GUALTIERI, FULVIO
 Distribuzione geografica
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Continente #
NA - Nord America 11.025
EU - Europa 9.982
AS - Asia 4.448
SA - Sud America 531
AF - Africa 133
OC - Oceania 113
Continente sconosciuto - Info sul continente non disponibili 2
Totale 26.234
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Nazione #
US - Stati Uniti d'America 10.931
PL - Polonia 3.497
RU - Federazione Russa 2.440
SG - Singapore 1.278
CN - Cina 1.033
SE - Svezia 848
HK - Hong Kong 796
IT - Italia 762
IE - Irlanda 727
KR - Corea 545
UA - Ucraina 529
BR - Brasile 455
DE - Germania 415
VN - Vietnam 335
FI - Finlandia 304
GB - Regno Unito 221
IN - India 185
AU - Australia 111
FR - Francia 100
TR - Turchia 48
CA - Canada 44
NL - Olanda 42
CI - Costa d'Avorio 40
ID - Indonesia 38
JO - Giordania 33
MX - Messico 32
SC - Seychelles 29
BD - Bangladesh 28
AR - Argentina 27
JP - Giappone 26
IQ - Iraq 24
PK - Pakistan 17
ES - Italia 16
ZA - Sudafrica 16
MA - Marocco 15
EC - Ecuador 12
AT - Austria 11
BE - Belgio 9
CH - Svizzera 9
CO - Colombia 9
CZ - Repubblica Ceca 9
PY - Paraguay 9
RO - Romania 9
CL - Cile 8
UZ - Uzbekistan 8
EG - Egitto 7
JM - Giamaica 7
BJ - Benin 6
LT - Lituania 6
SA - Arabia Saudita 6
VE - Venezuela 6
AM - Armenia 5
AZ - Azerbaigian 5
HR - Croazia 5
HU - Ungheria 5
KE - Kenya 5
BG - Bulgaria 4
IL - Israele 4
AE - Emirati Arabi Uniti 3
CR - Costa Rica 3
IR - Iran 3
LB - Libano 3
LK - Sri Lanka 3
MU - Mauritius 3
PH - Filippine 3
PS - Palestinian Territory 3
PT - Portogallo 3
SK - Slovacchia (Repubblica Slovacca) 3
TN - Tunisia 3
AL - Albania 2
AO - Angola 2
BH - Bahrain 2
DZ - Algeria 2
HN - Honduras 2
KW - Kuwait 2
KZ - Kazakistan 2
NI - Nicaragua 2
NZ - Nuova Zelanda 2
OM - Oman 2
PE - Perù 2
SN - Senegal 2
TT - Trinidad e Tobago 2
UY - Uruguay 2
AF - Afghanistan, Repubblica islamica di 1
BA - Bosnia-Erzegovina 1
BY - Bielorussia 1
DO - Repubblica Dominicana 1
ET - Etiopia 1
EU - Europa 1
GA - Gabon 1
GY - Guiana 1
IS - Islanda 1
KG - Kirghizistan 1
KH - Cambogia 1
LA - Repubblica Popolare Democratica del Laos 1
LU - Lussemburgo 1
LV - Lettonia 1
MD - Moldavia 1
MN - Mongolia 1
NG - Nigeria 1
Totale 26.229
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Città #
Warsaw 3.488
Santa Clara 2.036
Ashburn 1.162
Chandler 825
Singapore 811
Fairfield 779
Jacksonville 741
Dublin 727
Hong Kong 638
Seoul 480
Woodbridge 391
Seattle 350
Cambridge 335
Wilmington 311
Houston 295
Hefei 288
Buffalo 273
Beijing 236
Dong Ket 233
Los Angeles 226
Princeton 184
Boston 143
Mumbai 136
Ann Arbor 134
Boardman 115
The Dalles 115
Melbourne 110
Altamura 105
Council Bluffs 83
Medford 81
Munich 77
San Jose 77
Dallas 76
Lawrence 73
Milan 72
Moscow 71
Seongnam 58
Helsinki 57
Kent 53
Paris 52
Washington 51
New York 48
San Diego 48
Turku 47
Philadelphia 46
Florence 42
Phoenix 42
Abidjan 40
Shanghai 40
Ho Chi Minh City 36
Norwalk 33
São Paulo 32
Frankfurt Am Main 30
West Jordan 30
Falls Church 27
Izmir 27
Jakarta 27
Guangzhou 25
Redondo Beach 25
Tokyo 24
Hanoi 23
Verona 23
Hillsboro 19
Yubileyny 19
Toronto 18
Frankfurt am Main 17
London 17
Andover 16
Baghdad 16
Bengaluru 15
Tianjin 15
