GUALTIERI, FULVIO
 Distribuzione geografica
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Continente #
NA - Nord America 13.096
EU - Europa 11.267
AS - Asia 5.540
SA - Sud America 607
AF - Africa 168
Continente sconosciuto - Info sul continente non disponibili 124
OC - Oceania 113
Totale 30.915
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Nazione #
US - Stati Uniti d'America 12.842
PL - Polonia 3.503
RU - Federazione Russa 2.440
IT - Italia 1.773
SG - Singapore 1.546
CN - Cina 1.307
SE - Svezia 851
HK - Hong Kong 812
IE - Irlanda 728
VN - Vietnam 693
KR - Corea 548
UA - Ucraina 529
BR - Brasile 492
DE - Germania 438
FI - Finlandia 348
FR - Francia 255
GB - Regno Unito 238
IN - India 201
CA - Canada 153
AU - Australia 111
JP - Giappone 107
TR - Turchia 55
NL - Olanda 47
BD - Bangladesh 46
MX - Messico 42
CI - Costa d'Avorio 41
ID - Indonesia 40
AR - Argentina 38
JO - Giordania 36
IQ - Iraq 29
SC - Seychelles 29
PK - Pakistan 24
ES - Italia 23
ZA - Sudafrica 22
NG - Nigeria 19
CO - Colombia 18
MA - Marocco 17
CL - Cile 15
EC - Ecuador 15
JM - Giamaica 13
AT - Austria 12
VE - Venezuela 12
BE - Belgio 10
CH - Svizzera 10
CZ - Repubblica Ceca 10
RO - Romania 10
UZ - Uzbekistan 10
EG - Egitto 9
PY - Paraguay 9
AZ - Azerbaigian 8
SA - Arabia Saudita 8
TT - Trinidad e Tobago 8
LT - Lituania 7
TH - Thailandia 7
BJ - Benin 6
CR - Costa Rica 6
KE - Kenya 6
MY - Malesia 6
PH - Filippine 6
PR - Porto Rico 6
AM - Armenia 5
HR - Croazia 5
HU - Ungheria 5
LB - Libano 5
NP - Nepal 5
TN - Tunisia 5
AE - Emirati Arabi Uniti 4
AL - Albania 4
BG - Bulgaria 4
HN - Honduras 4
IL - Israele 4
NI - Nicaragua 4
UY - Uruguay 4
BH - Bahrain 3
DZ - Algeria 3
GT - Guatemala 3
IR - Iran 3
KZ - Kazakistan 3
LK - Sri Lanka 3
MU - Mauritius 3
OM - Oman 3
PA - Panama 3
PS - Palestinian Territory 3
PT - Portogallo 3
SK - Slovacchia (Repubblica Slovacca) 3
SN - Senegal 3
AO - Angola 2
BA - Bosnia-Erzegovina 2
BB - Barbados 2
BS - Bahamas 2
DO - Repubblica Dominicana 2
ET - Etiopia 2
GP - Guadalupe 2
KG - Kirghizistan 2
KW - Kuwait 2
MD - Moldavia 2
NZ - Nuova Zelanda 2
PE - Perù 2
AF - Afghanistan, Repubblica islamica di 1
BY - Bielorussia 1
Totale 30.773
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Città #
Warsaw 3.492
Santa Clara 2.088
Ashburn 1.520
Singapore 1.068
Chandler 825
Fairfield 780
Jacksonville 743
Dublin 727
Hong Kong 650
San Jose 492
Seoul 480
Woodbridge 392
Milan 372
Seattle 358
Council Bluffs 342
Cambridge 337
Wilmington 311
Houston 298
Hefei 288
Buffalo 278
Beijing 250
Los Angeles 243
Dong Ket 233
The Dalles 201
Princeton 185
Lauterbourg 146
Boston 144
Ho Chi Minh City 137
Mumbai 137
Ann Arbor 135
Boardman 121
Hanoi 120
Rome 119
Melbourne 110
Altamura 105
Tokyo 105
Helsinki 101
Phoenix 92
Dallas 86
Medford 81
Munich 77
Lawrence 74
New York 72
Moscow 71
Florence 59
Seongnam 58
Kent 54
Paris 54
San Diego 52
Washington 52
Philadelphia 50
Naples 48
Turku 47
Shanghai 46
Abidjan 41
Columbus 41
São Paulo 38
Bologna 35
Guangzhou 34
Norwalk 34
Chicago 32
Turin 32
Frankfurt Am Main 30
Frankfurt am Main 30
Verona 30
West Jordan 30
Figino 29
Izmir 28
Orem 28
Falls Church 27
Jakarta 27
Montreal 25
