CECCHI, CRISTINA
 Distribuzione geografica
Continente #
EU - Europa 8.154
NA - Nord America 7.816
AS - Asia 1.283
OC - Oceania 79
AF - Africa 34
SA - Sud America 5
Continente sconosciuto - Info sul continente non disponibili 2
Totale 17.373
Nazione #
US - Stati Uniti d'America 7.779
PL - Polonia 4.209
RU - Federazione Russa 1.701
IT - Italia 576
IE - Irlanda 508
SE - Svezia 502
SG - Singapore 313
HK - Hong Kong 300
CN - Cina 251
DE - Germania 159
FI - Finlandia 142
UA - Ucraina 134
IN - India 133
GB - Regno Unito 82
VN - Vietnam 82
AU - Australia 72
ID - Indonesia 61
JO - Giordania 57
CH - Svizzera 43
CA - Canada 34
TR - Turchia 29
KR - Corea 28
CI - Costa d'Avorio 22
FR - Francia 21
NL - Olanda 20
ES - Italia 18
BE - Belgio 15
IR - Iran 11
RO - Romania 9
NZ - Nuova Zelanda 7
SC - Seychelles 7
JP - Giappone 5
BD - Bangladesh 3
BR - Brasile 3
MU - Mauritius 3
TW - Taiwan 3
AT - Austria 2
CZ - Repubblica Ceca 2
EG - Egitto 2
EU - Europa 2
IL - Israele 2
LT - Lituania 2
LU - Lussemburgo 2
PK - Pakistan 2
AE - Emirati Arabi Uniti 1
AZ - Azerbaigian 1
BG - Bulgaria 1
CO - Colombia 1
DK - Danimarca 1
EC - Ecuador 1
EE - Estonia 1
GR - Grecia 1
GT - Guatemala 1
JM - Giamaica 1
LV - Lettonia 1
MX - Messico 1
NO - Norvegia 1
PH - Filippine 1
PT - Portogallo 1
Totale 17.373
Città #
Warsaw 4.208
Santa Clara 2.248
Fairfield 761
Chandler 629
Dublin 507
Ashburn 420
Woodbridge 358
Seattle 311
Cambridge 310
Houston 295
Wilmington 269
Singapore 259
Hong Kong 205
Jacksonville 205
Altamura 170
Lawrence 145
Florence 140
Ann Arbor 134
Princeton 127
Boston 99
Boardman 95
Beijing 94
Mumbai 73
Dong Ket 72
Melbourne 70
Dearborn 63
Jakarta 60
Bremen 58
Shanghai 51
Moscow 48
Medford 45
San Diego 44
Pune 43
Buffalo 41
Bern 39
Helsinki 30
Phoenix 27
Kent 26
Milan 26
West Jordan 26
Izmir 23
Abidjan 22
Lappeenranta 21
Los Angeles 20
New York 20
Norwalk 20
Washington 17
Barcelona 16
Hillsboro 13
Falls Church 12
Seoul 12
Yubileyny 11
Auburn Hills 10
Brussels 10
London 10
Oakland 10
Rohtak 10
Seongnam 9
Toronto 9
Montreal 8
Redwood City 8
Verona 8
Andover 7
Hefei 7
Nanjing 7
Rome 7
Amsterdam 6
Guangzhou 6
Ottawa 6
Bucharest 5
Kunming 5
Peterborough 5
Castelliri 4
Central 4
Grenoble 4
Liège 4
Naples 4
Poggio a Caiano 4
Redmond 4
Salerno 4
Sant'oreste 4
Serra 4
Swampscott 4
Tappahannock 4
Cagliari 3
Dallas 3
Detroit 3
Hamilton 3
Hwaseong-si 3
Livorno 3
Modena 3
Newark 3
Orenburg 3
Perugia 3
Pisa 3
Romola 3
San Jose 3
San Mateo 3
Santa Maria A Monte 3
Taipei 3
Totale 13.287
Nome #
A causative link between the structure of aberrant protein oligomers and their toxicity 284
SIRT1 modulates MAPK pathways in ischemic-reperfused cardiomyocytes 268
Seladin-1/dhcr24 protects neuroblastoma cells against aβ toxicity by increasing membrane cholesterol content 267
TDP-43 inclusion bodies formed in bacteria are structurally amorphous, non-amyloid and inherently toxic to neuroblastoma cells 262
Destabilisation, aggregation, toxicity and cytosolic mislocalisation of nucleophosmin regions associated with acute myeloid leukemia 259
Patterns of cell death triggered in two different cell lines by HypF-N prefibrillar aggregates. 258
Increased susceptibility to amyloid toxicity in familial Alzheimer's fibroblasts 256
Quantification of the Relative Contributions of Loss-of function and Gain-of-function Mechanisms in TAR DNA-binding Protein 43 (TDP-43) Proteinopathies 254
SIRT1 regulates MAPK pathways in vitiligo skin: insight into the molecular pathways of cell survival 253
