CECCHI, CRISTINA
 Distribuzione geografica
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Continente #
NA - Nord America 10.825
EU - Europa 10.330
AS - Asia 4.613
SA - Sud America 609
Continente sconosciuto - Info sul continente non disponibili 181
AF - Africa 119
OC - Oceania 87
Totale 26.764
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Nazione #
US - Stati Uniti d'America 10.630
PL - Polonia 4.224
RU - Federazione Russa 2.284
IT - Italia 1.455
SG - Singapore 1.301
CN - Cina 1.158
HK - Hong Kong 645
SE - Svezia 530
IE - Irlanda 514
VN - Vietnam 504
BR - Brasile 477
KR - Corea 372
DE - Germania 300
FI - Finlandia 241
FR - Francia 209
IN - India 198
UA - Ucraina 148
GB - Regno Unito 144
CA - Canada 122
ID - Indonesia 83
AU - Australia 74
CH - Svizzera 73
NL - Olanda 73
JO - Giordania 63
JP - Giappone 46
AR - Argentina 43
BD - Bangladesh 43
TR - Turchia 40
MX - Messico 35
ES - Italia 34
CI - Costa d'Avorio 22
NG - Nigeria 22
IQ - Iraq 21
EC - Ecuador 20
CO - Colombia 18
ZA - Sudafrica 18
BE - Belgio 16
AE - Emirati Arabi Uniti 14
RO - Romania 14
UZ - Uzbekistan 14
VE - Venezuela 14
NZ - Nuova Zelanda 13
PK - Pakistan 13
PY - Paraguay 13
IR - Iran 12
CL - Cile 11
MA - Marocco 11
SA - Arabia Saudita 11
JM - Giamaica 10
MY - Malesia 10
PH - Filippine 9
SC - Seychelles 9
SK - Slovacchia (Repubblica Slovacca) 9
AZ - Azerbaigian 8
EG - Egitto 8
IL - Israele 8
AT - Austria 7
CR - Costa Rica 7
LT - Lituania 7
AL - Albania 6
BJ - Benin 6
KE - Kenya 6
PE - Perù 6
TT - Trinidad e Tobago 6
TW - Taiwan 6
CZ - Repubblica Ceca 5
DZ - Algeria 5
PT - Portogallo 5
ET - Etiopia 4
GE - Georgia 4
HN - Honduras 4
HU - Ungheria 4
KG - Kirghizistan 4
OM - Oman 4
BG - Bulgaria 3
BH - Bahrain 3
BO - Bolivia 3
DK - Danimarca 3
GR - Grecia 3
LU - Lussemburgo 3
MU - Mauritius 3
NP - Nepal 3
PR - Porto Rico 3
UY - Uruguay 3
BA - Bosnia-Erzegovina 2
EE - Estonia 2
EU - Europa 2
GA - Gabon 2
GT - Guatemala 2
IS - Islanda 2
KZ - Kazakistan 2
LB - Libano 2
LV - Lettonia 2
MM - Myanmar 2
NO - Norvegia 2
PA - Panama 2
RS - Serbia 2
SI - Slovenia 2
SY - Repubblica araba siriana 2
TH - Thailandia 2
Totale 26.569
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Città #
Warsaw 4.220
Santa Clara 2.301
Ashburn 1.359
Singapore 940
Fairfield 762
Chandler 630
Hong Kong 545
Dublin 512
San Jose 365
Woodbridge 359
Seoul 356
Seattle 313
Cambridge 312
Houston 305
Council Bluffs 293
Milan 281
Wilmington 273
Beijing 248
Hefei 242
Jacksonville 207
Florence 191
Altamura 170
Lawrence 146
The Dalles 139
Los Angeles 138
Ann Arbor 134
Ho Chi Minh City 132
Princeton 127
Rome 115
Lauterbourg 114
Boston 112
Buffalo 103
Boardman 101
Munich 100
Hanoi 97
Mumbai 80
Helsinki 78
Moscow 76
Dallas 73
Dong Ket 72
Melbourne 71
New York 69
Shanghai 66
Jakarta 65
Dearborn 63
Bremen 58
San Diego 47
Medford 45
Pune 45
Paris 44
Kent 43
Turku 43
Bern 39
São Paulo 37
Phoenix 36
Naples 34
Tokyo 30
Lappeenranta 29
Orem 28
Bologna 26
Montreal 26
West Jordan 26
Clifton 25
Columbus 23
Izmir 23
Toronto 23
Abidjan 22
Abuja 22
Guangzhou 22
Redondo Beach 22
Norwalk 21
Turin 21
Chennai 20
London 20
Atlanta 19
Barcelona 19
Chicago 18
Haiphong 18
Washington 18
Frankfurt am Main 17
Brooklyn 16
Miano 16
Verona 16
Denver 15
Figino 15
Bari 14
Da Nang 14
Stockholm 14
Bengaluru 13
Falls Church 13
Hillsboro 13
Tashkent 13
Basel 12
Mexico City 12
Milwaukee 12
Palermo 12
Venice 12
Brussels 11
Groningen 11
Rio de Janeiro 11
Totale 18.729
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Nome #
A causative link between the structure of aberrant protein oligomers and their toxicity 485
Biochemical changes and their relationship with morphological and functional finding in pig heart subjected to lasting volume-overload: a possible role of Acylphosphatase in the regulation of sarcoplasmic reticulum calcium pump. 338
