MATUCCI, ROSANNA
 Distribuzione geografica
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Continente #
NA - Nord America 6.237
EU - Europa 3.926
AS - Asia 889
AF - Africa 16
Continente sconosciuto - Info sul continente non disponibili 2
SA - Sud America 2
OC - Oceania 1
Totale 11.073
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Nazione #
US - Stati Uniti d'America 6.223
RU - Federazione Russa 1.176
PL - Polonia 904
SE - Svezia 480
IE - Irlanda 450
IT - Italia 327
SG - Singapore 223
HK - Hong Kong 195
VN - Vietnam 178
UA - Ucraina 166
DE - Germania 151
CN - Cina 150
FI - Finlandia 105
GB - Regno Unito 89
IN - India 61
JO - Giordania 49
TR - Turchia 24
BE - Belgio 20
CH - Svizzera 18
CI - Costa d'Avorio 11
CA - Canada 9
NL - Olanda 8
RO - Romania 8
ES - Italia 6
FR - Francia 6
MX - Messico 4
NO - Norvegia 3
SC - Seychelles 3
AT - Austria 2
EU - Europa 2
IR - Iran 2
JP - Giappone 2
KR - Corea 2
MK - Macedonia 2
ZA - Sudafrica 2
AU - Australia 1
BR - Brasile 1
CU - Cuba 1
CZ - Repubblica Ceca 1
EE - Estonia 1
GR - Grecia 1
KZ - Kazakistan 1
LK - Sri Lanka 1
LU - Lussemburgo 1
ME - Montenegro 1
PE - Perù 1
TH - Thailandia 1
Totale 11.073
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Città #
Santa Clara 949
Warsaw 903
Fairfield 817
Chandler 468
Dublin 450
Woodbridge 401
Ashburn 393
Cambridge 326
Seattle 313
Houston 308
Jacksonville 293
Wilmington 268
Ann Arbor 215
Singapore 179
Dong Ket 175
Princeton 113
Hong Kong 110
Altamura 94
Boardman 94
Lawrence 94
Boston 90
Buffalo 62
Mumbai 58
Beijing 45
Florence 42
San Diego 38
Shanghai 36
Medford 30
Moscow 25
Falls Church 21
Izmir 21
Brussels 20
Bern 17
Milan 16
West Jordan 16
Kent 15
Los Angeles 15
Norwalk 15
Hillsboro 14
Rome 14
Andover 13
Dearborn 13
New York 12
Abidjan 11
Bari 10
Frankfurt Am Main 8
Munich 8
Guangzhou 7
Lappeenranta 7
Phoenix 7
Toronto 7
Verona 7
Barcelona 6
Helsinki 6
Laurel 6
Philadelphia 6
Washington 6
Yubileyny 6
London 5
Düsseldorf 4
Southwark 4
Tappahannock 4
Auburn Hills 3
Bremen 3
Catanzaro 3
Oslo 3
Redwood City 3
San Tan Valley 3
Amsterdam 2
Anghiari 2
Arezzo 2
Ascoli Piceno 2
Augusta 2
Cape Town 2
Chicago 2
Council Bluffs 2
Dallas 2
Gavirate 2
Giugliano in Campania 2
Groningen 2
Hackney 2
Hefei 2
Misano Adriatico 2
Montefredane 2
Monza 2
Muğla 2
Nanjing 2
Napoli 2
Ningbo 2
Norrtälje 2
Parma 2
Pontedera 2
Southend 2
Tokyo 2
Tucson 2
Târgu Mureş 2
Venezia 2
Vercelli 2
Vienna 2
Acton 1
Totale 7.817
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Nome #
3-Iodothyroacetic acid (TA1), a by-product of thyroid hormone metabolism, reduces the hypnotic effect of ethanol without interacting at GABA-A receptors. 268
Antisense knockdowns of M1 receptors induces transient anterograde amnesia in mice 261
Young human cholinergic neurons respond to physiological regulators and improve cognitive symptoms in an animal model of Alzheimer’s disease 242
3-iodothyronamine (T1AM), a novel antagonist of muscarinic receptors. 239
Pharmacological effects of 3-iodothyronamine (T1AM) in mice include facilitation of memory acquisition and retention and reduction of pain threshold 228
Synthesis and evaluation as PDE4 inhibitors of pyrimidine-2,4-dione derivatives 225
Late sodium current inhibitors to treat exercise induced obstruction in hypertrophic cardiomyopathy: an in vitro study in human myocardium. 208
1,2,4-Benzothiadiazine-1,1-dioxide Derivatives as Ionotropic Glutamate Receptor Ligands: Synthesis and Structure–Activity Relationships 175
The new low-toxic histone deacetylase inhibitor S-(2) induces apoptosis in various acute myeloid leukemia cells 172
MOLECULAR MODULATION OF MUSCARINIC ANTAGONISTS. SYNTHESIS AND AFFINITY PROFILE OF 2,2-DIPHENYL-2-ETHYLTHIO-ACETIC ACID ESTERS DESIGNED TO PROBE THE BINDING SITE CAVITY 171
1,4-dioxane, a suitable scaffold for the development of novel M₃ muscarinic receptor antagonists. 146
