BRUNI, FABRIZIO
 Distribuzione geografica
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Continente #
NA - Nord America 4.331
EU - Europa 2.453
AS - Asia 1.975
SA - Sud America 203
AF - Africa 50
OC - Oceania 30
Continente sconosciuto - Info sul continente non disponibili 2
Totale 9.044
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Nazione #
US - Stati Uniti d'America 4.276
RU - Federazione Russa 1.032
HK - Hong Kong 778
SG - Singapore 515
CN - Cina 349
PL - Polonia 274
IE - Irlanda 242
SE - Svezia 219
IT - Italia 173
BR - Brasile 168
UA - Ucraina 168
KR - Corea 144
DE - Germania 135
GB - Regno Unito 97
FI - Finlandia 56
CA - Canada 42
VN - Vietnam 38
IN - India 36
AU - Australia 30
FR - Francia 28
TR - Turchia 24
JO - Giordania 22
AR - Argentina 14
BD - Bangladesh 13
ID - Indonesia 13
CI - Costa d'Avorio 12
SC - Seychelles 12
JP - Giappone 11
MA - Marocco 8
BE - Belgio 7
IQ - Iraq 7
MX - Messico 7
NL - Olanda 6
CO - Colombia 5
EC - Ecuador 5
KE - Kenya 5
PK - Pakistan 5
TN - Tunisia 5
VE - Venezuela 5
ZA - Sudafrica 5
AE - Emirati Arabi Uniti 4
CH - Svizzera 3
ES - Italia 3
TH - Thailandia 3
AM - Armenia 2
CL - Cile 2
HN - Honduras 2
LT - Lituania 2
NO - Norvegia 2
PY - Paraguay 2
UZ - Uzbekistan 2
AF - Afghanistan, Repubblica islamica di 1
AZ - Azerbaigian 1
BG - Bulgaria 1
CR - Costa Rica 1
CY - Cipro 1
CZ - Repubblica Ceca 1
DK - Danimarca 1
DO - Repubblica Dominicana 1
EG - Egitto 1
EU - Europa 1
GR - Grecia 1
HU - Ungheria 1
IL - Israele 1
KG - Kirghizistan 1
MU - Mauritius 1
MY - Malesia 1
NP - Nepal 1
PA - Panama 1
PE - Perù 1
PH - Filippine 1
RO - Romania 1
TW - Taiwan 1
TZ - Tanzania 1
UY - Uruguay 1
VG - Isole Vergini Britanniche 1
XK - ???statistics.table.value.countryCode.XK??? 1
Totale 9.044
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Città #
Santa Clara 1.091
Hong Kong 727
Fairfield 368
Singapore 355
Ashburn 277
Warsaw 274
Chandler 251
Dublin 241
Jacksonville 234
Woodbridge 158
Buffalo 144
Seoul 144
Seattle 143
Houston 136
Cambridge 115
Wilmington 109
Los Angeles 102
Beijing 92
Hefei 89
Altamura 77
San Jose 69
Ann Arbor 68
Lawrence 68
Princeton 61
Dallas 60
Medford 40
Boardman 39
San Diego 30
Melbourne 29
Moscow 29
Boston 28
Munich 24
Ottawa 24
Mumbai 23
Florence 21
Shanghai 21
The Dalles 21
Paris 19
Clifton 18
Izmir 16
São Paulo 16
Ho Chi Minh City 15
Kent 14
West Jordan 14
New York 13
Abidjan 12
Council Bluffs 12
Norwalk 12
Tokyo 11
Frankfurt Am Main 10
Philadelphia 10
Milan 9
Redondo Beach 8
Turku 8
Yubileyny 8
Brussels 7
Falls Church 7
Frankfurt am Main 7
Hanoi 7
Casablanca 6
Chennai 6
Chicago 6
Rio de Janeiro 6
Denver 5
Montreal 5
Newmarket 5
Tianjin 5
Verona 5
Auburn Hills 4
Brasília 4
Dong Ket 4
Fortaleza 4
Guangzhou 4
Hillsboro 4
Jakarta 4
Johannesburg 4
London 4
Makassar 4
Nairobi 4
Nuremberg 4
Pesaro 4
San Francisco 4
