CHIARUGI, ALBERTO
 Distribuzione geografica
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Continente #
NA - Nord America 11.071
EU - Europa 6.014
AS - Asia 4.047
SA - Sud America 564
OC - Oceania 93
AF - Africa 87
Continente sconosciuto - Info sul continente non disponibili 2
Totale 21.878
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Nazione #
US - Stati Uniti d'America 10.990
RU - Federazione Russa 2.467
SG - Singapore 1.159
CN - Cina 1.013
PL - Polonia 921
HK - Hong Kong 801
IT - Italia 610
IE - Irlanda 582
BR - Brasile 462
SE - Svezia 457
KR - Corea 442
CH - Svizzera 206
DE - Germania 190
VN - Vietnam 184
FI - Finlandia 149
GB - Regno Unito 141
IN - India 129
FR - Francia 96
AU - Australia 93
UA - Ucraina 86
TR - Turchia 82
JO - Giordania 52
CA - Canada 47
NL - Olanda 45
ID - Indonesia 38
AR - Argentina 37
CI - Costa d'Avorio 32
JP - Giappone 30
BD - Bangladesh 28
MX - Messico 27
EC - Ecuador 23
BE - Belgio 16
ZA - Sudafrica 16
ES - Italia 14
IQ - Iraq 14
PK - Pakistan 14
CL - Cile 9
MA - Marocco 9
BJ - Benin 8
PY - Paraguay 8
VE - Venezuela 8
LT - Lituania 7
PE - Perù 7
CO - Colombia 6
EG - Egitto 6
IL - Israele 6
TN - Tunisia 6
UZ - Uzbekistan 6
AE - Emirati Arabi Uniti 5
RO - Romania 5
SA - Arabia Saudita 5
AM - Armenia 4
AT - Austria 4
PH - Filippine 4
TW - Taiwan 4
UY - Uruguay 4
IR - Iran 3
KW - Kuwait 3
LU - Lussemburgo 3
MY - Malesia 3
NP - Nepal 3
OM - Oman 3
AZ - Azerbaigian 2
BY - Bielorussia 2
ET - Etiopia 2
JM - Giamaica 2
KE - Kenya 2
KG - Kirghizistan 2
LB - Libano 2
MT - Malta 2
MU - Mauritius 2
PS - Palestinian Territory 2
PT - Portogallo 2
AL - Albania 1
BG - Bulgaria 1
BZ - Belize 1
DK - Danimarca 1
DO - Repubblica Dominicana 1
DZ - Algeria 1
EE - Estonia 1
EU - Europa 1
GD - Grenada 1
HN - Honduras 1
HR - Croazia 1
HU - Ungheria 1
LA - Repubblica Popolare Democratica del Laos 1
LK - Sri Lanka 1
LV - Lettonia 1
MD - Moldavia 1
MM - Myanmar 1
NI - Nicaragua 1
NO - Norvegia 1
SC - Seychelles 1
TG - Togo 1
TH - Thailandia 1
TZ - Tanzania 1
XK - ???statistics.table.value.countryCode.XK??? 1
Totale 21.878
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Città #
Santa Clara 2.079
Fairfield 1.241
Ashburn 1.079
Warsaw 914
Singapore 802
Hong Kong 675
Chandler 621
Woodbridge 585
Dublin 582
Seattle 547
Cambridge 517
Seoul 440
Houston 422
Wilmington 391
Beijing 282
Hefei 265
Bern 205
Ann Arbor 193
Buffalo 188
Altamura 161
Lawrence 160
Princeton 148
Los Angeles 139
Jacksonville 137
San Jose 119
Medford 109
Florence 98
Mumbai 92
Melbourne 90
Moscow 89
Boardman 88
Dearborn 87
Boston 80
The Dalles 75
San Diego 71
Izmir 64
Munich 64
Shanghai 60
Ho Chi Minh City 55
Kent 51
New York 49
Chicago 46
Dallas 46
São Paulo 46
Paris 39
London 36
Milan 34
Hanoi 33
Norwalk 33
Abidjan 32
Jakarta 32
Rome 30
Clifton 28
Falls Church 25
Tokyo 25
Dong Ket 24
Redondo Beach 24
Toronto 23
Turku 22
Lauterbourg 21
Hillsboro 20
Brussels 16
Council Bluffs 16
Rio de Janeiro 16
Orem 14
Phoenix 14
Yubileyny 14
Andover 13
Portsmouth 13
Salt Lake City 13
Bengaluru 12
Johannesburg 12
Frankfurt am Main 11
Helsinki 11
Belo Horizonte 10
Brooklyn 10
Denver 10
Guangzhou 10
Quito 10
Tappahannock 10
Bologna 9
Lappeenranta 9
Laurel 9
Nanjing 9
Turin 9
Amsterdam 8
Centro 8
Cotonou 8
Düsseldorf 8
Elk Grove Village 8
Lahore 8
Montreal 8
Naples 8
Porto Alegre 8
San Francisco 8
West Jordan 8
Biên Hòa 7
Brescia 7
Mexico City 7
Poplar 7
Totale 15.129
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Nome #
Activation of the histaminergic H3 receptor induces phosphorylation of the Akt/GSK-3 beta pathway in cultured cortical neurons and protects against neurotoxic insults. 302
Insight into molecular and functional properties of NMNAT3 reveals new hints of NAD homeostasis within human mitochondria 286
Interplay between histone acetylation/deacetylation and poly(ADPribosyl)ation in the development of ischemic tolerance in vitro 274
1B-DMT1(-)IRE Expression During Brain Ischemia Contributes to Cell Death Mediated by NF-kB/RelA Acetylation at Lys310 245