Binding affinity of amyloid oligomers to cellular membranes is a generic indicator of cellular dysfunction in protein misfolding diseases 253
A natural product inhibits the initiation of α-synuclein aggregation and suppresses its toxicity 249
Soluble Oligomers Require a Ganglioside to Trigger Neuronal Calcium Overload 249
Protective effect of the PARP-1 inhibitor PJ34 in hypoxic-reoxygenated cardiomyoblasts 248
TDP-43 inclusion bodies formed in bacteria are structurally amorphous, non-amyloid and inherently toxic to neuroblastoma cells 245
Effect of molecular chaperones on aberrant protein oligomers in vitro: super- versus sub-stoichiometric chaperone concentrations 245
TDP-43 inclusion bodies formed in bacteria are structurally amorphous, non-amyloid and inherently toxic to neuroblastoma cells 243
Interaction of toxic and non-toxic HypF-N oligomers with lipid bilayers investigated at high resolution with atomic force microscopy 242
Lipid Rafts Mediate Amyloid-induced Calcium Dyshomeostasis and Oxidative Stress in Alzheimer's Disease. 241
Nucleophosmin contains amyloidogenic regions that are able to form toxic aggregates under physiological conditions 232
Biochemical changes and their relationship with morphological and functional finding in pig heart subjected to lasting volume-overload: a possible role of Acylphosphatase in the regulation of sarcoplasmic reticulum calcium pump. 231
Single molecule experiments emphasize GM1 as a key player of the different cytotoxicity of structurally distinct Aβ1-42 oligomers 230
Toxic HypF-N oligomers selectively bind the plasma membrane to impair cell adhesion capability 228
Poly(ADP-ribose) polymerase activation and cell injury in the course of rat heart heterotopic transplantation. 226
Curcumin protects cardiac cells against ischemia-reperfusion injury: effects on oxidative stress, NF-kappaB, and JNK pathways 222
Membrane cholesterol enrichment prevents Abeta-induced oxidative stress in Alzheimer's fibroblasts. 221
Glutathione intake promotes longevity through the activation of SIR-2.1 and DAF-16 (FoxO) pathway in C. elegans 209
Structural basis of membrane disruption and cellular toxicity by α-synuclein oligomers 201
α-Synuclein oligomers and fibrils: partners in crime in synucleinopathies 196
The acute myeloid leukemia-associated nucleophosmin 1 gene mutations dictate amyloidogenicity of the C-terminal domain 196
Single particle tracking to study the binding of protein misfolded oligomer to membrane ganglioside GM1 193
Partial Failure of Proteostasis Systems Counteracting TDP-43 Aggregates in Neurodegenerative Diseases 190
Molecular links between aberrant protein oligomers and neurodegeneration in Alzheimer’s disease 189
Capturing Aβ42 aggregation in the cell 185
The toxicity of misfolded protein oligomers is independent of their secondary structure 182
Multistep Inhibition of α‑Synuclein Aggregation and Toxicity in Vitro and in Vivo by Trodusquemine 175
Trodusquemine enhances Aβ42 aggregation but suppresses its toxicity by displacing oligomers from cell membranes 167
Acylphosphatase levels in Alzheimer's disease cultured skin fibroblasts 164
Lipid rafts are primary mediators of amyloid oxidative attack on plasma membrane 164
Identification of Novel 1,3,5-Triphenylbenzene Derivative Compounds as Inhibitors of Hen Lysozyme Amyloid Fibril Formation 163
S-linolenoyl glutathione intake extends life-span and stress resistance via Sir-2.1 upregulation in Caenorhabditis elegans 162
