GUALTIERI, FULVIO
 Distribuzione geografica
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Continente #
NA - Nord America 8.837
EU - Europa 8.819
AS - Asia 1.454
AF - Africa 74
SA - Sud America 3
Continente sconosciuto - Info sul continente non disponibili 1
OC - Oceania 1
Totale 19.189
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Nazione #
US - Stati Uniti d'America 8.817
PL - Polonia 3.485
RU - Federazione Russa 1.736
SE - Svezia 842
IE - Irlanda 727
IT - Italia 621
UA - Ucraina 520
HK - Hong Kong 378
DE - Germania 338
SG - Singapore 317
FI - Finlandia 249
VN - Vietnam 239
CN - Cina 227
GB - Regno Unito 187
IN - India 140
KR - Corea 70
FR - Francia 46
CI - Costa d'Avorio 39
SC - Seychelles 29
TR - Turchia 29
JO - Giordania 27
NL - Olanda 21
CA - Canada 18
JP - Giappone 14
BE - Belgio 9
RO - Romania 8
CH - Svizzera 7
AT - Austria 5
HR - Croazia 5
ES - Italia 4
CZ - Repubblica Ceca 3
AM - Armenia 2
DZ - Algeria 2
IR - Iran 2
MU - Mauritius 2
MX - Messico 2
AF - Afghanistan, Repubblica islamica di 1
AR - Argentina 1
BG - Bulgaria 1
CL - Cile 1
EC - Ecuador 1
EU - Europa 1
HU - Ungheria 1
IL - Israele 1
KE - Kenya 1
KH - Cambogia 1
LB - Libano 1
LK - Sri Lanka 1
LU - Lussemburgo 1
LV - Lettonia 1
MD - Moldavia 1
NG - Nigeria 1
NZ - Nuova Zelanda 1
PH - Filippine 1
SK - Slovacchia (Repubblica Slovacca) 1
TH - Thailandia 1
TW - Taiwan 1
UZ - Uzbekistan 1
Totale 19.189
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Città #
Warsaw 3.480
Santa Clara 1.369
Ashburn 862
Chandler 825
Fairfield 779
Jacksonville 739
Dublin 727
Woodbridge 391
Seattle 348
Cambridge 335
Wilmington 311
Houston 289
Dong Ket 233
Hong Kong 221
Singapore 217
Princeton 184
Boston 138
Ann Arbor 134
Mumbai 129
Boardman 115
Altamura 105
Buffalo 81
Medford 81
Beijing 76
Lawrence 73
Seongnam 58
Milan 56
Washington 51
Helsinki 50
San Diego 48
Philadelphia 46
Abidjan 39
Shanghai 38
Florence 34
Norwalk 33
Los Angeles 32
Phoenix 32
Frankfurt Am Main 30
Moscow 30
West Jordan 30
Falls Church 27
Izmir 27
Kent 23
New York 22
Guangzhou 21
Verona 21
Munich 20
Hillsboro 19
Yubileyny 19
Andover 16
Lappeenranta 14
Tokyo 12
Salerno 11
Auburn Hills 10
Cedar Knolls 10
Toronto 10
Brussels 9
Dearborn 9
London 7
Mcallen 7
Ottawa 7
Treviglio 7
Bern 6
Hanover 6
Kochi 5
Moncalieri 5
Napoli 5
Romola 5
Seoul 5
Tappahannock 5
Frankfurt am Main 4
Giugliano In Campania 4
Palermo 4
Piscataway 4
Sesto Fiorentino 4
Vienna 4
Barcelona 3
Central 3
Chicago 3
Düsseldorf 3
Groningen 3
Kilburn 3
Laurel 3
Monza 3
Naaldwijk 3
Pozzuoli 3
San Martino Buon Albergo 3
Sassano 3
Trumbull 3
Turate 3
Venice 3
Wroclaw 3
Arezzo 2
Aversa 2
Bengaluru 2
Bitonto 2
Bolzano 2
Bremen 2
Brindisi 2
Buccinasco 2
Totale 13.307
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Nome #
Antinociceptive property of the nicotinic agonist AG4 in rodents 458