Redondo Beach 25
Palermo 24
Hillsboro 23
Toronto 23
London 22
Bari 21
Brooklyn 21
Da Nang 21
Yubileyny 19
Abuja 18
Baghdad 18
San Francisco 18
Venice 18
Haiphong 17
Tianjin 17
Amsterdam 16
Andover 16
Bengaluru 16
Salerno 15
Lappeenranta 14
Genoa 13
Biên Hòa 12
Brescia 12
Mexico City 12
Springfield 12
Atlanta 11
Las Vegas 11
Rio de Janeiro 11
Totale 20.553
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Nome #
DM235 (sunifiram): a novel nootropic with potential as a cognitive enhancer 705
Antinociceptive property of the nicotinic agonist AG4 in rodents 535
Molecular simplification of 1,4-diazabicyclo[4.3.0]nonan-9-ones gives piperazine derivatives that maintain high nootropic activity 432
The novel nootropic compound DM232 (UNIFIRAM) ameliorates memory impairment in mice and rats 423
4-Aminopiperidine derivatives as a new class of potent cognition enhancing drugs 421
AG-4:A NICOTINIC AGONIST ENDOWED WITH ANTIAMNESIC PROPERTIES 405
3-ALFA-TROPANYL 2-(4-Cl-PHENOXY)BUTIRATE (SM21): A REVIEW OF THE PHARMACOLOGICAL PROFILE OF A NOVEL ENHANCER OF CHOLINERGIC TRANSMISSION. 384
S(-)ET126: a potent and selective M1 antagonist in vitro and in vivo 365
Antinociceptive profile of SM21: a novel analgesic with a presynaptic cholinergic mechanism of action 345
Antisense knockdowns of M1 receptors induces transient anterograde amnesia in mice 341
The functions and structure of ABC transporters: implications for the design of new inhibitors of Pgp and MRP1 to control multidrug resistance (MDR) 336
Central cholinergic antinociception induced by 5HT4 agonists: BIMU 1 and BIMU 8 325
IMPROVEMENT OF COGNITIVE FUNCTIONS BY THE ACETYLCHOLINE RELEASER SM21 320
Central muscarinic antinociception induced by ET-142 and SS-20 in rodents 319
Pharmacological characterization of DM232 (unifiram) and DM235 (sunifiram), new potent cognition-enhancers 318
Design, synthesis and preliminary pharmacological evaluation of 1,4-diazabicyclo[4.3.0]nonan-9-ones as a new class of highly potent nootropic drugs. 313
PHARMACOLOGICAL CHARACTERIZATION OF THE NOVEL ACH RELEASER A-TROPANYL 2-(4-BROMOPHENYL)PROPIONATE (PG-9). 311
Antinociceptive and antiamnesic properties of the presynaptic amplifier PG-9 306
Presynaptic Cholinergic Modulators as Potent Cognition Enhancers and Analgesic Drugs. 2. 2-Phenoxy-, 2-(phenylthio)- and 2-(phenylamino)alkanoic Acid Esters 305
Memory facilitation with atropine: a paradoxical effect 305
ANTINOCICEPTIVE EFFECT OF R-(+)-HYOSCYAMMINE ON THE CONJUNCTIVAL REFLEX TEST IN RABBITS 299
DESIGN, SYNTHESIS AND PRELIMINARY PHARMACOLOGICAL EVALUATION OF RIGID ANALOGUES OF THE NICOTINIC AGONIST 1,1-DIMETHYL-4-PHENYLPIPERAZINIUM IODIDE (DMPP) 298
In vitro characterization of a novel, potent and selective M3 antagonist 294
ANTINOCICEPTION INDUCED BY SM32 DEPENDS ON CENTRAL CHOLINERGIC MECHANISM 290
1,2 BENZISOXAZOLES 274
Memory facilitation and stimulation of endogenous nerve growth factor synthesis by the ACh releaser PG9 269
THE FROZEN ANALOG APPROACH IN MEDICINAL CHEMISTRY 267
1,3-oxathiolane muscarinic ligands modified at the cationic head. 262
Are the contractions of rabbit peripheral lung, guinea-pig gall-bladder and guinea-pig uterus mediated by identical receptor subtype? 251
