CECCHI, CRISTINA
 Distribuzione geografica
Salva come PNG Salva come JPEG
Continente #
NA - Nord America 11.071
EU - Europa 10.336
AS - Asia 4.622
SA - Sud America 628
Continente sconosciuto - Info sul continente non disponibili 181
AF - Africa 120
OC - Oceania 87
Totale 27.045
Salva come PNG Salva come JPEG
Nazione #
US - Stati Uniti d'America 10.867
PL - Polonia 4.224
RU - Federazione Russa 2.284
IT - Italia 1.459
SG - Singapore 1.303
CN - Cina 1.159
HK - Hong Kong 645
SE - Svezia 530
IE - Irlanda 514
VN - Vietnam 505
BR - Brasile 486
KR - Corea 372
DE - Germania 300
FI - Finlandia 241
FR - Francia 209
IN - India 198
UA - Ucraina 148
GB - Regno Unito 145
CA - Canada 128
ID - Indonesia 84
AU - Australia 74
CH - Svizzera 73
NL - Olanda 73
JO - Giordania 63
JP - Giappone 46
AR - Argentina 44
BD - Bangladesh 44
TR - Turchia 41
MX - Messico 36
ES - Italia 34
CO - Colombia 23
CI - Costa d'Avorio 22
EC - Ecuador 22
NG - Nigeria 22
IQ - Iraq 21
ZA - Sudafrica 18
BE - Belgio 16
VE - Venezuela 16
AE - Emirati Arabi Uniti 14
RO - Romania 14
UZ - Uzbekistan 14
NZ - Nuova Zelanda 13
PK - Pakistan 13
PY - Paraguay 13
IR - Iran 12
CL - Cile 11
MA - Marocco 11
MY - Malesia 11
SA - Arabia Saudita 11
JM - Giamaica 10
PH - Filippine 9
SC - Seychelles 9
SK - Slovacchia (Repubblica Slovacca) 9
AZ - Azerbaigian 8
EG - Egitto 8
IL - Israele 8
AT - Austria 7
CR - Costa Rica 7
LT - Lituania 7
AL - Albania 6
BJ - Benin 6
KE - Kenya 6
PE - Perù 6
TT - Trinidad e Tobago 6
TW - Taiwan 6
CZ - Repubblica Ceca 5
DZ - Algeria 5
HN - Honduras 5
PT - Portogallo 5
ET - Etiopia 4
GE - Georgia 4
HU - Ungheria 4
KG - Kirghizistan 4
OM - Oman 4
BG - Bulgaria 3
BH - Bahrain 3
BO - Bolivia 3
DK - Danimarca 3
GR - Grecia 3
LU - Lussemburgo 3
MU - Mauritius 3
NP - Nepal 3
PR - Porto Rico 3
TH - Thailandia 3
UY - Uruguay 3
BA - Bosnia-Erzegovina 2
EE - Estonia 2
EU - Europa 2
GA - Gabon 2
GT - Guatemala 2
HR - Croazia 2
IS - Islanda 2
KZ - Kazakistan 2
LB - Libano 2
LV - Lettonia 2
MM - Myanmar 2
NI - Nicaragua 2
NO - Norvegia 2
PA - Panama 2
RS - Serbia 2
Totale 26.847
Salva come PNG Salva come JPEG
Città #
Warsaw 4.220
Santa Clara 2.302
Ashburn 1.366
Singapore 940
Fairfield 762
Chandler 630
Hong Kong 545
Dublin 512
San Jose 486
Woodbridge 359
Seoul 356
Seattle 313
Cambridge 312
Houston 305
Council Bluffs 296
Milan 281
Wilmington 273
Beijing 249
Hefei 242
Jacksonville 207
Florence 191
Altamura 170
Lawrence 146
Los Angeles 142
The Dalles 139
Ann Arbor 134
Ho Chi Minh City 132
Princeton 127
Rome 116
Lauterbourg 114
Boston 112
Buffalo 104
Boardman 101
Munich 100
Hanoi 97
Mumbai 80
Phoenix 79
Helsinki 78
Dallas 76
Moscow 76
Dong Ket 72
Melbourne 71
New York 69
Shanghai 66
Jakarta 65
Dearborn 63
Bremen 58
San Diego 47
Medford 45
Pune 45
Paris 44
Kent 43
Turku 43
Bern 39
São Paulo 38
Naples 34
Tokyo 30
Lappeenranta 29
Orem 28
Bologna 26
Montreal 26
West Jordan 26
Clifton 25
Toronto 24
Columbus 23
Izmir 23
Abidjan 22
Abuja 22
Guangzhou 22
Redondo Beach 22
Norwalk 21
Turin 21
Chennai 20
Chicago 20
London 20
Atlanta 19
Barcelona 19
Haiphong 18
Washington 18
Frankfurt am Main 17
Brooklyn 16
Miano 16
Verona 16
Denver 15
Figino 15
Bari 14
Da Nang 14
Stockholm 14
Bengaluru 13
Falls Church 13
Hillsboro 13
Mexico City 13
Tashkent 13
Basel 12
Milwaukee 12
Palermo 12
Rio de Janeiro 12
Venice 12
Brussels 11
Groningen 11
Totale 18.920
Salva come PNG Salva come JPEG
Nome #
A causative link between the structure of aberrant protein oligomers and their toxicity 488
Biochemical changes and their relationship with morphological and functional finding in pig heart subjected to lasting volume-overload: a possible role of Acylphosphatase in the regulation of sarcoplasmic reticulum calcium pump. 343
SIRT1 modulates MAPK pathways in ischemic-reperfused cardiomyocytes 339