Toronto 4
Tunis 4
Amman 3
Atlanta 3
Belo Horizonte 3
Campo Grande 3
Dhaka 3
Fuzhou 3
Goiânia 3
Istanbul 3
Lappeenranta 3
Manaus 3
Phoenix 3
Salerno 3
Secaucus 3
Siena 3
São José 3
Yekaterinburg 3
Totale 6.196
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Nome #
New fluoro derivatives of the pyrazolo[5,1-c][1,2,4]benzotriazine 5-oxide system: evaluation of fluorine binding properties in the benzodiazepine site on gamma-aminobutyrric acid type A (GABAA) receptor. Design, synthesis, biological evaluation, and molecular modeling investigation. 247
Development of ligands at gamma aminobutyrric acid type A (GABAA) receptor subtype as new agent for pain relief. 243
New 3-, 8-disubstituted pyrazolo[5,1-c][1,2,4]benzotriazines useful for studying the interaction with the HBp-3 area (hydrogen bond point area) in the benzodiazepine site on the gamma-aminobutyric acid type A (GABAA) receptor 233
Novel 3-iodo-8-ethoxypyrazolo[5,1-c][1,2,4]benzotriazine 5-oxide as promising lead for design of alpha5-inverse agonist, useful tools for therapy of mnemonic damage. 232
1H and 13C NMR Study of the Pyrazolo[1,5-a]pyrimidine System 220
Pyrazolo[1,5-a]pyrido[3,4-e]pyrimidin-6-ones. II. Synthesis and in vitro antimicrobial evaluation 201
8H-PYRAZOLO[5',1':2,3]PYRIMIDO[5,4-D][1,2]DIAZEPINE. A NEW TRICYCLIC SYSTEM. 192
BENZODIAZEPINE RECEPTOR LIGANDS. 7. SYNTHESIS AND PHARMACOLOGICAL EVALUATION OF NEW 3-ESTERS OF THE 8-CHLOROPYRAZOLO[5,1-C][1,2,4]BENZOTRIAZINE 5-OXIDE. 3-(2- THIENYLMETHOXYCARBONYL) DERIVATIVE: AN ANXIOSELECTIVE AGENT IN RODENTS. 190
BENZODIAZEPINE RECEPTOR LIGANDS. SYNTHESIS AND PHARMACOLOGICAL EVALUATION OF 3-, 7- AND 8-SUBSTITUTED [5,1-C][1,2,4]BENZOTRIAZINES AND 5-OXIDE DERIVATIVES. PART I. 186
Synthesis and Benzodiazepine Receptor Affinity of Pyrazolo [1,5-a]pyrimidine Derivatives.3. New 6-(3-Thienyl) Series as a1 Selective Ligands 183
Benzodiazepine receptor ligands. 8. Synthesis and pharamcological evaluation of new pyrazolo[5,1-c][1,2,4]benzotriazine 5-oxide 3- and 8-disubstituted: high affinity ligands endowed with inverse-agonist pharmacological efficacy. 179
Synthesis, in vivo evaluation, and molecular modeling studies of new pyrazolo[5,1-c][1,2,4]benzotriazine 5-oxide derivatives. Identification of a bifunctional hydrogen bond area related to the inverse-agonism 179
SYNTHESIS AND STUDY OF THE ANTIINFLAMMATORY PROPERTIES OF SOME PYRAZOLO[1,5-A]PYRIMIDINE DERIVATIVES. 175
A New Entry to Pyrazolo[1,5-a]pyrido[3,4-e]pyrimidine Derivatives 170
2-Arylpyrazolo[1,5-a]pyrimidin-3-yl acetamides. New potent and selective Peripheral Benzodiazepine Receptor ligands 170
CHEMISTRY OF SUBSTITUTED PYRAZOLO[1,5-A]PYRIMIDINES PART 4. A STRUCTURAL CORRECTION OF A SERIES OF PYRAZOLO[5',1':2,3]PYRIMIDO[5,4-D][1,2]DIAZEPINES ON THE BASIS OF NMR SPECTROSCOPY AND X-RAY DIFFRACTION ANALYSIS . 168