Long-Term Effectiveness of Three Anti-CGRP Monoclonal Antibodies in Resistant Chronic Migraine Patients Based on the MIDAS score 239
Dexpramipexole improves bioenergetics and outcome in experimental stroke 225
Comparison of the Anti-Inflammatory and Cytotoxic Potential of Different Corticosteroid Eye Drop Preparations 221
Neuroimmunological characterization of a mouse model of primary progressive experimental autoimmune encephalomyelitis and effects of immunosuppressive or neuroprotective strategies on disease evolution 208
Trigeminal ganglion transcriptome analysis in 2 rat models of medication-overuse headache reveals coherent and widespread induction of pronociceptive gene expression patterns 207
Repurposing of dexpramipexole to treatment of neonatal hypoxic/ischemic encephalopathy 203
A key role for poly(ADP-ribose) polymerase-1 activity during human dendritic cell maturation. 200
Indoleamine 2,3-dioxygenase+ cells correspond to the BDCA2+ plasmacytoid dendritic cells in human melanoma sentinel nodes 192
Identification of the Nicotinamide Salvage Pathway as a New Toxification Route for Antimetabolites 192
Early derangement of axonal mitochondria occurs in a mouse model of progressive but not relapsing-remitting multiple sclerosis 189
The NAD metabolome - a key determinant of cancer cell biology. 188
Dexpramipexole enhances hippocampal synaptic plasticity and memory in the rat 185
Poly(ADP-ribose) polymerase-1 is a nuclear epigenetic regulator of mitochondrial DNA repair and transcription 184
Increase in the level of proinflammatory cytokine hmgb1 in nasal fluids of patients with rhinitis and its sequestration by glycyrrhizin induces eosinophil cell death 184
Mono-galloyl glucose derivatives are potent poly(ADP-ribose) glycohydrolase (PARG) inhibitors and partially reduce PARP-1-dependent cell death 183
Neurological basis of AMP-dependent thermoregulation and its relevance to central and peripheral hyperthermia. 180
CoQ10-containing eye drops prevent UVB-induced cornea cell damage and increase cornea wound healing by preserving mitochondrial function 179
Recent Advances in Pediatric Use of Oral Paracetamol in Fever and Pain Management 179
Long-lasting neuroprotection and neurological improvement in stroke models with new, potent and brain permeable inhibitors of poly(ADP-ribose) polymerase. 177
"Simple but not simpler": toward a unified picture of energy requirements in cell death. 176
Anticonvulsant effect of AMP by direct activation of adenosine A1 receptor. 175
The TRPA1 channel mediates the analgesic action of dipyrone and pyrazolone derivatives 175
Increased Lacrimal Fluid Level of HMGB1 in Vernal Keratoconjunctivitis 170
Low-dose methadone for refractory chronic migraine accompanied by medication-overuse headache: a prospective cohort study 170
Selective PARP-2 inhibitors increase apoptosis in hippocampal slices but protect cortical cells in models of post-ischaemic brain damage. 169
PARP inhibition delays progression of mitochondrial encephalopathy in mice 169
Pharmacological effects of exogenous NAD on mitochondrial bioenergetics, DNA repair, and apoptosis 169
Ischemic Neuroprotection by TRPV1 Receptor-Induced Hypothermia 167
Switching anti-CGRP(R) monoclonal antibodies in multi-assessed non-responder patients and implications for ineffectiveness criteria: A retrospective cohort study 165
Aspetti clinico - terapeutici delle patologie vitreoretiniche. 163
Enhanced dissolution, permeation and oral bioavailability of aripiprazole mixed micelles: In vitro and in vivo evaluation 163
Histone Deacetylase (HDAC) Inhibitors Reduce the Glial Inflammatory Response In Vitro and In Vivo 161
Neurological basis of AMP-dependent thermoregulation and its relevance to central and peripheral hyperthermia 161
Effects of Class II-Selective Histone Deacetylase Inhibitor on Neuromuscular Function and Disease Progression in SOD1-ALS Mice 161
