CHIARUGI, ALBERTO
 Distribuzione geografica
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Continente #
NA - Nord America 12.279
EU - Europa 6.431
AS - Asia 5.199
SA - Sud America 631
AF - Africa 124
OC - Oceania 93
Continente sconosciuto - Info sul continente non disponibili 2
Totale 24.759
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Nazione #
US - Stati Uniti d'America 12.168
RU - Federazione Russa 2.484
SG - Singapore 1.434
CN - Cina 1.326
PL - Polonia 925
HK - Hong Kong 836
IT - Italia 750
IE - Irlanda 588
VN - Vietnam 519
BR - Brasile 500
SE - Svezia 462
KR - Corea 446
FR - Francia 247
DE - Germania 210
CH - Svizzera 206
FI - Finlandia 171
GB - Regno Unito 156
IN - India 147
AU - Australia 93
BD - Bangladesh 90
UA - Ucraina 89
TR - Turchia 83
CA - Canada 66
JP - Giappone 66
JO - Giordania 56
NL - Olanda 55
AR - Argentina 44
ID - Indonesia 41
CI - Costa d'Avorio 34
MX - Messico 32
EC - Ecuador 27
PK - Pakistan 27
IQ - Iraq 24
ZA - Sudafrica 19
ES - Italia 18
BE - Belgio 16
NG - Nigeria 15
CL - Cile 13
UZ - Uzbekistan 12
PY - Paraguay 11
VE - Venezuela 11
AE - Emirati Arabi Uniti 10
MA - Marocco 10
PE - Perù 10
CO - Colombia 9
EG - Egitto 9
LT - Lituania 9
PH - Filippine 9
SA - Arabia Saudita 9
TN - Tunisia 9
BJ - Benin 8
NP - Nepal 8
RO - Romania 8
IL - Israele 7
TW - Taiwan 6
UY - Uruguay 6
AT - Austria 5
KE - Kenya 5
MY - Malesia 5
AM - Armenia 4
DK - Danimarca 4
DZ - Algeria 4
HU - Ungheria 4
OM - Oman 4
PT - Portogallo 4
AZ - Azerbaigian 3
IR - Iran 3
KG - Kirghizistan 3
KW - Kuwait 3
KZ - Kazakistan 3
LU - Lussemburgo 3
MU - Mauritius 3
TH - Thailandia 3
BG - Bulgaria 2
BY - Bielorussia 2
CR - Costa Rica 2
ET - Etiopia 2
HN - Honduras 2
HR - Croazia 2
JM - Giamaica 2
LB - Libano 2
LV - Lettonia 2
MM - Myanmar 2
MT - Malta 2
PS - Palestinian Territory 2
RS - Serbia 2
AL - Albania 1
BB - Barbados 1
BH - Bahrain 1
BZ - Belize 1
DO - Repubblica Dominicana 1
EE - Estonia 1
EU - Europa 1
GD - Grenada 1
GE - Georgia 1
GT - Guatemala 1
LA - Repubblica Popolare Democratica del Laos 1
LK - Sri Lanka 1
MD - Moldavia 1
MO - Macao, regione amministrativa speciale della Cina 1
Totale 24.747
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Città #
Santa Clara 2.106
Ashburn 1.477
Fairfield 1.244
Singapore 1.042
Warsaw 916
Hong Kong 704
Chandler 621
Dublin 587
Woodbridge 586
Seattle 548
Cambridge 518
Seoul 442
Houston 428
Wilmington 393
San Jose 381
Beijing 299
Hefei 265
Bern 205
Buffalo 198
Ann Arbor 193
Altamura 163
Lauterbourg 162
Lawrence 162
Los Angeles 159
Princeton 149
Ho Chi Minh City 148
Jacksonville 138
The Dalles 125
Hanoi 119
Medford 110
Council Bluffs 109
Florence 109
Mumbai 96
Moscow 91
Melbourne 90
Boardman 89
Dearborn 87
New York 87
Boston 82
San Diego 74
Shanghai 72
Dallas 65
Izmir 64
Munich 64
Tokyo 59
Chicago 55
Kent 53
São Paulo 47
Milan 44
Paris 42
Rome 40
London 36
Abidjan 34
Jakarta 34
Norwalk 33
Helsinki 30
Orem 29
Clifton 28
Toronto 26
Da Nang 25
Falls Church 25
Dong Ket 24
Redondo Beach 24
Haiphong 22
Turku 22
Frankfurt am Main 21
Hillsboro 20
Guangzhou 18
Rio de Janeiro 18
Phoenix 17
Brussels 16
Abuja 15
Denver 15
Belo Horizonte 14
Johannesburg 14
Yubileyny 14
Andover 13
Bologna 13
Portsmouth 13
Salt Lake City 13
Tianjin 13
Amsterdam 12
Bengaluru 12
Lahore 12
Lappeenranta 12
Montreal 12
Naples 12
Quito 12
Turin 12
Brooklyn 11
Tashkent 11
Baghdad 10
Biên Hòa 10
Nanjing 10
Prato 10
Shenzhen 10
Tappahannock 10
Atlanta 9
Chennai 9
Hangzhou 9
Totale 16.951
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Nome #
Activation of the histaminergic H3 receptor induces phosphorylation of the Akt/GSK-3 beta pathway in cultured cortical neurons and protects against neurotoxic insults. 319
Insight into molecular and functional properties of NMNAT3 reveals new hints of NAD homeostasis within human mitochondria 298
Interplay between histone acetylation/deacetylation and poly(ADPribosyl)ation in the development of ischemic tolerance in vitro 288
Long-Term Effectiveness of Three Anti-CGRP Monoclonal Antibodies in Resistant Chronic Migraine Patients Based on the MIDAS score 266