Benzodiazepine receptor ligands. 4. Synthesis and pharmacological evaluation of 3-heteroaryl-8-chloropyrazolo[5,1-c][1,2,4]benzotriazine 5- oxides 162
A novel selective GABA-A alpha1 receptor agonist displaying sedative and anxiolytic-like properties in rodents. 161
8H-pyrazolo[5′,1′:2,3]pyrimido[5,4-d][1,2]diazepine: A new tricyclic system 156
Pyrazolo[1,5-a]pyrido[3,4-e]pyrimidine: a New Heterocyclic Ring System 155
Benzodiazepine receptor ligands - Part II. Synthesis and biological evaluation of pyrazolo[5,1-c][1,2,4]benzotriazine 4-oxide 153
REACTIVITY OF 7-(2-DIMETHYLAMINOVINYL) PYRAZOLO[1,5-A]PYRIMIDINES: SYNTHESIS OF PYRAZOLO[1,5-A]PYRIDO[3,4-E]PYRIMIDINE DERIVATIVES AS POTENTIAL BENZODIAZEPINE RECEPTOR LIGANDS.1 152
BENZODIAZEPINE RECEPTOR (BZR) LIGANDS.5. NEW 3-ALKYLOXYCARBONYL-, 3-CYCLOALKYLOXYCARBONYL-,3-ARYLOXYCARBONYLDERIVATIVES OF PYRAZOLO [5,1-C][1,2,4]BENZOTRIAZINE 5-OXIDES: A STUDY ON THE 3-ESTER FUNCTION MODIFICATION 151
PYRAZOLO[1,5-A]PYRIDO[3,4-E]PYRIMIDN-6-ONES. II. SYNTHESIS AND IN VITRO ANTIMICROBIAL EVALUATION. 148
Synthesis, Benzodiazepine receptor affinity of pyrazolo[1,5-a]pyrimidine derivatives. Study of the structural features for BZR recognition- Part I. 147
SYNTHESIS OF 7-(2-DIMETHYLAMINOVINYL) DERIVATIVES OF PYRAZOLO[1,5-A]PYRIMIDINES, AS PRECURSOR OF NEW TRICYCLIC SERIES. BINDING STUDIES OF BDZ RECEPTOR. 146
Synthesis and study of the anti‐inflammatory properties of some pyrazolo[1,5‐a]pyrimidine derivatives 145
Unambiguous Structure Determination of Some Pyrazolo[1,5-a]pyrimidine Deri-vatives by Multinuclear NMR Spectroscopy 142
Insight into 2-phenylpyrazolo[1,5-a]pyrimidin-3-yl acetamides as Peripheral Benzodiazepine Receptor Ligands: synthesis, biological evaluation and 3D-QSAR investigation. 141
CHEMISTRY OF SUBSTITUTED PYRAZOLO[1,5-A]PYRIMIDINES. PART 3. A LITERATURE CORRECTION ON THE BASIS OF 13C NMR SPECTROSCOPY. 140
Benzodiazepine receptor ligands. 6. New 3-(2-,3- or 4-substituted benzyloxycarbonyl) derivatives of 8-chloropyrazolo[5,1-c][1,2,4]benzotriazine 5-oxide receptor affinity and In vivo testing C. Martini, P. Malmberg Aiello 139
SYNTHESIS, BENZODIAZEPINE RECEPTOR AFFINITY AND ANTICONVULSANT ACTIVITY OF 3-ARYL-4,7-DIHYDRO-6-(N1'-ALKYLPYRAZOL-3' OR 5'-YL)PYRAZOLO[1,5-A]PYRIMIDIN-7-ONES 137
Antiproliferative and antimicrobial activities of pyrazolo[5,1-c][1,2,4]benzotriazines 5-oxides and their 5-deoxyderivatives. 137
Synthesis and BZR affinity of pyrazolo[1,5-a]pyrimidine derivatives. Part 1: Study of the structural features for BZR recognition 135
Benzodiazepine receptor ligands III. Synthesis and biological evaluation of 2- and/or 3-substituted pyrazolo[5,1-c][1,2,4]benzotriazine 5-oxides 134
REACTIVITY OF 7-(2-DIMETHYLAMINOVINYL)PYRAZOLO[1,5-A]PYRIMIDINES: SYNTHESIS OF PYRAZOLO[1,5-A]PYRIDO[3,4-E]PYRIMIDINE DERIVATIVES AS POTENTIAL BENZODIAZEPINE RECEPTOR LIGANDS. 2. 133
