MASSAI, LARA
 Distribuzione geografica
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Continente #
NA - Nord America 7.082
EU - Europa 4.027
AS - Asia 3.071
SA - Sud America 355
Continente sconosciuto - Info sul continente non disponibili 176
AF - Africa 79
OC - Oceania 29
Totale 14.819
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Nazione #
US - Stati Uniti d'America 6.918
RU - Federazione Russa 1.132
IT - Italia 986
PL - Polonia 869
CN - Cina 847
SG - Singapore 828
HK - Hong Kong 463
VN - Vietnam 308
BR - Brasile 274
KR - Corea 246
IE - Irlanda 207
SE - Svezia 142
NL - Olanda 138
DE - Germania 124
FR - Francia 113
FI - Finlandia 112
GB - Regno Unito 104
CA - Canada 100
IN - India 75
BD - Bangladesh 73
JP - Giappone 41
ID - Indonesia 40
JO - Giordania 34
AU - Australia 28
AR - Argentina 27
MX - Messico 26
ES - Italia 23
NG - Nigeria 18
UA - Ucraina 17
ZA - Sudafrica 17
BE - Belgio 16
EC - Ecuador 16
IQ - Iraq 16
VE - Venezuela 16
TR - Turchia 15
CI - Costa d'Avorio 13
CH - Svizzera 10
JM - Giamaica 10
PK - Pakistan 8
SA - Arabia Saudita 8
CO - Colombia 7
MA - Marocco 7
RO - Romania 7
BH - Bahrain 6
CL - Cile 6
PH - Filippine 6
AE - Emirati Arabi Uniti 5
AT - Austria 5
CR - Costa Rica 5
IL - Israele 5
MY - Malesia 5
UZ - Uzbekistan 5
AL - Albania 4
EE - Estonia 4
IR - Iran 4
KE - Kenya 4
AZ - Azerbaigian 3
CZ - Repubblica Ceca 3
DO - Repubblica Dominicana 3
DZ - Algeria 3
EG - Egitto 3
HN - Honduras 3
KG - Kirghizistan 3
KZ - Kazakistan 3
NI - Nicaragua 3
PE - Perù 3
PS - Palestinian Territory 3
PY - Paraguay 3
TH - Thailandia 3
TW - Taiwan 3
BB - Barbados 2
BJ - Benin 2
GD - Grenada 2
GT - Guatemala 2
KH - Cambogia 2
LT - Lituania 2
NP - Nepal 2
OM - Oman 2
PT - Portogallo 2
SN - Senegal 2
SY - Repubblica araba siriana 2
TN - Tunisia 2
UY - Uruguay 2
AM - Armenia 1
AO - Angola 1
AW - Aruba 1
BO - Bolivia 1
BS - Bahamas 1
BW - Botswana 1
BY - Bielorussia 1
CY - Cipro 1
DK - Danimarca 1
ET - Etiopia 1
GA - Gabon 1
GE - Georgia 1
GP - Guadalupe 1
HT - Haiti 1
HU - Ungheria 1
IS - Islanda 1
KW - Kuwait 1
Totale 14.628
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Città #
Santa Clara 1.270
Ashburn 966
Warsaw 864
Singapore 576
Fairfield 430
Hong Kong 412
San Jose 308
Seoul 243
Woodbridge 231
Chandler 219
Hefei 207
Dublin 206
Florence 199
Houston 181
Beijing 177
Seattle 176
Milan 161
Cambridge 159
Council Bluffs 140
Los Angeles 134
Wilmington 133
Ann Arbor 121
New York 120
Buffalo 103
Ho Chi Minh City 92
Amsterdam 81
Lauterbourg 79
Lawrence 77
Rome 77
Altamura 71
Dallas 70
Princeton 64
Hanoi 62
Munich 49
Chicago 47
Helsinki 44
The Dalles 44
Moscow 43
Groningen 42
Boston 38
Phoenix 36
Tokyo 36
Shanghai 34
Bologna 31
Kent 31
Mumbai 30
Turku 30
Medford 28
Melbourne 28
São Paulo 27
Jakarta 26
Naples 26
Toronto 26
Clifton 25
Orem 25
San Diego 24
Da Nang 22
London 22
Boardman 20
Jacksonville 19
Turin 19
Abuja 18
Brooklyn 17
Paris 17
Montreal 16
Brussels 15
Mexico City 15
Palermo 15
Abidjan 13
Atlanta 13
Barcelona 13
Denver 13
Figino 13
Redondo Beach 13
Haiphong 12
Bristol 11
Frankfurt am Main 11
Guangzhou 11
The Bronx 11
Bengaluru 10
Charlotte 10
Stockholm 10
West Jordan 10
Baghdad 9
Belo Horizonte 9
Campinas 9
Lappeenranta 9
Philadelphia 9
Tianjin 9
Washington 9
Chennai 8
Dong Ket 8
Falkenstein 8
Johannesburg 8
Norwalk 8
Pistoia 8
Poplar 8
Rio de Janeiro 8
Verona 8
Wuhan 8
Totale 9.711
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Nome #
The leading established metal-based drugs: a revisitation of their relevant physico-chemical data 673
Gold Compounds as Anticancer Agents: A Systematic Study of Gold–Protein Metalation 368
A first-in-class and a fished out anticancer platinum compound:: Cis -[PtCl2(NH3)2] and cis -[PtI2(NH3)2] compared for their reactivity towards DNA model systems 351
