MATUCCI, ROSANNA
 Distribuzione geografica
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Continente #
NA - Nord America 7.054
EU - Europa 4.000
AS - Asia 1.333
SA - Sud America 104
OC - Oceania 49
AF - Africa 24
Continente sconosciuto - Info sul continente non disponibili 2
Totale 12.566
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Nazione #
US - Stati Uniti d'America 7.032
RU - Federazione Russa 1.183
PL - Polonia 907
SE - Svezia 480
IE - Irlanda 450
HK - Hong Kong 442
SG - Singapore 381
IT - Italia 338
VN - Vietnam 184
UA - Ucraina 167
CN - Cina 158
DE - Germania 158
FI - Finlandia 113
BR - Brasile 94
GB - Regno Unito 93
IN - India 62
AU - Australia 49
JO - Giordania 49
FR - Francia 27
TR - Turchia 25
BE - Belgio 20
CH - Svizzera 18
CA - Canada 11
CI - Costa d'Avorio 11
NL - Olanda 11
ID - Indonesia 9
RO - Romania 8
ES - Italia 6
MX - Messico 6
IQ - Iraq 5
AR - Argentina 4
PK - Pakistan 4
AT - Austria 3
EE - Estonia 3
EG - Egitto 3
NO - Norvegia 3
SC - Seychelles 3
ZA - Sudafrica 3
CR - Costa Rica 2
EU - Europa 2
IR - Iran 2
JP - Giappone 2
KR - Corea 2
KZ - Kazakistan 2
LV - Lettonia 2
MK - Macedonia 2
NG - Nigeria 2
PS - Palestinian Territory 2
PT - Portogallo 2
VE - Venezuela 2
AE - Emirati Arabi Uniti 1
BO - Bolivia 1
CL - Cile 1
CU - Cuba 1
CZ - Repubblica Ceca 1
DZ - Algeria 1
GR - Grecia 1
GT - Guatemala 1
HU - Ungheria 1
LK - Sri Lanka 1
LT - Lituania 1
LU - Lussemburgo 1
MA - Marocco 1
ME - Montenegro 1
PA - Panama 1
PE - Perù 1
PY - Paraguay 1
SA - Arabia Saudita 1
TH - Thailandia 1
Totale 12.566
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Città #
Santa Clara 1.680
Warsaw 904
Fairfield 817
Chandler 468
Dublin 450
Woodbridge 401
Ashburn 393
Hong Kong 357
Cambridge 326
Seattle 313
Houston 310
Jacksonville 293
Wilmington 268
Singapore 217
Ann Arbor 215
Dong Ket 175
Princeton 113
Altamura 94
Boardman 94
Lawrence 94
Boston 92
Buffalo 62
Mumbai 58
Melbourne 49
Beijing 47
Florence 43
San Diego 38
Shanghai 36
Medford 30
Moscow 25
Falls Church 21
Izmir 21
Los Angeles 21
Brussels 20
The Dalles 20
Milan 18
Paris 18
Bern 17
West Jordan 16
Kent 15
Norwalk 15
Helsinki 14
Hillsboro 14
Rome 14
Andover 13
Dearborn 13
New York 12
Abidjan 11
Bari 10
Jakarta 9
Frankfurt Am Main 8
Munich 8
Guangzhou 7
Lappeenranta 7
Phoenix 7
Toronto 7
Verona 7
Barcelona 6
Laurel 6
Philadelphia 6
São Paulo 6
Washington 6
Yubileyny 6
Council Bluffs 5
London 5
Campinas 4
Düsseldorf 4
Perugia 4
Southwark 4
Tappahannock 4
Amsterdam 3
Auburn Hills 3
Baghdad 3
Bremen 3
Catanzaro 3
Hanoi 3
Muğla 3
Oslo 3
Redwood City 3
Ribeirão Preto 3
San Tan Valley 3
Santa Cruz do Sul 3
Tallinn 3
Vienna 3
Almaty 2
Anghiari 2
Arezzo 2
Ascoli Piceno 2
Augusta 2
Belo Horizonte 2
Cape Town 2
Chicago 2
Dallas 2
Franca 2
Frankfurt am Main 2
Gavirate 2
Giugliano in Campania 2
Giza 2
Groningen 2
Hackney 2
Totale 8.965
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Nome #
3-Iodothyroacetic acid (TA1), a by-product of thyroid hormone metabolism, reduces the hypnotic effect of ethanol without interacting at GABA-A receptors. 292
Antisense knockdowns of M1 receptors induces transient anterograde amnesia in mice 272
3-iodothyronamine (T1AM), a novel antagonist of muscarinic receptors. 267
Young human cholinergic neurons respond to physiological regulators and improve cognitive symptoms in an animal model of Alzheimer’s disease 257
Pharmacological effects of 3-iodothyronamine (T1AM) in mice include facilitation of memory acquisition and retention and reduction of pain threshold 241
Synthesis and evaluation as PDE4 inhibitors of pyrimidine-2,4-dione derivatives 236
Late sodium current inhibitors to treat exercise induced obstruction in hypertrophic cardiomyopathy: an in vitro study in human myocardium. 229
MOLECULAR MODULATION OF MUSCARINIC ANTAGONISTS. SYNTHESIS AND AFFINITY PROFILE OF 2,2-DIPHENYL-2-ETHYLTHIO-ACETIC ACID ESTERS DESIGNED TO PROBE THE BINDING SITE CAVITY 193