Benzodiazepine receptor ligands. Part III. Synthesis and biological evaluation of 2 and/or 3-substituted pyrazolo[5,1-c][1,2,4] benzotriazine 5-oxides. 130
ChemInform Abstract: Pyrazolo(1,5‐a)pyrido(3,4‐e)pyrimidin‐6‐ones. Part 1. Synthesis and in vitro Antimicrobial Evaluation 129
Benzodiazepine receptor ligands. 4.Synthesis, and pharmacological evaluation of 3-hetroaryl-8-chloro pyrazolo[5,1-c][1,2,4] benzotriazine 5-oxides. 129
Antiproliferative and antimicrobial activities of pyrazolo[5,1- c][1,2,4]benzotriazine 5-oxides and their 5-deoxyderivatives 129
Synthesis and pharmacological evaluation of 3-(2-furyl)- and 3-(3-furyl)-(-chloropyrazolo[5,1-c][1,2,4]benzotriazine 5-oxides, new 3-heteroaryl substituted benzodiazepine receptor ligands. 129
BENZODIAZEPINE RECEPTOR LIGANDS. PART II. SYNTHESIS AND BIOLOGICAL EVALUATION OF PYRAZOLO[5,1-C][1,2,4]BENZOTRIAZINES 4-OXIDE. 128
PYRAZOLO[1,5-A]PYRIDO[3,4-E]PYRIMIDIN-6-ONES. I. SYNTHESIS AND IN VITRO ANTIMICROBIAL AND ANTIFUNGAL EVALUATION. 126
Synthesis and preliminary evaluation of pyrazolo[1,5-a]pyrido[3,4-e]pyrimidin-6(7H)ones and related compounds, as benzodiazepine receptor ligands and anticonvulsant agents. 124
Unambiguous structure determination of some pyrazolo [1,5‐a]pyrimidine derivatives by multinuclear NMR spectroscopy 122
Chemistry of Substituted Pyrazolo[1,5-a]pyrimidines. Part 5. 7-Oxo-6-[bpyrazol-3’(5’)-yl]-4,7-dihydropyrazolo[1,5-a]pyrimidines from 6-Ethoxycarbonyl-7-(2-dimethylaminovinyl)-pyrazolo[1,5-a]pyrimidines: Elucidation of the Reaction Mechanism through NMR Spectroscopy and X-Ray Diffraction Analysis 121
Synthesis of CNS Potentially Active Bicyclic and Tricyclic Derivatives of Pyrazolo[1,5-a][1,3] diazepines. 118
Reactivity of 7‐(2‐dimethylaminovinyl)pyrazolo[1,5‐a]pyrimidines: Synthesis of pyrazolo[1,5‐a]pyrido[3,4‐e]pyrimidine derivatives as potential benzodiazepine receptor ligands. 2 117
Novel 3-aroylpyrazolo[5,1-c][1,2,4] benzotriazines 5-oxides 8-substituted, ligands at GABAA/benzodiazepine receptor complex: synthesis, pharmacological and molecular modelling studies. 116
Reactivity of 7‐(2‐dimethylaminovinyl)pyrazolo[1,5‐a]pyrimidines: Synthesis of pyrazolo[1,5‐a]pyrido[3,4‐e]pyrimidine derivatives as potential benzodiazepine receptor ligands. 1 115
NEW 2,3-SUBSTITUTED 4,7-DIHYDRO-6-(1'HPYRAZOL-3'-YL)PYRAZOLO[1,5-A]PYRIMIDI-7-ONES AND RELATED COMPOUNDS: SYNTHESIS AND BENZODIAZEPINE RECEPTOR BINDING STUDY. 108
ChemiInform Abstract: reactivity of 7-(2-dimethylaminovinyl)pyrazolo[1,5-a]pyrimidines: synthesis of pyrazolo[1,5-a]pyrido[3,4-e]pyrimidine derivatives as potential benzodiazepine receptor ligands. Part 2 106
Reactivity of 1‐(2‐nitrophenyl)‐5‐aminopyrazoles under basic conditions and synthesis of new 3‐, 7‐, and 8‐substituted pyrazolo[5,1‐c][1,2,4]benzotriazine 5‐oxides, as benzodiazepine receptor ligands 106