1,3-oxathiolane muscarinic ligands modified at the cationic head. 143
1-[3-(4-Butylpiperidin-1-yl)propyl]-1,2,3,4-tetrahydroquinolin-2-one (77-LH-28-1) as a Model for the Rational Design of a Novel Class of Brain Penetrant Ligands with High Affinity and Selectivity for Dopamine D 4 Receptor 139
Highly chiral muscarinic ligands: the discovery of (2S,2'R,3'S,5'R)-1-methyl-2-(2-methyl-1,3-oxathiolan-5-yl)pyrrolidine 3-sulfoxide methyl iodide, a potent, functionally selective, M2 partial agonist. 138
Synthesis and Cholinergic Affinity of Diastereomeric and Enantiomeric Isomers of 1-Methyl-2-(2-methyl-1,3-dioxolan-4-yl)-pyrrolidine, 1-Methyl-2-(2-methyl-1,3-oxathiolan-5-yl)pyrrolidine and of Their Iodomethylates 135
Antagonisti muscarinici a struttura 1,3-ossatiolano-2-pirrolidinica 134
SYNTHESIS, AFFINITY PROFILE AND FUNCTIONAL ACTIVITY OF MUSCARINIC ANTAGONISTS WITH A 1-METHYL-2-(2,2-ALKYLARYL-1,3-OXATHIOLAN-5-YL)PYRROLIDINE STRUCTURE 133
(1,3-Dioxolane)- and (1,3-oxathiolane)-2-pyrrolidines: molecular hybrids with potential anti-Alzheimer activity 132
Discovery of β-Adrenergic Receptors Blocker-Carbonic Anhydrase Inhibitor Hybrids for Multitargeted Antiglaucoma Therapy 131
Differential inhibitory effect of taurine on contractile responses to potassium and noradrenaline in rabbit ear artery. 128
Do ethoxy radicals reduce 3H-nitrendipine binding in rat cardiac membranes? 125
Carbachol dimers as homobivalent modulators of muscarinic receptors 125
ANTINOCICEPTIVE ACTIVITY OF A 3(2H)-PYRIDAZINONE DERIVATE IN MICE 121
Effect of taurine on calcium levels and contractility in guinea-pig ventricular strips. 120
Ticagrelor-related dyspnea: An underestimated and poorly managed event? 120
PRESYNAPTIC AUTO- AND HETERO-RECEPTORS IN THE CHOLINERGIC REGULATION OF PAIN 119
Characterization of [3H]substance P binding sites in human skin. 118
Effects of a new potent analog of tocainide on hNav1.7 sodium channels and in vivo neuropathic pain models. 118
Calcium modulatory properties of 2,6-dibutylbenzylamine (B25) in rat isolated vas deferens, cardiac and smooth muscle preparations. 116
Muscarinic antagonists with multiple stereocenters: synthesis, affinity profile and functional activity of isomeric 1-methyl-2-(2,2-alkylaryl-1,3-oxathiolan-5-yl)pyrrolidine sulfoxide derivatives 115
Properly substituted 1,4-dioxane nucleus favours the selective M3 muscarinic receptor activation. 113
The effect of taurine on excitatory receptor binding in rat hippocampal membranes 112
Inotropic effect of taurine in guinea-pig ventricular strips. 112
Muscarinic subtype affinity and functional activity profile of 1-methyl-2-(2-methyl-1,3-dioxolan-4-yl)pyrrolidine and 1-methyl-2-(2-methyl-1,3-oxathiolan-5-yl)pyrrolidine derivatives. 112
Calcium channel antagonists discovered by a multidisciplinary approach. 110
The replacement of the 2-methoxy substituent of N-((6,6-diphenyl-1,4-dioxan-2-yl)methyl)-2-(2-methoxyphenoxy)ethan-1-amine improves the selectivity for 5-HT1A receptor over α1-adrenoceptor and D2-like receptor subtypes 107
Safety aspects of iodinated contrast media related to their physicochemical properties: a pharmacoepidemiology study in two Tuscany hospitals 107
Liver function following hypovolemic hypotension in rats anaesthetized with halothane or enflurane. 107
REDUCED FLEXIBILITY ANALOGS OF ANALGESIC AND COGNITION-ENHANCING A-TROPANYL ESTERS 106
Antagonism/agonism modulation to build novel antihypertensives selectively triggering I1-imidazoline receptor activation 105
Carbon centered radicals reduce the density of L-type calcium channels in rat cardiac membranes. 105
Structure-activity relationships in 2,2-diphenyl-2-ethylthioacetic acid esters: unexpected agonistic activity in a series of muscarinic antagonists. 103
The protective effects of taurine on hypoxia (performed in the absence of glucose) and on reoxygenation (in the presence of glucose) in guinea-pig heart. 103