1B-DMT1(-)IRE Expression During Brain Ischemia Contributes to Cell Death Mediated by NF-kB/RelA Acetylation at Lys310 263
Dexpramipexole improves bioenergetics and outcome in experimental stroke 254
Comparison of the Anti-Inflammatory and Cytotoxic Potential of Different Corticosteroid Eye Drop Preparations 243
Trigeminal ganglion transcriptome analysis in 2 rat models of medication-overuse headache reveals coherent and widespread induction of pronociceptive gene expression patterns 230
Neuroimmunological characterization of a mouse model of primary progressive experimental autoimmune encephalomyelitis and effects of immunosuppressive or neuroprotective strategies on disease evolution 228
A key role for poly(ADP-ribose) polymerase-1 activity during human dendritic cell maturation. 221
Repurposing of dexpramipexole to treatment of neonatal hypoxic/ischemic encephalopathy 215
Identification of the Nicotinamide Salvage Pathway as a New Toxification Route for Antimetabolites 208
Early derangement of axonal mitochondria occurs in a mouse model of progressive but not relapsing-remitting multiple sclerosis 207
The NAD metabolome - a key determinant of cancer cell biology. 204
Enhanced dissolution, permeation and oral bioavailability of aripiprazole mixed micelles: In vitro and in vivo evaluation 204
Indoleamine 2,3-dioxygenase+ cells correspond to the BDCA2+ plasmacytoid dendritic cells in human melanoma sentinel nodes 202
CoQ10-containing eye drops prevent UVB-induced cornea cell damage and increase cornea wound healing by preserving mitochondrial function 202
Dexpramipexole enhances hippocampal synaptic plasticity and memory in the rat 202
Increase in the level of proinflammatory cytokine hmgb1 in nasal fluids of patients with rhinitis and its sequestration by glycyrrhizin induces eosinophil cell death 199
Mono-galloyl glucose derivatives are potent poly(ADP-ribose) glycohydrolase (PARG) inhibitors and partially reduce PARP-1-dependent cell death 198
Recent Advances in Pediatric Use of Oral Paracetamol in Fever and Pain Management 196
Aspetti clinico - terapeutici delle patologie vitreoretiniche. 195
The TRPA1 channel mediates the analgesic action of dipyrone and pyrazolone derivatives 194
Neurological basis of AMP-dependent thermoregulation and its relevance to central and peripheral hyperthermia. 194
Poly(ADP-ribose) polymerase-1 is a nuclear epigenetic regulator of mitochondrial DNA repair and transcription 192
Dexpramipexole Enhances K+ Currents and Inhibits Cell Excitability in the Rat Hippocampus In Vitro 192
"Simple but not simpler": toward a unified picture of energy requirements in cell death. 190
Increased Lacrimal Fluid Level of HMGB1 in Vernal Keratoconjunctivitis 188
Low-dose methadone for refractory chronic migraine accompanied by medication-overuse headache: a prospective cohort study 188
Switching anti-CGRP(R) monoclonal antibodies in multi-assessed non-responder patients and implications for ineffectiveness criteria: A retrospective cohort study 187
Anticonvulsant effect of AMP by direct activation of adenosine A1 receptor. 187
PARP inhibition delays progression of mitochondrial encephalopathy in mice 187
Long-lasting neuroprotection and neurological improvement in stroke models with new, potent and brain permeable inhibitors of poly(ADP-ribose) polymerase. 186
Practical and clinical utility of non-invasive vagus nerve stimulation (nVNS) for the acute treatment of migraine: A post hoc analysis of the randomized, sham-controlled, double-blind PRESTO trial 185
Pharmacological effects of exogenous NAD on mitochondrial bioenergetics, DNA repair, and apoptosis 185
Mental Pain Questionnaire: Clinimetric Properties of a Potential Global Person‐Centred Outcome Measure 180
Selective PARP-2 inhibitors increase apoptosis in hippocampal slices but protect cortical cells in models of post-ischaemic brain damage. 180
Ischemic Neuroprotection by TRPV1 Receptor-Induced Hypothermia 177
