GRATTERI, PAOLA
 Distribuzione geografica
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Continente #
NA - Nord America 13.642
EU - Europa 8.095
AS - Asia 6.207
SA - Sud America 1.061
AF - Africa 213
OC - Oceania 87
Totale 29.305
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Nazione #
US - Stati Uniti d'America 13.479
RU - Federazione Russa 2.921
SG - Singapore 1.626
CN - Cina 1.555
PL - Polonia 1.264
IT - Italia 1.216
HK - Hong Kong 895
BR - Brasile 832
VN - Vietnam 746
IE - Irlanda 660
SE - Svezia 588
KR - Corea 492
FR - Francia 264
DE - Germania 263
UA - Ucraina 234
IN - India 229
GB - Regno Unito 204
FI - Finlandia 197
BD - Bangladesh 106
CA - Canada 105
JO - Giordania 95
ID - Indonesia 88
AR - Argentina 84
AU - Australia 81
JP - Giappone 72
NL - Olanda 61
PH - Filippine 56
CH - Svizzera 51
TR - Turchia 45
BE - Belgio 44
IQ - Iraq 43
EC - Ecuador 39
CI - Costa d'Avorio 38
ES - Italia 37
EG - Egitto 32
ZA - Sudafrica 32
PK - Pakistan 29
MX - Messico 27
NG - Nigeria 27
CO - Colombia 26
MA - Marocco 24
VE - Venezuela 22
PE - Perù 21
SA - Arabia Saudita 18
UZ - Uzbekistan 17
AE - Emirati Arabi Uniti 16
PY - Paraguay 15
CL - Cile 14
DZ - Algeria 13
TW - Taiwan 13
SC - Seychelles 12
CZ - Repubblica Ceca 11
DK - Danimarca 10
LT - Lituania 10
RO - Romania 10
AZ - Azerbaigian 8
KE - Kenya 8
TN - Tunisia 8
AL - Albania 7
BH - Bahrain 7
IR - Iran 7
CR - Costa Rica 6
GR - Grecia 6
HR - Croazia 6
PT - Portogallo 6
BG - Bulgaria 5
GT - Guatemala 5
HN - Honduras 5
JM - Giamaica 5
MY - Malesia 5
NP - Nepal 5
NZ - Nuova Zelanda 5
TH - Thailandia 5
AT - Austria 4
BJ - Benin 4
BO - Bolivia 4
KG - Kirghizistan 4
MG - Madagascar 4
SN - Senegal 4
HU - Ungheria 3
IL - Israele 3
LB - Libano 3
PS - Palestinian Territory 3
UY - Uruguay 3
BB - Barbados 2
CY - Cipro 2
DO - Repubblica Dominicana 2
ET - Etiopia 2
KZ - Kazakistan 2
LK - Sri Lanka 2
MN - Mongolia 2
PA - Panama 2
RS - Serbia 2
SK - Slovacchia (Repubblica Slovacca) 2
SV - El Salvador 2
SY - Repubblica araba siriana 2
ZM - Zambia 2
BA - Bosnia-Erzegovina 1
BY - Bielorussia 1
CG - Congo 1
Totale 29.286
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Città #
Santa Clara 3.188
Ashburn 1.527
Warsaw 1.255
Singapore 1.170
Fairfield 1.125
Hong Kong 739
Dublin 657
Chandler 582
Woodbridge 537
Seoul 480
Seattle 441
Houston 422
Cambridge 392
Wilmington 377
Jacksonville 348
Beijing 331
San Jose 321
Ann Arbor 320
Hefei 301
Ho Chi Minh City 266
Altamura 243
Florence 239
Los Angeles 219
Lawrence 217
The Dalles 188
Buffalo 180
Princeton 173
Lauterbourg 172
Council Bluffs 154
Hanoi 148
Moscow 142
Boston 140
Mumbai 129
Dallas 117
Boardman 113
New York 89
Milan 88
Melbourne 75
São Paulo 73
Helsinki 68
Kent 65
San Diego 64
Medford 61
Shanghai 60
Tokyo 59
Rome 56
Clifton 50
Jakarta 50
Paris 49
Munich 48
Bern 43
Brussels 41
Abidjan 38
Norwalk 36
Haiphong 35
Toronto 35
London 34
West Jordan 33
Chicago 31
Redondo Beach 30
Dong Ket 27
Hangzhou 27
Abuja 26
Biên Hòa 25
Da Nang 25
Orem 25
Naples 24
Amsterdam 23
Lappeenranta 23
Phoenix 23
Washington 23
Frankfurt am Main 22
Montreal 22
Andover 21
Izmir 21
Tianjin 20
Yubileyny 20
Rio de Janeiro 19
Turku 19
Brasília 18
Denver 18
Guangzhou 18
Bengaluru 17
Hillsboro 17
Belo Horizonte 16
Lima 16
San Francisco 16
Miano 15
Amman 14
Atlanta 14
Falls Church 14
Gavirate 14
Johannesburg 14
Tashkent 14
Baghdad 13
Brooklyn 13
Cairo 13
Cape Town 13
Chennai 13
Porto Alegre 13
Totale 19.412
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Nome #