DM235 (sunifiram): a novel nootropic with potential as a cognitive enhancer 363
Molecular simplification of 1,4-diazabicyclo[4.3.0]nonan-9-ones gives piperazine derivatives that maintain high nootropic activity 302
The novel nootropic compound DM232 (UNIFIRAM) ameliorates memory impairment in mice and rats 293
4-Aminopiperidine derivatives as a new class of potent cognition enhancing drugs 287
AG-4:A NICOTINIC AGONIST ENDOWED WITH ANTIAMNESIC PROPERTIES 283
S(-)ET126: a potent and selective M1 antagonist in vitro and in vivo 263
Antisense knockdowns of M1 receptors induces transient anterograde amnesia in mice 262
3-ALFA-TROPANYL 2-(4-Cl-PHENOXY)BUTIRATE (SM21): A REVIEW OF THE PHARMACOLOGICAL PROFILE OF A NOVEL ENHANCER OF CHOLINERGIC TRANSMISSION. 257
The functions and structure of ABC transporters: implications for the design of new inhibitors of Pgp and MRP1 to control multidrug resistance (MDR) 257
Pharmacological characterization of DM232 (unifiram) and DM235 (sunifiram), new potent cognition-enhancers 252
Central cholinergic antinociception induced by 5HT4 agonists: BIMU 1 and BIMU 8 250
Central muscarinic antinociception induced by ET-142 and SS-20 in rodents 247
Memory facilitation with atropine: a paradoxical effect 246
IMPROVEMENT OF COGNITIVE FUNCTIONS BY THE ACETYLCHOLINE RELEASER SM21 242
Antinociceptive profile of SM21: a novel analgesic with a presynaptic cholinergic mechanism of action 242
PHARMACOLOGICAL CHARACTERIZATION OF THE NOVEL ACH RELEASER A-TROPANYL 2-(4-BROMOPHENYL)PROPIONATE (PG-9). 240
Presynaptic Cholinergic Modulators as Potent Cognition Enhancers and Analgesic Drugs. 2. 2-Phenoxy-, 2-(phenylthio)- and 2-(phenylamino)alkanoic Acid Esters 237
In vitro characterization of a novel, potent and selective M3 antagonist 234
ANTINOCICEPTIVE EFFECT OF R-(+)-HYOSCYAMMINE ON THE CONJUNCTIVAL REFLEX TEST IN RABBITS 231
Design, synthesis and preliminary pharmacological evaluation of 1,4-diazabicyclo[4.3.0]nonan-9-ones as a new class of highly potent nootropic drugs. 223
ANTINOCICEPTION INDUCED BY SM32 DEPENDS ON CENTRAL CHOLINERGIC MECHANISM 221
Are the contractions of rabbit peripheral lung, guinea-pig gall-bladder and guinea-pig uterus mediated by identical receptor subtype? 208
Antinociceptive and antiamnesic properties of the presynaptic amplifier PG-9 207
Memory facilitation and stimulation of endogenous nerve growth factor synthesis by the ACh releaser PG9 206
DESIGN, SYNTHESIS AND PRELIMINARY PHARMACOLOGICAL EVALUATION OF RIGID ANALOGUES OF THE NICOTINIC AGONIST 1,1-DIMETHYL-4-PHENYLPIPERAZINIUM IODIDE (DMPP) 201
Binding Profiles of a Series of 2-Arylpropionic Acid Esters on Cloned Human Muscarinic Receptors Subtypes (m1-m5) and Their Relationship to Nootropic Activity 199
THE FROZEN ANALOG APPROACH IN MEDICINAL CHEMISTRY 193
