MORONI, FLAVIO
 Distribuzione geografica
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Continente #
NA - Nord America 17.259
EU - Europa 10.054
AS - Asia 6.507
SA - Sud America 843
OC - Oceania 168
AF - Africa 157
Continente sconosciuto - Info sul continente non disponibili 12
Totale 35.000
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Nazione #
US - Stati Uniti d'America 17.102
RU - Federazione Russa 3.356
IT - Italia 1.997
SG - Singapore 1.905
CN - Cina 1.292
HK - Hong Kong 1.203
PL - Polonia 988
IE - Irlanda 941
SE - Svezia 941
VN - Vietnam 711
BR - Brasile 686
KR - Corea 554
DE - Germania 355
FI - Finlandia 343
FR - Francia 312
UA - Ucraina 299
TR - Turchia 246
GB - Regno Unito 208
IN - India 175
AU - Australia 168
CH - Svizzera 147
CA - Canada 93
JP - Giappone 75
JO - Giordania 68
BD - Bangladesh 57
IQ - Iraq 47
AR - Argentina 46
NL - Olanda 35
ZA - Sudafrica 34
CI - Costa d'Avorio 33
MX - Messico 31
BE - Belgio 29
ID - Indonesia 29
PK - Pakistan 29
EC - Ecuador 26
ES - Italia 23
CO - Colombia 20
NG - Nigeria 20
PH - Filippine 16
RO - Romania 15
SA - Arabia Saudita 15
VE - Venezuela 15
PE - Perù 14
PY - Paraguay 14
CL - Cile 12
SC - Seychelles 11
EG - Egitto 10
KE - Kenya 10
TN - Tunisia 10
UZ - Uzbekistan 10
AT - Austria 9
AZ - Azerbaigian 9
BG - Bulgaria 9
CR - Costa Rica 9
EU - Europa 9
MA - Marocco 8
PT - Portogallo 8
DK - Danimarca 7
LB - Libano 7
LT - Lituania 7
MY - Malesia 7
BY - Bielorussia 6
NP - Nepal 6
TW - Taiwan 6
UY - Uruguay 6
AE - Emirati Arabi Uniti 5
SN - Senegal 5
ET - Etiopia 4
GT - Guatemala 4
HN - Honduras 4
IL - Israele 4
NI - Nicaragua 4
OM - Oman 4
AM - Armenia 3
CZ - Repubblica Ceca 3
DO - Repubblica Dominicana 3
DZ - Algeria 3
HU - Ungheria 3
IR - Iran 3
JM - Giamaica 3
KW - Kuwait 3
KZ - Kazakistan 3
NO - Norvegia 3
TH - Thailandia 3
AO - Angola 2
BA - Bosnia-Erzegovina 2
BJ - Benin 2
BO - Bolivia 2
GY - Guiana 2
HR - Croazia 2
KH - Cambogia 2
LU - Lussemburgo 2
PS - Palestinian Territory 2
QA - Qatar 2
SY - Repubblica araba siriana 2
XK - ???statistics.table.value.countryCode.XK??? 2
BQ - ???statistics.table.value.countryCode.BQ??? 1
CG - Congo 1
CM - Camerun 1
GD - Grenada 1
Totale 34.984
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Città #
Santa Clara 2.976
Fairfield 1.758
Ashburn 1.682
Singapore 1.334
Chandler 1.075
Warsaw 985
Hong Kong 979
Dublin 941
Woodbridge 802
Cambridge 716
Seattle 698
Houston 627
Wilmington 613
Jacksonville 550
Seoul 548
Milan 375
San Jose 359
Beijing 353
Buffalo 331
Ann Arbor 308
Lawrence 280
Altamura 270
The Dalles 269
Los Angeles 266
Princeton 264
Lauterbourg 236
Boardman 205
Rome 199
Ho Chi Minh City 195
Medford 176
Melbourne 162
Izmir 158
Hefei 156
Hanoi 153
Bern 143
Boston 140
Mumbai 116
San Diego 108
Florence 98
Moscow 88
Shanghai 84
Dong Ket 82
New York 81
Munich 70
Tokyo 68
São Paulo 66
Helsinki 64
Dallas 58
Naples 55
Bologna 52
Norwalk 52
Turin 50
Dearborn 47
Paris 41
Kent 40
Hillsboro 36
London 36
Da Nang 35
Toronto 35
Abidjan 33
Guangzhou 32
Palermo 32
Falls Church 31
Redondo Beach 31
Verona 31
Brussels 29
Orem 28
Frankfurt am Main 25
Chicago 24
Council Bluffs 23
Figino 23
Rio de Janeiro 23
Turku 23
West Jordan 23
Yubileyny 23
Haiphong 21
Portsmouth 21
Venice 21
Tianjin 20
Abuja 19
Baghdad 18
Brooklyn 18
Genoa 17
Johannesburg 17
Phoenix 17
Belo Horizonte 16
Frankfurt Am Main 16
Washington 16
Andover 15
Auburn Hills 15
