MORONI, FLAVIO
 Distribuzione geografica
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Continente #
NA - Nord America 10.772
EU - Europa 4.566
AS - Asia 942
AF - Africa 14
Continente sconosciuto - Info sul continente non disponibili 9
OC - Oceania 5
SA - Sud America 1
Totale 16.309
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Nazione #
US - Stati Uniti d'America 10.743
PL - Polonia 966
IE - Irlanda 941
SE - Svezia 940
IT - Italia 541
HK - Hong Kong 377
UA - Ucraina 288
FI - Finlandia 258
DE - Germania 238
TR - Turchia 220
CN - Cina 156
CH - Svizzera 146
GB - Regno Unito 128
VN - Vietnam 82
JO - Giordania 59
RU - Federazione Russa 30
CA - Canada 29
BE - Belgio 26
FR - Francia 25
SG - Singapore 23
SC - Seychelles 11
RO - Romania 10
EU - Europa 9
ES - Italia 8
IN - India 8
NL - Olanda 8
AU - Australia 5
BG - Bulgaria 5
JP - Giappone 5
KR - Corea 5
DK - Danimarca 3
IR - Iran 2
LU - Lussemburgo 2
TW - Taiwan 2
AT - Austria 1
CM - Camerun 1
CZ - Repubblica Ceca 1
DZ - Algeria 1
ID - Indonesia 1
IL - Israele 1
MU - Mauritius 1
NO - Norvegia 1
SA - Arabia Saudita 1
VE - Venezuela 1
Totale 16.309
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Città #
Fairfield 1.765
Chandler 1.078
Warsaw 966
Dublin 941
Woodbridge 809
Ashburn 785
Cambridge 720
Seattle 702
Houston 621
Wilmington 611
Jacksonville 550
Ann Arbor 314
Lawrence 280
Altamura 270
Princeton 265
Boardman 199
Medford 176
Hong Kong 160
Izmir 158
Bern 144
Boston 127
San Diego 105
Beijing 95
Buffalo 91
Dong Ket 82
Florence 59
Norwalk 53
Dearborn 47
Shanghai 45
Hillsboro 36
Falls Church 31
Milan 30
New York 30
Brussels 26
Toronto 24
West Jordan 22
Los Angeles 19
London 18
Frankfurt Am Main 16
Andover 15
Auburn Hills 15
Washington 14
Verona 11
Singapore 10
Tappahannock 10
Timisoara 10
Laurel 9
Phoenix 8
Rome 8
Saint Petersburg 8
San Mateo 8
Bremen 7
Salerno 7
Barcelona 5
Leawood 5
Redwood City 5
Sofia 5
Bentley 4
Chicago 4
Moscow 4
Piacenza 4
Pune 4
Redmond 4
Bologna 3
Cheongju-si 3
Copenhagen 3
Detroit 3
Hefei 3
Misano Adriatico 3
Nanjing 3
Napoli 3
Ottawa 3
Padova 3
Pisa 3
Augusta 2
Bari 2
Capri 2
Castrocaro Terme 2
Delianuova 2
Düsseldorf 2
Fuzhou 2
Grevenbroich 2
Helsinki 2
Luxembourg 2
Mountain View 2
Nürnberg 2
Romainville 2
Saint Paul 2
Siena 2
Tokyo 2
Wandsworth 2
Águilas 2
Acton 1
Adana 1
Adelaide 1
Akron 1
Anguillara Sabazia 1
Arnsberg 1
Avellino 1
Bartlesville 1
Totale 12.731
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Nome #
GPR35 Activation Reduces Ca2+ Transients and Contributes to the Kynurenic Acid-Dependent Reduction of Synaptic Activity at CA3-CA1 Synapses 230
Group I metabotropic glutamate receptors stimulate the activity of poly(ADP-ribose) polymerase in mammalian mGlu1-transfected cells and in cortical cell cultures. 219
The Inhibitory Effects of HYDAMTIQ, a Novel PARP Inhibitor, on Growth in Human Tumor Cell Lines With Defective DNA Damage Response Pathways. 218
Arrays of MicroLEDs and Astrocytes: Biological Amplifiers to Optogenetically Modulate Neuronal Networks Reducing Light Requirement 214
Differential role of mGlu1 and mGlu5 receptors in rat hippocampal slice models of ischemic tolerance 211
Interplay between histone acetylation/deacetylation and poly(ADPribosyl)ation in the development of ischemic tolerance in vitro 198
Differential role of poly(ADP-ribose) polymerase-1 in apoptotic and necrotic neuronal death induced by mild or intense NMDA exposure in vitro 183
Glutamate Receptor-Mediated Neurotoxicity in a Model of Ethanol Dependence and Withdrawal in Rat Organotypic Hippocampal Slice Cultures 141
Methadone Dose Adjustments, Plasma R-Methadone Levels and Therapeutic Outcome of Heroin Users: A Randomized Clinical Trial 126
Kynurenic acid: a metabolite with multiple actions and multiple targets in brain and periphery. 125
