CHIARUGI, ALBERTO
 Distribuzione geografica
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Continente #
NA - Nord America 12.669
EU - Europa 7.421
AS - Asia 5.311
SA - Sud America 643
AF - Africa 125
OC - Oceania 95
Continente sconosciuto - Info sul continente non disponibili 2
Totale 26.266
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Nazione #
US - Stati Uniti d'America 12.494
RU - Federazione Russa 2.484
IT - Italia 1.726
SG - Singapore 1.436
CN - Cina 1.338
PL - Polonia 927
HK - Hong Kong 840
IE - Irlanda 589
VN - Vietnam 521
BR - Brasile 504
SE - Svezia 462
KR - Corea 446
FR - Francia 247
DE - Germania 213
CH - Svizzera 206
BD - Bangladesh 180
FI - Finlandia 172
GB - Regno Unito 158
IN - India 147
CA - Canada 115
AU - Australia 95
UA - Ucraina 89
TR - Turchia 83
JP - Giappone 66
NL - Olanda 57
JO - Giordania 56
AR - Argentina 46
ID - Indonesia 41
CI - Costa d'Avorio 34
MX - Messico 32
EC - Ecuador 28
PK - Pakistan 27
IQ - Iraq 24
ES - Italia 19
ZA - Sudafrica 19
BE - Belgio 16
NG - Nigeria 15
CL - Cile 14
UZ - Uzbekistan 12
VE - Venezuela 12
CO - Colombia 11
PY - Paraguay 11
AE - Emirati Arabi Uniti 10
MA - Marocco 10
PE - Perù 10
EG - Egitto 9
LT - Lituania 9
PH - Filippine 9
RO - Romania 9
SA - Arabia Saudita 9
TN - Tunisia 9
BJ - Benin 8
NP - Nepal 8
CR - Costa Rica 7
IL - Israele 7
MY - Malesia 6
TW - Taiwan 6
UY - Uruguay 6
AT - Austria 5
KE - Kenya 5
AM - Armenia 4
DK - Danimarca 4
DZ - Algeria 4
HN - Honduras 4
HU - Ungheria 4
OM - Oman 4
PT - Portogallo 4
AZ - Azerbaigian 3
BY - Bielorussia 3
IR - Iran 3
JM - Giamaica 3
KG - Kirghizistan 3
KW - Kuwait 3
KZ - Kazakistan 3
LU - Lussemburgo 3
MU - Mauritius 3
TH - Thailandia 3
BG - Bulgaria 2
ET - Etiopia 2
GD - Grenada 2
GT - Guatemala 2
HR - Croazia 2
LB - Libano 2
LV - Lettonia 2
MM - Myanmar 2
MT - Malta 2
PR - Porto Rico 2
PS - Palestinian Territory 2
RS - Serbia 2
SC - Seychelles 2
AL - Albania 1
BB - Barbados 1
BH - Bahrain 1
BN - Brunei Darussalam 1
BZ - Belize 1
DO - Repubblica Dominicana 1
EE - Estonia 1
EU - Europa 1
GE - Georgia 1
GF - Guiana Francese 1
Totale 26.248
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Città #
Santa Clara 2.123
Ashburn 1.573
Fairfield 1.244
Singapore 1.043
Warsaw 916
Hong Kong 707
Chandler 621
Dublin 587
Woodbridge 586
Seattle 548
Cambridge 518
Seoul 442
Houston 430
San Jose 397
Wilmington 393
Beijing 301
Milan 283
Hefei 265
Bern 205
Buffalo 202
Ann Arbor 193
Los Angeles 175
Altamura 163
Lauterbourg 162
Lawrence 162
Rome 157
Princeton 149
Ho Chi Minh City 148
Jacksonville 138
The Dalles 138
Florence 126
Hanoi 120
Council Bluffs 111
Medford 110
Mumbai 96
Boardman 95
New York 93
Melbourne 91
Moscow 91
Dearborn 87
Boston 84
Shanghai 75
San Diego 74
Dallas 71
Munich 67
Izmir 64
Tokyo 59
Chicago 57
Kent 53
Naples 51
São Paulo 48
Bologna 42
Paris 42
London 38
Turin 35
Abidjan 34
Jakarta 34
Toronto 34
Norwalk 33
Helsinki 31
Orem 29
Clifton 28
Da Nang 25
Falls Church 25
Figino 25
Dong Ket 24
Redondo Beach 24
Haiphong 23
Turku 22
Frankfurt am Main 21
Hillsboro 20
Miano 19
Brescia 18
Guangzhou 18
Montreal 18
Palermo 18
Rio de Janeiro 18
Venice 18
Phoenix 17
Brussels 16
Verona 16
Abuja 15
Belo Horizonte 15
Brooklyn 15
Denver 15
Bari 14
Genoa 14
Johannesburg 14
Yubileyny 14
Andover 13
Portsmouth 13
Salt Lake City 13
Tianjin 13
Amsterdam 12
Bengaluru 12
Lahore 12
Lappeenranta 12
Quito 12
Cagliari 11
Modena 11
Totale 17.707
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Nome #
Activation of the histaminergic H3 receptor induces phosphorylation of the Akt/GSK-3 beta pathway in cultured cortical neurons and protects against neurotoxic insults. 331
Insight into molecular and functional properties of NMNAT3 reveals new hints of NAD homeostasis within human mitochondria 306
Interplay between histone acetylation/deacetylation and poly(ADPribosyl)ation in the development of ischemic tolerance in vitro 292
1B-DMT1(-)IRE Expression During Brain Ischemia Contributes to Cell Death Mediated by NF-kB/RelA Acetylation at Lys310 272