Seladin-1/dhcr24 protects neuroblastoma cells against aβ toxicity by increasing membrane cholesterol content 339
Protective effect of the PARP-1 inhibitor PJ34 in hypoxic-reoxygenated cardiomyoblasts 337
TDP-43 inclusion bodies formed in bacteria are structurally amorphous, non-amyloid and inherently toxic to neuroblastoma cells 335
Structural basis of membrane disruption and cellular toxicity by α-synuclein oligomers 330
SIRT1 regulates MAPK pathways in vitiligo skin: insight into the molecular pathways of cell survival 330
A natural product inhibits the initiation of α-synuclein aggregation and suppresses its toxicity 329
Increased susceptibility to amyloid toxicity in familial Alzheimer's fibroblasts 328
Binding affinity of amyloid oligomers to cellular membranes is a generic indicator of cellular dysfunction in protein misfolding diseases 327
Membrane cholesterol enrichment prevents Abeta-induced oxidative stress in Alzheimer's fibroblasts. 319
Soluble Oligomers Require a Ganglioside to Trigger Neuronal Calcium Overload 317
Lipid Rafts Mediate Amyloid-induced Calcium Dyshomeostasis and Oxidative Stress in Alzheimer's Disease. 317
Quantification of the Relative Contributions of Loss-of function and Gain-of-function Mechanisms in TAR DNA-binding Protein 43 (TDP-43) Proteinopathies 316
Effect of molecular chaperones on aberrant protein oligomers in vitro: super- versus sub-stoichiometric chaperone concentrations 315
Destabilisation, aggregation, toxicity and cytosolic mislocalisation of nucleophosmin regions associated with acute myeloid leukemia 315
TDP-43 inclusion bodies formed in bacteria are structurally amorphous, non-amyloid and inherently toxic to neuroblastoma cells 315
TDP-43 inclusion bodies formed in bacteria are structurally amorphous, non-amyloid and inherently toxic to neuroblastoma cells 307
Patterns of cell death triggered in two different cell lines by HypF-N prefibrillar aggregates. 303
Single molecule experiments emphasize GM1 as a key player of the different cytotoxicity of structurally distinct Aβ1-42 oligomers 302
Curcumin protects cardiac cells against ischemia-reperfusion injury: effects on oxidative stress, NF-kappaB, and JNK pathways 301
Interaction of toxic and non-toxic HypF-N oligomers with lipid bilayers investigated at high resolution with atomic force microscopy 299
Toxic HypF-N oligomers selectively bind the plasma membrane to impair cell adhesion capability 282
Glutathione intake promotes longevity through the activation of SIR-2.1 and DAF-16 (FoxO) pathway in C. elegans 278
Nucleophosmin contains amyloidogenic regions that are able to form toxic aggregates under physiological conditions 273
Acylphosphatase levels in Alzheimer's disease cultured skin fibroblasts 267
S-linolenoyl glutathione intake extends life-span and stress resistance via Sir-2.1 upregulation in Caenorhabditis elegans 267
α-Synuclein oligomers and fibrils: partners in crime in synucleinopathies 264
Poly(ADP-ribose) polymerase activation and cell injury in the course of rat heart heterotopic transplantation. 262
A PEPTIDE FRACTION FROM FACTOR VIII REDUCES PKC ACTIVITY IN CULTURED ENDOTHELIAL CELLS 261
Molecular links between aberrant protein oligomers and neurodegeneration in Alzheimer’s disease 261
Multistep Inhibition of α‑Synuclein Aggregation and Toxicity in Vitro and in Vivo by Trodusquemine 255
The acute myeloid leukemia-associated nucleophosmin 1 gene mutations dictate amyloidogenicity of the C-terminal domain 254
Single particle tracking to study the binding of protein misfolded oligomer to membrane ganglioside GM1 252
The toxicity of misfolded protein oligomers is independent of their secondary structure 248