Amsterdam 14
Lappeenranta 14
Montreal 14
Salerno 13
San Francisco 12
Brooklyn 11
Chicago 11
Rome 11
Auburn Hills 10
Cedar Knolls 10
Rio de Janeiro 10
Brussels 9
Clifton 9
Dearborn 9
Naples 9
Casablanca 8
Dhaka 8
Johannesburg 8
Ottawa 8
Atlanta 7
Biên Hòa 7
Brasília 7
Charlotte 7
Curitiba 7
Mcallen 7
Poplar 7
Stockholm 7
Treviglio 7
Vienna 7
Totale 17.683
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Nome #
DM235 (sunifiram): a novel nootropic with potential as a cognitive enhancer 541
Antinociceptive property of the nicotinic agonist AG4 in rodents 501
Molecular simplification of 1,4-diazabicyclo[4.3.0]nonan-9-ones gives piperazine derivatives that maintain high nootropic activity 370
4-Aminopiperidine derivatives as a new class of potent cognition enhancing drugs 369
The novel nootropic compound DM232 (UNIFIRAM) ameliorates memory impairment in mice and rats 362
AG-4:A NICOTINIC AGONIST ENDOWED WITH ANTIAMNESIC PROPERTIES 357
3-ALFA-TROPANYL 2-(4-Cl-PHENOXY)BUTIRATE (SM21): A REVIEW OF THE PHARMACOLOGICAL PROFILE OF A NOVEL ENHANCER OF CHOLINERGIC TRANSMISSION. 337
S(-)ET126: a potent and selective M1 antagonist in vitro and in vivo 336
Antisense knockdowns of M1 receptors induces transient anterograde amnesia in mice 309
Antinociceptive profile of SM21: a novel analgesic with a presynaptic cholinergic mechanism of action 305
The functions and structure of ABC transporters: implications for the design of new inhibitors of Pgp and MRP1 to control multidrug resistance (MDR) 301
Central cholinergic antinociception induced by 5HT4 agonists: BIMU 1 and BIMU 8 298
Pharmacological characterization of DM232 (unifiram) and DM235 (sunifiram), new potent cognition-enhancers 294
Central muscarinic antinociception induced by ET-142 and SS-20 in rodents 289
IMPROVEMENT OF COGNITIVE FUNCTIONS BY THE ACETYLCHOLINE RELEASER SM21 287
PHARMACOLOGICAL CHARACTERIZATION OF THE NOVEL ACH RELEASER A-TROPANYL 2-(4-BROMOPHENYL)PROPIONATE (PG-9). 279
Presynaptic Cholinergic Modulators as Potent Cognition Enhancers and Analgesic Drugs. 2. 2-Phenoxy-, 2-(phenylthio)- and 2-(phenylamino)alkanoic Acid Esters 272
Design, synthesis and preliminary pharmacological evaluation of 1,4-diazabicyclo[4.3.0]nonan-9-ones as a new class of highly potent nootropic drugs. 272
Memory facilitation with atropine: a paradoxical effect 271
ANTINOCICEPTIVE EFFECT OF R-(+)-HYOSCYAMMINE ON THE CONJUNCTIVAL REFLEX TEST IN RABBITS 269
Antinociceptive and antiamnesic properties of the presynaptic amplifier PG-9 266
In vitro characterization of a novel, potent and selective M3 antagonist 261
DESIGN, SYNTHESIS AND PRELIMINARY PHARMACOLOGICAL EVALUATION OF RIGID ANALOGUES OF THE NICOTINIC AGONIST 1,1-DIMETHYL-4-PHENYLPIPERAZINIUM IODIDE (DMPP) 259
1,2 BENZISOXAZOLES 256
ANTINOCICEPTION INDUCED BY SM32 DEPENDS ON CENTRAL CHOLINERGIC MECHANISM 255
THE FROZEN ANALOG APPROACH IN MEDICINAL CHEMISTRY 254
Memory facilitation and stimulation of endogenous nerve growth factor synthesis by the ACh releaser PG9 236
Are the contractions of rabbit peripheral lung, guinea-pig gall-bladder and guinea-pig uterus mediated by identical receptor subtype? 226