Long-Term Effectiveness of Three Anti-CGRP Monoclonal Antibodies in Resistant Chronic Migraine Patients Based on the MIDAS score 267
Dexpramipexole improves bioenergetics and outcome in experimental stroke 258
Comparison of the Anti-Inflammatory and Cytotoxic Potential of Different Corticosteroid Eye Drop Preparations 252
Dexpramipexole Enhances K+ Currents and Inhibits Cell Excitability in the Rat Hippocampus In Vitro 243
Trigeminal ganglion transcriptome analysis in 2 rat models of medication-overuse headache reveals coherent and widespread induction of pronociceptive gene expression patterns 240
A key role for poly(ADP-ribose) polymerase-1 activity during human dendritic cell maturation. 232
Neuroimmunological characterization of a mouse model of primary progressive experimental autoimmune encephalomyelitis and effects of immunosuppressive or neuroprotective strategies on disease evolution 232
Repurposing of dexpramipexole to treatment of neonatal hypoxic/ischemic encephalopathy 225
Enhanced dissolution, permeation and oral bioavailability of aripiprazole mixed micelles: In vitro and in vivo evaluation 218
Early derangement of axonal mitochondria occurs in a mouse model of progressive but not relapsing-remitting multiple sclerosis 217
The NAD metabolome - a key determinant of cancer cell biology. 213
Indoleamine 2,3-dioxygenase+ cells correspond to the BDCA2+ plasmacytoid dendritic cells in human melanoma sentinel nodes 211
Identification of the Nicotinamide Salvage Pathway as a New Toxification Route for Antimetabolites 211
CoQ10-containing eye drops prevent UVB-induced cornea cell damage and increase cornea wound healing by preserving mitochondrial function 210
Dexpramipexole enhances hippocampal synaptic plasticity and memory in the rat 210
The TRPA1 channel mediates the analgesic action of dipyrone and pyrazolone derivatives 207
Increase in the level of proinflammatory cytokine hmgb1 in nasal fluids of patients with rhinitis and its sequestration by glycyrrhizin induces eosinophil cell death 207
Mono-galloyl glucose derivatives are potent poly(ADP-ribose) glycohydrolase (PARG) inhibitors and partially reduce PARP-1-dependent cell death 206
Aspetti clinico - terapeutici delle patologie vitreoretiniche. 204
Low-dose methadone for refractory chronic migraine accompanied by medication-overuse headache: a prospective cohort study 203
"Simple but not simpler": toward a unified picture of energy requirements in cell death. 202
Recent Advances in Pediatric Use of Oral Paracetamol in Fever and Pain Management 199
Neurological basis of AMP-dependent thermoregulation and its relevance to central and peripheral hyperthermia. 199
Poly(ADP-ribose) polymerase-1 is a nuclear epigenetic regulator of mitochondrial DNA repair and transcription 197
Anticonvulsant effect of AMP by direct activation of adenosine A1 receptor. 195
Increased Lacrimal Fluid Level of HMGB1 in Vernal Keratoconjunctivitis 195
Mental Pain Questionnaire: Clinimetric Properties of a Potential Global Person‐Centred Outcome Measure 194
Pharmacological effects of exogenous NAD on mitochondrial bioenergetics, DNA repair, and apoptosis 194
Practical and clinical utility of non-invasive vagus nerve stimulation (nVNS) for the acute treatment of migraine: A post hoc analysis of the randomized, sham-controlled, double-blind PRESTO trial 191
Long-lasting neuroprotection and neurological improvement in stroke models with new, potent and brain permeable inhibitors of poly(ADP-ribose) polymerase. 190
Glucose deprivation converts poly(ADP-ribose) polymerase-1 hyperactivation into a transient energy-producing process. 190
PARP inhibition delays progression of mitochondrial encephalopathy in mice 189
Switching anti-CGRP(R) monoclonal antibodies in multi-assessed non-responder patients and implications for ineffectiveness criteria: A retrospective cohort study 187
Selective PARP-2 inhibitors increase apoptosis in hippocampal slices but protect cortical cells in models of post-ischaemic brain damage. 187
