BUA, SILVIA
 Distribuzione geografica
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Continente #
NA - Nord America 3.346
EU - Europa 1.879
AS - Asia 623
AF - Africa 48
SA - Sud America 7
OC - Oceania 1
Totale 5.904
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Nazione #
US - Stati Uniti d'America 3.338
RU - Federazione Russa 1.016
IE - Irlanda 254
HK - Hong Kong 220
IT - Italia 193
SG - Singapore 163
PL - Polonia 155
SE - Svezia 114
CN - Cina 106
IN - India 77
GB - Regno Unito 38
FI - Finlandia 37
EG - Egitto 30
DE - Germania 27
JO - Giordania 17
CH - Svizzera 14
BE - Belgio 10
VN - Vietnam 9
CI - Costa d'Avorio 8
ES - Italia 7
TW - Taiwan 7
CA - Canada 6
DZ - Algeria 6
UA - Ucraina 6
TR - Turchia 5
BR - Brasile 4
IR - Iran 4
JP - Giappone 4
KR - Corea 4
PK - Pakistan 4
FR - Francia 3
IQ - Iraq 3
AR - Argentina 2
CD - Congo 2
MX - Messico 2
AU - Australia 1
CO - Colombia 1
LT - Lituania 1
LV - Lettonia 1
MU - Mauritius 1
NL - Olanda 1
PT - Portogallo 1
RO - Romania 1
SC - Seychelles 1
Totale 5.904
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Città #
Santa Clara 957
Fairfield 375
Dublin 253
Ashburn 222
Woodbridge 173
Warsaw 153
Seattle 148
Houston 144
Chandler 142
Cambridge 141
Hong Kong 140
Singapore 126
Wilmington 112
Moscow 109
Ann Arbor 83
Lawrence 78
Altamura 74
Princeton 61
Mumbai 57
Boston 45
Florence 43
Helsinki 28
San Diego 26
Beijing 22
Cairo 20
Shanghai 19
West Jordan 18
Boardman 16
Bern 14
Buffalo 12
Falls Church 12
Medford 12
Washington 11
Kent 10
Brussels 9
Dong Ket 9
London 9
Norwalk 9
Redwood City 9
Abidjan 8
Gavirate 8
Hillsboro 8
New York 8
Yubileyny 7
Belfast 6
Giza 5
Pune 5
Rome 5
Toronto 5
Andover 4
Cagliari 4
Guangzhou 4
Los Angeles 4
Barcelona 3
Constantine 3
Detroit 3
Frankfurt am Main 3
Istanbul 3
Meftah 3
Messina 3
Misano Adriatico 3
New Delhi 3
Romola 3
Salamanca 3
Sulaymaniyah 3
Taipei 3
Westfield 3
Castelliri 2
Città Sant'Angelo 2
Delhi 2
Falkenstein 2
Gujranwala 2
Hangzhou 2
João Pessoa 2
La Paz 2
Lahore 2
Laurel 2
Mar del Plata 2
Noida 2
Prescot 2
Qom 2
Quanzhou 2
Royersford 2
San Jose 2
Scandicci 2
Seoul 2
São Paulo 2
Turku 2
Vadodara 2
Wandsworth 2
Wuhan 2
Wuxi 2
Acton 1
Bethesda 1
Bitam 1
Bogotá 1
Buonabitacolo 1
Centereach 1
Chang-hua 1
Chennai 1
Totale 4.082
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Nome #
Hybrid Pharmacophores as Carbonic Anhydrase Inhibitors 208
Novel diamide-based benzenesulfonamides as selective carbonic anhydrase ix inhibitors endowed with antitumor activity: Synthesis, biological evaluation and in silico insights 150
2-Benzylpiperazine: a new scaffold for potent human Carbonic Anhydrase inhibitors. Synthesis, enzyme inhibition, enantioselectivity, computational and crystallographic studies and in vivo activity for a new class of intraocular pressure lowering agents. 145
Novel sulfamide-containing compounds as selective carbonic anhydrase i inhibitors 139
Design and Synthesis of Novel Nonsteroidal Anti-Inflammatory Drugs and Carbonic Anhydrase Inhibitors Hybrids (NSAIDs-CAIs) for the Treatment of Rheumatoid Arthritis 139
Advances in New Psychoactive Substances Identification: The U.R.I.To.N Consortium 137
Discovery of β-Adrenergic Receptors Blocker-Carbonic Anhydrase Inhibitor Hybrids for Multitargeted Antiglaucoma Therapy 131
Dual P-glycoprotein and CA XII inhibitors: A new strategy to reverse the P-gp Mediated Multidrug Resistance (MDR) in cancer cells y 122
Benzenesulfonamide bearing imidazothiadiazole and thiazolotriazole scaffolds as potent tumor associated human carbonic anhydrase IX and XII inhibitors 120
