BUA, SILVIA
 Distribuzione geografica
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Continente #
NA - Nord America 5.978
AS - Asia 4.132
EU - Europa 2.936
SA - Sud America 659
Continente sconosciuto - Info sul continente non disponibili 151
AF - Africa 148
OC - Oceania 58
Totale 14.062
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Nazione #
US - Stati Uniti d'America 5.869
RU - Federazione Russa 1.369
CN - Cina 1.294
SG - Singapore 1.160
IT - Italia 580
BR - Brasile 526
HK - Hong Kong 478
KR - Corea 455
VN - Vietnam 353
IE - Irlanda 256
PL - Polonia 160
IN - India 135
SE - Svezia 123
FR - Francia 106
FI - Finlandia 93
GB - Regno Unito 75
CA - Canada 70
DE - Germania 70
AU - Australia 57
AR - Argentina 52
EG - Egitto 43
ID - Indonesia 41
BD - Bangladesh 34
EC - Ecuador 29
JP - Giappone 28
IQ - Iraq 25
NG - Nigeria 24
JO - Giordania 23
PK - Pakistan 21
ES - Italia 17
ZA - Sudafrica 17
CH - Svizzera 16
TR - Turchia 16
BJ - Benin 15
NL - Olanda 15
MA - Marocco 14
CO - Colombia 13
MX - Messico 13
UA - Ucraina 12
PY - Paraguay 11
BE - Belgio 10
VE - Venezuela 10
CI - Costa d'Avorio 9
CL - Cile 9
TW - Taiwan 9
DZ - Algeria 8
SA - Arabia Saudita 8
AL - Albania 7
PH - Filippine 7
MY - Malesia 6
PE - Perù 6
UZ - Uzbekistan 6
HN - Honduras 5
NP - Nepal 5
AE - Emirati Arabi Uniti 4
AT - Austria 4
DO - Repubblica Dominicana 4
IR - Iran 4
KE - Kenya 4
KZ - Kazakistan 4
LT - Lituania 4
AZ - Azerbaigian 3
GT - Guatemala 3
PR - Porto Rico 3
TN - Tunisia 3
XK - ???statistics.table.value.countryCode.XK??? 3
BH - Bahrain 2
BY - Bielorussia 2
CD - Congo 2
CR - Costa Rica 2
GA - Gabon 2
HR - Croazia 2
LC - Santa Lucia 2
LV - Lettonia 2
NI - Nicaragua 2
PT - Portogallo 2
RO - Romania 2
SN - Senegal 2
TH - Thailandia 2
UY - Uruguay 2
AG - Antigua e Barbuda 1
AO - Angola 1
BA - Bosnia-Erzegovina 1
BB - Barbados 1
BN - Brunei Darussalam 1
BO - Bolivia 1
BQ - ???statistics.table.value.countryCode.BQ??? 1
CW - ???statistics.table.value.countryCode.CW??? 1
CZ - Repubblica Ceca 1
DK - Danimarca 1
GD - Grenada 1
GE - Georgia 1
GM - Gambi 1
KG - Kirghizistan 1
KW - Kuwait 1
LB - Libano 1
LK - Sri Lanka 1
LU - Lussemburgo 1
MD - Moldavia 1
MK - Macedonia 1
Totale 13.904
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Città #
Santa Clara 1.668
Singapore 899
Ashburn 843
Hefei 517
Seoul 448
Hong Kong 394
Fairfield 375
Dublin 255
San Jose 250
Woodbridge 173
Warsaw 157
Seattle 152
Beijing 151
Houston 150
Chandler 142
Cambridge 141
Moscow 138
Ho Chi Minh City 134
Council Bluffs 121
Wilmington 113
Milan 107
Los Angeles 98
Lauterbourg 85
Ann Arbor 83
Lawrence 79
The Dalles 79
Altamura 74
Buffalo 63
Florence 62
Hanoi 62
Mumbai 61
Princeton 61
Helsinki 58
Kent 56
Melbourne 55
Rome 50
Boston 47
São Paulo 47
Dallas 44
Clifton 30
Boardman 29
San Diego 26
Bengaluru 25
Shanghai 24
Abuja 23
Cairo 23
Jakarta 23
New York 23
Munich 22
Tokyo 20
West Jordan 20
Rio de Janeiro 19
London 18
Chicago 16
Cotonou 15
Montreal 15
Turin 15
Turku 15
Bern 14
Guayaquil 14
Paris 14
Redondo Beach 14
Lappeenranta 13
Phoenix 13
Falls Church 12
Medford 12
Naples 12
Washington 12
Atlanta 11
Belo Horizonte 11
Brasília 11
Frankfurt am Main 11
Guangzhou 11
Haiphong 11
Hillsboro 11
Norwalk 11
Curitiba 10
Giza 10
Miano 10
Tianjin 10
Toronto 10
Abidjan 9
Brooklyn 9
Brussels 9
Casablanca 9
Dong Ket 9
Figino 9
Pune 9
Quito 9
Redwood City 9
San Francisco 9
Da Nang 8
Gavirate 8
Cape Town 7
Dhaka 7
Falkenstein 7
Ninh Bình 7
Stockholm 7
Thái Bình 7
Yubileyny 7
Totale 9.316
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Nome #
Hybrid Pharmacophores as Carbonic Anhydrase Inhibitors 349
2-Benzylpiperazine: a new scaffold for potent human Carbonic Anhydrase inhibitors. Synthesis, enzyme inhibition, enantioselectivity, computational and crystallographic studies and in vivo activity for a new class of intraocular pressure lowering agents. 286