HYDAMTIQ, a selective PARP-1 inhibitor, improves bleomycin-induced lung fibrosis by dampening the TGF-β/SMAD signalling pathway 121
Poly(ADP-ribose) polymerase inhibition with HYDAMTIQ reduces allergen-induced asthma-like reaction, bronchial hyper-reactivity and airway remodelling. 119
Neurological basis of AMP-dependent thermoregulation and its relevance to central and peripheral hyperthermia. 115
Mono-galloyl glucose derivatives are potent poly(ADP-ribose) glycohydrolase (PARG) inhibitors and partially reduce PARP-1-dependent cell death 114
A key role for poly(ADP-ribose) polymerase-1 activity during human dendritic cell maturation. 110
Poly(ADP-ribose)polymerase 1 (PARP-1) and postischemic brain damage. 107
Selective PARP-2 inhibitors increase apoptosis in hippocampal slices but protect cortical cells in models of post-ischaemic brain damage. 105
G-protein coupled receptor 35 (GPR35) activation and inflammatory pain: Studies on the antinociceptive effects of kynurenic acid and zaprinast 104
5-HYDROXYINDOLE CAUSES CONVULSIONS AND INCREASES TRANSMITTER RELEASE IN THE CA1 REGION OF RAT HIPPOCAMPUS 103
Long-lasting neuroprotection and neurological improvement in stroke models with new, potent and brain permeable inhibitors of poly(ADP-ribose) polymerase. 103
Rat hippocampal slice culture models for the evaluation of neuroprotective agents. 103
PARP-1 activation causes neuronal death in the hippocampal CA1 region by increasing the expression of Ca2+-permeable AMPA receptors 101
Poly(ADP-ribose) polymerase-1 is a nuclear epigenetic regulator of mitochondrial DNA repair and transcription 97
Kynurenic acid and zaprinast induce analgesia by modulating HCN channels through GPR35 activation 97
Adenosine decreases aspartate and glutamate release from rat hippocampal slices. 95
Erythropoietin attenuates post-traumatic injury in organotypic hippocampal slices 94
Modulation of the spontaneous histamine release by adrenergic and cholinergic drugs 93
Kynurenine hydroxylase inhibitors reduce ischemic brain damage: studies with (m-nitrobenzoyl)-alanine (mNBA) and 3,4-dimethoxy-[-N-4-(nitrophenyl)thiazol-2yl]-benzenesulfonamide (Ro 61-8048) in models of focal or global brain ischemia. 93
Pharmacological effects of exogenous NAD on mitochondrial bioenergetics, DNA repair, and apoptosis 92
Neuroprotection by group I mGlu receptors in a rat hippocampal slice model of cerebral ischemia is associated with the PI3K–Akt signaling pathway: A novel postconditioning strategy? 91
Studies on the pharmacological properties of oxindole (2-hydroxyindole) and 5-hydroxyindole: are they involved in hepatic encephalopathy? 91
Calcium gluconate and hypertonic sodium chloride in a case of massive verapamil poisoning. 91
On the way to selective PARP-2 inhibitors. Design, synthesis, and preliminary evaluation of a series of isoquinolinone derivatives. 90
Poly (ADP-ribose) polymerase inhibitors attenuate necrotic but not apoptotic neuronal death in experimental models of cerebral ischemia 89
Pharmacological characterization of metabotropic glutamate receptors potentiating NMDA responses in mouse cortical wedge preparations 89
Poly(ADP-ribose) accumulation and enhancement of postischemic brain damage in 110-kDa poly(ADP-ribose) glycohydrolase null mice. 88
Biochemical and electrophysiological studies on (S)-(+)-2-(3'- carboxybicyclo[1.1.1]pentyl)-glycine (CBPG), a novel mGlu5 receptor agonist endowed with mGlu1 receptor antagonist activity. 87
Detection and Pharmacological Modulation of Nicotinamide Mononucleotide (NMN) in vitro and in vivo 87
1-Aminoindan-1,5-dicarboxylic acid: a novel antagonist at phospholipase C-linked metabotropic glutamate receptors. 87
The release of endogenous GABA and glutamate from the cerebral cortex in the rat. 86
Biochemical and behavioural studies on indole-pyruvic acid: a keto-analogue of tryptophan. 86