The new low-toxic histone deacetylase inhibitor S-(2) induces apoptosis in various acute myeloid leukemia cells 190
1,2,4-Benzothiadiazine-1,1-dioxide Derivatives as Ionotropic Glutamate Receptor Ligands: Synthesis and Structure–Activity Relationships 189
1,4-dioxane, a suitable scaffold for the development of novel M₃ muscarinic receptor antagonists. 163
1,3-oxathiolane muscarinic ligands modified at the cationic head. 154
Highly chiral muscarinic ligands: the discovery of (2S,2'R,3'S,5'R)-1-methyl-2-(2-methyl-1,3-oxathiolan-5-yl)pyrrolidine 3-sulfoxide methyl iodide, a potent, functionally selective, M2 partial agonist. 153
Antagonisti muscarinici a struttura 1,3-ossatiolano-2-pirrolidinica 149
Discovery of β-Adrenergic Receptors Blocker-Carbonic Anhydrase Inhibitor Hybrids for Multitargeted Antiglaucoma Therapy 149
(1,3-Dioxolane)- and (1,3-oxathiolane)-2-pyrrolidines: molecular hybrids with potential anti-Alzheimer activity 149
SYNTHESIS, AFFINITY PROFILE AND FUNCTIONAL ACTIVITY OF MUSCARINIC ANTAGONISTS WITH A 1-METHYL-2-(2,2-ALKYLARYL-1,3-OXATHIOLAN-5-YL)PYRROLIDINE STRUCTURE 148
1-[3-(4-Butylpiperidin-1-yl)propyl]-1,2,3,4-tetrahydroquinolin-2-one (77-LH-28-1) as a Model for the Rational Design of a Novel Class of Brain Penetrant Ligands with High Affinity and Selectivity for Dopamine D 4 Receptor 147
Synthesis and Cholinergic Affinity of Diastereomeric and Enantiomeric Isomers of 1-Methyl-2-(2-methyl-1,3-dioxolan-4-yl)-pyrrolidine, 1-Methyl-2-(2-methyl-1,3-oxathiolan-5-yl)pyrrolidine and of Their Iodomethylates 146
Do ethoxy radicals reduce 3H-nitrendipine binding in rat cardiac membranes? 144
Differential inhibitory effect of taurine on contractile responses to potassium and noradrenaline in rabbit ear artery. 142
Carbachol dimers as homobivalent modulators of muscarinic receptors 142
Ticagrelor-related dyspnea: An underestimated and poorly managed event? 140
Effect of taurine on calcium levels and contractility in guinea-pig ventricular strips. 137
ANTINOCICEPTIVE ACTIVITY OF A 3(2H)-PYRIDAZINONE DERIVATE IN MICE 134
Effects of a new potent analog of tocainide on hNav1.7 sodium channels and in vivo neuropathic pain models. 134
Inotropic effect of taurine in guinea-pig ventricular strips. 133
Safety aspects of iodinated contrast media related to their physicochemical properties: a pharmacoepidemiology study in two Tuscany hospitals 133
Calcium modulatory properties of 2,6-dibutylbenzylamine (B25) in rat isolated vas deferens, cardiac and smooth muscle preparations. 133
Characterization of [3H]substance P binding sites in human skin. 130
The effect of taurine on excitatory receptor binding in rat hippocampal membranes 130
PRESYNAPTIC AUTO- AND HETERO-RECEPTORS IN THE CHOLINERGIC REGULATION OF PAIN 129
Properly substituted 1,4-dioxane nucleus favours the selective M3 muscarinic receptor activation. 128
Muscarinic antagonists with multiple stereocenters: synthesis, affinity profile and functional activity of isomeric 1-methyl-2-(2,2-alkylaryl-1,3-oxathiolan-5-yl)pyrrolidine sulfoxide derivatives 128
Muscarinic subtype affinity and functional activity profile of 1-methyl-2-(2-methyl-1,3-dioxolan-4-yl)pyrrolidine and 1-methyl-2-(2-methyl-1,3-oxathiolan-5-yl)pyrrolidine derivatives. 127
Carbon centered radicals reduce the density of L-type calcium channels in rat cardiac membranes. 127
The replacement of the 2-methoxy substituent of N-((6,6-diphenyl-1,4-dioxan-2-yl)methyl)-2-(2-methoxyphenoxy)ethan-1-amine improves the selectivity for 5-HT1A receptor over α1-adrenoceptor and D2-like receptor subtypes 124
MOLECULAR MODULATION OF MUSCARINIC ANTAGONISTS. SYNTHESIS AND PHARMACOLOGICAL PROFILE OF 2,2-DIPHENYL-2-ETHYLTHIOACETIC AND 3,3-DIPHENYL-3-ETHYLTHIOPROPIONIC ACID DERIVATIVES CHARACTERIZED BY A DIPEPTIDE SPACER 123
Protective effect of darodipine, a calcium antagonist, on rat cardiomyocytes against oxygen radical-mediated injury 122
Liver function following hypovolemic hypotension in rats anaesthetized with halothane or enflurane. 122