Beneficial Effects of Poly (ADP-ribose) Polymerase Inhibition Against the Reperfusion Injury in Heart Transplantation 149
Nanoscopic insights into the surface conformation of neurotoxic amyloid b oligomers 144
A PEPTIDE FRACTION FROM FACTOR VIII REDUCES PKC ACTIVITY IN CULTURED ENDOTHELIAL CELLS 142
Differentiation increases the resistance of neuronal cells to amyloid toxicity 142
ALTERATION OF ACYLPHOSPHATASE LEVELS IN FAMILIAL ALZHEIMER'S DISEASE FIBROBLASTS WITH PRESENILIN GENE MUTATIONS 141
Targeting pathological amyloid aggregates with conformation-sensitive antibodies 141
Generation of reactive oxygen species by beta amyloid fibrils and oligomers involves different intra/extracellular pathways. 139
Protective Properties of Novel S-Acyl-Glutathione Thioesters Against Ultraviolet-induced Oxidative Stress 138
Molecular mechanisms used by chaperones to reduce the toxicity of aberrant protein oligomers 138
Probing the origin of the toxicity of oligomeric aggregates of α-synuclein with antibodies 138
Over-expression of amyloid precursor protein in HEK cells alters P53 conformational state and protects against doxorubicin. 137
Acylphosphatase overexpression triggers SH-SY5Y differentiation towards neuronal phenotype. 137
ALTERATION OF INTRACELLULAR FREE CALCIUM AND ACYLPHOSPHATASE LEVELS IN DIFFERENTIATING SH-SY5Y NEUROBLASTOMA CELLS 134
ALTERATION OF FREE CALCIUM LEVELS AND ACYLPHOSPHATASE MUSCULAR ISOENZYME IN CULTURED DYSTROPHIC SKIN FIBROBLASTS 133
A Complex Equilibrium among Partially Unfolded Conformations in Monomeric Transthyretin 131
A comparison of the biochemical modifications caused by toxic and non-toxic protein oligomers in cells 129
Glycosaminoglycans (GAGs) Suppress the Toxicity of HypF-N Prefibrillar Aggregates 129
DROSOPHILA MELANOGASTER ACYLPHOSPHATASE: A COMMON ANCESTOR FOR ACYLPHOSPHATASE ISOENZYMES OF VERTEBRATE SPECIES 127
CEREBRAL SOLUBLE UBIQUITIN IS INCREASED IN PATIENTS WITH ALZHEIMER'S DISEASE 127
Neuronal differentiation of human mesenchymal stromal cells increases their resistance to Aβ42 aggregate toxicity. 126
Transthyretin suppresses the toxicity of oligomers formed by misfolded proteins in vitro 126
Lack of SOD1 gene mutations and activity alterations in two Italian families with amyotrophic lateral sclerosis 125
Extracellular chaperones prevent Aβ42-induced toxicity in rat brains 124
Oxidative stress and reduced antioxidant defenses in peripheral cells from familial Alzheimer's patients. 123
A protective role for lipid raft cholesterol againsy amyloid-induced membrane damage in human neuroblastoma cells 123
Membrane lipid composition and its physicochemical properties define cell vulnerability to aberrant protein oligomers 123
Replicating neuroblastoma cells in different cell cycle phases display different vulnerability to amyloid toxicity 122
Early changes induced in the left ventricle by pressure overload. An experimental study on swine heart. 122
Novel S-acyl glutathione derivatives prevent amyloid oxidative stress and cholinergic dysfunction in Alzheimer disease models. Free Radic Biol Med. 122
Trodusquemine displaces protein misfolded oligomers from cell membranes and abrogates their cytotoxicity through a generic mechanism 122
Glutathione level is altered in lymphoblasts from patients with familial Alzheimer's disease 118
Un nuovo metodo per il dosaggio reflettometrico della emoglobina totale 118