Binding Profiles of a Series of 2-Arylpropionic Acid Esters on Cloned Human Muscarinic Receptors Subtypes (m1-m5) and Their Relationship to Nootropic Activity 249
(1,3-Dioxolane)- and (1,3-oxathiolane)-2-pyrrolidines: molecular hybrids with potential anti-Alzheimer activity 236
13C NMR SPECTRA OF 1,3-OXATHIOLANE, 1,3-OXATHIOLANE-3-OXIDE AND 1,3-OXATHIOLANE-3,3-DIOXIDE DERIVATIVES 226
Central Nicotinic receptors: structure, function, ligands, and therapeutic potential 220
AMPA-receptor activation is involved in the antiamnesic effect of DM 232 (unifiram) and DM 235 (sunifiram). 218
1,4-Diazabicyclo[4.3.0]nonan-9-ones and 1,4-diamidopiperazines as new classes of highly potent nootropic drugs 218
2-PYRROLIDINONE MOIETY IS NOT CRITICAL FOR THE COGNITION ENHANCING ACTIVITY OF PIRACETAM-LIKE DRUGS 217
SEMI-RIGID ANALOGUES OF THE CALCIUM ANTAGONIST VERAPAMIL: A MOLECULAR MODELLING STUDY 212
ISOMERIC N,N-BIS(CYCLOHEXANOL)AMINE ARYL ESTERS: THE DISCOVERY OF A NEW CLASS OF HIGHLY POTENT P-GLYCOPROTEIN (PGP)-DEPENDENT MULTIDRUG RESISTANCE (MDR) INHIBITORS 210
COGNITION-ENHANCING DRUGS IN MILD COGNITIVE IMPAIRMENT (MCI) AND ALZHEIMER'S DISEASE (AD): AN UPDATE[1] 210
Highly chiral muscarinic ligands: the discovery of (2S,2'R,3'S,5'R)-1-methyl-2-(2-methyl-1,3-oxathiolan-5-yl)pyrrolidine 3-sulfoxide methyl iodide, a potent, functionally selective, M2 partial agonist. 209
S-(-)-ET126: a potent and selective M1 antagonist 203
ANALGESIC, ANTIMUSCARINIC ACTIVITY AND ENANTIOSELECTIVITY OF THE FOUR ISOMERS OF 3-QUINUCLIDINYL TROPATE AS COMPARED WITH THE ENANTIOMERS OF HYOSCYAMINE 200
Synthesis and Enantioselectivity of the Enantiomers of PG9 and SM21, New Potent Analgesic and Cognition-Enhancing Drugs 195
A short synthesis of rigid 2-alkylthio-2,2-diaryl substituted acetic acids 193
Synthesis and Cholinergic Affinity of Diastereomeric and Enantiomeric Isomers of 1-Methyl-2-(2-methyl-1,3-dioxolan-4-yl)-pyrrolidine, 1-Methyl-2-(2-methyl-1,3-oxathiolan-5-yl)pyrrolidine and of Their Iodomethylates 193
R-(+)-HYOSCYAMINE: A PERIPHERAL CHOLINERGIC AMPLIFER 192
1,4-Diazabicyclo[4.3.0]nonan-9-ones as a new class of highly potent nootropic drugs 192
Design, synthesis and pharmacological evaluation of some frozen-analogues of DMPP 190
N,N-bis(alkanol)amine aryl esters and N,N-bis(cyclohexanol)amine aryl esters: Idantification of a new class of Pgp-dependent multidrug resistance (MDR) reverters andowed with potencies in the nanomolar range 189
SYNTHESIS AND BIOLOGICAL ACTIVITY OF A SERIES OF ARYL TROPANYL ESTERS AND AMIDES CHEMICALLY RELATED TO 1H-INDOLE-3-CARBOXYLIC ACID ENDO 8-METHYL-8-AZABICYCLO[3.2.1]OCT-3-YL ESTER 186
Structure-affinity relationships of a unique nicotinic ligand: N1-dimethyl-N4-phenylpiperazinium iodide (DMPP) 186
The medicinal chemistry of multidrug resistance (MDR) reversing drugs 185
"Synthesis and binding properties of photoactivable Biotin-conjugated verapamil derivatives for the study of P-170 glycoprotein" 183
Chiral synthesis and pharmacological evaluation of the enantiomers of SM32, a new analgesic and cognition-enhancing agent. 182