Binding Profiles of a Series of 2-Arylpropionic Acid Esters on Cloned Human Muscarinic Receptors Subtypes (m1-m5) and Their Relationship to Nootropic Activity 220
1,3-oxathiolane muscarinic ligands modified at the cationic head. 213
(1,3-Dioxolane)- and (1,3-oxathiolane)-2-pyrrolidines: molecular hybrids with potential anti-Alzheimer activity 201
13C NMR SPECTRA OF 1,3-OXATHIOLANE, 1,3-OXATHIOLANE-3-OXIDE AND 1,3-OXATHIOLANE-3,3-DIOXIDE DERIVATIVES 200
2-PYRROLIDINONE MOIETY IS NOT CRITICAL FOR THE COGNITION ENHANCING ACTIVITY OF PIRACETAM-LIKE DRUGS 195
ISOMERIC N,N-BIS(CYCLOHEXANOL)AMINE ARYL ESTERS: THE DISCOVERY OF A NEW CLASS OF HIGHLY POTENT P-GLYCOPROTEIN (PGP)-DEPENDENT MULTIDRUG RESISTANCE (MDR) INHIBITORS 190
SEMI-RIGID ANALOGUES OF THE CALCIUM ANTAGONIST VERAPAMIL: A MOLECULAR MODELLING STUDY 187
Central Nicotinic receptors: structure, function, ligands, and therapeutic potential 187
Highly chiral muscarinic ligands: the discovery of (2S,2'R,3'S,5'R)-1-methyl-2-(2-methyl-1,3-oxathiolan-5-yl)pyrrolidine 3-sulfoxide methyl iodide, a potent, functionally selective, M2 partial agonist. 186
1,4-Diazabicyclo[4.3.0]nonan-9-ones and 1,4-diamidopiperazines as new classes of highly potent nootropic drugs 185
AMPA-receptor activation is involved in the antiamnesic effect of DM 232 (unifiram) and DM 235 (sunifiram). 183
S-(-)-ET126: a potent and selective M1 antagonist 182
ANALGESIC, ANTIMUSCARINIC ACTIVITY AND ENANTIOSELECTIVITY OF THE FOUR ISOMERS OF 3-QUINUCLIDINYL TROPATE AS COMPARED WITH THE ENANTIOMERS OF HYOSCYAMINE 176
Synthesis and Enantioselectivity of the Enantiomers of PG9 and SM21, New Potent Analgesic and Cognition-Enhancing Drugs 174
COGNITION-ENHANCING DRUGS IN MILD COGNITIVE IMPAIRMENT (MCI) AND ALZHEIMER'S DISEASE (AD): AN UPDATE[1] 173
Chiral synthesis and pharmacological evaluation of the enantiomers of SM32, a new analgesic and cognition-enhancing agent. 170
N,N-bis(alkanol)amine aryl esters and N,N-bis(cyclohexanol)amine aryl esters: Idantification of a new class of Pgp-dependent multidrug resistance (MDR) reverters andowed with potencies in the nanomolar range 169
A short synthesis of rigid 2-alkylthio-2,2-diaryl substituted acetic acids 168
1,4-Diazabicyclo[4.3.0]nonan-9-ones as a new class of highly potent nootropic drugs 167
SAR STUDIES ON THE POTENT AND SELECTIVE MUSCARINIC ANTAGONIST 2-ETHYLTHIO-2,2-DIPHENYLACETIC ACID N,N-DIETHYLAMINOETHYL ESTER 166
Synthesis and Cholinergic Affinity of Diastereomeric and Enantiomeric Isomers of 1-Methyl-2-(2-methyl-1,3-dioxolan-4-yl)-pyrrolidine, 1-Methyl-2-(2-methyl-1,3-oxathiolan-5-yl)pyrrolidine and of Their Iodomethylates 166
PRESYNAPTIC AUTO- AND HETERO-RECEPTORS IN THE CHOLINERGIC REGULATION OF PAIN 164
SYNTHESIS AND BIOLOGICAL ACTIVITY OF A SERIES OF ARYL TROPANYL ESTERS AND AMIDES CHEMICALLY RELATED TO 1H-INDOLE-3-CARBOXYLIC ACID ENDO 8-METHYL-8-AZABICYCLO[3.2.1]OCT-3-YL ESTER 164
R-(+)-HYOSCYAMINE: A PERIPHERAL CHOLINERGIC AMPLIFER 163
Structure-affinity relationships of a unique nicotinic ligand: N1-dimethyl-N4-phenylpiperazinium iodide (DMPP) 162
Design, synthesis and pharmacological evaluation of some frozen-analogues of DMPP 161