SIRT1 modulates MAPK pathways in ischemic-reperfused cardiomyocytes 338
Seladin-1/dhcr24 protects neuroblastoma cells against aβ toxicity by increasing membrane cholesterol content 338
Protective effect of the PARP-1 inhibitor PJ34 in hypoxic-reoxygenated cardiomyoblasts 332
TDP-43 inclusion bodies formed in bacteria are structurally amorphous, non-amyloid and inherently toxic to neuroblastoma cells 331
Structural basis of membrane disruption and cellular toxicity by α-synuclein oligomers 328
A natural product inhibits the initiation of α-synuclein aggregation and suppresses its toxicity 327
Binding affinity of amyloid oligomers to cellular membranes is a generic indicator of cellular dysfunction in protein misfolding diseases 327
SIRT1 regulates MAPK pathways in vitiligo skin: insight into the molecular pathways of cell survival 323
Increased susceptibility to amyloid toxicity in familial Alzheimer's fibroblasts 322
Lipid Rafts Mediate Amyloid-induced Calcium Dyshomeostasis and Oxidative Stress in Alzheimer's Disease. 316
Quantification of the Relative Contributions of Loss-of function and Gain-of-function Mechanisms in TAR DNA-binding Protein 43 (TDP-43) Proteinopathies 315
TDP-43 inclusion bodies formed in bacteria are structurally amorphous, non-amyloid and inherently toxic to neuroblastoma cells 315
Membrane cholesterol enrichment prevents Abeta-induced oxidative stress in Alzheimer's fibroblasts. 314
Effect of molecular chaperones on aberrant protein oligomers in vitro: super- versus sub-stoichiometric chaperone concentrations 314
Soluble Oligomers Require a Ganglioside to Trigger Neuronal Calcium Overload 313
Destabilisation, aggregation, toxicity and cytosolic mislocalisation of nucleophosmin regions associated with acute myeloid leukemia 313
TDP-43 inclusion bodies formed in bacteria are structurally amorphous, non-amyloid and inherently toxic to neuroblastoma cells 307
Patterns of cell death triggered in two different cell lines by HypF-N prefibrillar aggregates. 302
Single molecule experiments emphasize GM1 as a key player of the different cytotoxicity of structurally distinct Aβ1-42 oligomers 300
Interaction of toxic and non-toxic HypF-N oligomers with lipid bilayers investigated at high resolution with atomic force microscopy 298
Curcumin protects cardiac cells against ischemia-reperfusion injury: effects on oxidative stress, NF-kappaB, and JNK pathways 298
Toxic HypF-N oligomers selectively bind the plasma membrane to impair cell adhesion capability 282
Glutathione intake promotes longevity through the activation of SIR-2.1 and DAF-16 (FoxO) pathway in C. elegans 273
Nucleophosmin contains amyloidogenic regions that are able to form toxic aggregates under physiological conditions 272
S-linolenoyl glutathione intake extends life-span and stress resistance via Sir-2.1 upregulation in Caenorhabditis elegans 265
Acylphosphatase levels in Alzheimer's disease cultured skin fibroblasts 264
Poly(ADP-ribose) polymerase activation and cell injury in the course of rat heart heterotopic transplantation. 262
α-Synuclein oligomers and fibrils: partners in crime in synucleinopathies 261
A PEPTIDE FRACTION FROM FACTOR VIII REDUCES PKC ACTIVITY IN CULTURED ENDOTHELIAL CELLS 259
Molecular links between aberrant protein oligomers and neurodegeneration in Alzheimer’s disease 258
The acute myeloid leukemia-associated nucleophosmin 1 gene mutations dictate amyloidogenicity of the C-terminal domain 253
Multistep Inhibition of α‑Synuclein Aggregation and Toxicity in Vitro and in Vivo by Trodusquemine 253
Single particle tracking to study the binding of protein misfolded oligomer to membrane ganglioside GM1 251
Partial Failure of Proteostasis Systems Counteracting TDP-43 Aggregates in Neurodegenerative Diseases 247
