Distribuzione geografica
Continente #
NA - Nord America 5.878
EU - Europa 3.999
AS - Asia 532
AF - Africa 16
SA - Sud America 7
Continente sconosciuto - Info sul continente non disponibili 5
OC - Oceania 1
Totale 10.438
Nazione #
US - Stati Uniti d'America 5.867
PL - Polonia 1.676
IE - Irlanda 556
SE - Svezia 551
IT - Italia 412
UA - Ucraina 256
DE - Germania 225
HK - Hong Kong 219
FI - Finlandia 142
CN - Cina 120
GB - Regno Unito 67
JO - Giordania 64
TR - Turchia 52
CH - Svizzera 37
VN - Vietnam 32
SG - Singapore 27
FR - Francia 17
BE - Belgio 16
RU - Federazione Russa 14
ES - Italia 13
SC - Seychelles 13
CA - Canada 9
IN - India 8
NL - Olanda 8
EU - Europa 5
KR - Corea 4
RO - Romania 4
JP - Giappone 3
PT - Portogallo 3
BO - Bolivia 2
BR - Brasile 2
IL - Israele 2
MU - Mauritius 2
AU - Australia 1
BG - Bulgaria 1
BS - Bahamas 1
CL - Cile 1
EC - Ecuador 1
EG - Egitto 1
GR - Grecia 1
ID - Indonesia 1
MX - Messico 1
PE - Perù 1
Totale 10.438
Città #
Warsaw 1.674
Fairfield 932
Chandler 646
Dublin 556
Jacksonville 477
Ashburn 418
Woodbridge 413
Cambridge 353
Seattle 327
Wilmington 305
Houston 297
Ann Arbor 185
Princeton 156
Florence 109
Boardman 108
Hong Kong 96
Boston 93
Medford 84
Beijing 82
Altamura 81
Lawrence 76
Buffalo 66
San Diego 49
Izmir 43
Bern 36
New York 34
Norwalk 33
Falls Church 29
Dong Ket 26
Dearborn 25
Bremen 24
Hillsboro 22
Rome 19
Milan 18
Shanghai 17
Brussels 16
Auburn Hills 13
Singapore 13
Andover 10
Frankfurt Am Main 9
Phoenix 9
Tappahannock 9
Barcelona 8
Toronto 8
Verona 8
Santa Maria A Monte 7
Laurel 6
Salerno 6
Usingen 6
Ankara 4
Chieti 4
Los Angeles 4
Nanjing 4
Redmond 4
Brescia 3
Bursa 3
Evora 3
London 3
Moscow 3
Naaldwijk 3
Redwood City 3
San Mateo 3
Valencia 3
Arezzo 2
Arnsberg 2
Asti 2
Bari 2
Castelliri 2
Fuzhou 2
Guangzhou 2
Hefei 2
Helsinki 2
Jinan 2
La Paz 2
Maletto 2
Modena 2
Nanchang 2
Pune 2
Rostock 2
Saint Petersburg 2
Simi Valley 2
Southwark 2
Timisoara 2
Tokyo 2
Trumbull 2
Venice 2
Amaseno 1
Asbury Park 1
Athens 1
Bagneux 1
Bergamo 1
Cagliari 1
Chiswick 1
Cormeilles-en-Parisis 1
Culiacán 1
Düsseldorf 1
Eastwood 1
Ergolding 1
Fiesole 1
Fossombrone 1
Totale 8.144
Nome #
Oleuropein aglycone induces autophagy via the AMPK/mTOR signalling pathway: A mechanistic insight 240
Oleuropein Aglycone: A Possible Drug against Degenerative Conditions. In Vivo Evidence of its Effectiveness against Alzheimer's Disease 235
The polyphenol oleuropein aglycone protects TgCRND8 mice against Aß plaque pathology 228
Oleuropein aglycone protects against pyroglutamylated-3 amyloid-ß toxicity: biochemical, epigenetic and functional correlates 227
Central cholinergic antinociception induced by 5HT4 agonists: BIMU 1 and BIMU 8 218
Lithium Improves Hippocampal Neurogenesis,Neuropathology and Cognitive Functions in APP MutantMice 217
Young human cholinergic neurons respond to physiological regulators and improve cognitive symptoms in an animal model of Alzheimer’s disease 215
The Brain Cholinergic System in Neurodegenerative Diseases 193
Employing AD animal models for translational research: focus on dietary components 188
Neurodegeneration and the cholinergic system 169
Farmaci per le malattie neurodegenerative 161
Solid lipid nanoparticles for delivery of andrographolide across the blood-brain barrier: in vitro and in vivo evaluation. 158
Different Patterns of Neurodegeneration and Glia Activation in CA1 and CA3 Hippocampal Regions of TgCRND8 Mice 137
The polyphenol oleuropein aglycone modulates the PARP1-SIRT1 interplay: an in vitro and in vivo study 124
Successful Brain Delivery of Andrographolide Loaded in Human Albumin Nanoparticles to TgCRND8 Mice, an Alzheimer’s Disease Mouse Model 124
A New Kid on the Block? Carbonic Anhydrases as Possible New Targets in Alzheimer's Disease 122
Olive oil polyphenols can be useful to prevent aging-associated neurodegeneration 112
Abnormal processing of tau in the brain of aged TgCRND8 mice 103
Changes in cortical acetylcholine output induced by modulation of the nucleus basalis. 100
Clioquinol decreases amyloid-beta burden and reduces working memory impairment in a transgenic mouse model of Alzheimer's disease. 100
Olive polyphenols: new promising agents to combat aging-associated neurodegeneration 99
Development of Blood-Brain Barrier Permeable Nanoparticles as Potential Carriers for Salvianolic Acid B to CNS 97
C-fos expression in the rat nucleus basalis upon excitotoxic lesion with quisqualic acid: a study in adult and aged animals 96