SAR STUDIES ON THE POTENT AND SELECTIVE MUSCARINIC ANTAGONIST 2-ETHYLTHIO-2,2-DIPHENYLACETIC ACID N,N-DIETHYLAMINOETHYL ESTER 178
PRESYNAPTIC AUTO- AND HETERO-RECEPTORS IN THE CHOLINERGIC REGULATION OF PAIN 177
Affinity and efficacy correlate with chemical structure more than potency does in a series of pentatomic cyclic muscarinic agonists 177
The novel nootropic drugs DM232 (Unifiram) and DM235 (Sunifiram) ameliorate memory impairment in mice and rats 177
Attività analgesica e antimuscarinica ed enantioselettività dei quattro isomeri del tropato del 3-chinuclidinolo messe a confronto con gli enantiomeri della iosciamina 177
DIFFERENTIAL ANALGESIC ACTIVITY OF THE ENANTIOMERS OF ATROPINE DERIVATIVES DOES NOT CORRELATE WITH THEIR MUSCARINIC SUBTYPE SELECTIVITY 177
MOLECULAR MODULATION OF MUSCARINIC ANTAGONISTS. SYNTHESIS AND PHARMACOLOGICAL PROFILE OF 2,2-DIPHENYL-2-ETHYLTHIOACETIC AND 3,3-DIPHENYL-3-ETHYLTHIOPROPIONIC ACID DERIVATIVES CHARACTERIZED BY A DIPEPTIDE SPACER 176
VERAPAMIL ANALOGUES WITH RESTRICTED MOLECULAR FLEXIBILITY: SYNTHESIS AND PHARMACOLOGICAL EVALUATION OF THE FOUR ISOMERS OF ALPHA-[1-[3-[N-[1-[2-(3,4-DIMETHOXYPHENYL)ETHYL]]-N-METHYLAMINO]CYCLOHEXYL]]-ALPHA-ISOPROPYL-3,4-DIMETHOXYBENZENEACETONITRILE 174
Design, synthesis and preliminary pharmacological evaluation of new analogues of DM232 (unifiram) and DM235 (sunifiram) as cognition modulators 174
ANTIAMNESIC ACTIVITY OF METOCLOPRAMIDE, CISAPRIDE AND SR-17 IN THE MOUSE PASSIVE AVOIDANCE TEST 173
A SEARCH FOR CALCIUM CHANNELS ACTIVATORS IN THE VERAPAMIL SERIES 173
STRUCTURAL DEPENDENCE OF THE ALLOSTERIC INTERACTION OF SEMI-RIGID VERAPAMIL ANALOGUES WITH DIHYDROPYRIDINE-BINDING IN KITTEN HEART 169
SYNTHESIS AND PHARMACOLOGICAL EVALUATION OF VERAPAMIL ANALOGS WITH RESTRICTED MOLECULAR FLEXIBILITY 169
Presynaptic Cholinergic Modulators as Potent Cognition Enhancers and Analgesic Drugs. 1. Tropic and 2-Phenylpropionic Acid Esters 167
Enantioselective synthesis and preliminary pharmacological evaluation of the enantiomers of unifiram (DM232), a potent cognition-enhancing agent 167
Exploratory chemistry toward the identification of a new class of MDR reverters inspired by pervilleine and verapamil models 167
Muscarinic subtype affinity and functional activity profile of 1-methyl-2-(2-methyl-1,3-dioxolan-4-yl)pyrrolidine and 1-methyl-2-(2-methyl-1,3-oxathiolan-5-yl)pyrrolidine derivatives. 166
REDUCED FLEXIBILITY ANALOGS OF ANALGESIC AND COGNITION-ENHANCING A-TROPANYL ESTERS 165
Analoghi a ridotta flessibilità molecolare di nuovi farmaci ad azione nootropa ed analgesica 165
Alpha-tropanyl esters that increase central ACh release: enantioselectivity studies support a double mechanism of action. 164
25 Years later: latest news from the receptors 163
Synthesis of Hexahydro-[2]pyrindine(=Hexahydrocyclopenta[c]pyridine) Derivatives as Conformationally Restricted Analogs of the Nicotinic Ligands Arecolone and Isoarecolone 163
A DIRECT METALLATION APPROACH TO 2-ALKYLTHIO-2,2-DIARYL SUBSTITUTED ACETIC ACIDS 159
CHOLINERGIC RECEPTORS AND NEURODEGENERATIVE DISEASES 159
A recombinant transductor-effector system: in vitro study of G inhibitor protein (G-alfa-i1)direct activators 159