Antiproliferative effects of two gold(I)-N-heterocyclic carbene complexes in A2780 human ovarian cancer cells: A comparative proteomic study 350
Reactions of model proteins with aurothiomalate, a clinically established gold(I) drug: The comparison with auranofin 332
Proteomic analysis of A2780/S ovarian cancer cell response to the cytotoxic organogold(III) compound Aubipy(c.) 331
Proteomic analysis of the cytotoxic effects induced by the organogold(III) complex Aubipyc in cisplatin-resistant A2780 ovarian cancer cells: further evidence for the glycolytic pathway implication 313
Evidence that the antiproliferative effects of auranofin in Saccharomyces cerevisiae arise from inhibition of mitochondrial respiration 294
Design, synthesis and characterisation of new chimeric ruthenium(ii)-gold(i) complexes as improved cytotoxic agents 282
Selection and characterization of a human ovarian cancer cell line resistant to auranofin 263
Replacement of the Thiosugar of Auranofin with Iodide Enhances the Anticancer Potency in a Mouse Model of Ovarian Cancer 262
Chemistry and Biology of Two Novel Gold(I) Carbene Complexes as Prospective Anticancer Agents 257
Determinants for Tight and Selective Binding of a Medicinal Dicarbene Gold(I) Complex to a Telomeric DNA G-Quadruplex: a Joint ESI MS and XRD Investigation 252
Anticancer effects against colorectal cancer models of chloro(triethylphosphine)gold(I) encapsulated in PLGA–PEG nanoparticles 235
Cytotoxic properties of a new organometallic platinum(II) complex and its gold(I) heterobimetallic derivatives. 228
Antiproliferative properties and biomolecular interactions of three Pd(II) and Pt(II) complexes 219
[Au(9-methylcaffein-8-ylidene)2]+/DNA Tel23 System: Solution, Computational, and Biological Studies 218
Elucidating the reactivity of Pt(II) complexes with (O,S) bidentate ligands towards DNA model systems 203
Structural and solution chemistry, antiproliferative effects, and serum albumin binding of three pseudohalide derivatives of auranofin 202
Au2phen and Auoxo6, Two Dinuclear Oxo-Bridged Gold({III}) Compounds, Induce Apoptotic Signaling in Human Ovarian A2780 Cancer Cells 202
Chemistry and biology of three representative gold(III) compounds as prospective anticancer agents 197
Bioconjugation of the gold drug auranofin to human ferritin yields a potent cytotoxin 195
Interactions of the organogold(III) compound Aubipyc with the copper chaperone Atox1: A joint mass spectrometry and circular dichroism investigation 185
Pyrene-Containing Polyamines as Fluorescent Receptors for Recognition of PFOA in Aqueous Media 184
The mode of action of anticancer gold-based drugs: a structural perspective 184
Protonation of cyclen-based chelating agents containing fluorescent moieties 184
Interaction of anticancer Ru(III) complexes with single stranded and duplex DNA model systems 183
Gold compounds: new anticancer drugs candidates. Studies of protein metalation processes 181
Large Protein Assemblies for High-Relaxivity Contrast Agents: The Case of Gadolinium-Labeled Asparaginase 179
Gold-Based Metal Drugs as Inhibitors of Coronavirus Proteins: The Inhibition of SARS-CoV-2 Main Protease by Auranofin and Its Analogs 179
Chemical Modification of Auranofin Yields a New Family of Anticancer Drug Candidates: The Gold(I) Phosphite Analogues 179
Anticancer Ruthenium(III) Complex KP1019 Interferes with ATP-Dependent Ca(2+) Translocation by Sarco-Endoplasmic Reticulum Ca(2+) -ATPase (SERCA) 178
Organogold(III) compounds as experimental anticancer agents: chemical and biological profiles 177
Cisplatin binding to human serum albumin: a structural study 177
Comparative NMR metabolomics of the responses of A2780 human ovarian cancer cells to clinically established Pt-based drugs 172
Interactions of Gold-based drugs with proteins: crystal structure of the adduct formed between Ribonuclease A and a cytotoxic gold(III) compound 171