DIFFERENTIAL ANALGESIC ACTIVITY OF THE ENANTIOMERS OF ATROPINE DERIVATIVES DOES NOT CORRELATE WITH THEIR MUSCARINIC SUBTYPE SELECTIVITY 161
"Synthesis and binding properties of photoactivable Biotin-conjugated verapamil derivatives for the study of P-170 glycoprotein" 158
VERAPAMIL ANALOGUES WITH RESTRICTED MOLECULAR FLEXIBILITY: SYNTHESIS AND PHARMACOLOGICAL EVALUATION OF THE FOUR ISOMERS OF ALPHA-[1-[3-[N-[1-[2-(3,4-DIMETHOXYPHENYL)ETHYL]]-N-METHYLAMINO]CYCLOHEXYL]]-ALPHA-ISOPROPYL-3,4-DIMETHOXYBENZENEACETONITRILE 156
ANTIAMNESIC ACTIVITY OF METOCLOPRAMIDE, CISAPRIDE AND SR-17 IN THE MOUSE PASSIVE AVOIDANCE TEST 154
A SEARCH FOR CALCIUM CHANNELS ACTIVATORS IN THE VERAPAMIL SERIES 154
Affinity and efficacy correlate with chemical structure more than potency does in a series of pentatomic cyclic muscarinic agonists 154
MOLECULAR MODULATION OF MUSCARINIC ANTAGONISTS. SYNTHESIS AND PHARMACOLOGICAL PROFILE OF 2,2-DIPHENYL-2-ETHYLTHIOACETIC AND 3,3-DIPHENYL-3-ETHYLTHIOPROPIONIC ACID DERIVATIVES CHARACTERIZED BY A DIPEPTIDE SPACER 153
REDUCED FLEXIBILITY ANALOGS OF ANALGESIC AND COGNITION-ENHANCING A-TROPANYL ESTERS 150
STRUCTURAL DEPENDENCE OF THE ALLOSTERIC INTERACTION OF SEMI-RIGID VERAPAMIL ANALOGUES WITH DIHYDROPYRIDINE-BINDING IN KITTEN HEART 149
Design, synthesis and preliminary pharmacological evaluation of new analogues of DM232 (unifiram) and DM235 (sunifiram) as cognition modulators 149
25 Years later: latest news from the receptors 146
Presynaptic Cholinergic Modulators as Potent Cognition Enhancers and Analgesic Drugs. 1. Tropic and 2-Phenylpropionic Acid Esters 146
The medicinal chemistry of multidrug resistance (MDR) reversing drugs 146
CHOLINERGIC RECEPTORS AND NEURODEGENERATIVE DISEASES 143
Exploratory chemistry toward the identification of a new class of MDR reverters inspired by pervilleine and verapamil models 143
SYNTHESIS AND PHARMACOLOGICAL EVALUATION OF VERAPAMIL ANALOGS WITH RESTRICTED MOLECULAR FLEXIBILITY 142
Muscarinic subtype affinity and functional activity profile of 1-methyl-2-(2-methyl-1,3-dioxolan-4-yl)pyrrolidine and 1-methyl-2-(2-methyl-1,3-oxathiolan-5-yl)pyrrolidine derivatives. 142
A DIRECT METALLATION APPROACH TO 2-ALKYLTHIO-2,2-DIARYL SUBSTITUTED ACETIC ACIDS 141
Attività analgesica e antimuscarinica ed enantioselettività dei quattro isomeri del tropato del 3-chinuclidinolo messe a confronto con gli enantiomeri della iosciamina 140
The novel nootropic drugs DM232 (Unifiram) and DM235 (Sunifiram) ameliorate memory impairment in mice and rats 139
Enantioselective synthesis and preliminary pharmacological evaluation of the enantiomers of unifiram (DM232), a potent cognition-enhancing agent 138
Design, synthesis and preliminary pharmacological evaluation of 4-aminopiperidine derivatives as N-type calcium channel blockers active on pain and neuropathic pain 138
Alpha-tropanyl esters that increase central ACh release: enantioselectivity studies support a double mechanism of action. 138
Structure-activity relationships in 2,2-diphenyl-2-ethylthioacetic acid esters: unexpected agonistic activity in a series of muscarinic antagonists. 137