Partial Failure of Proteostasis Systems Counteracting TDP-43 Aggregates in Neurodegenerative Diseases 248
ALTERATION OF FREE CALCIUM LEVELS AND ACYLPHOSPHATASE MUSCULAR ISOENZYME IN CULTURED DYSTROPHIC SKIN FIBROBLASTS 247
Acylphosphatase overexpression triggers SH-SY5Y differentiation towards neuronal phenotype. 238
Beneficial Effects of Poly (ADP-ribose) Polymerase Inhibition Against the Reperfusion Injury in Heart Transplantation 235
Capturing Aβ42 aggregation in the cell 231
Lipid rafts are primary mediators of amyloid oxidative attack on plasma membrane 229
ALTERATION OF ACYLPHOSPHATASE LEVELS IN FAMILIAL ALZHEIMER'S DISEASE FIBROBLASTS WITH PRESENILIN GENE MUTATIONS 227
Nanoscopic insights into the surface conformation of neurotoxic amyloid b oligomers 223
Identification of Novel 1,3,5-Triphenylbenzene Derivative Compounds as Inhibitors of Hen Lysozyme Amyloid Fibril Formation 222
Trodusquemine enhances Aβ42 aggregation but suppresses its toxicity by displacing oligomers from cell membranes 218
Amyloid fibrils act as a reservoir of soluble oligomers, the main culprits in protein deposition diseases 212
ALTERATION OF INTRACELLULAR FREE CALCIUM AND ACYLPHOSPHATASE LEVELS IN DIFFERENTIATING SH-SY5Y NEUROBLASTOMA CELLS 211
A protective role for lipid raft cholesterol againsy amyloid-induced membrane damage in human neuroblastoma cells 209
Protective Properties of Novel S-Acyl-Glutathione Thioesters Against Ultraviolet-induced Oxidative Stress 207
Over-expression of amyloid precursor protein in HEK cells alters P53 conformational state and protects against doxorubicin. 205
Biophysical characterization of full-length TAR DNA-binding protein (TDP-43) phase separation. 203
Sphingosine 1-phosphate attenuates neuronal dysfunction induced by amyloid-β oligomers through endocytic internalization of NMDA receptors 203
Differentiation increases the resistance of neuronal cells to amyloid toxicity 203
A Complex Equilibrium among Partially Unfolded Conformations in Monomeric Transthyretin 203
A comparison of the biochemical modifications caused by toxic and non-toxic protein oligomers in cells 200
An in situ and in vitro investigation of cytoplasmic TDP-43 inclusions reveals the absence of a clear amyloid signature 197
Molecular mechanisms used by chaperones to reduce the toxicity of aberrant protein oligomers 197
Un nuovo metodo per il dosaggio reflettometrico della emoglobina totale 195
A quantitative biology approach correlates neuronal toxicity with the largest inclusions of TDP-43 193
Generation of reactive oxygen species by beta amyloid fibrils and oligomers involves different intra/extracellular pathways. 193
Neuronal differentiation of human mesenchymal stromal cells increases their resistance to Aβ42 aggregate toxicity. 193
APP and Bace1: Differential effect of cholesterol enrichment on processing and plasma membrane mobility 189
DROSOPHILA MELANOGASTER ACYLPHOSPHATASE: A COMMON ANCESTOR FOR ACYLPHOSPHATASE ISOENZYMES OF VERTEBRATE SPECIES 189
Targeting pathological amyloid aggregates with conformation-sensitive antibodies 189
Novel S-acyl glutathione derivatives prevent amyloid oxidative stress and cholinergic dysfunction in Alzheimer disease models. Free Radic Biol Med. 189
Glycosaminoglycans (GAGs) Suppress the Toxicity of HypF-N Prefibrillar Aggregates 188
Insights into the molecular basis of the differing susceptibility of varying cell types to the toxicity of amyloid aggregates 186
CEREBRAL SOLUBLE UBIQUITIN IS INCREASED IN PATIENTS WITH ALZHEIMER'S DISEASE 185
Quantitative assessment of the degradation of aggregated TDP-43 mediated by the ubiquitin proteasome system and macroautophagy 184
Probing the origin of the toxicity of oligomeric aggregates of α-synuclein with antibodies 184