Effects of Class II-Selective Histone Deacetylase Inhibitor on Neuromuscular Function and Disease Progression in SOD1-ALS Mice 176
Aspetti clinico-terapeutici delle patologie vitreoretiniche. Ediz. illustrata 175
BID mediates neuronal cell death after oxygen/ glucose deprivation and focal cerebral ischemia. 175
Neurological basis of AMP-dependent thermoregulation and its relevance to central and peripheral hyperthermia 175
Validation of the Italian version of the Cluster Headache Impact Questionnaire (CHIQ) 173
Effects of cluster headache preventatives on mouse hypothalamic transcriptional homeostasis 173
Effect of Class II HDAC inhibition on glutamate transporter expression and survival in SOD1-ALS mice 172
Dexamethasone promotes a stem-like phenotype in human melanoma cells via tryptophan 2,3 dioxygenase 172
Histone Deacetylase (HDAC) Inhibitors Reduce the Glial Inflammatory Response In Vitro and In Vivo 171
Glucose deprivation converts poly(ADP-ribose) polymerase-1 hyperactivation into a transient energy-producing process. 171
Nicotinamide phosphoribosyltransferase (NAMPT) activity is essential for survival of resting lymphocytes 171
Post onset, oral rapamycin treatment delays development of mitochondrial encephalopathy only at supramaximal doses 170
Inhibitors of kynurenine hydroxylase and kynureninase increase cerebral formation of kynurenate and have sedative and anticonvulsant activities. 166
Acute and chronic triptan exposure neither alters rodent cerebral blood flow nor worsens ischemic brain injury 166
Long-term suppression of EAE relapses by pharmacological impairment of epitope spreading 166
Mild activation of poly(ADP-ribose) polymerase (PARP) is neuroprotective in rat hippocampal slice models of ischemic tolerance 164
Caspase inhibition augments Dichlorvos-induced dopaminergic neuronal cell death by increasing ROS production and PARP1 activation. 164
Poly(ADP-ribose) polymerase is not involved in the neuroprotection exerted by azithromycin against ischemic stroke in mice 164
IDENTIFICATION AND MEASUREMENT OF OXINDOLE (2-INDOLINONE) IN THE MAMMALIAN BRAIN AND OTHER RAT ORGANS 163
Synthesis and release of neurotoxic kynurenine metabolites by human monocyte-derived macrophages. 163
Antidromic vasodilatation and the migraine mechanism 163
Differential effects of the tryptophan metabolite 3-hydroxyanthranilic acid on the proliferation of human CD8+ T cells induced by TCR triggering or homeostatic cytokines. 162
Effectiveness of anti-CGRP monoclonal antibodies on central symptoms of migraine 160
Dysregulation of sphingosine 1 phosphate receptor-1 (S1P1) signaling and regulatory lymphocyte-dependent immunosuppression in a model of post-fingolimod MS rebound. 160
Kynurenine 3-mono-oxygenase activity and neurotoxic kynurenine metabolites increase in the spinal cord of rats with experimental allergic encephalomyelitis. 159
The emerging therapeutic potential of sirtuin-interacting drugs: from cell death to lifespan extension. 159
Carboxymethyl beta-glucan binds to corneal epithelial cells and increases cell adhesion to laminin and resistance to oxidative stress. 159
Succinate dehydrogenase subunit B mutations modify human neuroblastoma cell metabolism and proliferation 158
Histone Deacetylase Inhibitors Counteract CGRP Signaling and Pronociceptive Sensitization in a Rat Model of Medication Overuse Headache 157
Studies on the pharmacological properties of oxindole (2-hydroxyindole) and 5-hydroxyindole: are they involved in hepatic encephalopathy? 157
AMP-dependent hypothermia affords protection from ischemic brain injury. 156
Poly(ADP-ribosyl)ation and stroke. 156
Poly(ADP-ribose) catabolism triggers AMP-dependent mitochondrial energy failure 155
Novel isoquinolinone-derived inhibitors of poly(ADP-ribose) polymerase-1: pharmacological characterization and neuroprotective effects in an in vitro model of cerebral ischemia. 154
Functional study in a yeast model of a novel succinate-dehydrogenase subunit B gene germline missense mutation (C191Y) diagnosed in a patient affected by a glomus tumor. 153