Plasma Membrane Injury Depends on Bilayer Lipid Composition in Alzheimer’s Disease 118
Protective effect of new S-acylglutathione derivatives against amyloid induced oxidative stress 118
CRYSTALLISATION AND PRELIMINARY X-RAY ANALYSIS OF THE 'COMMON TYPE' ACYLPHOSPHATASE 117
Light-responsive nanocomposite sponges for on demand chemical release with high spatial and dosage control 116
The amyloid-cell membrane system. The interplay between the biophysical features of oligomers/fibrils and cell membrane defines amyloid toxicity 112
Quantitative assessment of the degradation of aggregated TDP-43 mediated by the ubiquitin proteasome system and macroautophagy 111
Soluble Prion peptide 107–120 protects neuroblastoma SH-SY5Y cells against oligomers associated with Alzheimer’s disease 110
Biological membranes as protein aggregation matrices and targets of amyloid toxicity 110
Differing molecular mechanisms appear to underlie early toxicity of pre-fibrillar HypF-N aggregates to different cell types 108
Insights into the molecular basis of the differing susceptibility of varying cell types to the toxicity of amyloid aggregates 106
Glutathione levels in lymphoblasts from patients with familial Alzheimer's disease linked to presenilin genes 104
Glutathione levels in Alzheimer's disease lymphoblasts 100
Squalamine and its derivatives modulate the aggregation of amyloid-β and α-synuclein and suppress the toxicity of their oligomers 97
Interaction between acylphosphatase and SERCA in SH-SY5Y cells 95
Amyloid cytotoxicity depends on membrane lipid composition in Alzheimer's disease 93
The release of toxic oligomers from α-synuclein fibrils induces dysfunction in neuronal cells 93
Toxicity of Protein Oligomers Is Rationalized by a Function Combining Size and Surface Hydrophobicity 93
Presenilin Alzheimer's disease lymphoblasts show lowere glutathione 92
Setting up and statistical evaluation of a new haemoglobin assay 91
Alzheimer’s disease lymphoblasts: evidence for oxidative stress 88
Chaperones suppress protein oligomer toxicity: Insight into the molecular mechanism of action 88
Aβ oligomers dysregulate calcium homeostasis by mechanosensitive activation of AMPA and NMDA receptors. 87
Familial Alzheimer's disease fibroblasts with presenilin gene mutations: Alteration of acylphosphatase levels 84
Investigating partially unfolded conformations populated by monomeric human transthyretin 84
EXPRESSION OF HUMAN ACYLPHOSPHATASE IN ESCHERICHIA COLI AFFECTS INTRACELLULAR CALCIUM LEVELS 83
PJ34 exerts beneficial effects on cell injury induced by hypoxia and reoxygenation in cardiomyoblasts 80
Chaperones suppress the toxicity of aberrant protein aggregates. Molecular insight into the mechanism of action 78
Alteration of free calcium levels in SY5Y cells by acylphosphatase overexpression 77
Totale 15.825
Categoria #
all - tutte 43.029
article - articoli 0
book - libri 0
conference - conferenze 0
curatela - curatele 0
other - altro 0
patent - brevetti 0
selected - selezionate 0
volume - volumi 0
Totale 43.029


Totale Lug Ago Sett Ott Nov Dic Gen Feb Mar Apr Mag Giu
2019/20201.354 0 0 0 0 0 0 282 357 239 181 252 43
2020/20211.894 148 204 76 238 116 221 99 144 157 268 78 145
2021/2022842 50 99 69 23 23 32 35 56 45 45 138 227
2022/20232.614 193 481 150 263 189 432 325 132 259 45 77 68
2023/20241.044 47 112 130 48 65 186 42 219 13 72 59 51
2024/20255.017 174 652 397 982 1.977 830 5 0 0 0 0 0
Totale 17.530