The toxicity of misfolded protein oligomers is independent of their secondary structure 246
ALTERATION OF FREE CALCIUM LEVELS AND ACYLPHOSPHATASE MUSCULAR ISOENZYME IN CULTURED DYSTROPHIC SKIN FIBROBLASTS 245
Acylphosphatase overexpression triggers SH-SY5Y differentiation towards neuronal phenotype. 236
Beneficial Effects of Poly (ADP-ribose) Polymerase Inhibition Against the Reperfusion Injury in Heart Transplantation 234
Capturing Aβ42 aggregation in the cell 230
Lipid rafts are primary mediators of amyloid oxidative attack on plasma membrane 227
ALTERATION OF ACYLPHOSPHATASE LEVELS IN FAMILIAL ALZHEIMER'S DISEASE FIBROBLASTS WITH PRESENILIN GENE MUTATIONS 225
Nanoscopic insights into the surface conformation of neurotoxic amyloid b oligomers 222
Identification of Novel 1,3,5-Triphenylbenzene Derivative Compounds as Inhibitors of Hen Lysozyme Amyloid Fibril Formation 220
Trodusquemine enhances Aβ42 aggregation but suppresses its toxicity by displacing oligomers from cell membranes 218
Amyloid fibrils act as a reservoir of soluble oligomers, the main culprits in protein deposition diseases 209
ALTERATION OF INTRACELLULAR FREE CALCIUM AND ACYLPHOSPHATASE LEVELS IN DIFFERENTIATING SH-SY5Y NEUROBLASTOMA CELLS 209
A protective role for lipid raft cholesterol againsy amyloid-induced membrane damage in human neuroblastoma cells 207
Protective Properties of Novel S-Acyl-Glutathione Thioesters Against Ultraviolet-induced Oxidative Stress 206
Over-expression of amyloid precursor protein in HEK cells alters P53 conformational state and protects against doxorubicin. 203
Biophysical characterization of full-length TAR DNA-binding protein (TDP-43) phase separation. 202
Sphingosine 1-phosphate attenuates neuronal dysfunction induced by amyloid-β oligomers through endocytic internalization of NMDA receptors 202
Differentiation increases the resistance of neuronal cells to amyloid toxicity 202
A Complex Equilibrium among Partially Unfolded Conformations in Monomeric Transthyretin 202
A comparison of the biochemical modifications caused by toxic and non-toxic protein oligomers in cells 197
Molecular mechanisms used by chaperones to reduce the toxicity of aberrant protein oligomers 194
A quantitative biology approach correlates neuronal toxicity with the largest inclusions of TDP-43 192
An in situ and in vitro investigation of cytoplasmic TDP-43 inclusions reveals the absence of a clear amyloid signature 192
Neuronal differentiation of human mesenchymal stromal cells increases their resistance to Aβ42 aggregate toxicity. 192
Generation of reactive oxygen species by beta amyloid fibrils and oligomers involves different intra/extracellular pathways. 191
Un nuovo metodo per il dosaggio reflettometrico della emoglobina totale 190
APP and Bace1: Differential effect of cholesterol enrichment on processing and plasma membrane mobility 188
Novel S-acyl glutathione derivatives prevent amyloid oxidative stress and cholinergic dysfunction in Alzheimer disease models. Free Radic Biol Med. 188
Targeting pathological amyloid aggregates with conformation-sensitive antibodies 187
Glycosaminoglycans (GAGs) Suppress the Toxicity of HypF-N Prefibrillar Aggregates 186
DROSOPHILA MELANOGASTER ACYLPHOSPHATASE: A COMMON ANCESTOR FOR ACYLPHOSPHATASE ISOENZYMES OF VERTEBRATE SPECIES 185
Insights into the molecular basis of the differing susceptibility of varying cell types to the toxicity of amyloid aggregates 185
CEREBRAL SOLUBLE UBIQUITIN IS INCREASED IN PATIENTS WITH ALZHEIMER'S DISEASE 184
Probing the origin of the toxicity of oligomeric aggregates of α-synuclein with antibodies 182
Quantitative assessment of the degradation of aggregated TDP-43 mediated by the ubiquitin proteasome system and macroautophagy 181
Squalamine and its derivatives modulate the aggregation of amyloid-β and α-synuclein and suppress the toxicity of their oligomers 181