Discovery of β-Adrenergic Receptors Blocker-Carbonic Anhydrase Inhibitor Hybrids for Multitargeted Antiglaucoma Therapy 224
Novel diamide-based benzenesulfonamides as selective carbonic anhydrase ix inhibitors endowed with antitumor activity: Synthesis, biological evaluation and in silico insights 217
Dual P-glycoprotein and CA XII inhibitors: A new strategy to reverse the P-gp Mediated Multidrug Resistance (MDR) in cancer cells y 214
Novel sulfamide-containing compounds as selective carbonic anhydrase i inhibitors 207
Advances in New Psychoactive Substances Identification: The U.R.I.To.N Consortium 201
Carbonic anhydrase inhibitors based on sorafenib scaffold: Design, synthesis, crystallographic investigation and effects on primary breast cancer cells 198
Benzenesulfonamide bearing imidazothiadiazole and thiazolotriazole scaffolds as potent tumor associated human carbonic anhydrase IX and XII inhibitors 188
Discovery of New Sulfonamide Carbonic Anhydrase IX Inhibitors Incorporating Nitrogenous Bases 180
P-glycoprotein and carbonic anhydrases hybrid inhibitors: a new strategy to reverse multidrug resistance (MDR) in cancer cells 180
Sulfonamide Inhibitors of Human Carbonic Anhydrases Designed through a Three-Tails Approach: Improving Ligand/Isoform Matching and Selectivity of Action 179
Discovery of Potent Dual-Tailed Benzenesulfonamide Inhibitors of Human Carbonic Anhydrases Implicated in Glaucoma and in Vivo Profiling of Their Intraocular Pressure-Lowering Action 178
Design and Synthesis of Novel Nonsteroidal Anti-Inflammatory Drugs and Carbonic Anhydrase Inhibitors Hybrids (NSAIDs-CAIs) for the Treatment of Rheumatoid Arthritis 176
APPLICATION OF LINEAR EQUATIONS DECONVOLUTION ANALYSIS (LEDA) ALGORITHM IN ION TRAP MASS SPECTROMETRY: RESOLUTION OF ISOMERIC PAIRS OF CARBONIC ANHYDRASE AND CYCLOOXYGENASE HYBRIDS INHIBITORS 175
Carbonic Anhydrase Inhibition Activities of Schiff’s Bases Based on Quinazoline-Linked Benzenesulfonamide 174
Sulfonamides incorporating piperazine bioisosteres as potent human carbonic anhydrase I, II, IV and IX inhibitors 171
Continued exploration and tail approach synthesis of benzenesulfonamides containing triazole and dual triazole moieties as carbonic anhydrase I, II, IV and IX inhibitors 171
3-Hydrazinoisatin-based benzenesulfonamides as novel carbonic anhydrase inhibitors endowed with anticancer activity: Synthesis, in vitro biological evaluation and in silico insights 167
Synthesis of novel dipeptide sulfonamide conjugates with effective carbonic anhydrase I, II, IX, and XII inhibitory properties 166
Novel indolin-2-one-based sulfonamides as carbonic anhydrase inhibitors: Synthesis, in vitro biological evaluation against carbonic anhydrases isoforms I, II, IV and VII and molecular docking studies 165
Anticancer effects of new dibenzenesulfonamides by inducing apoptosis and autophagy pathways and their carbonic anhydrase inhibitory effects on hCA I, hCA II, hCA IX, hCA XII isoenzymes 163
Inhibition of Malassezia globosa carbonic anhydrase with phenols 161
Novel 6- and 7-Substituted Coumarins with Inhibitory Action against Lipoxygenase and Tumor-Associated Carbonic Anhydrase IX 158
Calixarenes Incorporating Sulfonamide Moieties: Versatile Ligands for Carbonic Anhydrases Inhibition 157
Escherichia coli γ-carbonic anhydrase: characterisation and effects of simple aromatic/heterocyclic sulphonamide inhibitors 154
Biological evaluation, radiosensitizing activity and structural insights of novel halogenated quinazoline-sulfonamide conjugates as selective human carbonic anhydrases IX/XII inhibitors 151
Investigating the antiplasmodial activity of primary sulfonamide compounds identified in open source malaria data 150