Inhibition of acetylcholine-induced activation of extracellular regulated protein kinase prevents the encoding of an inhibitory avoidance response in the rat 96
Long-term neuro-glial co-cultures as a brain aging model: hallmarks of senescence, miRNA expression profiles and comparison with in vivo models 91
Differential activation of mitogen-activated protein kinase signalling pathways in the hippocampus of CRND8 transgenic mouse, a model of Alzheimer's disease 91
Effect of nerve growth factor and GM1 ganglioside on the recovery of cholinergic neurons after a lesion of the nucleus basalis in aging rats 90
Cholinergic dysfunction, neuronal damage and axonal loss in TgCRND8 mice 89
Amyloid-β oligomer synaptotoxicity is mimicked by oligomers of the model protein HypF-N 87
Increased Dickkopf-1 expression in transgenic mouse models of neurodegenerative disease. 87
A comparison of the biochemical modifications caused by toxic and non-toxic protein oligomers in cells 86
The brain cholinergic system as a target of cognition enhancers 85
The release of endogenous GABA and glutamate from the cerebral cortex in the rat. 84
Effect of phosphatidylserine on acetylcholine output from the cerebral cortex of the rat. 83
Postnatal development of functional properties of visual cortical cells in rats with excitotoxic lesions of basal forebrain cholinergic neurons. 83
An analysis of cholecystokinin-induced increase in acetylcholine output from cerebral cortex of the rat. 82
Aniracetam restores object recognition impaired by age, scopolamine, and nucleus basalis lesions. 82
Oleuropein aglycone and polyphenols from olive mill waste water ameliorate cognitive deficits and neuropathology 82
Effects of 4-aminopyridine on acetylcholine output from the cerebral cortex of the rat in vivo. 81
Changes in presynaptic proteins, SNAP-25 and synaptophysin, in the hippocampal CA1 area in ischemic gerbils. 81
Extracellular chaperones prevent Aβ42-induced toxicity in rat brains 81
Acetylcholine release from fetal tissue homotopically grafted to the motoneuron-depleted lumbar spinal cord. An in vivo microdialysis study in the awake rat. 81
Prefibrillar amyloid aggregates could be generic toxins in higher organisms 81
Brain inflammatory reaction in an animal model of neuronal degeneration and its modulation by an anti-inflammatory drug: implication in Alzheimer's disease. 80
Novel S-acyl glutathione derivatives prevent amyloid oxidative stress and cholinergic dysfunction in Alzheimer disease models. Free Radic Biol Med. 79
The selective cyclooxygenase-2 inhibitor rofecoxib suppresses brain inflammation and protects cholinergic neurons from excitotoxic degeneration in vivo. 78
Effect of thyrotropin releasing hormone (TRH) on acetylcholine release from different brain areas investigated by microdialysis. 78
Acetylcholine release in freely moving rats by means of transversal dialysis coupled to an HPLC with electrochemical detection 77
Poly(ethyl cyanoacrylate) nanoparticles for brain delivery of andrographolide 77
NO-flurbiprofen attenuates excitotoxin-induced brain inflammation, and releases nitric oxide in the brain 76
Activation of brain cholinergic system by noncholinomimetic agents 76
Aging of brain cholinergic neurons: pharmacological interventions. 76
Aβ plaque-associated glial reaction as a determinant of apoptotic neuronal death and cortical gliogenesis: a study in APP mutant mice 75
Combined treatment with atorvastatin and minocycline suppresses severity of EAE 74
Effect of BM-5, a presynaptic antagonist-postsynaptic agonist, on cortical acetylcholine release. 74
Oleuropein aglycone counteracts Aβ42 toxicity in the rat brain 74
Enhanced acetylcholine release in the hippocampus and cortex during acquisition of an operant behavior 73
Lesions of cholinergic forebrain nuclei: changes in avoidance behavior and scopolamine actions. 71
Nerve growth factor increases extracellular acetylcholine levels in the parietal cortex and hippocampus of aged rats and restores object recognition. 70
Long-term ethanol consumption by rats: effect on acetylcholine release in vivo, choline acetyltransferase activity, and behavior. 69
Neutrophils CD11b and fibroblasts PGE2 are elevated in Alzheimer's disease 68
Selective immunolesioning of cholinergic neurons in nucleus basalis magnocellularis impairs prepulse inhibition of acoustic startle. 68
Selective muscarinic antagonists differentially affect in vivo acetylcholine release and memory performances of young and aged rats. 68