Release of glutamate from striatum of freely moving rats by pros-methylimidazoleacetic acid 85
Kynurenic acid inhibits the release of the neurotrophic fibroblast growth factor (FGF)-1 and enhances proliferation of glia cells, in vitro. 85
Peripheral and Splanchnic Indole and Oxindole Levels in Cirrhotic Patients: A Study on the Pathophysiology of Hepatic Encephalopathy 85
Mild activation of poly(ADP-ribose) polymerase (PARP) is neuroprotective in rat hippocampal slice models of ischemic tolerance 85
Inhibitors of kynurenine hydroxylase and kynureninase increase cerebral formation of kynurenate and have sedative and anticonvulsant activities. 83
Studies on the pharmacological properties of oxindole (2-hydroxyindole) and 5-hydroxyindole: are they involved in hepatic encephalopathy? 83
IDENTIFICATION AND MEASUREMENT OF OXINDOLE (2-INDOLINONE) IN THE MAMMALIAN BRAIN AND OTHER RAT ORGANS 82
Levels and synthesis of glutamate and aspartate in the olfactory cortex following bulbectomy. 82
KYNURENINE DISPOSITION IN BLOOD AND BRAIN OF MICE: EFFECTS OF SELECTIVE INHIBITORS OF KYNURENINE HYDROXYLASE AND OF KYNURENINASE 82
Pharmacological characterization of metabotropic glutamate receptors coupled to phospholipase D in the rat hippocampus 81
Ethanol Toxicity During Brain Development: Alterations of Excitatory Synaptic Transmission in Immature Organotypic Hippocampal Slice Cultures 81
INHIBITION OF POLY(ADP-RIBOSE) GLYCOHYDROLASE BY GALLOTANNIN SELECTIVELY UP-REGULATES EXPRESSION OF PRO-INFLAMMATORY GENES. 81
Kynurenine 3-mono-oxygenase activity and neurotoxic kynurenine metabolites increase in the spinal cord of rats with experimental allergic encephalomyelitis. 80
Activation of mGlu1 but not mGlu5 metabotropic glutamate receptors contributes to post-ischemic neuronal injury in vitro and in vivo. 80
Poly(ADP-ribosyl)ation regulates heat shock factor-1 activity and the heat shock response in murine fibroblasts 79
Tryptophan availability selectively limits NO-synthase induction in macrophages. 79
Presynaptic kynurenate-sensitive receptors inhibit glutamate release. 79
The regulation of brain kynurenic acid content: focus on indole-3-pyruvic acid. 79
Poly(ADP-ribose) catabolism triggers AMP-dependent mitochondrial energy failure 78
CB1 receptors and post-ischemic brain damage: studies on the toxic and neuroprotective effects of cannabinoids in rat organotypic hippocampal slices 78
Acute cyanide intoxication treated with a combination of hydroxycobalamin, sodium nitrite, and sodium thiosulfate. 78
Sulfate esters of hydroxy amino acids as stereospecific glutamate receptor agonists. 78
1-Amino-1,5-dicarboxylic acid and (S)-(+)-2-(3'-carboxybicyclo[1.1.1]pentyl)-glycine, two mGlu1 receptor-preferring antagonists, reduce neuronal death in in vitro and in vivo models of cerebral ischemia 77
Agonists, antagonists and modulators of excitatory amino acid receptors in the guinea-pig myenteric plexus. 77
Ischemic Neuroprotection by TRPV1 Receptor-Induced Hypothermia 77
Neurological basis of AMP-dependent thermoregulation and its relevance to central and peripheral hyperthermia 77
Poly(ADP-ribose) polymerase as a key player in excitotoxicity and post-ischemic brain damage 77
HCV Patients Psychopathology and Tryptophan Metabolism: Analysis of the Effects of Pegylated Interferon plus Ribavirin Treatment 76
Clinical pharmacokinetics of valproic acid--1988. 76
Increase in the content of quinolinic acid in cerebrospinal fluid and frontal cortex of patients with hepatic failure. 76
Carboxymethyl beta-glucan binds to corneal epithelial cells and increases cell adhesion to laminin and resistance to oxidative stress. 76
Histone Deacetylase (HDAC) Inhibitors Reduce the Glial Inflammatory Response In Vitro and In Vivo 75
Kynurenine 3-mono-oxygenase inhibitors attenuate post-ischemic neuronal death in organotypic hippocampal slice cultures. 75