Carbonic anhydrase inhibitors based on sorafenib scaffold: Design, synthesis, crystallographic investigation and effects on primary breast cancer cells 116
Inhibition of Malassezia globosa carbonic anhydrase with phenols 114
Discovery of New Sulfonamide Carbonic Anhydrase IX Inhibitors Incorporating Nitrogenous Bases 112
Novel 6- and 7-Substituted Coumarins with Inhibitory Action against Lipoxygenase and Tumor-Associated Carbonic Anhydrase IX 110
Investigating the antiplasmodial activity of primary sulfonamide compounds identified in open source malaria data 108
Sulfonamides incorporating piperazine bioisosteres as potent human carbonic anhydrase I, II, IV and IX inhibitors 105
Anticancer effects of new dibenzenesulfonamides by inducing apoptosis and autophagy pathways and their carbonic anhydrase inhibitory effects on hCA I, hCA II, hCA IX, hCA XII isoenzymes 105
Synthesis and carbonic anhydrase inhibitory effects of new N-glycosylsulfonamides incorporating the phenol moiety 104
Novel indolin-2-one-based sulfonamides as carbonic anhydrase inhibitors: Synthesis, in vitro biological evaluation against carbonic anhydrases isoforms I, II, IV and VII and molecular docking studies 104
Synthesis of novel dipeptide sulfonamide conjugates with effective carbonic anhydrase I, II, IX, and XII inhibitory properties 93
Sulfonamide Inhibitors of Human Carbonic Anhydrases Designed through a Three-Tails Approach: Improving Ligand/Isoform Matching and Selectivity of Action 93
3-Hydrazinoisatin-based benzenesulfonamides as novel carbonic anhydrase inhibitors endowed with anticancer activity: Synthesis, in vitro biological evaluation and in silico insights 91
Synthesis, structure and bioactivity of primary sulfamate-containing natural products 87
Enhancement of the tail hydrophobic interactions within the carbonic anhydrase IX active site via structural extension: Design and synthesis of novel N-substituted isatins-SLC-0111 hybrids as carbonic anhydrase inhibitors and antitumor agents 85
Synthesis, biological evaluation and in silico studies with 4-benzylidene-2-phenyl-5(4H)-imidazolone-based benzenesulfonamides as novel selective carbonic anhydrase IX inhibitors endowed with anticancer activity 83
P-glycoprotein and carbonic anhydrases hybrid inhibitors: a new strategy to reverse multidrug resistance (MDR) in cancer cells 83
Continued exploration and tail approach synthesis of benzenesulfonamides containing triazole and dual triazole moieties as carbonic anhydrase I, II, IV and IX inhibitors 81
APPLICATION OF LINEAR EQUATIONS DECONVOLUTION ANALYSIS (LEDA) ALGORITHM IN ION TRAP MASS SPECTROMETRY: RESOLUTION OF ISOMERIC PAIRS OF CARBONIC ANHYDRASE AND CYCLOOXYGENASE HYBRIDS INHIBITORS 80
Synthesis, biological and molecular dynamics investigations with a series of triazolopyrimidine/triazole-based benzenesulfonamides as novel carbonic anhydrase inhibitors 78
Calixarenes Incorporating Sulfonamide Moieties: Versatile Ligands for Carbonic Anhydrases Inhibition 76
Resolution of co-eluting isomers of anti-inflammatory drugs conjugated to carbonic anhydrase inhibitors from plasma in liquid chromatography by energy-resolved tandem mass spectrometry 73
Discovery of benzenesulfonamide derivatives as carbonic anhydrase inhibitors with effective anticonvulsant action: Design, synthesis, and pharmacological evaluation 73
Improving the carbonic anhydrase inhibition profile of the sulfamoylphenyl pharmacophore by attachment of carbohydrate moieties 71