Design, synthesis and preliminary pharmacological evaluation of 4-aminopiperidine derivatives as N-type calcium channel blockers active on pain and neuropathic pain 159
The quest for the treatment of cognitive impairment: alpha 7 nicotinic and alpha 5 GABA-A receptor modulators 157
Design, synthesis and preliminary pharmacological evaluation of a set of small molecules that directly activate Gi proteins. 157
Effect of 5-HT4 agonists metoclopramide and Compound 1 on learning and memory 156
DISEGNO E SINTESI DI FARMACI E MEZZI DI INDAGINE FARMACOLOGICA 155
Structure-activity relationships in 2,2-diphenyl-2-ethylthioacetic acid esters: unexpected agonistic activity in a series of muscarinic antagonists. 155
Differential analgesic activity of the enantiomers of atropine derivatives does not correlate with their muscarinic subtype selectivity 155
Design, synthesis and preliminary pharmacological evaluation of 1,4-diaminobenzenes and 1,4-diaminocyclohexanes as cognition modulators 151
RECENT ADVANCES IN RECEPTOR CHEMISTRY 151
DIALKYLAMINOALKYL ESTERS OF 2,2-DIPHENYL-2-ALKYLTIOACETIC ACIDS: A NEW CLASS OF POTENT AND FUNCTIONALLY SELECTIVE MUSCARINIC ANTAGONISTS 151
Design and study of piracetam-like nootropics, controversial members of the problematic class of cognition-enhancing drugs 149
DM232 and DM235, two potent cognition-enhancers, increase NO levels in rat adipocytes 148
AFFINITY PROFILES AT FIVE CLONED HUMAN MUSCARINIC RECEPTORS (M1-M5) OF A NEW SERIES OF ANTIMUSCARINIC DRUGS 147
NEGATIVE INOTROPIC ACTIVITY OF PARA-SUBSTITUTED DIETHYL BENZYL PHOSPHONATES RELATED TO FOSTEDIL 147
CHIRALITY OF DRUG RECEPTOR INTERACTIONS: A SOURCE OF VALUABLE INFORMATION 145
VERAPAMIL ANALOGUES WITH RESTRICTED MOLECULAR FLEXIBILITY 141
MUSCARINIC PRESYNAPTIC AUTORECEPTORS AND MUSCARINIC POSTSYNAPTIC RECEPTORS HAVE OPPOSITE STEREOCHEMICAL REQUIREMENTS 140
Antinociceptive and antiamnesic properties of the nicotinic agonist AG-4 140
Highly chiral muscarinic ligands: synthesis and affinity of diastereomeric and enantiomeric isomers of 1-methyl-2-(2-methyl-1,3-oxathiolane-5-yl)pyrrolidine 3-sulfoxides and their methyl iodides 140
SAR studies in a series of N,N-bis(arylaLKANOL)AMINE ARYL ESTERS AS p-GLYCOPROTEIN (Pgp) dependent multidrug resistance (MDR) inhibitors 138
4-(2-Pyrrolidinyl)-1,3-dioxolane derivatives as ligands for muscarinic and nicotinic receptors 138
Totale 22.467
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Categoria #
all - tutte 77.660
article - articoli 0
book - libri 0
conference - conferenze 0
curatela - curatele 0
other - altro 0
patent - brevetti 0
selected - selezionate 0
volume - volumi 0
Totale 77.660
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Totale Lug Ago Sett Ott Nov Dic Gen Feb Mar Apr Mag Giu
2021/2022972 0 0 55 52 42 39 37 74 38 33 271 331
2022/20232.899 290 352 104 279 281 582 363 204 289 17 99 39
2023/20241.629 54 133 241 79 104 340 46 471 25 43 38 55
2024/20256.698 279 771 445 945 1.819 823 97 424 351 208 287 249
2025/20267.946 920 1.186 859 416 743 347 897 359 519 447 196 1.057
2026/20271.168 282 335 551 0 0 0 0 0 0 0 0 0
Totale 30.915