Computational approaches in drug discovery: strategies to address polypharmacology and the synthesis/optimization of lead compounds 367
Design, synthesis and binding affinity of new nicotinic ligands 350
Insights into docking and scoring neuronal 42 nicotinic receptor agonists using Molecular Dynamics simulations and QM/MM calculations 315
Synthesis, biological evaluation and docking studies of casuarine analogs: effects of structural modifications at ring B on inhibitory activity towards glucoamylase 311
Cation, anion and ion-pair complexes with a G-3 poly(ethylene imine) dendrimer in aqueous solution 296
β3-adrenoreceptor activity limits apigenin efficacy in ewing sarcoma cells: A dual approach to prevent cell survival 275
DNA binding by a new metallointercalator that contains a proflavine group bearing a hanging chelating unit. 274
2-Benzylpiperazine: a new scaffold for potent human Carbonic Anhydrase inhibitors. Synthesis, enzyme inhibition, enantioselectivity, computational and crystallographic studies and in vivo activity for a new class of intraocular pressure lowering agents. 272
Synthesis and biological evaluation of novel 9-heteroaryl substituted 7-chloro-4,5-dihydro-4-oxo-1,2,4-triazolo[1,5-a]quinoxaline-2-carboxylates (TQX) as AMPA receptor antagonists. 251
4-Hydroxy-3-nitro-5-ureido-benzenesulfonamides selectively target the tumor-associated carbonic anhydrase isoforms IX and XII showing hypoxia-enhanced anti-proliferative profiles. 250
Dual-tail arylsulfone-based benzenesulfonamides differently match the hydrophobic and hydrophilic halves of human carbonic anhydrases active sites: Selective inhibitors for the tumor-associated hCA IX isoform 250
Development of a new home-care detergent: experimental design in the optimization of performances and study on the safety of use through physico-chemical and toxicological data 242
Lipoyl-Homotaurine Derivative (ADM_12) Reverts Oxaliplatin-Induced Neuropathy and Reduces Cancer Cells Malignancy by Inhibiting Carbonic Anhydrase IX (CAIX) 233
Solid state and solution study on the formation of inorganic anion complexes with a series of tetrazine-based ligands 225
Determinants for Tight and Selective Binding of a Medicinal Dicarbene Gold(I) Complex to a Telomeric DNA G-Quadruplex: a Joint ESI MS and XRD Investigation 222
Tales of the unexpected: The case of zirconium(IV) complexes with desferrioxamine 220
Enhanced curcumin permeability by SLN formulation: The PAMPA approach 220
Discovery of β-Adrenergic Receptors Blocker-Carbonic Anhydrase Inhibitor Hybrids for Multitargeted Antiglaucoma Therapy 217
The antibiotic furagin and its derivatives are isoform-selective human carbonic anhydrase inhibitors 214
Tuning the Activity of Zn(II) Complexes in DNA Cleavage: Clues for Design of New Efficient Metallo-Hydrolases 212
2-(2-Hydroxyethyl)piperazine derivatives as potent human carbonic anhydrase inhibitors: Synthesis, enzyme inhibition, computational studies and antiglaucoma activity 211
Novel diamide-based benzenesulfonamides as selective carbonic anhydrase ix inhibitors endowed with antitumor activity: Synthesis, biological evaluation and in silico insights 210
Central Nicotinic receptors: structure, function, ligands, and therapeutic potential 207
A highly pH-sensitive Zn(II) chemosensor 207
Role of the Benzodioxole Group in the Interactions between the Natural Alkaloids Chelerythrine and Coptisine and the Human Telomeric G-Quadruplex DNA. A Multiapproach Investigation 205
[Au(9-methylcaffein-8-ylidene)2]+/DNA Tel23 System: Solution, Computational, and Biological Studies 203