"a Sweet Combination": Developing Saccharin and Acesulfame K Structures for Selectively Targeting the Tumor-Associated Carbonic Anhydrases IX and XII 150
Synthesis, structure and bioactivity of primary sulfamate-containing natural products 146
Enhancement of the tail hydrophobic interactions within the carbonic anhydrase IX active site via structural extension: Design and synthesis of novel N-substituted isatins-SLC-0111 hybrids as carbonic anhydrase inhibitors and antitumor agents 144
Resolution of co-eluting isomers of anti-inflammatory drugs conjugated to carbonic anhydrase inhibitors from plasma in liquid chromatography by energy-resolved tandem mass spectrometry 144
Synthesis, biological evaluation and in silico modelling studies of 1,3,5-trisubstituted pyrazoles carrying benzenesulfonamide as potential anticancer agents and selective cancer-associated hCA IX isoenzyme inhibitors 142
Synthesis, biological and molecular dynamics investigations with a series of triazolopyrimidine/triazole-based benzenesulfonamides as novel carbonic anhydrase inhibitors 142
Activation of human α-carbonic anhydrase isoforms I, II, IV and VII with bis-histamine schiff bases and bis-spinaceamine substituted derivatives 142
Carbonic anhydrase I, II, IV and IX inhibition with a series of 7-amino-3,4-dihydroquinolin-2(1H)-one derivatives 141
Synthesis and carbonic anhydrase inhibitory effects of new N-glycosylsulfonamides incorporating the phenol moiety 140
Biochemical and Structural Insights into Carbonic Anhydrase XII/Fab6A10 Complex 139
3-Aminobenzenesulfonamides incorporating acylthiourea moieties selectively inhibit the tumor-associated carbonic anhydrase isoform IX over the off-target isoforms I, II and IV 137
The production and biochemical characterization of α-carbonic anhydrase from Lactobacillus rhamnosus GG 136
Synthesis, biological evaluation and in silico studies with 4-benzylidene-2-phenyl-5(4H)-imidazolone-based benzenesulfonamides as novel selective carbonic anhydrase IX inhibitors endowed with anticancer activity 136
Phenyl(thio)phosphon(amid)ate Benzenesulfonamides as Potent and Selective Inhibitors of Human Carbonic Anhydrases II and VII Counteract Allodynia in a Mouse Model of Oxaliplatin-Induced Neuropathy 135
Synthesis and biological evaluation of novel 3-(quinolin-4-ylamino)benzenesulfonamidesAQ3 as carbonic anhydrase isoforms I and II inhibitors 133
Activation Studies of the β-Carbonic Anhydrase from the Pathogenic Protozoan Entamoeba histolytica with Amino Acids and Amines 132
STABILITY STUDY IN PLASMA OF NOVEL ESTER-LINKED NSAID - CARBONIC ANHYDRASE INHIBITOR HYBRIDS 131
Evaluation of sulphonamide derivatives acting as inhibitors of human carbonic anhydrase isoforms I, II and Mycobacterium tuberculosis β-class enzyme Rv3273 130
Vanillin enones as selective inhibitors of the cancer associated carbonic anhydrase isoforms IX and XII. The out of the active site pocket for the design of selective inhibitors? 129
Inhibition studies on a panel of human carbonic anhydrases with N1-substituted secondary sulfonamides incorporating thiazolinone or imidazolone-indole tails 129
Iodoquinazolinones bearing benzenesulfonamide as human carbonic anhydrase I, II, IX and XII inhibitors: Synthesis, biological evaluation and radiosensitizing activity 128
Discovery of benzenesulfonamide derivatives as carbonic anhydrase inhibitors with effective anticonvulsant action: Design, synthesis, and pharmacological evaluation 128
Benzyl alcohol inhibits carbonic anhydrases by anchoring to the zinc coordinated water molecule 126
Benzenesulfonamides incorporating nitrogenous bases show effective inhibition of β-carbonic anhydrases from the pathogenic fungi Cryptococcus neoformans, Candida glabrata and Malassezia globosa 125