Protein Metalation by Medicinal Gold Compounds: Identification of the Main Features of the Metalation Process through ESI MS Experiments 168
The effects of two gold-N-heterocyclic carbene (NHC) complexes in ovarian cancer cells: a redox proteomic study 167
Size dependent biological profiles of PEGylated gold nanorods 167
Cyclodextrin Inclusion Complexes of Auranofin and Its Iodido Analog: A Chemical and Biological Study 166
The effects of two cytotoxic gold(i) carbene compounds on the metabolism of A2780 ovarian cancer cells: mechanistic inferences through NMR analysis 162
Interactions of selected gold(III) complexes with DNA G quadruplexes 162
Reactions of Cytotoxic Metallodrugs with Lysozyme in pure DMSO explored through UV-Vis Absorption Spectroscopy and ESI MS 159
The cisplatin/serum albumin system: A reappraisal 157
19F: A small probe for a giant protein 157
Protein metalation by metal-based drugs: reactions of cytotoxic gold compounds with cytochrome c and lysozyme 154
Cell and Cell-Free Mechanistic Studies on Two Gold(III) Complexes with Proven Antitumor Properties 154
Inhibition of Na+/K+-ATPase and cytotoxicity of a few selected gold(III) complexes 144
Studies of cytotoxic gold compounds: interactions with model proteins and with the copper chaperone Atox-1 141
Direct detection of iron clusters in L ferritins through ESI-MS experiments 140
Selected Cytotoxic Gold Compounds cause Significant Inhibition of 20S Proteasome Catalytic Activities 138
Platinum(II) Complexes with O,S Bidentate Ligands: Biophysical Characterization, Antiproliferative Activity, and Crystallographic Evidence of Protein Binding 137
NMR reveals the metabolic changes induced by auranofin in A2780 cancer cells: Evidence for glutathione dysregulation 136
Reactions of Medicinal Gold(III) Compounds With Proteins and Peptides Explored by Electrospray Ionization Mass Spectrometry and Complementary Biophysical Methods 133
Mercury binding to proteins disclosed by ESI MS experiments: The case of three organomercurials 133
Structure-activity relationships in a series of auranofin analogues showing remarkable antiproliferative properties 131
Mechanistic studies on cytotoxic gold compounds 129
Gold compounds as cysteine protease inhibitors: perspectives for pharmaceutical application as antiparasitic agents 128
Dirhodium tetraacetate binding to a B-DNA double helical dodecamer probed by X-ray crystallography and mass spectrometry 126
Na/K-ATPase as a target for anticancer metal based drugs: insights into molecular interactions with selected gold(iii) complexes 126
Unlocking the Power of Human Ferritin: Enhanced Drug Delivery of Aurothiomalate in A2780 Ovarian Cancer Cells 126
Structural evidences for a secondary gold binding site in the hydrophobic box of lysozyme 125
Proteomics as a tool to disclose the cellular and molecular mechanisms of selected anticancer gold compounds 125
Strategies for the design of analogs of auranofin endowed with anticancer potential 124
Antiproliferative Properties of a Few Auranofin-Related Gold(I) and Silver(I) Complexes in Leukemia Cells and their Interferences with the Ubiquitin Proteasome System 124
Deciphering the role of neutral diruthenium complexes in protein binding 121
Medicinal gold compounds form tight adducts with the copper chaperone Atox-1: biological and pharmacological implications 121
On the mechanism of action of arsenoplatins: arsenoplatin-1 binding to a B-DNA dodecamer 115
Cytotoxic Pt(ii) complexes containing alizarin: a selective carrier for DNA metalation 110
Novel NMR-Based Approach to Reveal the ‘Metabolic Fingerprint’ of Cytotoxic Gold Drugs in Cancer Cells 107
Auranofin and its analogs as prospective agents for the treatment of colorectal cancer 97