1,2 BENZISOXAZOLES 171
1,3-oxathiolane muscarinic ligands modified at the cationic head. 143
Highly chiral muscarinic ligands: the discovery of (2S,2'R,3'S,5'R)-1-methyl-2-(2-methyl-1,3-oxathiolan-5-yl)pyrrolidine 3-sulfoxide methyl iodide, a potent, functionally selective, M2 partial agonist. 141
ISOMERIC N,N-BIS(CYCLOHEXANOL)AMINE ARYL ESTERS: THE DISCOVERY OF A NEW CLASS OF HIGHLY POTENT P-GLYCOPROTEIN (PGP)-DEPENDENT MULTIDRUG RESISTANCE (MDR) INHIBITORS 138
Synthesis and Cholinergic Affinity of Diastereomeric and Enantiomeric Isomers of 1-Methyl-2-(2-methyl-1,3-dioxolan-4-yl)-pyrrolidine, 1-Methyl-2-(2-methyl-1,3-oxathiolan-5-yl)pyrrolidine and of Their Iodomethylates 137
(1,3-Dioxolane)- and (1,3-oxathiolane)-2-pyrrolidines: molecular hybrids with potential anti-Alzheimer activity 136
Central Nicotinic receptors: structure, function, ligands, and therapeutic potential 134
Structure-affinity relationships of a unique nicotinic ligand: N1-dimethyl-N4-phenylpiperazinium iodide (DMPP) 132
Chiral synthesis and pharmacological evaluation of the enantiomers of SM32, a new analgesic and cognition-enhancing agent. 132
13C NMR SPECTRA OF 1,3-OXATHIOLANE, 1,3-OXATHIOLANE-3-OXIDE AND 1,3-OXATHIOLANE-3,3-DIOXIDE DERIVATIVES 131
2-PYRROLIDINONE MOIETY IS NOT CRITICAL FOR THE COGNITION ENHANCING ACTIVITY OF PIRACETAM-LIKE DRUGS 131
Synthesis and Enantioselectivity of the Enantiomers of PG9 and SM21, New Potent Analgesic and Cognition-Enhancing Drugs 128
COGNITION-ENHANCING DRUGS IN MILD COGNITIVE IMPAIRMENT (MCI) AND ALZHEIMER'S DISEASE (AD): AN UPDATE[1] 125
The medicinal chemistry of multidrug resistance (MDR) reversing drugs 122
PRESYNAPTIC AUTO- AND HETERO-RECEPTORS IN THE CHOLINERGIC REGULATION OF PAIN 121
Presynaptic Cholinergic Modulators as Potent Cognition Enhancers and Analgesic Drugs. 1. Tropic and 2-Phenylpropionic Acid Esters 120
DIFFERENTIAL ANALGESIC ACTIVITY OF THE ENANTIOMERS OF ATROPINE DERIVATIVES DOES NOT CORRELATE WITH THEIR MUSCARINIC SUBTYPE SELECTIVITY 120
SAR STUDIES ON THE POTENT AND SELECTIVE MUSCARINIC ANTAGONIST 2-ETHYLTHIO-2,2-DIPHENYLACETIC ACID N,N-DIETHYLAMINOETHYL ESTER 119
AMPA-receptor activation is involved in the antiamnesic effect of DM 232 (unifiram) and DM 235 (sunifiram). 119
1,4-Diazabicyclo[4.3.0]nonan-9-ones and 1,4-diamidopiperazines as new classes of highly potent nootropic drugs 119
CHOLINERGIC RECEPTORS AND NEURODEGENERATIVE DISEASES 118
1,4-Diazabicyclo[4.3.0]nonan-9-ones as a new class of highly potent nootropic drugs 117
SEMI-RIGID ANALOGUES OF THE CALCIUM ANTAGONIST VERAPAMIL: A MOLECULAR MODELLING STUDY 116
S-(-)-ET126: a potent and selective M1 antagonist 115
"Synthesis and binding properties of photoactivable Biotin-conjugated verapamil derivatives for the study of P-170 glycoprotein" 115