Catania 15
Jakarta 15
Miano 15
Shenzhen 15
Bari 14
Cagliari 14
Denver 14
Modena 14
Curitiba 12
Padua 12
Totale 23.585
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Nome #
GPR35 Activation Reduces Ca2+ Transients and Contributes to the Kynurenic Acid-Dependent Reduction of Synaptic Activity at CA3-CA1 Synapses 383
The Inhibitory Effects of HYDAMTIQ, a Novel PARP Inhibitor, on Growth in Human Tumor Cell Lines With Defective DNA Damage Response Pathways. 340
Arrays of MicroLEDs and Astrocytes: Biological Amplifiers to Optogenetically Modulate Neuronal Networks Reducing Light Requirement 338
Differential role of mGlu1 and mGlu5 receptors in rat hippocampal slice models of ischemic tolerance 305
Interplay between histone acetylation/deacetylation and poly(ADPribosyl)ation in the development of ischemic tolerance in vitro 291
Group I metabotropic glutamate receptors stimulate the activity of poly(ADP-ribose) polymerase in mammalian mGlu1-transfected cells and in cortical cell cultures. 286
HCV Patients Psychopathology and Tryptophan Metabolism: Analysis of the Effects of Pegylated Interferon plus Ribavirin Treatment 259
Glutamate Receptor-Mediated Neurotoxicity in a Model of Ethanol Dependence and Withdrawal in Rat Organotypic Hippocampal Slice Cultures 258
HYDAMTIQ, a selective PARP-1 inhibitor, improves bleomycin-induced lung fibrosis by dampening the TGF-β/SMAD signalling pathway 250
Methadone Dose Adjustments, Plasma R-Methadone Levels and Therapeutic Outcome of Heroin Users: A Randomized Clinical Trial 246
Kynurenic acid: a metabolite with multiple actions and multiple targets in brain and periphery. 242
Differential role of poly(ADP-ribose) polymerase-1 in apoptotic and necrotic neuronal death induced by mild or intense NMDA exposure in vitro 237
G-protein coupled receptor 35 (GPR35) activation and inflammatory pain: Studies on the antinociceptive effects of kynurenic acid and zaprinast 236
5-HYDROXYINDOLE CAUSES CONVULSIONS AND INCREASES TRANSMITTER RELEASE IN THE CA1 REGION OF RAT HIPPOCAMPUS 233
A key role for poly(ADP-ribose) polymerase-1 activity during human dendritic cell maturation. 230
Kynurenic acid and zaprinast induce analgesia by modulating HCN channels through GPR35 activation 226
Activation of mGlu1 but not mGlu5 metabotropic glutamate receptors contributes to post-ischemic neuronal injury in vitro and in vivo. 207
Mono-galloyl glucose derivatives are potent poly(ADP-ribose) glycohydrolase (PARG) inhibitors and partially reduce PARP-1-dependent cell death 206
Ethanol Toxicity During Brain Development: Alterations of Excitatory Synaptic Transmission in Immature Organotypic Hippocampal Slice Cultures 200
Biochemical and electrophysiological studies on (S)-(+)-2-(3'- carboxybicyclo[1.1.1]pentyl)-glycine (CBPG), a novel mGlu5 receptor agonist endowed with mGlu1 receptor antagonist activity. 199
Neurological basis of AMP-dependent thermoregulation and its relevance to central and peripheral hyperthermia. 199
Poly(ADP-ribose) polymerase-1 is a nuclear epigenetic regulator of mitochondrial DNA repair and transcription 197
Adenosine decreases aspartate and glutamate release from rat hippocampal slices. 196
Peripheral and Splanchnic Indole and Oxindole Levels in Cirrhotic Patients: A Study on the Pathophysiology of Hepatic Encephalopathy 195
