GRATTERI, PAOLA
 Distribuzione geografica
Continente #
NA - Nord America 12.014
EU - Europa 7.567
AS - Asia 4.739
SA - Sud America 997
AF - Africa 166
OC - Oceania 83
Totale 25.566
Nazione #
US - Stati Uniti d'America 11.914
RU - Federazione Russa 2.919
PL - Polonia 1.257
SG - Singapore 1.222
CN - Cina 1.181
IT - Italia 1.029
HK - Hong Kong 860
BR - Brasile 801
IE - Irlanda 658
SE - Svezia 577
KR - Corea 483
VN - Vietnam 348
DE - Germania 246
UA - Ucraina 230
IN - India 195
GB - Regno Unito 183
FI - Finlandia 141
JO - Giordania 88
ID - Indonesia 86
AU - Australia 80
FR - Francia 80
AR - Argentina 76
CA - Canada 64
CH - Svizzera 50
PH - Filippine 50
NL - Olanda 49
BE - Belgio 44
TR - Turchia 39
CI - Costa d'Avorio 36
ES - Italia 33
EC - Ecuador 31
JP - Giappone 31
EG - Egitto 27
ZA - Sudafrica 27
IQ - Iraq 26
BD - Bangladesh 24
CO - Colombia 21
PE - Perù 20
MA - Marocco 19
VE - Venezuela 17
MX - Messico 16
PK - Pakistan 16
PY - Paraguay 15
DZ - Algeria 13
UZ - Uzbekistan 13
SA - Arabia Saudita 12
SC - Seychelles 12
CL - Cile 11
TW - Taiwan 11
DK - Danimarca 10
CZ - Repubblica Ceca 9
RO - Romania 9
AE - Emirati Arabi Uniti 8
KE - Kenya 8
AL - Albania 7
IR - Iran 7
LT - Lituania 7
TN - Tunisia 7
AZ - Azerbaigian 5
BH - Bahrain 5
BG - Bulgaria 4
BJ - Benin 4
HN - Honduras 4
HR - Croazia 4
JM - Giamaica 4
KG - Kirghizistan 4
MG - Madagascar 4
TH - Thailandia 4
AT - Austria 3
CR - Costa Rica 3
LB - Libano 3
MY - Malesia 3
PS - Palestinian Territory 3
PT - Portogallo 3
SN - Senegal 3
BO - Bolivia 2
DO - Repubblica Dominicana 2
HU - Ungheria 2
LK - Sri Lanka 2
NZ - Nuova Zelanda 2
PA - Panama 2
RS - Serbia 2
SK - Slovacchia (Repubblica Slovacca) 2
SV - El Salvador 2
UY - Uruguay 2
ZM - Zambia 2
BA - Bosnia-Erzegovina 1
BY - Bielorussia 1
CY - Cipro 1
ET - Etiopia 1
GF - Guiana Francese 1
GH - Ghana 1
GR - Grecia 1
GT - Guatemala 1
IL - Israele 1
KH - Cambogia 1
KI - Kiribati 1
KW - Kuwait 1
KZ - Kazakistan 1
LU - Lussemburgo 1
Totale 25.552
Città #
Santa Clara 3.166
Warsaw 1.250
Fairfield 1.124
Ashburn 971
Singapore 809
Hong Kong 714
Dublin 655
Chandler 582
Woodbridge 537
Seoul 480
Seattle 440
Houston 420
Cambridge 390
Wilmington 376
Jacksonville 343
Ann Arbor 320
Beijing 304
Hefei 299
Altamura 243
Florence 228
Lawrence 217
Los Angeles 176
Princeton 172
Buffalo 168
Moscow 142
Ho Chi Minh City 141
Boston 139
Mumbai 123
Dallas 108
Boardman 104
Melbourne 73
São Paulo 71
The Dalles 66
Kent 65
San Diego 63
Medford 59
Shanghai 58
Hanoi 56
Milan 56
New York 52
Clifton 50
Jakarta 50
Munich 48
Paris 44
Rome 44
Bern 43
Brussels 41
Abidjan 36
Norwalk 36
West Jordan 33
Council Bluffs 32
London 31
Redondo Beach 30
Dong Ket 27
Toronto 27
Hangzhou 26
Chicago 25
Andover 21
Izmir 21
Tokyo 21
Yubileyny 20
Naples 19
Rio de Janeiro 19
Turku 19
Haiphong 18
Lappeenranta 18
Tianjin 18
Helsinki 17
Hillsboro 17
Phoenix 17
Belo Horizonte 16
Bengaluru 16
Brasília 16
Lima 16
Montreal 15
Biên Hòa 14
Falls Church 14
Gavirate 14
Redwood City 13
Amsterdam 12
Auburn Hills 12
Cape Town 12
Cebu City 12
Denver 12
Fortaleza 12
Frankfurt Am Main 12
Frankfurt am Main 12
Porto Alegre 12
Washington 12
Barcelona 11
Brooklyn 11
Cairo 11
Johannesburg 11
Livorno 11
Philadelphia 11
San Francisco 11
Tashkent 11
Atlanta 10
Baghdad 10
Dearborn 10
Totale 17.000
Nome #
Design, synthesis and binding affinity of new nicotinic ligands 325
Insights into docking and scoring neuronal 42 nicotinic receptor agonists using Molecular Dynamics simulations and QM/MM calculations 280