Antagonism/agonism modulation to build novel antihypertensives selectively triggering I1-imidazoline receptor activation 121
Calcium channel antagonists discovered by a multidisciplinary approach. 120
Cardiac hypoxia and subsequent reoxygenation: sensitivity to L-arginine methylester 119
The protective effects of taurine on hypoxia (performed in the absence of glucose) and on reoxygenation (in the presence of glucose) in guinea-pig heart. 118
[3H]-nitrendipine binding in membranes obtained from hypoxic and reoxygenated heart. 117
Synthesis and biological evaluation of 2-mercapto-1,3-benzothiazole derivatives with potential antimicrobial activity 116
Muscarine-like compounds derived from a pyrolysis product of cellulose 116
REDUCED FLEXIBILITY ANALOGS OF ANALGESIC AND COGNITION-ENHANCING A-TROPANYL ESTERS 115
STEREOSELECTIVITY IN CENTRAL ANALGESIC ACTION OF TOCAINIDE AND ITS ANALOGS 115
L-arginine methylester reduces Ca2+/Cl(-)-dependent L-[3H]glutamate binding and Ca2+-activated neutral protease activity in rat hippocampal membranes. 115
Carbachol dimers with primary carbamate groups as homobivalent modulators of muscarinic receptors 115
Structure-activity relationships in 2,2-diphenyl-2-ethylthioacetic acid esters: unexpected agonistic activity in a series of muscarinic antagonists. 113
Design, synthesis and preliminary pharmacological evaluation of 4-aminopiperidine derivatives as N-type calcium channel blockers active on pain and neuropathic pain 112
Positive inotropic effect of some taurine-related compounds on guinea-pig ventricular strips perfused with low calcium medium. 112
Synthesis, Affinity Profile and Functional Activity of Potent Chiral Muscarinic Antagonists with a Pyrrolidinylfuran Structure 111
New insights in the metabolism of Oxybutynin: evidence of N-oxidation of propargylamine moiety and rearrangement to enaminoketone 110
SYNTHESIS AND BIOLOGICAL ACTIVITY OF A SERIES OF ARYL TROPANYL ESTERS AND AMIDES CHEMICALLY RELATED TO 1H-INDOLE-3-CARBOXYLIC ACID ENDO 8-METHYL-8-AZABICYCLO[3.2.1]OCT-3-YL ESTER 108
Synthesis and pharmacological characterization of chiral pyrrolidinylfuran derivatives: the discovery of new functionally selective muscarinic agonists 108
Effects of leucine methylester on guinea-pig atria. 108
Effect of taurine, L-cysteic and orthanilic acids on cardiac tension. 108
Novel muscarinic acetylcholine receptor hybrid ligands embedding quinuclidine and 1,4-dioxane fragments 108
Synthesis and biological evaluation of chiral α-aminoanilides with central antinociceptive activity 106
The conformational and property space of acetylcholine bound to muscarinic receptors: an entropy component accounts for the subtype selectivity of acetylcholine 106
Does aspirin attenuate the beneficial effect of ACE inhibitors in elderly people with heart failure? 105
Modulazione molecolare di antagonisti muscarinici. Sintesi e valutazione farmacologica preliminare di esteri amminoalchil piperazinici e piperidinici dell'acido 2,2-difenil-2-etiltioacetico 104
Understanding Oxadiazolothiazinone Biological Properties: Negative Inotropic Activity versus Cytochrome P450-Mediated Metabolism 104
Electrophysiologic effects of lercanidipine on repolarizing potassium currents. 103
On the presence of H1-receptors in various sections of guinea-pig heart: a correlation between binding and functional studies. 102
synthesis, chiral HPLC separation and pharmacological characterization of muscarinic furan derivatives 100
A protective effect of taurine on "hypoxic" and "reoxygenated" guinea pig heart. 100
Constitutive muscarinic receptors are involved in the growth and differentiation of friend erythroleukemia cells. 99
Rapid novel divergent synthesis and muscarinic agonist profile of all four optical isomers of N,N,N-trimethyl(6-methyl-1,4-dioxan-2-yl)methanaminium iodide. 98
Influence of oestrogens on muscarinic receptor density and contractile response in the guinea-pig uterus. 97