Inhibition studies on a panel of human carbonic anhydrases with N1-substituted secondary sulfonamides incorporating thiazolinone or imidazolone-indole tails 68
Synthesis, biological evaluation and in silico modelling studies of 1,3,5-trisubstituted pyrazoles carrying benzenesulfonamide as potential anticancer agents and selective cancer-associated hCA IX isoenzyme inhibitors 67
Ninhydrins inhibit carbonic anhydrases directly binding to the metal ion 64
"a Sweet Combination": Developing Saccharin and Acesulfame K Structures for Selectively Targeting the Tumor-Associated Carbonic Anhydrases IX and XII 64
Activation of human α-carbonic anhydrase isoforms I, II, IV and VII with bis-histamine schiff bases and bis-spinaceamine substituted derivatives 64
Natural Polyphenols Selectively Inhibit β-Carbonic Anhydrase from the Dandruff-Producing Fungus Malassezia globosa: Activity and Modeling Studies 58
Phenyl(thio)phosphon(amid)ate Benzenesulfonamides as Potent and Selective Inhibitors of Human Carbonic Anhydrases II and VII Counteract Allodynia in a Mouse Model of Oxaliplatin-Induced Neuropathy 57
Carbonic anhydrase inhibitors as diuretics 56
Discovery of Potent Dual-Tailed Benzenesulfonamide Inhibitors of Human Carbonic Anhydrases Implicated in Glaucoma and in Vivo Profiling of Their Intraocular Pressure-Lowering Action 55
Mono- and di-thiocarbamate inhibition studies of the δ-carbonic anhydrase TweCAδ from the marine diatom Thalassiosira weissflogii 53
The three-tails approach as a new strategy to improve selectivity of action of sulphonamide inhibitors against tumour-associated carbonic anhydrase IX and XII 52
Zeta-carbonic anhydrases show CS2 hydrolase activity: A new metabolic carbon acquisition pathway in diatoms? 48
The effect of substituted benzene-sulfonamides and clinically licensed drugs on the catalytic activity of cynt2, a carbonic anhydrase crucial for escherichia coli life cycle 47
Synthesis of novel benzenesulfamide derivatives with inhibitory activity against human cytosolic carbonic anhydrase I and II and Vibrio cholerae α- and β-class enzymes 46
Carbonic Anhydrase Inhibition Activities of Schiff’s Bases Based on Quinazoline-Linked Benzenesulfonamide 44
Carbonic anhydrase I, II, IV and IX inhibition with a series of 7-amino-3,4-dihydroquinolin-2(1H)-one derivatives 44
Hypoxia-activated prodrug derivatives of carbonic anhydrase inhibitors in benzenesulfonamide series: Synthesis and biological evaluation 44
Activation Studies of the β-Carbonic Anhydrase from the Pathogenic Protozoan Entamoeba histolytica with Amino Acids and Amines 43
Biological evaluation, radiosensitizing activity and structural insights of novel halogenated quinazoline-sulfonamide conjugates as selective human carbonic anhydrases IX/XII inhibitors 42
S-substituted 2-mercaptoquinazolin-4(3H)-one and 4-ethylbenzensulfonamides act as potent and selective human carbonic anhydrase IX and XII inhibitors 42
Benzenesulfonamides incorporating nitrogenous bases show effective inhibition of β-carbonic anhydrases from the pathogenic fungi Cryptococcus neoformans, Candida glabrata and Malassezia globosa 41
Benzyl alcohol inhibits carbonic anhydrases by anchoring to the zinc coordinated water molecule 41
Exploring structure-activity relationship of S-substituted 2-mercaptoquinazolin-4(3H)-one including 4-ethylbenzenesulfonamides as human carbonic anhydrase inhibitors 41
Biochemical and Structural Insights into Carbonic Anhydrase XII/Fab6A10 Complex 40