Reactions of proteins with a few organopalladium compounds of medicinal interest 89
Synthesis, chemical characterization, and biological evaluation of a novel auranofin derivative as an anticancer agent 87
Reactions of Medicinal Gold Compounds with Cathepsin B Explored through Electrospray Mass Spectrometry Measurements 86
Picoplatin binding to proteins: X-ray structures and mass spectrometry data on the adducts with lysozyme and ribonuclease A 82
Enlarging the scenario of site directed 19F labeling for NMR spectroscopy of biomolecules 81
null 68
Cytotoxicity and Binding to DNA, Lysozyme, Ribonuclease A, and Human Serum Albumin of the Diiodido Analog of Picoplatin 64
Oxaliplatin bioconjugates with human ferritin obtained by protein surface decoration: Characterization and biological evaluation 61
Editorial: The Golden Future in Medicinal Chemistry: Perspectives and Resources From Old and New Gold-Based Drug Candidates 50
Lipoic acid as a linker to auranofin analogue on nanocellulose 47
Antiproliferative properties of a few auranofin-related Gold(I) and Silver(I) complexes in leukemia cells and their interferences with the ubiquitin proteasome system 47
Playing with Structural Parameters in the Design of Ruthenium(II)-p-Cymene Complexes as Potential Antibacterial Agents 45
The impact of albumin conjugation on the cytotoxic properties of cisplatin, oxaliplatin and auranofin in cancer cells 38
Modeling the metabolic response of A2780 ovarian cancer cells to gold-based cytotoxic drugs 37
New platinum(II) and palladium(II) complexes with substituted terpyridine ligands: synthesis and characterization, cytotoxicity and reactivity towards biomolecules 36
Reactions with proteins of three novel anticancer platinum(II) complexes bearing N-heterocyclic ligands 33
Protein metalation by metal-based drugs: Reactions of cytotoxic gold compounds with cytochrome c and lysozyme 31
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Comparative reactivity of medicinal gold(i) compounds with the cyclic peptide vasopressin and its diselenide analogue 30
Medicinal Au(i) compounds targeting urease as prospective antimicrobial agents: unveiling the structural basis for enzyme inhibition 29
Medicinal gold compounds form tight adducts with the copper chaperone Atox-1: Biological and pharmacological implications 26
Protein metalation by two structurally related gold(I) carbene complexes: An ESI MS study 26
Ligand-driven redox behavior of gold(III) complexes: electrochemical insights into stability and biological potential 25
Reactions of Arsenoplatin-1 with Protein Targets: A Combined Experimental and Theoretical Study (2022) Inorganic Chemistry 24
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Lipoic acid as a linker to Auranofin analogue on nanocellulose 19
The electrochemical profiles of Auranofin and Aubipyc, two representative medicinal gold compounds: A comparative study 19
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Conjugates of gold nanoparticles and antitumor gold(III) complexes as a tool for their AFM and SERS detection in biological tissue 17
Totale 14.817
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Categoria #
all - tutte 40.709
article - articoli 0
book - libri 0
conference - conferenze 0
curatela - curatele 0
other - altro 0
patent - brevetti 0
selected - selezionate 0
volume - volumi 0
Totale 40.709
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Totale Lug Ago Sett Ott Nov Dic Gen Feb Mar Apr Mag Giu
2021/2022355 0 0 0 16 17 23 13 35 25 24 88 114
2022/2023983 97 219 65 70 57 166 127 43 91 10 23 15
2023/2024509 19 38 74 23 34 62 33 119 15 35 20 37
2024/20253.522 117 302 204 437 1.029 500 76 278 163 76 145 195
2025/20265.508 496 625 473 392 514 166 551 324 407 330 694 536
2026/20271.137 231 111 403 392 0 0 0 0 0 0 0 0
Totale 14.819