Chiral aryloxyalkylamines: Selective 5-HT(1B/1D) activation and analgesic activity 96
Taurine antagonizes the alpha-adrenergic-positive inotropic effect of phenylephrine. 95
Beta1 and Beta2 adrenoceptors in human ventricular myocytes: a study of their proportion and signaling pathways. 94
Analoghi a ridotta flessibilità molecolare di nuovi farmaci ad azione nootropa ed analgesica 94
Highly chiral muscarinic ligands: synthesis and affinity of diastereomeric and enantiomeric isomers of 1-methyl-2-(2-methyl-1,3-oxathiolane-5-yl)pyrrolidine 3-sulfoxides and their methyl iodides 94
Playing with opening and closing of heterocycles: using the cusmano-ruccia reaction to develop a novel class of oxadiazolothiazinones, active as calcium channel modulators and P-glycoprotein inhibitors. 93
Sintesi e valutazione farmacologica di derivati furanici e tetraidrofuranici a potenziale azione muscarinica 91
Cholinergic Receptor Binding Profile of Hypericum perforatum L. and its Active Constituents 90
Electropysiologic effects of lercanidipine on repolarizing potassium currents 89
Functional and binding evidence of taurine inhibition of alpha-adrenoceptor effects on guinea-pig ventricle. 89
Molecular modulation of muscarinic antagonists. Synthesis and pharmacological profile of 2,2-diphenyl-2-ethylthioacetic acid and 3,3-diphenyl-3-ethylthiopropionic acid derivatives characterized by a dipeptide spacer 87
The effect of losartan on expression of beta-adrenoceptors in cardiomyocytes of diabetic and normoglycemic rats 86
Sovrappeso indotto da farmaci 86
Sintesi e affinità per i recettori colinergici degli stereoisomeri della 1-metil-2-(2-metil-1,3-diossolan-4-il)pirrolidina, della 1-metil-2-(2-metil-1,3-ossatiolan-5-il)pirrolidina e dei loro iodometilati 85
Influence of lithium on the positive inotropic effect of phenylephrine and isoprenaline in guinea-pig heart. 83
Design, Synthesis and binding affinity of carbachol dimers as bitopic ligands 83
Synthesis and biological evaluation of a novel series of heterobivalent muscarinic ligands based on xanomeline and 1-[3-(4-butylpiperidin-1-yl)propyl]-1,2,3,4-tetrahydroquinolin-2-one (77-LH-28-1) 81
Novel muscarinic acetylcholine receptor hybrid ligands embedding quinuclidine and 1,4-dioxane fragments. 80
Synthesis and pharmacological characterization of diastereomeric and enantiomeric isomers of 1-methyl-2-(2-methyl-1,3-oxathiolane-5-yl)pyrrolidine 3-sulfoxides and their methyl iodides 80
Design, synthesis and binding affinity of acetylcholine carbamoyl analogues 80
Mode of interaction of 1,4-dioxane agonists at the M2 and M3 muscarinic receptor orthosteric sites. 79
The direct stimulation of gi protein by neuropeptide Y in the rat cardiac left ventricle 77
2-Hydroxy-1,2,4-benzothiadiazin-1,1-dioxide derivatives as new antagonists of ionotropic glutamate receptors 74
New endogenous triggers of atrial fibrillation 69
Design, synthesis and preliminary pharmacological evaluation of alkylderivatives of 4-aminopiperidine as N-type calcium channels blockers 69
Unexpected agonistic activity in a series of muscarinic antagonists 66
Novel Potent Muscarinic Receptor Antagonists: Investigation on the Nature of Lipophilic Substituents in the 5- And/or 6-Positions of the 1,4-Dioxane Nucleus 64
Totale 12.349
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Categoria #
all - tutte 34.415
article - articoli 0
book - libri 0
conference - conferenze 0
curatela - curatele 0
other - altro 0
patent - brevetti 0
selected - selezionate 0
volume - volumi 0
Totale 34.415
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Totale Lug Ago Sett Ott Nov Dic Gen Feb Mar Apr Mag Giu
2019/2020198 0 0 0 0 0 0 0 0 0 0 167 31
2020/20211.362 107 76 108 106 30 160 44 109 104 195 69 254
2021/2022752 28 70 65 19 32 32 39 44 30 31 180 182
2022/20231.934 187 324 95 142 144 350 268 111 209 14 60 30
2023/2024629 28 80 113 37 33 79 16 140 10 37 28 28
2024/20254.278 174 457 289 679 1.409 645 33 308 175 90 19 0
Totale 12.659