Neurological basis of AMP-dependent thermoregulation and its relevance to central and peripheral hyperthermia 187
Effects of Class II-Selective Histone Deacetylase Inhibitor on Neuromuscular Function and Disease Progression in SOD1-ALS Mice 184
Nicotinamide phosphoribosyltransferase (NAMPT) activity is essential for survival of resting lymphocytes 183
BID mediates neuronal cell death after oxygen/ glucose deprivation and focal cerebral ischemia. 182
Ischemic Neuroprotection by TRPV1 Receptor-Induced Hypothermia 182
Aspetti clinico-terapeutici delle patologie vitreoretiniche. Ediz. illustrata 181
Post onset, oral rapamycin treatment delays development of mitochondrial encephalopathy only at supramaximal doses 181
Effect of Class II HDAC inhibition on glutamate transporter expression and survival in SOD1-ALS mice 180
Dexamethasone promotes a stem-like phenotype in human melanoma cells via tryptophan 2,3 dioxygenase 179
Histone Deacetylase (HDAC) Inhibitors Reduce the Glial Inflammatory Response In Vitro and In Vivo 178
Acute and chronic triptan exposure neither alters rodent cerebral blood flow nor worsens ischemic brain injury 178
Effects of cluster headache preventatives on mouse hypothalamic transcriptional homeostasis 177
Antidromic vasodilatation and the migraine mechanism 175
Validation of the Italian version of the Cluster Headache Impact Questionnaire (CHIQ) 174
Caspase inhibition augments Dichlorvos-induced dopaminergic neuronal cell death by increasing ROS production and PARP1 activation. 173
Kynurenine 3-mono-oxygenase activity and neurotoxic kynurenine metabolites increase in the spinal cord of rats with experimental allergic encephalomyelitis. 172
Mild activation of poly(ADP-ribose) polymerase (PARP) is neuroprotective in rat hippocampal slice models of ischemic tolerance 172
Novel isoquinolinone-derived inhibitors of poly(ADP-ribose) polymerase-1: pharmacological characterization and neuroprotective effects in an in vitro model of cerebral ischemia. 171
Long-term suppression of EAE relapses by pharmacological impairment of epitope spreading 170
Inhibitors of kynurenine hydroxylase and kynureninase increase cerebral formation of kynurenate and have sedative and anticonvulsant activities. 169
Carboxymethyl beta-glucan binds to corneal epithelial cells and increases cell adhesion to laminin and resistance to oxidative stress. 169
Poly(ADP-ribose) polymerase is not involved in the neuroprotection exerted by azithromycin against ischemic stroke in mice 169
Differential effects of the tryptophan metabolite 3-hydroxyanthranilic acid on the proliferation of human CD8+ T cells induced by TCR triggering or homeostatic cytokines. 167
IDENTIFICATION AND MEASUREMENT OF OXINDOLE (2-INDOLINONE) IN THE MAMMALIAN BRAIN AND OTHER RAT ORGANS 165
Synthesis and release of neurotoxic kynurenine metabolites by human monocyte-derived macrophages. 164
18β-glycyrrhetic acid inhibits immune activation triggered by HMGB1, a pro-inflammatory protein found in the tear fluid during conjunctivitis and blepharitis 163
Studies on the pharmacological properties of oxindole (2-hydroxyindole) and 5-hydroxyindole: are they involved in hepatic encephalopathy? 163
The emerging therapeutic potential of sirtuin-interacting drugs: from cell death to lifespan extension. 163
Poly(ADP-ribosyl)ation and stroke. 163
Effectiveness of anti-CGRP monoclonal antibodies on central symptoms of migraine 162
Dysregulation of sphingosine 1 phosphate receptor-1 (S1P1) signaling and regulatory lymphocyte-dependent immunosuppression in a model of post-fingolimod MS rebound. 162
Succinate dehydrogenase subunit B mutations modify human neuroblastoma cell metabolism and proliferation 162
Ultra-rapid brain uptake of subcutaneous sumatriptan in the rat: Implication for cluster headache treatment 161
Dexpramipexole blocks Nav1.8 sodium channels and provides analgesia in multiple nociceptive and neuropathic pain models 161
