL OF HETEROCYCLIC CHEMISTRY , - A. COSTANZO, G. GUERRINI, F. BRUNI, S. SELLERI 45
Antiproliferative and antimicrobial activities of pyrazolo[5,1- c][1,2,4]benzotriazine 5-oxides and their 5-deoxyderivatives 43
Synthesis of derivatives of pyrazolo[1,5-a]pyrrolo[1,2-c] [1,3,6]benzotriazocine. 41
Synthesis and BZR affinity of pyrazolo [ 1,5-a ] pyrimidine derivatives. Part 2:Further Investigation on the 3-aryl substituents. 41
Synthesis, Benzodiazepine receptor affinity of pyrazolo[1,5-a]pyrimidine derivatives. Study of the structural features for BZR recognition- Part I. 41
Chemistry of Substituted Pyrazolo[1,5-a]pyrimidines. Part 5. 7-Oxo-6-[bpyrazol-3’(5’)-yl]-4,7-dihydropyrazolo[1,5-a]pyrimidines from 6-Ethoxycarbonyl-7-(2-dimethylaminovinyl)-pyrazolo[1,5-a]pyrimidines: Elucidation of the Reaction Mechanism through NMR Spectroscopy and X-Ray Diffraction Analysis 39
Synthesis of derivatives of pyrazolo[1,5-α]pyrrolo[1,2-c][1,3,6]-benzotriazocine, a new class of compounds with potential cns activity 39
Synthesis of 3-(1,3,4-thiadiazol-2-yl)pyrazolo[1,5-a]pyrimidine derivatives as potential antimicrobial agents. 36
Chemistry of substituted pyrazolo[1,5-a]pyrimidines. Part 4.1A Structural Correction of a Series of Pyrazolo[5′,1′:2,3]pyrimido[5,4-d][1,2]diazepines on the basis of NMR spectroscopy and X-ray diffraction analysis 35
Chemistry of Substituted Pyrazolo[1,5-a]pyrimidines. Part 5. 7-Oxo-6-[bpyrazol-3’(5’)-yl]-4,7-dihydropyrazolo[1,5-a]pyrimidines from 6-Ethoxycarbonyl-7-(2-dimethylaminovinyl)-pyrazolo[1,5-a]pyrimidines: Elucidation of the Reaction Mechanism through NMR Spectroscopy and X-Ray Diffraction Analysis 30
Pyrazolo[1,5-a]pyrido[3,4-e]pyrimidin-6-ones. II. Synthesis and in vitro antimicrobial evaluation 28
ChemInform Abstract: Pyrazolo(1,5‐a)pyrido(3,4‐e)pyrimidin‐6‐ones. Part 1. Synthesis and in vitro Antimicrobial Evaluation 24
REACTIVITY OF 1-(2-NITROFENIL)-5-AMINOPYRAZOLES UNDER BASIC CONDITIONS AND SYNTHESIS OF NEW 3-, 7-, AND 8-SUBSTITUTED PYRAZOLO[5,1-C][1,2,4]BENZOTRIAZINE 5-OXIDES, AS BENZODIAZEPINE RECEPTOR LIGANDS.JOURNAL OF HETEROCYCLIC CHEMISTRY , - A. COSTANZO, G. GUERRINI, F. BRUNI, S. SELLERI 22
Synthesis of 7-(2-dimethylaminovinyl) derivatives of pyrazolo[1,5-a]pyrimidines, as precursors of new tricyclic series. Binding studies of BDZ receptor 22
Pyrazolo[1,5-a]pyrido[3,4-e]pyrimidin-6-ones. I. Synthesis and in vitro antimicrobial evaluation 20
ChemiInform Abstract: reactivity of 7-(2-dimethylaminovinyl)pyrazolo[1,5-a]pyrimidines: synthesis of pyrazolo[1,5-a]pyrido[3,4-e]pyrimidine derivatives as potential benzodiazepine receptor ligands. Part 2 15
ChemInform Abstract: Reactivity of 7‐(2‐Dimethylaminovinyl)pyrazolo(1,5‐a)pyrimidines: Synthesis of Pyrazolo(1,5‐a)pyrido(3,4‐e)pyrimidine Derivatives as Potential Benzodiazepine Receptor Ligands. Part 1 9
Totale 4.053
Salva come PNG Salva come JPEG
Categoria #
all - tutte 12.941
article - articoli 0
book - libri 0
conference - conferenze 0
curatela - curatele 0
other - altro 0
patent - brevetti 0
selected - selezionate 0
volume - volumi 0
Totale 12.941
Salva come PNG Salva come JPEG


Totale Lug Ago Sett Ott Nov Dic Gen Feb Mar Apr Mag Giu
2019/2020950 59 68 10 107 99 147 95 137 93 45 68 22
2020/2021531 48 32 54 54 18 70 13 57 38 69 30 48
2021/2022447 12 53 26 26 7 14 26 36 16 15 103 113
2022/20231.071 95 216 42 99 91 181 151 56 100 3 25 12
2023/2024334 17 37 64 14 19 55 14 59 1 19 16 19
2024/202526 26 0 0 0 0 0 0 0 0 0 0 0
Totale 4.053