Synthesis, biological evaluation and docking studies of casuarine analogs: effects of structural modifications at ring B on inhibitory activity towards glucoamylase 280
Cation, anion and ion-pair complexes with a G-3 poly(ethylene imine) dendrimer in aqueous solution 272
Computational approaches in drug discovery: strategies to address polypharmacology and the synthesis/optimization of lead compounds 265
DNA binding by a new metallointercalator that contains a proflavine group bearing a hanging chelating unit. 263
β3-adrenoreceptor activity limits apigenin efficacy in ewing sarcoma cells: A dual approach to prevent cell survival 246
Dual-tail arylsulfone-based benzenesulfonamides differently match the hydrophobic and hydrophilic halves of human carbonic anhydrases active sites: Selective inhibitors for the tumor-associated hCA IX isoform 238
Synthesis and biological evaluation of novel 9-heteroaryl substituted 7-chloro-4,5-dihydro-4-oxo-1,2,4-triazolo[1,5-a]quinoxaline-2-carboxylates (TQX) as AMPA receptor antagonists. 234
2-Benzylpiperazine: a new scaffold for potent human Carbonic Anhydrase inhibitors. Synthesis, enzyme inhibition, enantioselectivity, computational and crystallographic studies and in vivo activity for a new class of intraocular pressure lowering agents. 224
4-Hydroxy-3-nitro-5-ureido-benzenesulfonamides selectively target the tumor-associated carbonic anhydrase isoforms IX and XII showing hypoxia-enhanced anti-proliferative profiles. 218
Lipoyl-Homotaurine Derivative (ADM_12) Reverts Oxaliplatin-Induced Neuropathy and Reduces Cancer Cells Malignancy by Inhibiting Carbonic Anhydrase IX (CAIX) 216
Development of a new home-care detergent: experimental design in the optimization of performances and study on the safety of use through physico-chemical and toxicological data 207
Tales of the unexpected: The case of zirconium(IV) complexes with desferrioxamine 203
Solid state and solution study on the formation of inorganic anion complexes with a series of tetrazine-based ligands 198
Enhanced curcumin permeability by SLN formulation: The PAMPA approach 198
Tuning the Activity of Zn(II) Complexes in DNA Cleavage: Clues for Design of New Efficient Metallo-Hydrolases 197
Novel diamide-based benzenesulfonamides as selective carbonic anhydrase ix inhibitors endowed with antitumor activity: Synthesis, biological evaluation and in silico insights 189
Determinants for Tight and Selective Binding of a Medicinal Dicarbene Gold(I) Complex to a Telomeric DNA G-Quadruplex: a Joint ESI MS and XRD Investigation 186
A highly pH-sensitive Zn(II) chemosensor 185
Discovery of β-Adrenergic Receptors Blocker-Carbonic Anhydrase Inhibitor Hybrids for Multitargeted Antiglaucoma Therapy 185
The antibiotic furagin and its derivatives are isoform-selective human carbonic anhydrase inhibitors 184
Central Nicotinic receptors: structure, function, ligands, and therapeutic potential 183
Deciphering the Mechanism of Human Carbonic Anhydrases Inhibition with Sulfocoumarins: Computational and Experimental Studies 182
[Au(9-methylcaffein-8-ylidene)2]+/DNA Tel23 System: Solution, Computational, and Biological Studies 182
Analisi statistica dei dati, convalida dei metodi analitici e introduzione alle carte di controllo 179
Role of the Benzodioxole Group in the Interactions between the Natural Alkaloids Chelerythrine and Coptisine and the Human Telomeric G-Quadruplex DNA. A Multiapproach Investigation 179