Analisi statistica dei dati, convalida dei metodi analitici e introduzione alle carte di controllo 201
From random to rational: A discovery approach to selective subnanomolar inhibitors of human carbonic anhydrase IV based on the Castagnoli-Cushman multicomponent reaction 198
Benzenesulfonamides Incorporating Flexible Triazole Moieties Are Highly Effective Carbonic Anhydrase Inhibitors: Synthesis and Kinetic, Crystallographic, Computational, and Intraocular Pressure Lowering Investigations 197
Deciphering the Mechanism of Human Carbonic Anhydrases Inhibition with Sulfocoumarins: Computational and Experimental Studies 195
ADSORPTIVE STRIPPING VOLTAMMETRY FOR THIOMERSAL ASSAY. 193
Synthesis and Benzodiazepine Receptor Affinity of Pyrazolo [1,5-a]pyrimidine Derivatives.3. New 6-(3-Thienyl) Series as a1 Selective Ligands 192
Searching for a reliable orientation of ligands in their binding site: Glide versus FIGO in the case study of PDE4 inhibitorsJ. Med. Chem., , 48(5), 1657-65 192
Aryl-4,5-dihydro-1H-pyrazole-1-carboxamide derivatives bearing a sulfonamide moiety show single-digit nanomolar-to-subnanomolar inhibition constants against the tumor-associated human carbonic anhydrases IX and XII 190
Dual Inhibitors of Brain Carbonic Anhydrases and Monoamine Oxidase-B Efficiently Protect against Amyloid-β-Induced Neuronal Toxicity, Oxidative Stress, and Mitochondrial Dysfunction 189
Binding of H+ and Zn(II) ions with a new fluorescent macrocyclic phenanthrolinophane. 188
Spectroscopic, molecular modeling and NMR-spectroscopic investigation of the binding mode of the natural alkaloids berberine and sanguinarine to human telomeric G-quadruplex DNA 187
Hypericins and Thioredoxin Reductase: Biochemical and Docking Studies disclose the Molecular Basis for Effective Inhibition by Naphthodianthrones 187
Insights into the Conformational Switching Mechanism of the Human Vascular Endothelial Growth Factor Receptor Type 2 Kinase Domain 185
Structural Investigation of the 7-Chloro-3-hydroxy-1H-quinazoline-2,4-dione Scaffold to Obtain AMPA and Kainate Receptor Selective Antagonists. Synthesis, Pharmacological and Molecular Modeling Studies 184
A novel selective GABA-A alpha1 receptor agonist displaying sedative and anxiolytic-like properties in rodents. 181
GRIND-derived pharmacophore model for a series of α-tropanyl derivative ligands of the sigma-2 receptor 181
Selective binding and fluorescence sensing of diphosphate in H2O via Zn2+-induced allosteric regulation of the receptor structure 180
DNA interaction with Ru(II) and Ru(II)/Cu(II) complexes containing azamacrocycle and dppz residues. A thermodynamic, kinetic and theoretical study. 176
Homology modeling, docking and MM-GBSA rescoring of benzodiazepine receptor ligands: structural features regulating alpha1-versus alpha5- subtype selectivity 175
Anion and ion-pair binding by a G-2 poly(ethylene imine) dendrimer 175
Chpater 19 Carbonic Anhydrases from Pathogens: Fungal Carbonic Anhydrases And Their Inhibitors as Potential Antifungal Agents. 174
Pyrrolyl and Indolyl alpha-gamma-Diketo Acid Derivatives Acting as Selective Inhibitors of Human Carbonic Anhydrases IX and XII 173
Antagonism/agonism modulation to build novel antihypertensives selectively triggering I1-imidazoline receptor activation 173
Discovery of New Sulfonamide Carbonic Anhydrase IX Inhibitors Incorporating Nitrogenous Bases 173
Binding of berberine and sanguinarine with G-quadruplex and duplex DNA revealed by surface-enhanced Raman spectroscopy 173