Effects of ganglioside treatment in rats with a lesion of the cholinergic forebrain nuclei. 67
Cholinergic dysfunction, neuronal damage and axonal loss in TGCRND8 mice. 67
Interaction between nerve growth factor and GM1 monosialoganglioside in preventing cortical choline acetyltransferase and high affinity choline uptake decrease after lesion of the nucleus basalis. 66
Recovery of cortical acetylcholine output after ganglioside treatment in rats with lesion of the nucleus basalis. 66
Effect of subchronic administration of metrifonate, rivastigmine and donepezil on brain acetylcholine in aged F344 rats. 65
NGF treatment potentiates c-fos expression in the rat nucleus basalis upon excitotoxic lesion with quisqualic acid 64
Unilateral and bilateral nucleus basalis lesions: differences in neurochemical and behavioural recovery. 62
Cellular acetylcholine content and neuronal differentiation 61
Acetylcholine output from the cerebral cortex, choline uptake and muscarinic receptors in morphine dependent freely-moving rats. 61
Amyloid ß-peptides injection into the cholinergic nuclei: Morphological, neurochemical and behavioral effects 59
Immunogenicity and therapeutic efficacy of phage-displayed beta-amyloid epitopes 59
Employing AD animal models for effective translational research 59
Hyperphosphorylation and deposition of tau in the brain of a human APP transgenic mouse model 58
Local cerebral glucose utilization following unilateral and bilateral lesions of the nucleus basalis magnocellularis in the rat. 58
Cholinergic function in the hippocampus of juvenile rats chronically deprived of NGF 56
Decrease of acetylcholine release from cortical slices in aged rats: investigations into its reversal by phosphatidylserine. 56
Effects of novelty and pain on behavior and hippocampal extracellular ACh levels in male and female rats. 55
Neurochemical and behavioural effects following lesions of the nucleus basalis in the rat. 55
Lesions of the globus pallidus: changes in cortical choline acetyltransferase, choline uptake and acetylcholine output in the rat. 54
Cortical and hippocampal ACh release is enhanced by thyrotropin releasing hormone (TRH) in vivo. 54
Effects of nerve growth factor and GM1 ganglioside on the number and size of cholinergic neurons in rats with unilateral lesion of the nucleus basalis. 54
Lesions of the nucleus basalis magnocellularis in immature rats: short- and long-term biochemical and behavioral changes. 52
Administration of amyloid ß-peptides into the medial septum of rats decreases acetylcholine release from hippocampus "in vivo" 52
Effect of haloperidol and pimozide on acetylcholine output from the cerebral cortex in rats and guinea pigs. 50
Albumin Nanoparticles for Brain Delivery: A Comparison of Chemical versus Thermal Methods and invivo Behavior 50
Gangliosides in the repair of brain cholinergic neurons. 48
Activation of the p38MAPK pathway cascade in models of neurodegenerative diseases in the rat in vivo 47
Rivastigmine antagonises deficits in prepulse inhibition induced by selective immunolesioning of cholinergic neurons in nucleus basalis magnocellularis 46
Acetylcholine and amino acid neurotransmitters in epidural cups of freely moving rats: effect of acute and chronic treatment with antischizophrenic drugs. 46
Induction of inflammatory mediators and microglial activation in mice transgenic for human P301S tau protein 46
The release of GABA and glutamate from the cerebral cortex is an index of the activity of underlying aminoacidergic neurons. 46
Comparison between flurbiprofen and its nitric oxide-releasing derivatives HCT-1026 and NCX-2216 on Abeta(1-42)-induced brain inflammation and neuronal damage in the rat 45
Proteomic identification of proteins specifically oxidized by intracerebroventricular injection of Aß(1-42) into rat brain: implications for Alzheimer’s disease 44
The brain cholinergic system in ageing mammals. 44
Totale 8.996
Categoria #
all - tutte 26.106
article - articoli 0
book - libri 0
conference - conferenze 0
curatela - curatele 0
other - altro 0
patent - brevetti 0
selected - selezionate 0
volume - volumi 0
Totale 26.106

Totale Lug Ago Sett Ott Nov Dic Gen Feb Mar Apr Mag Giu
2018/2019829 0 0 0 0 0 0 0 0 0 164 370 295
2019/20202.386 167 198 81 191 255 302 240 323 224 134 232 39
2020/20211.708 159 126 133 153 51 205 96 162 126 274 95 128
2021/2022939 22 104 49 40 53 54 35 43 51 42 189 257
2022/20232.447 251 296 125 208 221 480 329 125 267 6 79 60
2023/2024677 47 120 154 42 52 83 29 140 7 3 0 0
Totale 10.573