Muscarine-like compounds derived from a pyrolysis product of cellulose 103
Cardiac hypoxia and subsequent reoxygenation: sensitivity to L-arginine methylester 102
MOLECULAR MODULATION OF MUSCARINIC ANTAGONISTS. SYNTHESIS AND PHARMACOLOGICAL PROFILE OF 2,2-DIPHENYL-2-ETHYLTHIOACETIC AND 3,3-DIPHENYL-3-ETHYLTHIOPROPIONIC ACID DERIVATIVES CHARACTERIZED BY A DIPEPTIDE SPACER 102
Design, synthesis and preliminary pharmacological evaluation of 4-aminopiperidine derivatives as N-type calcium channel blockers active on pain and neuropathic pain 102
Synthesis and biological evaluation of chiral α-aminoanilides with central antinociceptive activity 101
[3H]-nitrendipine binding in membranes obtained from hypoxic and reoxygenated heart. 101
Does aspirin attenuate the beneficial effect of ACE inhibitors in elderly people with heart failure? 100
The conformational and property space of acetylcholine bound to muscarinic receptors: an entropy component accounts for the subtype selectivity of acetylcholine 100
L-arginine methylester reduces Ca2+/Cl(-)-dependent L-[3H]glutamate binding and Ca2+-activated neutral protease activity in rat hippocampal membranes. 100
New insights in the metabolism of Oxybutynin: evidence of N-oxidation of propargylamine moiety and rearrangement to enaminoketone 100
STEREOSELECTIVITY IN CENTRAL ANALGESIC ACTION OF TOCAINIDE AND ITS ANALOGS 99
Synthesis and biological evaluation of 2-mercapto-1,3-benzothiazole derivatives with potential antimicrobial activity 99
Protective effect of darodipine, a calcium antagonist, on rat cardiomyocytes against oxygen radical-mediated injury 99
Novel muscarinic acetylcholine receptor hybrid ligands embedding quinuclidine and 1,4-dioxane fragments 99
Understanding Oxadiazolothiazinone Biological Properties: Negative Inotropic Activity versus Cytochrome P450-Mediated Metabolism 99
Synthesis, Affinity Profile and Functional Activity of Potent Chiral Muscarinic Antagonists with a Pyrrolidinylfuran Structure 95
Positive inotropic effect of some taurine-related compounds on guinea-pig ventricular strips perfused with low calcium medium. 95
SYNTHESIS AND BIOLOGICAL ACTIVITY OF A SERIES OF ARYL TROPANYL ESTERS AND AMIDES CHEMICALLY RELATED TO 1H-INDOLE-3-CARBOXYLIC ACID ENDO 8-METHYL-8-AZABICYCLO[3.2.1]OCT-3-YL ESTER 94
Synthesis and pharmacological characterization of chiral pyrrolidinylfuran derivatives: the discovery of new functionally selective muscarinic agonists 94
Effects of leucine methylester on guinea-pig atria. 94
Effect of taurine, L-cysteic and orthanilic acids on cardiac tension. 93
On the presence of H1-receptors in various sections of guinea-pig heart: a correlation between binding and functional studies. 93
Rapid novel divergent synthesis and muscarinic agonist profile of all four optical isomers of N,N,N-trimethyl(6-methyl-1,4-dioxan-2-yl)methanaminium iodide. 92
Chiral aryloxyalkylamines: Selective 5-HT(1B/1D) activation and analgesic activity 91
Constitutive muscarinic receptors are involved in the growth and differentiation of friend erythroleukemia cells. 90
Influence of oestrogens on muscarinic receptor density and contractile response in the guinea-pig uterus. 90
Carbachol dimers with primary carbamate groups as homobivalent modulators of muscarinic receptors 90
Modulazione molecolare di antagonisti muscarinici. Sintesi e valutazione farmacologica preliminare di esteri amminoalchil piperazinici e piperidinici dell'acido 2,2-difenil-2-etiltioacetico 85
Electrophysiologic effects of lercanidipine on repolarizing potassium currents. 85
A protective effect of taurine on "hypoxic" and "reoxygenated" guinea pig heart. 84
Analoghi a ridotta flessibilità molecolare di nuovi farmaci ad azione nootropa ed analgesica 84
synthesis, chiral HPLC separation and pharmacological characterization of muscarinic furan derivatives 83