Pharmacological effects of exogenous NAD on mitochondrial bioenergetics, DNA repair, and apoptosis 192
Acute cyanide intoxication treated with a combination of hydroxycobalamin, sodium nitrite, and sodium thiosulfate. 192
Long-lasting neuroprotection and neurological improvement in stroke models with new, potent and brain permeable inhibitors of poly(ADP-ribose) polymerase. 190
PARP-1 activation causes neuronal death in the hippocampal CA1 region by increasing the expression of Ca2+-permeable AMPA receptors 190
Poly(ADP-ribose) polymerase inhibition with HYDAMTIQ reduces allergen-induced asthma-like reaction, bronchial hyper-reactivity and airway remodelling. 188
8-phenyltheophylline potentiates the evoked electrical activity in hippocampal slices. 187
Selective PARP-2 inhibitors increase apoptosis in hippocampal slices but protect cortical cells in models of post-ischaemic brain damage. 187
Biochemical and behavioural studies on indole-pyruvic acid: a keto-analogue of tryptophan. 186
Neurological basis of AMP-dependent thermoregulation and its relevance to central and peripheral hyperthermia 186
CB1 receptors and post-ischemic brain damage: studies on the toxic and neuroprotective effects of cannabinoids in rat organotypic hippocampal slices 185
1-Amino-1,5-dicarboxylic acid and (S)-(+)-2-(3'-carboxybicyclo[1.1.1]pentyl)-glycine, two mGlu1 receptor-preferring antagonists, reduce neuronal death in in vitro and in vivo models of cerebral ischemia 182
Ischemic Neuroprotection by TRPV1 Receptor-Induced Hypothermia 182
Differential mechanisms of tolerance induced by NMDA and DHPG preconditioning 181
Kynurenic acid inhibits the release of the neurotrophic fibroblast growth factor (FGF)-1 and enhances proliferation of glia cells, in vitro. 179
Histone Deacetylase (HDAC) Inhibitors Reduce the Glial Inflammatory Response In Vitro and In Vivo 178
Modulation of the spontaneous histamine release by adrenergic and cholinergic drugs 176
Ammonium acetate inhibits ionitropic receptors and differentially affects metabotropic receptors for glutamate 175
A new endogenous anxiolytic agent: L-pyroglutamic acid. 175
Low serum tryptophan levels, reduced macrophage IDO activity and high frequency of psychopathology in HCV patients 174
Rat hippocampal slice culture models for the evaluation of neuroprotective agents. 174
Kynurenine 3-mono-oxygenase activity and neurotoxic kynurenine metabolites increase in the spinal cord of rats with experimental allergic encephalomyelitis. 172
Levels and synthesis of glutamate and aspartate in the olfactory cortex following bulbectomy. 171
Mild activation of poly(ADP-ribose) polymerase (PARP) is neuroprotective in rat hippocampal slice models of ischemic tolerance 171
Pharmacological characterization of metabotropic glutamate receptors potentiating NMDA responses in mouse cortical wedge preparations 171
Calcium channel inhibitors suppress the morphine-withdrawal syndrome in rats. 170
Increase in the content of quinolinic acid in cerebrospinal fluid and frontal cortex of patients with hepatic failure. 170
Inhibitors of kynurenine hydroxylase and kynureninase increase cerebral formation of kynurenate and have sedative and anticonvulsant activities. 169
Sulfate esters of hydroxy amino acids as stereospecific glutamate receptor agonists. 169
Carboxymethyl beta-glucan binds to corneal epithelial cells and increases cell adhesion to laminin and resistance to oxidative stress. 169