Investigation of carbonic anhydrase inhibitory effects and cytotoxicities of pyrazole-based hybrids carrying hydrazone and zinc-binding benzenesulfonamide pharmacophores 125
Carbonic anhydrase inhibitors as diuretics 125
The effect of substituted benzene-sulfonamides and clinically licensed drugs on the catalytic activity of cynt2, a carbonic anhydrase crucial for escherichia coli life cycle 125
Synthesis and biological evaluation of benzenesulphonamide-bearing 1,4,5-trisubstituted-1,2,3-triazoles possessing human carbonic anhydrase I, II, IV, and IX inhibitory activity 124
Sulphonamide inhibition profile of Staphylococcus aureus β-carbonic anhydrase 124
Mono- and di-thiocarbamate inhibition studies of the δ-carbonic anhydrase TweCAδ from the marine diatom Thalassiosira weissflogii 124
Improving the carbonic anhydrase inhibition profile of the sulfamoylphenyl pharmacophore by attachment of carbohydrate moieties 123
Novel synthesized SLC-0111 thiazole and thiadiazole analogues: Determination of their carbonic anhydrase inhibitory activity and molecular modeling studies 122
Synthesis and selective inhibitory effects of some 2-oxindole benzenesulfonamide conjugates on human carbonic anhydrase isoforms CA I, CA II, CA IX and CAXII 122
The three-tails approach as a new strategy to improve selectivity of action of sulphonamide inhibitors against tumour-associated carbonic anhydrase IX and XII 122
Design, synthesis, and carbonic anhydrase inhibition activity of benzenesulfonamide-linked novel pyrazoline derivatives 120
Benzothiadiazinone-1,1-Dioxide Carbonic Anhydrase Inhibitors Suppress the Growth of Drug-Resistant Mycobacterium tuberculosis Strains 118
Ninhydrins inhibit carbonic anhydrases directly binding to the metal ion 118
Discovery of novel 1,3-diaryltriazene sulfonamides as carbonic anhydrase I, II, VII, and IX inhibitors 116
Indole-Based Hydrazones Containing A Sulfonamide Moiety as Selective Inhibitors of Tumor-Associated Human Carbonic Anhydrase Isoforms IX and XII 116
Natural Polyphenols Selectively Inhibit β-Carbonic Anhydrase from the Dandruff-Producing Fungus Malassezia globosa: Activity and Modeling Studies 116
Discovery of new ureido benzenesulfonamides incorporating 1,3,5-triazine moieties as carbonic anhydrase I, II, IX and XII inhibitors 115
Novel hydrazido benzenesulfonamides-isatin conjugates: Synthesis, carbonic anhydrase inhibitory activity and molecular modeling studies 113
Hypoxia-activated prodrug derivatives of carbonic anhydrase inhibitors in benzenesulfonamide series: Synthesis and biological evaluation 113
Comprehensive study on potent and selective carbonic anhydrase inhibitors: Synthesis, bioactivities and molecular modelling studies of 4-(3-(2-arylidenehydrazine-1-carbonyl)-5-(thiophen-2-yl)-1H-pyrazole-1-yl) benzenesulfonamides 112
Sulfonamide Inhibition Studies of a New β-Carbonic Anhydrase from the Pathogenic Protozoan Entamoeba histolytica 111
S-substituted 2-mercaptoquinazolin-4(3H)-one and 4-ethylbenzensulfonamides act as potent and selective human carbonic anhydrase IX and XII inhibitors 111
Pyrrolo and pyrrolopyrimidine sulfonamides act as cytotoxic agents in hypoxia via inhibition of transmembrane carbonic anhydrases 109
Comparison of the Anion Inhibition Profiles of the α-CA Isoforms (SpiCA1, SpiCA2 and SpiCA3) from the Scleractinian Coral Stylophora pistillata 109
Discovery of potent nucleotide pyrophosphatase/phosphodiesterase3 (NPP3) inhibitors with ancillary carbonic anhydrase inhibition for cancer (immuno)therapy 108
Exploring of tumor-associated carbonic anhydrase isoenzyme IX and XII inhibitory effects and cytotoxicities of the novel N-aryl-1-(4-sulfamoylphenyl)-5-(thiophen-2-yl)-1H-pyrazole-3-carboxamides 108