Squalamine and its derivatives modulate the aggregation of amyloid-β and α-synuclein and suppress the toxicity of their oligomers 183
Exploring the release of toxic oligomers from α-synuclein fibrils with antibodies and sted microscopy 181
CRYSTALLISATION AND PRELIMINARY X-RAY ANALYSIS OF THE 'COMMON TYPE' ACYLPHOSPHATASE 178
Extracellular chaperones prevent Aβ42-induced toxicity in rat brains 178
Plasma Membrane Injury Depends on Bilayer Lipid Composition in Alzheimer’s Disease 178
Membrane lipid composition and its physicochemical properties define cell vulnerability to aberrant protein oligomers 178
Structure-toxicity relationship in intermediate fibrils from lα-Synuclein condensates 177
Early changes induced in the left ventricle by pressure overload. An experimental study on swine heart. 177
Quantitative Attribution of the Protective Effects of Aminosterols against Protein Aggregates to Their Chemical Structures and Ability to Modulate Biological Membranes 176
Protective effect of new S-acylglutathione derivatives against amyloid induced oxidative stress 176
Glutathione level is altered in lymphoblasts from patients with familial Alzheimer's disease 175
Lack of SOD1 gene mutations and activity alterations in two Italian families with amyotrophic lateral sclerosis 174
Aβ oligomers dysregulate calcium homeostasis by mechanosensitive activation of AMPA and NMDA receptors. 173
Transthyretin suppresses the toxicity of oligomers formed by misfolded proteins in vitro 172
Glutathione levels in lymphoblasts from patients with familial Alzheimer's disease linked to presenilin genes 171
Light-responsive nanocomposite sponges for on demand chemical release with high spatial and dosage control 171
Differing molecular mechanisms appear to underlie early toxicity of pre-fibrillar HypF-N aggregates to different cell types 169
The amyloid-cell membrane system. The interplay between the biophysical features of oligomers/fibrils and cell membrane defines amyloid toxicity 169
Oxidative stress and reduced antioxidant defenses in peripheral cells from familial Alzheimer's patients. 168
Chaperones suppress protein oligomer toxicity: Insight into the molecular mechanism of action 167
Biological membranes as protein aggregation matrices and targets of amyloid toxicity 166
Alzheimer’s disease lymphoblasts: evidence for oxidative stress 164
Misfolded protein oligomers induce an increase of intracellular Ca2+ causing an escalation of reactive oxidative species 163
Amyloid cytotoxicity depends on membrane lipid composition in Alzheimer's disease 163
Alzheimer Disease detection from Raman spectroscopy of the cerebrospinal fluid via topological machine learning 157
Replicating neuroblastoma cells in different cell cycle phases display different vulnerability to amyloid toxicity 157
Interaction between acylphosphatase and SERCA in SH-SY5Y cells 157
Calcium dyshomeostasis in Alzheimer’s disease pathogenesis 157
Soluble Prion peptide 107–120 protects neuroblastoma SH-SY5Y cells against oligomers associated with Alzheimer’s disease 157
Totale 23.132
Salva come PNG Salva come JPEG
Categoria #
all - tutte 70.576
article - articoli 0
book - libri 0
conference - conferenze 0
curatela - curatele 0
other - altro 0
patent - brevetti 0
selected - selezionate 0
volume - volumi 0
Totale 70.576
Salva come PNG Salva come JPEG


Totale Lug Ago Sett Ott Nov Dic Gen Feb Mar Apr Mag Giu
2021/2022693 0 0 69 23 23 32 35 56 45 45 138 227
2022/20232.614 193 481 150 263 189 432 325 132 259 45 77 68
2023/20241.044 47 112 130 48 65 186 42 219 13 72 59 51
2024/20256.391 174 652 397 982 1.977 830 107 354 267 162 246 243
2025/20267.460 787 961 605 544 834 343 941 366 503 530 195 851
2026/2027681 230 193 258 0 0 0 0 0 0 0 0 0
Totale 27.045