New docking CFF91 parameters specific for cyclodextrin inclusion complexes 172
Synthesis, SAR and in Vitro Evaluation of New Cyclic Arg-Gly-Asp Pseudopentapeptides Containing a s-cis Peptide Bond as Integrin alpha-v-beta3 and alpha-v-beta5 Ligands. 172
Solution and Solid-State Analysis of Binding of 13-Substituted Berberine Analogues to Human Telomeric G-quadruplexes 171
Bioisosteric Development of Multitarget Nonsteroidal Anti-Inflammatory Drug-Carbonic Anhydrases Inhibitor Hybrids for the Management of Rheumatoid Arthritis 171
Modeling and Biological Investigations of an Unusual Behavior of Novel Synthesized Acridine- Based Polyamine Ligands in the Binding of Double Helix and G-Quadruplex DNA 170
GRID-DOCKING STUDY ON LIGANDS ACTING AS INHIBITORS OF THE HUMAN PHOSPHODIESTERASE 4 169
DEVELOPMENT AND SET-UP OF DRUG ELECTROANALYSIS BY EXPERIMENTAL DESIGN: A SURVEY. 169
GRID INDEPENDENT DESCRIPTORS (GRIND) IN THE STUDY OF THE S-RECEPTOR SUBTYPE SELECTIVITY. 167
Adsorptive stripping voltammetry in pharmaceutical analysis 167
Sensing Zn2+ in aqueous solution with a fluorescent scorpiand macrocyclic ligand decorated with an anthracene bearing tail 167
Sulfonamide Inhibitors of Human Carbonic Anhydrases Designed through a Three-Tails Approach: Improving Ligand/Isoform Matching and Selectivity of Action 167
Design and synthesis of sulfonamides incorporating a biotin moiety: Carbonic anhydrase inhibitory effects, antiproliferative activity and molecular modeling studies 166
N-Nitrosulfonamides as Carbonic Anhydrase Inhibitors: A Promising Chemotype for Targeting Chagas Disease and Leishmaniasis 165
Determination of isosorbide-5-mononitrate in tablets by differential pulse polarography. 164
Simultaneous determination of otilonium bromide and diazepam by high performance liquid chromatography. 164
New Rigid Nicotine Analogues, Carrying a Norbornane Moiety, Are Potent Agonists of α7 and α3∗ Nicotinic Receptors 164
Differential-pulse adsorptive stripping voltammetry of chlorhexidine 163
The crystal structure of human telomeric DNA complexed with berberine: an interesting case of stacked ligand to G-tetrad ratio higher than 1:1 162
A Series of Thiadiazolyl-Benzenesulfonamides Incorporating an Aromatic Tail as Isoform-Selective, Potent Carbonic Anhydrase II/XII Inhibitors 161
Computationally enhanced X-ray diffraction analysis of a gold(III) complex interacting with the human telomeric DNA G-quadruplex. Unravelling non-unique ligand positioning 161
Differential electrolytic potentiometry (DEP) with twin silver-silver sulphide membrane electrodes in micro titration of quaternary ammonium compounds 161
Charactherization of Sanguinaria canadensis extract by positive ion FAB mass spectrometry 161
4-Substituted benzenesulfonamides featuring cyclic imides moieties exhibit potent and isoform-selective carbonic anhydrase II/IX inhibition 161
Solution NMR Structure of a Ligand/Hybrid-2-G-Quadruplex Complex Reveals Rearrangements that Affect Ligand Binding 161
Halogenated isophthalamides and dipicolineamides: The role of the halogen substituents in the anion binding properties 161
Synthesis of new 1,3- dicyclohexyl barbituric acid derivatives with anti-inflammatory potential activity. 159
Inhibition of Malassezia globosa carbonic anhydrase with phenols 158
Novel indolin-2-one-based sulfonamides as carbonic anhydrase inhibitors: Synthesis, in vitro biological evaluation against carbonic anhydrases isoforms I, II, IV and VII and molecular docking studies 158
Enhanced Recognition Memory through Dual Modulation of Brain Carbonic Anhydrases and Cholinesterases 156