ADSORPTIVE STRIPPING VOLTAMMETRY FOR THIOMERSAL ASSAY. 178
Synthesis and Benzodiazepine Receptor Affinity of Pyrazolo [1,5-a]pyrimidine Derivatives.3. New 6-(3-Thienyl) Series as a1 Selective Ligands 178
Searching for a reliable orientation of ligands in their binding site: Glide versus FIGO in the case study of PDE4 inhibitorsJ. Med. Chem., , 48(5), 1657-65 174
Hypericins and Thioredoxin Reductase: Biochemical and Docking Studies disclose the Molecular Basis for Effective Inhibition by Naphthodianthrones 174
Selective binding and fluorescence sensing of diphosphate in H2O via Zn2+-induced allosteric regulation of the receptor structure 173
Insights into the Conformational Switching Mechanism of the Human Vascular Endothelial Growth Factor Receptor Type 2 Kinase Domain 172
From random to rational: A discovery approach to selective subnanomolar inhibitors of human carbonic anhydrase IV based on the Castagnoli-Cushman multicomponent reaction 171
2-(2-Hydroxyethyl)piperazine derivatives as potent human carbonic anhydrase inhibitors: Synthesis, enzyme inhibition, computational studies and antiglaucoma activity 171
Spectroscopic, molecular modeling and NMR-spectroscopic investigation of the binding mode of the natural alkaloids berberine and sanguinarine to human telomeric G-quadruplex DNA 170
Aryl-4,5-dihydro-1H-pyrazole-1-carboxamide derivatives bearing a sulfonamide moiety show single-digit nanomolar-to-subnanomolar inhibition constants against the tumor-associated human carbonic anhydrases IX and XII 168
GRIND-derived pharmacophore model for a series of α-tropanyl derivative ligands of the sigma-2 receptor 165
Benzenesulfonamides Incorporating Flexible Triazole Moieties Are Highly Effective Carbonic Anhydrase Inhibitors: Synthesis and Kinetic, Crystallographic, Computational, and Intraocular Pressure Lowering Investigations 165
Binding of H+ and Zn(II) ions with a new fluorescent macrocyclic phenanthrolinophane. 163
Structural Investigation of the 7-Chloro-3-hydroxy-1H-quinazoline-2,4-dione Scaffold to Obtain AMPA and Kainate Receptor Selective Antagonists. Synthesis, Pharmacological and Molecular Modeling Studies 162
Homology modeling, docking and MM-GBSA rescoring of benzodiazepine receptor ligands: structural features regulating alpha1-versus alpha5- subtype selectivity 162
A novel selective GABA-A alpha1 receptor agonist displaying sedative and anxiolytic-like properties in rodents. 161
Chpater 19 Carbonic Anhydrases from Pathogens: Fungal Carbonic Anhydrases And Their Inhibitors as Potential Antifungal Agents. 160
DEVELOPMENT AND SET-UP OF DRUG ELECTROANALYSIS BY EXPERIMENTAL DESIGN: A SURVEY. 158
Solution and Solid-State Analysis of Binding of 13-Substituted Berberine Analogues to Human Telomeric G-quadruplexes 158
Sensing Zn2+ in aqueous solution with a fluorescent scorpiand macrocyclic ligand decorated with an anthracene bearing tail 157
Antagonism/agonism modulation to build novel antihypertensives selectively triggering I1-imidazoline receptor activation 155
Discovery of New Sulfonamide Carbonic Anhydrase IX Inhibitors Incorporating Nitrogenous Bases 155
Pyrrolyl and Indolyl alpha-gamma-Diketo Acid Derivatives Acting as Selective Inhibitors of Human Carbonic Anhydrases IX and XII 154
Differential electrolytic potentiometry (DEP) with twin silver-silver sulphide membrane electrodes in micro titration of quaternary ammonium compounds 154
Determination of isosorbide-5-mononitrate in tablets by differential pulse polarography. 154