Muscarinic subtype affinity and functional activity profile of 1-methyl-2-(2-methyl-1,3-dioxolan-4-yl)pyrrolidine and 1-methyl-2-(2-methyl-1,3-oxathiolan-5-yl)pyrrolidine derivatives. 113
The novel nootropic drugs DM232 (Unifiram) and DM235 (Sunifiram) ameliorate memory impairment in mice and rats 112
ANTIAMNESIC ACTIVITY OF METOCLOPRAMIDE, CISAPRIDE AND SR-17 IN THE MOUSE PASSIVE AVOIDANCE TEST 111
Affinity and efficacy correlate with chemical structure more than potency does in a series of pentatomic cyclic muscarinic agonists 111
Synthesis of Hexahydro-[2]pyrindine(=Hexahydrocyclopenta[c]pyridine) Derivatives as Conformationally Restricted Analogs of the Nicotinic Ligands Arecolone and Isoarecolone 111
Enantioselective synthesis and preliminary pharmacological evaluation of the enantiomers of unifiram (DM232), a potent cognition-enhancing agent 111
A short synthesis of rigid 2-alkylthio-2,2-diaryl substituted acetic acids 110
Design, synthesis and preliminary pharmacological evaluation of a set of small molecules that directly activate Gi proteins. 109
VERAPAMIL ANALOGUES WITH RESTRICTED MOLECULAR FLEXIBILITY: SYNTHESIS AND PHARMACOLOGICAL EVALUATION OF THE FOUR ISOMERS OF ALPHA-[1-[3-[N-[1-[2-(3,4-DIMETHOXYPHENYL)ETHYL]]-N-METHYLAMINO]CYCLOHEXYL]]-ALPHA-ISOPROPYL-3,4-DIMETHOXYBENZENEACETONITRILE 108
RECENT ADVANCES IN RECEPTOR CHEMISTRY 108
The quest for the treatment of cognitive impairment: alpha 7 nicotinic and alpha 5 GABA-A receptor modulators 107
REDUCED FLEXIBILITY ANALOGS OF ANALGESIC AND COGNITION-ENHANCING A-TROPANYL ESTERS 106
MOLECULAR MODULATION OF MUSCARINIC ANTAGONISTS. SYNTHESIS AND PHARMACOLOGICAL PROFILE OF 2,2-DIPHENYL-2-ETHYLTHIOACETIC AND 3,3-DIPHENYL-3-ETHYLTHIOPROPIONIC ACID DERIVATIVES CHARACTERIZED BY A DIPEPTIDE SPACER 105
NEGATIVE INOTROPIC ACTIVITY OF PARA-SUBSTITUTED DIETHYL BENZYL PHOSPHONATES RELATED TO FOSTEDIL 105
ANALGESIC, ANTIMUSCARINIC ACTIVITY AND ENANTIOSELECTIVITY OF THE FOUR ISOMERS OF 3-QUINUCLIDINYL TROPATE AS COMPARED WITH THE ENANTIOMERS OF HYOSCYAMINE 104
STRUCTURAL DEPENDENCE OF THE ALLOSTERIC INTERACTION OF SEMI-RIGID VERAPAMIL ANALOGUES WITH DIHYDROPYRIDINE-BINDING IN KITTEN HEART 104
Structure-activity relationships in 2,2-diphenyl-2-ethylthioacetic acid esters: unexpected agonistic activity in a series of muscarinic antagonists. 104
Design, synthesis and preliminary pharmacological evaluation of new analogues of DM232 (unifiram) and DM235 (sunifiram) as cognition modulators 104
Effect of 5-HT4 agonists metoclopramide and Compound 1 on learning and memory 103
Design, synthesis and preliminary pharmacological evaluation of 4-aminopiperidine derivatives as N-type calcium channel blockers active on pain and neuropathic pain 103
Design and study of piracetam-like nootropics, controversial members of the problematic class of cognition-enhancing drugs 101