Metal ion binding by a G-2 poly(ethylene imine) dendrimer. Ion-directed self-assembling of hierarchical mono- and two-dimensional nanostructured materials 156
Inhibition of the β-carbonic anhydrase from the dandruff-producing fungus Malassezia globosa with monothiocarbamates 156
Discovery of New 1,1′-Biphenyl-4-sulfonamides as Selective Subnanomolar Human Carbonic Anhydrase II Inhibitors 156
La casuarina ed il suo glucoside: sintesi e studio della loro interazione con glucoamilasi 155
3-Hydrazinoisatin-based benzenesulfonamides as novel carbonic anhydrase inhibitors endowed with anticancer activity: Synthesis, in vitro biological evaluation and in silico insights 154
3-Methylthiazolo[3,2-a]benzimidazole-benzenesulfonamide conjugates as novel carbonic anhydrase inhibitors endowed with anticancer activity: Design, synthesis, biological and molecular modeling studies 154
Assessment of human telomeric G-quadruplex structures using surface-enhanced Raman spectroscopy 154
Insight into 2-phenylpyrazolo[1,5-a]pyrimidin-3-yl acetamides as Peripheral Benzodiazepine Receptor Ligands: synthesis, biological evaluation and 3D-QSAR investigation. 153
Appraisal of anti-protozoan activity of nitroaromatic benzenesulfonamides inhibiting carbonic anhydrases from Trypanosoma cruzi and Leishmania donovani 153
6-Substituted Triazolyl Benzoxaboroles as Selective Carbonic Anhydrase Inhibitors: In Silico Design, Synthesis, and X-ray Crystallography 152
HIGH-PERFORMANCE LIQUID CHROMATOGRAPHIC DETERMINATION OF BENZALKONIUM AND NAPHAZOLINE OR TETRAHYDROZOLINE IN NASAL AND OPHTHALMIC SOLUTIONS. 152
Polypharmacology of epacadostat: A potent and selective inhibitor of the tumor associated carbonic anhydrases IX and XII 152
Effect of structure levels on surface-enhanced Raman scattering of human telomeric G-quadruplexes in diluted and crowded media 152
Selenols: a new class of carbonic anhydrase inhibitors 151
Interaction of a gold(i) dicarbene anticancer drug with human telomeric DNA G-quadruplex: solution and computationally aided X-ray diffraction analysis 151
Continued exploration and tail approach synthesis of benzenesulfonamides containing triazole and dual triazole moieties as carbonic anhydrase I, II, IV and IX inhibitors 151
Chromatographic analysis of picotamide and its impurities 150
Determination of benzalkonium chloride in contact lens solutions by positive ion FAB mass spectrometry. 149
3D-QSAR, GRID DESCRIPTORS AND CHEMOMETRIC TOOLS IN THE DEVELOPMENT OF SELECTIVE ANTAGONIST OF MUSCARINIC RECEPTOR. 149
Discovery of first-in-class multi-target adenosine A2A receptor antagonists-carbonic anhydrase IX and XII inhibitors. 8-Amino-6-aryl-2-phenyl-1,2,4-triazolo [4,3-a]pyrazin-3-one derivatives as new potential antitumor agents 149
Totale 18.888
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Categoria #
all - tutte 84.393
article - articoli 0
book - libri 0
conference - conferenze 0
curatela - curatele 0
other - altro 0
patent - brevetti 0
selected - selezionate 0
volume - volumi 0
Totale 84.393
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Totale Lug Ago Sett Ott Nov Dic Gen Feb Mar Apr Mag Giu
2020/2021132 0 0 0 0 0 0 0 0 0 0 0 132
2021/20221.238 35 81 114 60 34 56 60 109 104 65 222 298
2022/20233.018 299 658 167 176 213 492 394 129 296 49 70 75
2023/20241.191 35 126 193 82 85 124 52 250 28 108 78 30
2024/20258.618 309 846 569 1.197 2.532 1.312 184 401 402 234 316 316
2025/20269.043 926 1.299 979 953 995 345 1.064 564 612 626 453 227
Totale 29.652