Stereoselective synthesis and preliminary evaluation of (+)- and (-)-3-methyl-5-carboxy-thien-2-yl-glycine (3-MATIDA): identification of (+)-3-MATIDA as a novel mGluR1 competitive antagonist. 74
Increase in kynurenic acid in Huntington's disease motor cortex. 74
The release and neosynthesis of glutamic acid are increased in experimental models of hepatic encephalopathy. 74
Poly(ADP-Ribose)Polymerase 1 (PARP-1) Activation and Ca(2+) Permeable α-Amino-3-Hydroxy-5-Methyl-4-Isoxazolepropionic Acid (AMPA) Channels in Post-Ischemic Brain Damage: New Therapeutic Opportunities? 74
Comet assay as a novel approach for studying DNA damage in focal cerebral ischemia: differential effects of NMDA receptor antagonists and poly(ADP-ribose) polymerase inhibitors 74
Quinolinic acid formation in immune-activated mice: studies with (m-nitrobenzoyl)-alanine (mNBA) and 3,4-dimethoxy-[-N-4-(-3-nitrophenyl)thiazol-2yl]-benzenesul fonamide (Ro 61-8048), two potent and selective inhibitors of kynurenine hydroxylase. 73
18β-glycyrrhetic acid inhibits immune activation triggered by HMGB1, a pro-inflammatory protein found in the tear fluid during conjunctivitis and blepharitis 73
A new endogenous anxiolytic agent: L-pyroglutamic acid. 73
The novel and systemically active metabotropic glutamate 1 (mGlu1) receptor antagonist 3-MATIDA reduces post-ischemic neuronal death 73
Calcium channel inhibitors suppress the morphine-withdrawal syndrome in rats. 73
Decrease in rat cerebral quinolinic acid concentration following chronic hydrocortisone treatment. 73
TOPICALLY APPLIED MINOXIDIL MAY CAUSE FETAL MALFORMATION: A CASE REPORT 72
Naloxone administration releases catecholamines. 72
PARP-1 inhibition prevents CNS migration of dendritic cells during EAE, suppressing the encephalitogenic response and relapse severity 72
Comparison of the neurochemical and behavioral effects resulting from the inhibition of kynurenine hydroxylase and/or kynureninase. 72
General anaesthetics inhibit the responses induced by glutamate receptor agonists in the mouse cortex. 71
Kynurenic acid is present in the rat brain and its content increases during development and aging processes. 71
Topical Mannitol Reduces Inflammatory Edema in a Rat Model of Arthritis 71
Content of quinolinic acid and of other tryptophan metabolites increases in brain regions of rats used as experimental models of hepatic encephalopathy. 71
Group I metabotropic glutamate receptor inhibition selectively blocks a prolonged Ca2+ elevation associated with age-dependent excitotoxicity 70
8-phenyltheophylline potentiates the evoked electrical activity in hippocampal slices. 69
Metabotropic glutamate 1 (mGlu1) receptor antagonists enhance GABAergic neurotransmission: a mechanism for the attenuation of post-ischemic injury and epileptiform activity? 69
The modulation of kynurenic acid content in the mammalian brain. 69
Similarities and differences in the neuronal death processes activated by 3OH-kynurenine and quinolinic acid. 69
Differential mechanisms of tolerance induced by NMDA and DHPG preconditioning 69
Brain ischemic preconditioning does not require PARP-1 69
Totale 9.379
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Categoria #
all - tutte 43.435
article - articoli 0
book - libri 0
conference - conferenze 0
curatela - curatele 0
other - altro 0
patent - brevetti 0
selected - selezionate 0
volume - volumi 0
Totale 43.435
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Totale Lug Ago Sett Ott Nov Dic Gen Feb Mar Apr Mag Giu
2018/20191.825 0 0 0 0 0 0 0 0 0 349 830 646
2019/20203.733 339 239 106 332 404 478 447 471 381 234 236 66
2020/20212.200 239 151 167 169 46 323 78 172 208 275 160 212
2021/20221.567 45 141 76 93 74 80 57 92 90 74 247 498
2022/20234.450 454 763 146 330 412 836 514 238 410 24 125 198
2023/20241.097 81 176 274 54 87 131 34 203 18 39 0 0
Totale 16.403