Synthesis and BZR affinity of pyrazolo [ 1,5-a ] pyrimidine derivatives. Part 2:Further Investigation on the 3-aryl substituents. 104
REACTIVITY OF 1-(2-NITROFENIL)-5-AMINOPYRAZOLES UNDER BASIC CONDITIONS AND SYNTHESIS OF NEW 3-, 7-, AND 8-SUBSTITUTED PYRAZOLO[5,1-C][1,2,4]BENZOTRIAZINE 5-OXIDES, AS BENZODIAZEPINE RECEPTOR LIGANDS.JOURNAL OF HETEROCYCLIC CHEMISTRY , - A. COSTANZO, G. GUERRINI, F. BRUNI, S. SELLERI 99
Synthesis of derivatives of pyrazolo[1,5-a]pyrrolo[1,2-c] [1,3,6]benzotriazocine. 94
Pyrazolo[1,5-a]pyrido[3,4-e]pyrimidin-6-ones. I. Synthesis and in vitro antimicrobial evaluation 94
Synthesis of derivatives of pyrazolo[1,5-α]pyrrolo[1,2-c][1,3,6]-benzotriazocine, a new class of compounds with potential cns activity 94
Chemistry of Substituted Pyrazolo[1,5-a]pyrimidines. Part 5. 7-Oxo-6-[bpyrazol-3’(5’)-yl]-4,7-dihydropyrazolo[1,5-a]pyrimidines from 6-Ethoxycarbonyl-7-(2-dimethylaminovinyl)-pyrazolo[1,5-a]pyrimidines: Elucidation of the Reaction Mechanism through NMR Spectroscopy and X-Ray Diffraction Analysis 86
Synthesis of 3-(1,3,4-thiadiazol-2-yl)pyrazolo[1,5-a]pyrimidine derivatives as potential antimicrobial agents. 82
Synthesis of 7-(2-dimethylaminovinyl) derivatives of pyrazolo[1,5-a]pyrimidines, as precursors of new tricyclic series. Binding studies of BDZ receptor 82
Chemistry of substituted pyrazolo[1,5-a]pyrimidines. Part 4.1A Structural Correction of a Series of Pyrazolo[5′,1′:2,3]pyrimido[5,4-d][1,2]diazepines on the basis of NMR spectroscopy and X-ray diffraction analysis 80
ChemInform Abstract: Reactivity of 7‐(2‐Dimethylaminovinyl)pyrazolo(1,5‐a)pyrimidines: Synthesis of Pyrazolo(1,5‐a)pyrido(3,4‐e)pyrimidine Derivatives as Potential Benzodiazepine Receptor Ligands. Part 1 78
REACTIVITY OF 1-(2-NITROFENIL)-5-AMINOPYRAZOLES UNDER BASIC CONDITIONS AND SYNTHESIS OF NEW 3-, 7-, AND 8-SUBSTITUTED PYRAZOLO[5,1-C][1,2,4]BENZOTRIAZINE 5-OXIDES, AS BENZODIAZEPINE RECEPTOR LIGANDS.JOURNAL OF HETEROCYCLIC CHEMISTRY , - A. COSTANZO, G. GUERRINI, F. BRUNI, S. SELLERI 72
Totale 9.100
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Categoria #
all - tutte 24.649
article - articoli 0
book - libri 0
conference - conferenze 0
curatela - curatele 0
other - altro 0
patent - brevetti 0
selected - selezionate 0
volume - volumi 0
Totale 24.649
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Totale Lug Ago Sett Ott Nov Dic Gen Feb Mar Apr Mag Giu
2020/2021255 0 0 0 0 0 0 13 57 38 69 30 48
2021/2022447 12 53 26 26 7 14 26 36 16 15 103 113
2022/20231.071 95 216 42 99 91 181 151 56 100 3 25 12
2023/2024334 17 37 64 14 19 55 14 59 1 19 16 19
2024/20253.345 117 284 210 417 914 370 31 336 444 60 95 67
2025/20261.728 356 406 359 114 272 103 118 0 0 0 0 0
Totale 9.100