Synthesis, X-ray structure, in silico calculation, and carbonic anhydrase inhibitory properties of benzylimidazole metal complexes 107
Synthesis and biological evaluation of novel N,N'-diaryl cyanoguanidines acting as potent and selective carbonic anhydrase II inhibitors 106
Insights into the effect of elaborating coumarin-based aryl enaminones with sulfonamide or carboxylic acid functionality on carbonic anhydrase inhibitory potency and selectivity 106
Novel 8-Substituted Coumarins That Selectively Inhibit Human Carbonic Anhydrase IX and XII 106
Carbonic Anhydrase XII Inhibitors Overcome Temozolomide Resistance in Glioblastoma 105
Design and synthesis of novel 1,3-diaryltriazene-substituted sulfonamides as potent and selective carbonic anhydrase II inhibitors 104
Synthesis of novel benzenesulfonamide bearing 1,2,3-triazole linked hydroxy-trifluoromethylpyrazolines and hydrazones as selective carbonic anhydrase isoforms IX and XII inhibitors 102
Novel 2-substituted-benzimidazole-6-sulfonamides as carbonic anhydrase inhibitors: synthesis, biological evaluation against isoforms I, II, IX and XII and molecular docking studies 102
Diagnostic markers for glaucoma: a patent and literature review (2013-2019) 101
Zeta-carbonic anhydrases show CS2 hydrolase activity: A new metabolic carbon acquisition pathway in diatoms? 101
Design, synthesis, and carbonic anhydrase inhibition activities of Schiff bases incorporating benzenesulfonamide scaffold: Molecular docking application 100
Discovery of Potent Carbonic Anhydrase Inhibitors as Effective Anticonvulsant Agents: Drug Design, Synthesis, and in Vitro and in Vivo Investigations 100
Design and synthesis of novel benzenesulfonamide containing 1,2,3-triazoles as potent human carbonic anhydrase isoforms I, II, IV and IX inhibitors 99
Extending the inhibition profiles of coumarin-based compounds against human carbonic anhydrases: Synthesis, biological, and in silico evaluation 99
Design, synthesis and biological evaluation of novel ureido benzenesulfonamides incorporating 1,3,5-triazine moieties as potent carbonic anhydrase IX inhibitors 95
Synthesis of some N-aroyl-2-oxindole benzenesulfonamide conjugates with carbonic anhydrase inhibitory activity 95
Synthesis and comparative carbonic anhydrase inhibition of new Schiff's bases incorporating benzenesulfonamide, methanesulfonamide, and methylsulfonylbenzene scaffolds 95
Click-tailed benzenesulfonamides as potent bacterial carbonic anhydrase inhibitors for targeting Mycobacterium tuberculosis and Vibrio cholerae 93
Synthesis and human/bacterial carbonic anhydrase inhibition with a series of sulfonamides incorporating phthalimido moieties 90
Synthesis of novel benzenesulfamide derivatives with inhibitory activity against human cytosolic carbonic anhydrase I and II and Vibrio cholerae α- and β-class enzymes 90
New anthranilic acid-incorporating N-benzenesulfonamidophthalimides as potent inhibitors of carbonic anhydrases I, II, IX, and XII: Synthesis, in vitro testing, and in silico assessment 89
α-Carbonic anhydrases are strongly activated by spinaceamine derivatives 86
Totale 13.745
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Categoria #
all - tutte 44.005
article - articoli 0
book - libri 0
conference - conferenze 0
curatela - curatele 0
other - altro 0
patent - brevetti 0
selected - selezionate 0
volume - volumi 0
Totale 44.005
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Totale Lug Ago Sett Ott Nov Dic Gen Feb Mar Apr Mag Giu
2021/2022356 0 8 31 27 14 16 8 27 54 34 37 100
2022/2023940 102 208 49 29 55 162 118 48 62 53 26 28
2023/2024688 30 40 109 17 75 94 9 188 20 67 27 12
2024/20254.363 156 447 216 529 1.237 772 57 171 166 113 192 307
2025/20265.893 575 901 943 713 477 185 618 271 330 295 132 453
2026/2027283 172 111 0 0 0 0 0 0 0 0 0 0
Totale 14.062