Exploring the release of toxic oligomers from α-synuclein fibrils with antibodies and sted microscopy 180
Extracellular chaperones prevent Aβ42-induced toxicity in rat brains 178
CRYSTALLISATION AND PRELIMINARY X-RAY ANALYSIS OF THE 'COMMON TYPE' ACYLPHOSPHATASE 177
Plasma Membrane Injury Depends on Bilayer Lipid Composition in Alzheimer’s Disease 177
Membrane lipid composition and its physicochemical properties define cell vulnerability to aberrant protein oligomers 176
Structure-toxicity relationship in intermediate fibrils from lα-Synuclein condensates 175
Protective effect of new S-acylglutathione derivatives against amyloid induced oxidative stress 175
Early changes induced in the left ventricle by pressure overload. An experimental study on swine heart. 175
Quantitative Attribution of the Protective Effects of Aminosterols against Protein Aggregates to Their Chemical Structures and Ability to Modulate Biological Membranes 174
Glutathione level is altered in lymphoblasts from patients with familial Alzheimer's disease 174
Aβ oligomers dysregulate calcium homeostasis by mechanosensitive activation of AMPA and NMDA receptors. 172
Transthyretin suppresses the toxicity of oligomers formed by misfolded proteins in vitro 171
Lack of SOD1 gene mutations and activity alterations in two Italian families with amyotrophic lateral sclerosis 171
Light-responsive nanocomposite sponges for on demand chemical release with high spatial and dosage control 169
Glutathione levels in lymphoblasts from patients with familial Alzheimer's disease linked to presenilin genes 167
The amyloid-cell membrane system. The interplay between the biophysical features of oligomers/fibrils and cell membrane defines amyloid toxicity 167
Oxidative stress and reduced antioxidant defenses in peripheral cells from familial Alzheimer's patients. 165
Biological membranes as protein aggregation matrices and targets of amyloid toxicity 165
Differing molecular mechanisms appear to underlie early toxicity of pre-fibrillar HypF-N aggregates to different cell types 164
Chaperones suppress protein oligomer toxicity: Insight into the molecular mechanism of action 163
Misfolded protein oligomers induce an increase of intracellular Ca2+ causing an escalation of reactive oxidative species 161
Alzheimer’s disease lymphoblasts: evidence for oxidative stress 161
Amyloid cytotoxicity depends on membrane lipid composition in Alzheimer's disease 161
Alzheimer Disease detection from Raman spectroscopy of the cerebrospinal fluid via topological machine learning 156
Soluble Prion peptide 107–120 protects neuroblastoma SH-SY5Y cells against oligomers associated with Alzheimer’s disease 156
Trodusquemine displaces protein misfolded oligomers from cell membranes and abrogates their cytotoxicity through a generic mechanism 156
Replicating neuroblastoma cells in different cell cycle phases display different vulnerability to amyloid toxicity 155
Interaction between acylphosphatase and SERCA in SH-SY5Y cells 155
Totale 22.930
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Categoria #
all - tutte 69.661
article - articoli 0
book - libri 0
conference - conferenze 0
curatela - curatele 0
other - altro 0
patent - brevetti 0
selected - selezionate 0
volume - volumi 0
Totale 69.661
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Totale Lug Ago Sett Ott Nov Dic Gen Feb Mar Apr Mag Giu
2021/2022792 0 99 69 23 23 32 35 56 45 45 138 227
2022/20232.614 193 481 150 263 189 432 325 132 259 45 77 68
2023/20241.044 47 112 130 48 65 186 42 219 13 72 59 51
2024/20256.391 174 652 397 982 1.977 830 107 354 267 162 246 243
2025/20267.460 787 961 605 544 834 343 941 366 503 530 195 851
2026/2027400 230 170 0 0 0 0 0 0 0 0 0 0
Totale 26.764