Mild activation of poly(ADP-ribose) polymerase (PARP) is neuroprotective in rat hippocampal slice models of ischemic tolerance 160
BID mediates neuronal cell death after oxygen/ glucose deprivation and focal cerebral ischemia. 159
Practical and clinical utility of non-invasive vagus nerve stimulation (nVNS) for the acute treatment of migraine: A post hoc analysis of the randomized, sham-controlled, double-blind PRESTO trial 159
Aspetti clinico-terapeutici delle patologie vitreoretiniche. Ediz. illustrata 158
Poly(ADP-ribose) polymerase is not involved in the neuroprotection exerted by azithromycin against ischemic stroke in mice 158
Effect of Class II HDAC inhibition on glutamate transporter expression and survival in SOD1-ALS mice 158
Glucose deprivation converts poly(ADP-ribose) polymerase-1 hyperactivation into a transient energy-producing process. 157
Nicotinamide phosphoribosyltransferase (NAMPT) activity is essential for survival of resting lymphocytes 157
IDENTIFICATION AND MEASUREMENT OF OXINDOLE (2-INDOLINONE) IN THE MAMMALIAN BRAIN AND OTHER RAT ORGANS 155
Inhibitors of kynurenine hydroxylase and kynureninase increase cerebral formation of kynurenate and have sedative and anticonvulsant activities. 155
Dexpramipexole Enhances K+ Currents and Inhibits Cell Excitability in the Rat Hippocampus In Vitro 155
Post onset, oral rapamycin treatment delays development of mitochondrial encephalopathy only at supramaximal doses 154
Acute and chronic triptan exposure neither alters rodent cerebral blood flow nor worsens ischemic brain injury 154
Kynurenine 3-mono-oxygenase activity and neurotoxic kynurenine metabolites increase in the spinal cord of rats with experimental allergic encephalomyelitis. 152
Long-term suppression of EAE relapses by pharmacological impairment of epitope spreading 151
Validation of the Italian version of the Cluster Headache Impact Questionnaire (CHIQ) 150
Differential effects of the tryptophan metabolite 3-hydroxyanthranilic acid on the proliferation of human CD8+ T cells induced by TCR triggering or homeostatic cytokines. 150
Dysregulation of sphingosine 1 phosphate receptor-1 (S1P1) signaling and regulatory lymphocyte-dependent immunosuppression in a model of post-fingolimod MS rebound. 150
Antidromic vasodilatation and the migraine mechanism 149
The emerging therapeutic potential of sirtuin-interacting drugs: from cell death to lifespan extension. 149
Carboxymethyl beta-glucan binds to corneal epithelial cells and increases cell adhesion to laminin and resistance to oxidative stress. 148
Dexamethasone promotes a stem-like phenotype in human melanoma cells via tryptophan 2,3 dioxygenase 148
Poly(ADP-ribose) catabolism triggers AMP-dependent mitochondrial energy failure 147
Succinate dehydrogenase subunit B mutations modify human neuroblastoma cell metabolism and proliferation 147
AMP-dependent hypothermia affords protection from ischemic brain injury. 146
Caspase inhibition augments Dichlorvos-induced dopaminergic neuronal cell death by increasing ROS production and PARP1 activation. 146
Synthesis and release of neurotoxic kynurenine metabolites by human monocyte-derived macrophages. 144
Studies on the pharmacological properties of oxindole (2-hydroxyindole) and 5-hydroxyindole: are they involved in hepatic encephalopathy? 144
Therapeutic hypothermia: Turning humans into cold-blooded ectotherms via adenosine receptors 144
Histone Deacetylase Inhibitors Counteract CGRP Signaling and Pronociceptive Sensitization in a Rat Model of Medication Overuse Headache 143
Effects of cluster headache preventatives on mouse hypothalamic transcriptional homeostasis 141
Poly (ADP-ribose) polymerase inhibitors attenuate necrotic but not apoptotic neuronal death in experimental models of cerebral ischemia 140
Functional study in a yeast model of a novel succinate-dehydrogenase subunit B gene germline missense mutation (C191Y) diagnosed in a patient affected by a glomus tumor. 140