Tryptophan/kynurenine pathway changes in HCV-infected patients: possible involvement in associated neuropsychiatry pathology 168
The release of endogenous GABA and glutamate from the cerebral cortex in the rat. 167
Neuroprotection by group I mGlu receptors in a rat hippocampal slice model of cerebral ischemia is associated with the PI3K–Akt signaling pathway: A novel postconditioning strategy? 166
Involvement of endocannabinoid signaling in the neuroprotective effects of subtype 1 metabotropic glutamate receptor antagonists in models of cerebral ischemia 166
Interazioni farmacologiche nella terapia moderna. Farmaci e salute 147-153, 1975. 165
Presynaptic kynurenate-sensitive receptors inhibit glutamate release. 165
IDENTIFICATION AND MEASUREMENT OF OXINDOLE (2-INDOLINONE) IN THE MAMMALIAN BRAIN AND OTHER RAT ORGANS 164
Synthesis and release of neurotoxic kynurenine metabolites by human monocyte-derived macrophages. 163
18β-glycyrrhetic acid inhibits immune activation triggered by HMGB1, a pro-inflammatory protein found in the tear fluid during conjunctivitis and blepharitis 163
1-Methyl-4-Phenylpyridinium (Mpp+) Modulates Hyperpolarization-Activated Current (Ih) In Substantia Nigra Pars Compacta Dopaminergic Neurons 163
DHPG and NMDA preconditioning induce ischemic tolerance with differential mechanisms 163
Interplay between group I mGlu and the endocannabinoid system in the hippocampus: studies in models of cerebral ischemia 163
1-Aminoindan-1,5-dicarboxylic acid: a novel antagonist at phospholipase C-linked metabotropic glutamate receptors. 163
Studies on the pharmacological properties of oxindole (2-hydroxyindole) and 5-hydroxyindole: are they involved in hepatic encephalopathy? 162
(+)MCPG induces PKC-epsilon translocation in cortical synaptosomes through a PLD-coupled mGluR 161
General anaesthetics inhibit the responses induced by glutamate receptor agonists in the mouse cortex. 160
Kynurenine hydroxylase inhibitors reduce ischemic brain damage: studies with (m-nitrobenzoyl)-alanine (mNBA) and 3,4-dimethoxy-[-N-4-(nitrophenyl)thiazol-2yl]-benzenesulfonamide (Ro 61-8048) in models of focal or global brain ischemia. 160
Poly (ADP-ribose) polymerase inhibitors attenuate necrotic but not apoptotic neuronal death in experimental models of cerebral ischemia 159
Poly(ADP-ribose)polymerase 1 (PARP-1) and postischemic brain damage. 159
In vitro cell growth inhibitory effects of HYDAMTIQ, a novel PARP inhibitor, on human tumor cell lines with defective DNA damage response pathways 158
GPR35 is functionally expressed in astrocytes and mediates kynurenic acid-dependent reduction of excitatory synaptic activity at CA3-CA1 synapse. 158
Comet assay as a novel approach for studying DNA damage in focal cerebral ischemia: differential effects of NMDA receptor antagonists and poly(ADP-ribose) polymerase inhibitors 158
Erythropoietin attenuates post-traumatic injury in organotypic hippocampal slices 157
Increase in kynurenic acid in Huntington's disease motor cortex. 156
Poly(ADP-ribose) catabolism triggers AMP-dependent mitochondrial energy failure 156
The excitotoxin quinolinic acid is present and unevenly distributed in the rat brain. 154
An electrophysiological study of the mGlu1 receptors ability to modulate endocannabinoids production and inhibitory synaptic transmission in the CA1 hippocampal area 154