Escherichia coli γ-carbonic anhydrase: characterisation and effects of simple aromatic/heterocyclic sulphonamide inhibitors 39
STABILITY STUDY IN PLASMA OF NOVEL ESTER-LINKED NSAID - CARBONIC ANHYDRASE INHIBITOR HYBRIDS 39
Novel 2-substituted-benzimidazole-6-sulfonamides as carbonic anhydrase inhibitors: synthesis, biological evaluation against isoforms I, II, IX and XII and molecular docking studies 39
Click-tailed benzenesulfonamides as potent bacterial carbonic anhydrase inhibitors for targeting Mycobacterium tuberculosis and Vibrio cholerae 37
Extending the inhibition profiles of coumarin-based compounds against human carbonic anhydrases: Synthesis, biological, and in silico evaluation 36
Structural and biochemical characterization of novel carbonic anhydrases from Phaeodactylum tricornutum Jin Shengyang 36
Novel synthesized SLC-0111 thiazole and thiadiazole analogues: Determination of their carbonic anhydrase inhibitory activity and molecular modeling studies 35
Design, synthesis, and carbonic anhydrase inhibition activity of benzenesulfonamide-linked novel pyrazoline derivatives 35
Benzothiadiazinone-1,1-Dioxide Carbonic Anhydrase Inhibitors Suppress the Growth of Drug-Resistant Mycobacterium tuberculosis Strains 35
New anthranilic acid-incorporating N-benzenesulfonamidophthalimides as potent inhibitors of carbonic anhydrases I, II, IX, and XII: Synthesis, in vitro testing, and in silico assessment 35
3-Aminobenzenesulfonamides incorporating acylthiourea moieties selectively inhibit the tumor-associated carbonic anhydrase isoform IX over the off-target isoforms I, II and IV 34
Iodoquinazolinones bearing benzenesulfonamide as human carbonic anhydrase I, II, IX and XII inhibitors: Synthesis, biological evaluation and radiosensitizing activity 33
Synthesis and comparative carbonic anhydrase inhibition of new Schiff's bases incorporating benzenesulfonamide, methanesulfonamide, and methylsulfonylbenzene scaffolds 33
Pyrrolo and pyrrolopyrimidine sulfonamides act as cytotoxic agents in hypoxia via inhibition of transmembrane carbonic anhydrases 32
Discovery of new ureido benzenesulfonamides incorporating 1,3,5-triazine moieties as carbonic anhydrase I, II, IX and XII inhibitors 32
Novel 8-Substituted Coumarins That Selectively Inhibit Human Carbonic Anhydrase IX and XII 32
Comparison of the Anion Inhibition Profiles of the α-CA Isoforms (SpiCA1, SpiCA2 and SpiCA3) from the Scleractinian Coral Stylophora pistillata 32
Carbonic Anhydrase XII Inhibitors Overcome Temozolomide Resistance in Glioblastoma 32
Synthesis of some N-aroyl-2-oxindole benzenesulfonamide conjugates with carbonic anhydrase inhibitory activity 32
Sulphonamide inhibition profile of Staphylococcus aureus β-carbonic anhydrase 32
Vanillin enones as selective inhibitors of the cancer associated carbonic anhydrase isoforms IX and XII. The out of the active site pocket for the design of selective inhibitors? 31
Novel hydrazido benzenesulfonamides-isatin conjugates: Synthesis, carbonic anhydrase inhibitory activity and molecular modeling studies 31
Insights into the effect of elaborating coumarin-based aryl enaminones with sulfonamide or carboxylic acid functionality on carbonic anhydrase inhibitory potency and selectivity 31
The production and biochemical characterization of α-carbonic anhydrase from Lactobacillus rhamnosus GG 30
Synthesis and biological evaluation of novel N,N'-diaryl cyanoguanidines acting as potent and selective carbonic anhydrase II inhibitors 30