DNA interaction with Ru(II) and Ru(II)/Cu(II) complexes containing azamacrocycle and dppz residues. A thermodynamic, kinetic and theoretical study. 153
Differential-pulse adsorptive stripping voltammetry of chlorhexidine 153
Anion and ion-pair binding by a G-2 poly(ethylene imine) dendrimer 153
Binding of berberine and sanguinarine with G-quadruplex and duplex DNA revealed by surface-enhanced Raman spectroscopy 152
Simultaneous determination of otilonium bromide and diazepam by high performance liquid chromatography. 151
Synthesis of new 1,3- dicyclohexyl barbituric acid derivatives with anti-inflammatory potential activity. 151
Solution NMR Structure of a Ligand/Hybrid-2-G-Quadruplex Complex Reveals Rearrangements that Affect Ligand Binding 150
GRID-DOCKING STUDY ON LIGANDS ACTING AS INHIBITORS OF THE HUMAN PHOSPHODIESTERASE 4 149
Inhibition of Malassezia globosa carbonic anhydrase with phenols 149
Synthesis, SAR and in Vitro Evaluation of New Cyclic Arg-Gly-Asp Pseudopentapeptides Containing a s-cis Peptide Bond as Integrin alpha-v-beta3 and alpha-v-beta5 Ligands. 149
New docking CFF91 parameters specific for cyclodextrin inclusion complexes 148
N-Nitrosulfonamides as Carbonic Anhydrase Inhibitors: A Promising Chemotype for Targeting Chagas Disease and Leishmaniasis 148
Charactherization of Sanguinaria canadensis extract by positive ion FAB mass spectrometry 147
Bioisosteric Development of Multitarget Nonsteroidal Anti-Inflammatory Drug-Carbonic Anhydrases Inhibitor Hybrids for the Management of Rheumatoid Arthritis 146
Modeling and Biological Investigations of an Unusual Behavior of Novel Synthesized Acridine- Based Polyamine Ligands in the Binding of Double Helix and G-Quadruplex DNA 146
Design and synthesis of sulfonamides incorporating a biotin moiety: Carbonic anhydrase inhibitory effects, antiproliferative activity and molecular modeling studies 145
Sulfonamide Inhibitors of Human Carbonic Anhydrases Designed through a Three-Tails Approach: Improving Ligand/Isoform Matching and Selectivity of Action 144
HIGH-PERFORMANCE LIQUID CHROMATOGRAPHIC DETERMINATION OF BENZALKONIUM AND NAPHAZOLINE OR TETRAHYDROZOLINE IN NASAL AND OPHTHALMIC SOLUTIONS. 143
Halogenated isophthalamides and dipicolineamides: The role of the halogen substituents in the anion binding properties 143
Dual Inhibitors of Brain Carbonic Anhydrases and Monoamine Oxidase-B Efficiently Protect against Amyloid-β-Induced Neuronal Toxicity, Oxidative Stress, and Mitochondrial Dysfunction 142
GRID INDEPENDENT DESCRIPTORS (GRIND) IN THE STUDY OF THE S-RECEPTOR SUBTYPE SELECTIVITY. 142
Inhibition of the β-carbonic anhydrase from the dandruff-producing fungus Malassezia globosa with monothiocarbamates 142
Adsorptive stripping voltammetry in pharmaceutical analysis 141
New Rigid Nicotine Analogues, Carrying a Norbornane Moiety, Are Potent Agonists of α7 and α3∗ Nicotinic Receptors 141
4-Substituted benzenesulfonamides featuring cyclic imides moieties exhibit potent and isoform-selective carbonic anhydrase II/IX inhibition 141
Polypharmacology of epacadostat: A potent and selective inhibitor of the tumor associated carbonic anhydrases IX and XII 141
Continued exploration and tail approach synthesis of benzenesulfonamides containing triazole and dual triazole moieties as carbonic anhydrase I, II, IV and IX inhibitors 141
Assessment of human telomeric G-quadruplex structures using surface-enhanced Raman spectroscopy 140