18β-glycyrrhetic acid inhibits immune activation triggered by HMGB1, a pro-inflammatory protein found in the tear fluid during conjunctivitis and blepharitis 153
Ultra-rapid brain uptake of subcutaneous sumatriptan in the rat: Implication for cluster headache treatment 153
Therapeutic hypothermia: Turning humans into cold-blooded ectotherms via adenosine receptors 152
Dexpramipexole blocks Nav1.8 sodium channels and provides analgesia in multiple nociceptive and neuropathic pain models 152
Long-Term Treatment Over 52 Weeks with Monthly Fremanezumab in Drug-Resistant Migraine: A Prospective Multicenter Cohort Study 151
Update on the pathophysiology and treatment of rhinogenic headache: Focus on the ibuprofen/pseudoephedrine combination 149
High expression of indoleamine 2,3-dioxygenase gene in prostate cancer. 148
Predictors of sustained response and effects of the discontinuation of anti-calcitonin gene related peptide antibodies and reinitiation in resistant chronic migraine 148
Poly (ADP-ribose) polymerase inhibitors attenuate necrotic but not apoptotic neuronal death in experimental models of cerebral ischemia 147
Working Towards an Appropriate Use of Ibuprofen in Children: An Evidence-Based Appraisal 147
Inhibition of nicotinamide phosphoribosyltransferase: cellular bioenergetics reveals a mitochondrial insensitive NAD pool 146
A snapshot of chemoresistance to PARP inhibitors 143
Comparison of the neurochemical and behavioral effects resulting from the inhibition of kynurenine hydroxylase and/or kynureninase. 143
Induction of CD83+ CD14+ non-dendritic antigen-presenting cells by exposure of monocytes to IFN-alpha1 142
Poly(ADP-ribose) accumulation and enhancement of postischemic brain damage in 110-kDa poly(ADP-ribose) glycohydrolase null mice. 142
Studies on the pharmacological properties of oxindole (2-hydroxyindole) and 5-hydroxyindole: are they involved in hepatic encephalopathy? 141
On the way to selective PARP-2 inhibitors. Design, synthesis, and preliminary evaluation of a series of isoquinolinone derivatives. 139
Expression of indoleamine 2,3-dioxygenase induced by IFN-γ and TNF-α as potential biomarker of prostate cancer progression 138
Neuroprotective effects of propofol in models of cerebral ischemia: inhibition of mitochondrial swelling as a possible mechanism. 137
Similarities and differences in the neuronal death processes activated by 3OH-kynurenine and quinolinic acid. 137
Pharmacological NAD-boosting strategies improve mitochondrial homeostasis in human complex i-mutant fibroblastss 137
Mental pain and pain-proneness in migraine subjects: Results from the PAINMIG cohort-study 137
KYNURENINE DISPOSITION IN BLOOD AND BRAIN OF MICE: EFFECTS OF SELECTIVE INHIBITORS OF KYNURENINE HYDROXYLASE AND OF KYNURENINASE 137
INHIBITION OF POLY(ADP-RIBOSE) GLYCOHYDROLASE BY GALLOTANNIN SELECTIVELY UP-REGULATES EXPRESSION OF PRO-INFLAMMATORY GENES. 136
Poly(ADP-ribosyl)ation regulates heat shock factor-1 activity and the heat shock response in murine fibroblasts 135
Neuroprotection induced by dexpramipexole delays disease progression in a mouse model of progressive multiple sclerosis 135
Intrinsic mechanisms of poly(ADP-ribose) neurotoxicity: three hypotheses. 135
Totale 17.652
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Categoria #
all - tutte 68.731
article - articoli 0
book - libri 0
conference - conferenze 0
curatela - curatele 0
other - altro 0
patent - brevetti 0
selected - selezionate 0
volume - volumi 0
Totale 68.731
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Totale Lug Ago Sett Ott Nov Dic Gen Feb Mar Apr Mag Giu
2020/2021183 0 0 0 0 0 0 0 0 0 0 84 99
2021/20221.041 28 86 71 28 45 71 35 75 56 64 160 322
2022/20232.765 257 487 114 203 187 458 336 137 240 27 83 236
2023/2024905 48 108 165 58 76 81 45 170 20 51 56 27
2024/20256.857 255 691 447 1.012 1.894 736 169 502 317 285 250 299
2025/20267.338 908 1.088 624 496 899 323 987 509 607 576 321 0
Totale 24.947