Comprehensive study on potent and selective carbonic anhydrase inhibitors: Synthesis, bioactivities and molecular modelling studies of 4-(3-(2-arylidenehydrazine-1-carbonyl)-5-(thiophen-2-yl)-1H-pyrazole-1-yl) benzenesulfonamides 30
Discovery of novel 1,3-diaryltriazene sulfonamides as carbonic anhydrase I, II, VII, and IX inhibitors 29
Synthesis and selective inhibitory effects of some 2-oxindole benzenesulfonamide conjugates on human carbonic anhydrase isoforms CA I, CA II, CA IX and CAXII 29
Synthesis of novel benzenesulfonamide bearing 1,2,3-triazole linked hydroxy-trifluoromethylpyrazolines and hydrazones as selective carbonic anhydrase isoforms IX and XII inhibitors 29
Discovery of Potent Carbonic Anhydrase Inhibitors as Effective Anticonvulsant Agents: Drug Design, Synthesis, and in Vitro and in Vivo Investigations 29
Diagnostic markers for glaucoma: a patent and literature review (2013-2019) 29
Synthesis and biological evaluation of novel 3-(quinolin-4-ylamino)benzenesulfonamidesAQ3 as carbonic anhydrase isoforms I and II inhibitors 28
Indole-Based Hydrazones Containing A Sulfonamide Moiety as Selective Inhibitors of Tumor-Associated Human Carbonic Anhydrase Isoforms IX and XII 28
Evaluation of sulphonamide derivatives acting as inhibitors of human carbonic anhydrase isoforms I, II and Mycobacterium tuberculosis β-class enzyme Rv3273 28
Design and synthesis of novel benzenesulfonamide containing 1,2,3-triazoles as potent human carbonic anhydrase isoforms I, II, IV and IX inhibitors 28
Synthesis, X-ray structure, in silico calculation, and carbonic anhydrase inhibitory properties of benzylimidazole metal complexes 28
Synthesis and biological evaluation of benzenesulphonamide-bearing 1,4,5-trisubstituted-1,2,3-triazoles possessing human carbonic anhydrase I, II, IV, and IX inhibitory activity 27
Design and synthesis of novel 1,3-diaryltriazene-substituted sulfonamides as potent and selective carbonic anhydrase II inhibitors 27
α-Carbonic anhydrases are strongly activated by spinaceamine derivatives 27
Investigation of carbonic anhydrase inhibitory effects and cytotoxicities of pyrazole-based hybrids carrying hydrazone and zinc-binding benzenesulfonamide pharmacophores 27
Synthesis and human/bacterial carbonic anhydrase inhibition with a series of sulfonamides incorporating phthalimido moieties 27
Discovery of potent nucleotide pyrophosphatase/phosphodiesterase3 (NPP3) inhibitors with ancillary carbonic anhydrase inhibition for cancer (immuno)therapy 26
Design, synthesis and biological evaluation of novel ureido benzenesulfonamides incorporating 1,3,5-triazine moieties as potent carbonic anhydrase IX inhibitors 25
Sulfonamide Inhibition Studies of a New β-Carbonic Anhydrase from the Pathogenic Protozoan Entamoeba histolytica 24
Totale 6.005
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Categoria #
all - tutte 23.249
article - articoli 0
book - libri 0
conference - conferenze 0
curatela - curatele 0
other - altro 0
patent - brevetti 0
selected - selezionate 0
volume - volumi 0
Totale 23.249
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Totale Lug Ago Sett Ott Nov Dic Gen Feb Mar Apr Mag Giu
2019/2020552 0 0 0 0 86 83 86 82 84 55 58 18
2020/2021518 35 43 22 43 51 64 22 36 54 91 36 21
2021/2022362 6 8 31 27 14 16 8 27 54 34 37 100
2022/2023940 102 208 49 29 55 162 118 48 62 53 26 28
2023/2024688 30 40 109 17 75 94 9 188 20 67 27 12
2024/20252.520 156 447 216 529 1.172 0 0 0 0 0 0 0
Totale 6.043