Playing with opening and closing of heterocycles: using the cusmano-ruccia reaction to develop a novel class of oxadiazolothiazinones, active as calcium channel modulators and P-glycoprotein inhibitors. 83
Cholinergic Receptor Binding Profile of Hypericum perforatum L. and its Active Constituents 81
Taurine antagonizes the alpha-adrenergic-positive inotropic effect of phenylephrine. 79
Synthesis and biological evaluation of a novel series of heterobivalent muscarinic ligands based on xanomeline and 1-[3-(4-butylpiperidin-1-yl)propyl]-1,2,3,4-tetrahydroquinolin-2-one (77-LH-28-1) 76
Novel muscarinic acetylcholine receptor hybrid ligands embedding quinuclidine and 1,4-dioxane fragments. 75
Design, synthesis and binding affinity of acetylcholine carbamoyl analogues 74
Beta1 and Beta2 adrenoceptors in human ventricular myocytes: a study of their proportion and signaling pathways. 73
Influence of lithium on the positive inotropic effect of phenylephrine and isoprenaline in guinea-pig heart. 73
Highly chiral muscarinic ligands: synthesis and affinity of diastereomeric and enantiomeric isomers of 1-methyl-2-(2-methyl-1,3-oxathiolane-5-yl)pyrrolidine 3-sulfoxides and their methyl iodides 73
Electropysiologic effects of lercanidipine on repolarizing potassium currents 72
Sintesi e valutazione farmacologica di derivati furanici e tetraidrofuranici a potenziale azione muscarinica 72
The effect of losartan on expression of beta-adrenoceptors in cardiomyocytes of diabetic and normoglycemic rats 72
Functional and binding evidence of taurine inhibition of alpha-adrenoceptor effects on guinea-pig ventricle. 72
Mode of interaction of 1,4-dioxane agonists at the M2 and M3 muscarinic receptor orthosteric sites. 71
Sintesi e affinità per i recettori colinergici degli stereoisomeri della 1-metil-2-(2-metil-1,3-diossolan-4-il)pirrolidina, della 1-metil-2-(2-metil-1,3-ossatiolan-5-il)pirrolidina e dei loro iodometilati 71
Sovrappeso indotto da farmaci 68
Molecular modulation of muscarinic antagonists. Synthesis and pharmacological profile of 2,2-diphenyl-2-ethylthioacetic acid and 3,3-diphenyl-3-ethylthiopropionic acid derivatives characterized by a dipeptide spacer 64
2-Hydroxy-1,2,4-benzothiadiazin-1,1-dioxide derivatives as new antagonists of ionotropic glutamate receptors 63
Design, Synthesis and binding affinity of carbachol dimers as bitopic ligands 61
Synthesis and pharmacological characterization of diastereomeric and enantiomeric isomers of 1-methyl-2-(2-methyl-1,3-oxathiolane-5-yl)pyrrolidine 3-sulfoxides and their methyl iodides 60
Design, synthesis and preliminary pharmacological evaluation of alkylderivatives of 4-aminopiperidine as N-type calcium channels blockers 59
The direct stimulation of gi protein by neuropeptide Y in the rat cardiac left ventricle 58
Novel Potent Muscarinic Receptor Antagonists: Investigation on the Nature of Lipophilic Substituents in the 5- And/or 6-Positions of the 1,4-Dioxane Nucleus 56
OXIDATIVE STRESS:CLINICAL IMPLICATIONS IN CARDIAC SURGERY 55
Unexpected agonistic activity in a series of muscarinic antagonists 54
Totale 10.900
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Categoria #
all - tutte 29.724
article - articoli 0
book - libri 0
conference - conferenze 0
curatela - curatele 0
other - altro 0
patent - brevetti 0
selected - selezionate 0
volume - volumi 0
Totale 29.724
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Totale Lug Ago Sett Ott Nov Dic Gen Feb Mar Apr Mag Giu
2019/20201.433 0 0 0 0 217 257 213 255 189 104 167 31
2020/20211.362 107 76 108 106 30 160 44 109 104 195 69 254
2021/2022752 28 70 65 19 32 32 39 44 30 31 180 182
2022/20231.934 187 324 95 142 144 350 268 111 209 14 60 30
2023/2024629 28 80 113 37 33 79 16 140 10 37 28 28
2024/20252.785 174 457 289 679 1.186 0 0 0 0 0 0 0
Totale 11.166