Inhibition of nicotinamide phosphoribosyltransferase: cellular bioenergetics reveals a mitochondrial insensitive NAD pool 153
Acute changes of blood ammonia may predict short-term adverse effects of valproic acid. 152
Studies on the pharmacological properties of oxindole (2-hydroxyindole) and 5-hydroxyindole: are they involved in hepatic encephalopathy? 151
Poly(ADP-ribose) accumulation and enhancement of postischemic brain damage in 110-kDa poly(ADP-ribose) glycohydrolase null mice. 151
Tryptophan availability selectively limits NO-synthase induction in macrophages. 150
(2R, 1’S, 2’R, 3’S)-2-(2’-Carboxy-3’-phenylcyclopropyl)glycine (PCCG-13), the first potent and selective competitive antagonist of PLD-coupled metabotropic receptors. Asymmetric synthesis and preliminary biological reports. 150
PARP-1 inhibition prevents CNS migration of dendritic cells during EAE, suppressing the encephalitogenic response and relapse severity 150
Erratum: The inhibitory effects of HYDAMTIQ, a novel PARP inhibitor, on growth in human tumor cell lines with defective DNA damage response pathways (Oncology Research 25:9 (1441-1451) DOI: 10.3727/096504017X14926854178616) 150
Pharmacological characterization of metabotropic glutamate receptors coupled to phospholipase D in the rat hippocampus 149
Release of glutamate from striatum of freely moving rats by pros-methylimidazoleacetic acid 149
Poly(ADP-ribosyl)ation regulates heat shock factor-1 activity and the heat shock response in murine fibroblasts 149
Alteration of the subcellular and tissue distribution of ELAV-type proteins during cerebral ischemia in the rat 149
mGlu1 receptors and endocannabinoids: neuroprotection studies in an in vitro model of cerebral ischemia 149
Opportunities for the repurposing of PARP inhibitors for the therapy of non-oncological diseases 147
Kynurenine 3-mono-oxygenase inhibitors reduce glutamate concentration in the extracellular spaces of the basal ganglia but not in those of the cortex or hippocampus 146
The regulation of brain kynurenic acid content: focus on indole-3-pyruvic acid. 146
KYNURENINE DISPOSITION IN BLOOD AND BRAIN OF MICE: EFFECTS OF SELECTIVE INHIBITORS OF KYNURENINE HYDROXYLASE AND OF KYNURENINASE 145
Kynurenic acid is present in the rat brain and its content increases during development and aging processes. 144
Comparison of the neurochemical and behavioral effects resulting from the inhibition of kynurenine hydroxylase and/or kynureninase. 144
On the way to selective PARP-2 inhibitors. Design, synthesis, and preliminary evaluation of a series of isoquinolinone derivatives. 143
Totale 18.468
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Categoria #
all - tutte 98.051
article - articoli 0
book - libri 0
conference - conferenze 0
curatela - curatele 0
other - altro 0
patent - brevetti 0
selected - selezionate 0
volume - volumi 0
Totale 98.051
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Totale Lug Ago Sett Ott Nov Dic Gen Feb Mar Apr Mag Giu
2021/20221.562 45 141 76 93 74 78 57 91 89 74 247 497
2022/20234.434 452 763 146 328 412 833 513 234 410 24 122 197
2023/20241.176 81 175 273 54 87 130 34 203 18 42 46 33
2024/20258.898 334 926 571 1.361 2.691 1.001 138 612 522 228 289 225
2025/20269.669 1.019 1.353 771 387 1.055 415 1.224 557 675 466 184 1.563
2026/2027115 115 0 0 0 0 0 0 0 0 0 0 0
Totale 35.096