18β-glycyrrhetic acid inhibits immune activation triggered by HMGB1, a pro-inflammatory protein found in the tear fluid during conjunctivitis and blepharitis 140
Poly(ADP-ribosyl)ation and stroke. 139
High expression of indoleamine 2,3-dioxygenase gene in prostate cancer. 138
A snapshot of chemoresistance to PARP inhibitors 137
Update on the pathophysiology and treatment of rhinogenic headache: Focus on the ibuprofen/pseudoephedrine combination 137
Ultra-rapid brain uptake of subcutaneous sumatriptan in the rat: Implication for cluster headache treatment 137
Mental Pain Questionnaire: Clinimetric Properties of a Potential Global Person‐Centred Outcome Measure 136
Novel isoquinolinone-derived inhibitors of poly(ADP-ribose) polymerase-1: pharmacological characterization and neuroprotective effects in an in vitro model of cerebral ischemia. 135
Inhibition of nicotinamide phosphoribosyltransferase: cellular bioenergetics reveals a mitochondrial insensitive NAD pool 134
Poly(ADP-ribose) accumulation and enhancement of postischemic brain damage in 110-kDa poly(ADP-ribose) glycohydrolase null mice. 133
Dexpramipexole blocks Nav1.8 sodium channels and provides analgesia in multiple nociceptive and neuropathic pain models 133
Effectiveness of anti-CGRP monoclonal antibodies on central symptoms of migraine 132
Tryptophan availability selectively limits NO-synthase induction in macrophages. 131
Long-Term Treatment Over 52 Weeks with Monthly Fremanezumab in Drug-Resistant Migraine: A Prospective Multicenter Cohort Study 130
Expression of indoleamine 2,3-dioxygenase induced by IFN-γ and TNF-α as potential biomarker of prostate cancer progression 129
Intrinsic mechanisms of poly(ADP-ribose) neurotoxicity: three hypotheses. 128
On the way to selective PARP-2 inhibitors. Design, synthesis, and preliminary evaluation of a series of isoquinolinone derivatives. 128
Studies on the pharmacological properties of oxindole (2-hydroxyindole) and 5-hydroxyindole: are they involved in hepatic encephalopathy? 127
Brain ischemic preconditioning does not require PARP-1 127
Induction of CD83+ CD14+ non-dendritic antigen-presenting cells by exposure of monocytes to IFN-alpha1 127
Poly(ADP-ribosyl)ation regulates heat shock factor-1 activity and the heat shock response in murine fibroblasts 126
KYNURENINE DISPOSITION IN BLOOD AND BRAIN OF MICE: EFFECTS OF SELECTIVE INHIBITORS OF KYNURENINE HYDROXYLASE AND OF KYNURENINASE 126
Poly(ADP-ribose) polymerase as a key player in excitotoxicity and post-ischemic brain damage 126
Predictors of sustained response and effects of the discontinuation of anti-calcitonin gene related peptide antibodies and reinitiation in resistant chronic migraine 126
Neuroprotection induced by dexpramipexole delays disease progression in a mouse model of progressive multiple sclerosis 125
INHIBITION OF POLY(ADP-RIBOSE) GLYCOHYDROLASE BY GALLOTANNIN SELECTIVELY UP-REGULATES EXPRESSION OF PRO-INFLAMMATORY GENES. 125
Comparison of the neurochemical and behavioral effects resulting from the inhibition of kynurenine hydroxylase and/or kynureninase. 124
Working Towards an Appropriate Use of Ibuprofen in Children: An Evidence-Based Appraisal 123
Effect of prolonged incubation with copper on endothelium-dependent relaxation in rat isolated aorta. 122
Totale 16.085
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Categoria #
all - tutte 61.498
article - articoli 0
book - libri 0
conference - conferenze 0
curatela - curatele 0
other - altro 0
patent - brevetti 0
selected - selezionate 0
volume - volumi 0
Totale 61.498
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Totale Lug Ago Sett Ott Nov Dic Gen Feb Mar Apr Mag Giu
2020/2021685 0 0 0 0 0 0 47 116 131 208 84 99
2021/20221.032 28 86 71 28 45 67 35 75 53 64 159 321
2022/20232.755 256 483 114 202 187 456 335 137 240 26 83 236
2023/2024900 48 108 164 58 76 81 45 170 20 49 54 27
2024/20256.819 254 688 442 1.008 1.882 730 168 502 313 284 250 298
2025/20264.492 904 1.084 622 495 896 321 170 0 0 0 0 0
Totale 22.039