Histone Deacetylase Inhibitors Counteract CGRP Signaling and Pronociceptive Sensitization in a Rat Model of Medication Overuse Headache 160
Poly (ADP-ribose) polymerase inhibitors attenuate necrotic but not apoptotic neuronal death in experimental models of cerebral ischemia 159
Functional study in a yeast model of a novel succinate-dehydrogenase subunit B gene germline missense mutation (C191Y) diagnosed in a patient affected by a glomus tumor. 159
AMP-dependent hypothermia affords protection from ischemic brain injury. 159
Update on the pathophysiology and treatment of rhinogenic headache: Focus on the ibuprofen/pseudoephedrine combination 157
Predictors of sustained response and effects of the discontinuation of anti-calcitonin gene related peptide antibodies and reinitiation in resistant chronic migraine 157
Poly(ADP-ribose) catabolism triggers AMP-dependent mitochondrial energy failure 156
Therapeutic hypothermia: Turning humans into cold-blooded ectotherms via adenosine receptors 156
Inhibition of nicotinamide phosphoribosyltransferase: cellular bioenergetics reveals a mitochondrial insensitive NAD pool 155
Long-Term Treatment Over 52 Weeks with Monthly Fremanezumab in Drug-Resistant Migraine: A Prospective Multicenter Cohort Study 154
Intrinsic mechanisms of poly(ADP-ribose) neurotoxicity: three hypotheses. 153
Pharmacological NAD-boosting strategies improve mitochondrial homeostasis in human complex i-mutant fibroblastss 152
Tryptophan availability selectively limits NO-synthase induction in macrophages. 151
Studies on the pharmacological properties of oxindole (2-hydroxyindole) and 5-hydroxyindole: are they involved in hepatic encephalopathy? 151
Poly(ADP-ribose) accumulation and enhancement of postischemic brain damage in 110-kDa poly(ADP-ribose) glycohydrolase null mice. 151
High expression of indoleamine 2,3-dioxygenase gene in prostate cancer. 150
PARP-1 inhibition prevents CNS migration of dendritic cells during EAE, suppressing the encephalitogenic response and relapse severity 150
Cuprizone-Dependent De/Remyelination Responses and Functional Correlates in Mouse Strains Adopted to Model Relapsing, Chronic and Progressive Experimental Autoimmune Encephalomyelitis 150
Poly(ADP-ribosyl)ation regulates heat shock factor-1 activity and the heat shock response in murine fibroblasts 149
A snapshot of chemoresistance to PARP inhibitors 149
Opportunities for the repurposing of PARP inhibitors for the therapy of non-oncological diseases 148
Induction of CD83+ CD14+ non-dendritic antigen-presenting cells by exposure of monocytes to IFN-alpha1 148
Working Towards an Appropriate Use of Ibuprofen in Children: An Evidence-Based Appraisal 148
Effect of prolonged incubation with copper on endothelium-dependent relaxation in rat isolated aorta. 147
Mental pain and pain-proneness in migraine subjects: Results from the PAINMIG cohort-study 145
KYNURENINE DISPOSITION IN BLOOD AND BRAIN OF MICE: EFFECTS OF SELECTIVE INHIBITORS OF KYNURENINE HYDROXYLASE AND OF KYNURENINASE 145
Expression of indoleamine 2,3-dioxygenase induced by IFN-γ and TNF-α as potential biomarker of prostate cancer progression 145
Comparison of the neurochemical and behavioral effects resulting from the inhibition of kynurenine hydroxylase and/or kynureninase. 144
Totale 18.466
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Categoria #
all - tutte 73.751
article - articoli 0
book - libri 0
conference - conferenze 0
curatela - curatele 0
other - altro 0
patent - brevetti 0
selected - selezionate 0
volume - volumi 0
Totale 73.751
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Totale Lug Ago Sett Ott Nov Dic Gen Feb Mar Apr Mag Giu
2021/20221.041 28 86 71 28 45 71 35 75 56 64 160 322
2022/20232.765 257 487 114 203 187 458 336 137 240 27 83 236
2023/2024905 48 108 165 58 76 81 45 170 20 51 56 27
2024/20256.857 255 691 447 1.012 1.894 736 169 502 317 285 250 299
2025/20268.628 908 1.088 624 496 899 323 987 509 607 576 343 1.268
2026/2027217 217 0 0 0 0 0 0 0 0 0 0 0
Totale 26.454