Effect of 5-HT4 agonists metoclopramide and Compound 1 on learning and memory 137
The quest for the treatment of cognitive impairment: alpha 7 nicotinic and alpha 5 GABA-A receptor modulators 136
Design, synthesis and preliminary pharmacological evaluation of a set of small molecules that directly activate Gi proteins. 135
CHIRALITY OF DRUG RECEPTOR INTERACTIONS: A SOURCE OF VALUABLE INFORMATION 134
NEGATIVE INOTROPIC ACTIVITY OF PARA-SUBSTITUTED DIETHYL BENZYL PHOSPHONATES RELATED TO FOSTEDIL 134
RECENT ADVANCES IN RECEPTOR CHEMISTRY 133
DISEGNO E SINTESI DI FARMACI E MEZZI DI INDAGINE FARMACOLOGICA 132
A recombinant transductor-effector system: in vitro study of G inhibitor protein (G-alfa-i1)direct activators 132
MUSCARINIC PRESYNAPTIC AUTORECEPTORS AND MUSCARINIC POSTSYNAPTIC RECEPTORS HAVE OPPOSITE STEREOCHEMICAL REQUIREMENTS 131
Differential analgesic activity of the enantiomers of atropine derivatives does not correlate with their muscarinic subtype selectivity 131
Synthesis of Hexahydro-[2]pyrindine(=Hexahydrocyclopenta[c]pyridine) Derivatives as Conformationally Restricted Analogs of the Nicotinic Ligands Arecolone and Isoarecolone 131
Analoghi a ridotta flessibilità molecolare di nuovi farmaci ad azione nootropa ed analgesica 131
Design and study of piracetam-like nootropics, controversial members of the problematic class of cognition-enhancing drugs 128
DIALKYLAMINOALKYL ESTERS OF 2,2-DIPHENYL-2-ALKYLTIOACETIC ACIDS: A NEW CLASS OF POTENT AND FUNCTIONALLY SELECTIVE MUSCARINIC ANTAGONISTS 127
AFFINITY PROFILES AT FIVE CLONED HUMAN MUSCARINIC RECEPTORS (M1-M5) OF A NEW SERIES OF ANTIMUSCARINIC DRUGS 124
NEGATIVE INOTROPIC AND CALCIUM ANTAGONISTIC ACTIVITY OF ALKYL AND ARYLALKYL PHOSPHONATES 123
Design, synthesis and preliminary pharmacological evaluation of 1,4-diaminobenzenes and 1,4-diaminocyclohexanes as cognition modulators 122
DM232 and DM235, two potent cognition-enhancers, increase NO levels in rat adipocytes 122
Highly chiral muscarinic ligands: synthesis and affinity of diastereomeric and enantiomeric isomers of 1-methyl-2-(2-methyl-1,3-oxathiolane-5-yl)pyrrolidine 3-sulfoxides and their methyl iodides 119
N,N-DIETHYLAMINOETHANOL AND N-METHYL-4-PIPERIDINOL ESTERS OF 2,2-DIPHENYL-2-ETHYLTHIOACETIC ACID AS POTENT AND SELECTIVE MUSCARINIC ANTAGONISTS 117
ORGANIC SYNTHESIS AND MEDICINAL CHEMISTRY 117
VERAPAMIL ANALOGUES WITH RESTRICTED MOLECULAR FLEXIBILITY 116
Totale 19.633
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Categoria #
all - tutte 64.446
article - articoli 0
book - libri 0
conference - conferenze 0
curatela - curatele 0
other - altro 0
patent - brevetti 0
selected - selezionate 0
volume - volumi 0
Totale 64.446
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Totale Lug Ago Sett Ott Nov Dic Gen Feb Mar Apr Mag Giu
2020/20211.284 0 0 0 0 0 0 88 230 170 323 101 372
2021/20221.180 32 176 55 52 42 39 37 74 38 33 271 331
2022/20232.899 290 352 104 279 281 582 363 204 289 17 99 39
2023/20241.629 54 133 241 79 104 340 46 471 25 43 38 55
2024/20256.698 279 771 445 945 1.819 823 97 424 351 208 287 249
2025/20264.554 920 1.186 859 416 743 347 83 0 0 0 0 0
Totale 26.355