Insight into 2-phenylpyrazolo[1,5-a]pyrimidin-3-yl acetamides as Peripheral Benzodiazepine Receptor Ligands: synthesis, biological evaluation and 3D-QSAR investigation. 139
Selenols: a new class of carbonic anhydrase inhibitors 139
3-Hydrazinoisatin-based benzenesulfonamides as novel carbonic anhydrase inhibitors endowed with anticancer activity: Synthesis, in vitro biological evaluation and in silico insights 139
A Series of Thiadiazolyl-Benzenesulfonamides Incorporating an Aromatic Tail as Isoform-Selective, Potent Carbonic Anhydrase II/XII Inhibitors 138
EXPERIMENTAL DESIGN STRATEGIES IN THE OPTIMIZATION AND ROBUSTNESS TESTING OF ADSORPTIVE STRIPPING VOLTAMMETRIC CONDITIONS FOR KYNURENIC ACID DETERMINATION. 138
Metal ion binding by a G-2 poly(ethylene imine) dendrimer. Ion-directed self-assembling of hierarchical mono- and two-dimensional nanostructured materials 137
La casuarina ed il suo glucoside: sintesi e studio della loro interazione con glucoamilasi 137
3-Methylthiazolo[3,2-a]benzimidazole-benzenesulfonamide conjugates as novel carbonic anhydrase inhibitors endowed with anticancer activity: Design, synthesis, biological and molecular modeling studies 136
Novel indolin-2-one-based sulfonamides as carbonic anhydrase inhibitors: Synthesis, in vitro biological evaluation against carbonic anhydrases isoforms I, II, IV and VII and molecular docking studies 136
Determination of flubendazole and its dosage forms by differential pulse polarography and UV spectroscopy. 136
Appraisal of anti-protozoan activity of nitroaromatic benzenesulfonamides inhibiting carbonic anhydrases from Trypanosoma cruzi and Leishmania donovani 136
Synthesis, Computational Studies and Assessment of in Vitro Activity of Squalene Derivatives as Carbonic Anhydrase Inhibitors 136
Computationally enhanced X-ray diffraction analysis of a gold(III) complex interacting with the human telomeric DNA G-quadruplex. Unravelling non-unique ligand positioning 135
X-ray diffraction analyses of the natural isoquinoline alkaloids Berberine and Sanguinarine in complex with double helix DNA d(CGTACG) 135
The crystal structure of human telomeric DNA complexed with berberine: an interesting case of stacked ligand to G-tetrad ratio higher than 1:1 135
6-Substituted Triazolyl Benzoxaboroles as Selective Carbonic Anhydrase Inhibitors: In Silico Design, Synthesis, and X-ray Crystallography 134
Simultaneous UV spectrophotometric determination of procaine hydrochloride and phenazone in an otic formulation. 134
Determination of benzalkonium chloride in contact lens solutions by positive ion FAB mass spectrometry. 134
Diversity Oriented Syntheses of 7-Substituted Lentiginosines 134
3D-QSAR, GRID DESCRIPTORS AND CHEMOMETRIC TOOLS IN THE DEVELOPMENT OF SELECTIVE ANTAGONIST OF MUSCARINIC RECEPTOR. 134
Totale 16.823
Categoria #
all - tutte 74.141
article - articoli 0
book - libri 0
conference - conferenze 0
curatela - curatele 0
other - altro 0
patent - brevetti 0
selected - selezionate 0
volume - volumi 0
Totale 74.141


Totale Lug Ago Sett Ott Nov Dic Gen Feb Mar Apr Mag Giu
2020/20211.317 0 0 0 0 0 300 81 130 194 355 125 132
2021/20221.238 35 81 114 60 34 56 60 109 104 65 222 298
2022/20233.018 299 658 167 176 213 492 394 129 296 49 70 75
2023/20241.191 35 126 193 82 85 124 52 250 28 108 78 30
2024/20258.618 309 846 569 1.197 2.532 1.312 184 401 402 234 316 316
2025/20265.274 926 1.299 979 953 995 122 0 0 0 0 0 0
Totale 25.883