CHIRALITY OF DRUG RECEPTOR INTERACTIONS: A SOURCE OF VALUABLE INFORMATION 100
Design, synthesis and pharmacological evaluation of some frozen-analogues of DMPP 99
N,N-bis(alkanol)amine aryl esters and N,N-bis(cyclohexanol)amine aryl esters: Idantification of a new class of Pgp-dependent multidrug resistance (MDR) reverters andowed with potencies in the nanomolar range 97
SYNTHESIS AND BIOLOGICAL ACTIVITY OF A SERIES OF ARYL TROPANYL ESTERS AND AMIDES CHEMICALLY RELATED TO 1H-INDOLE-3-CARBOXYLIC ACID ENDO 8-METHYL-8-AZABICYCLO[3.2.1]OCT-3-YL ESTER 96
25 Years later: latest news from the receptors 96
Attività analgesica e antimuscarinica ed enantioselettività dei quattro isomeri del tropato del 3-chinuclidinolo messe a confronto con gli enantiomeri della iosciamina 95
Differential analgesic activity of the enantiomers of atropine derivatives does not correlate with their muscarinic subtype selectivity 95
EUDISMIC ANALYSIS OF A SERIES OF MUSCARINIC LIGANDS CARRYING A 1,3-OXATHIOLANE NUCLEUS 94
SYNTHESIS AND PHARMACOLOGICAL EVALUATION OF VERAPAMIL ANALOGS WITH RESTRICTED MOLECULAR FLEXIBILITY 92
A DIRECT METALLATION APPROACH TO 2-ALKYLTHIO-2,2-DIARYL SUBSTITUTED ACETIC ACIDS 92
MUSCARINIC PRESYNAPTIC AUTORECEPTORS AND MUSCARINIC POSTSYNAPTIC RECEPTORS HAVE OPPOSITE STEREOCHEMICAL REQUIREMENTS 92
Reversal of multidrug resistance by verapamil analogues 92
R-(+)-HYOSCYAMINE: A PERIPHERAL CHOLINERGIC AMPLIFER 91
A SEARCH FOR CALCIUM CHANNELS ACTIVATORS IN THE VERAPAMIL SERIES 90
Chiral muscarinic agonists possessing a 1,3-oxathiolane nucleus: enantio- and tissue-selectivity on isolated preparations of guinea-pig ileum and atria and of rat urinary bladder 90
Exploratory chemistry toward the identification of a new class of MDR reverters inspired by pervilleine and verapamil models 90
DISEGNO E SINTESI DI FARMACI E MEZZI DI INDAGINE FARMACOLOGICA 89
DIALKYLAMINOALKYL ESTERS OF 2,2-DIPHENYL-2-ALKYLTIOACETIC ACIDS: A NEW CLASS OF POTENT AND FUNCTIONALLY SELECTIVE MUSCARINIC ANTAGONISTS 89
ORGANIC SYNTHESIS AND MEDICINAL CHEMISTRY 86
Enantioselectivity of muscarinic antagonists. Isomeric 2-Cyclohexyl-2-phenyl-5-((dimethylamino)methyl)-1,3-oxathiolane 3-Oxide Methiodides 85
Analoghi a ridotta flessibilità molecolare di nuovi farmaci ad azione nootropa ed analgesica 84
A recombinant transductor-effector system: in vitro study of G inhibitor protein (G-alfa-i1)direct activators 83
NEGATIVE INOTROPIC AND CALCIUM ANTAGONISTIC ACTIVITY OF ALKYL AND ARYLALKYL PHOSPHONATES 80
AFFINITY PROFILES AT FIVE CLONED HUMAN MUSCARINIC RECEPTORS (M1-M5) OF A NEW SERIES OF ANTIMUSCARINIC DRUGS 78
N,N-DIETHYLAMINOETHANOL AND N-METHYL-4-PIPERIDINOL ESTERS OF 2,2-DIPHENYL-2-ETHYLTHIOACETIC ACID AS POTENT AND SELECTIVE MUSCARINIC ANTAGONISTS 77
VERAPAMIL ANALOGUES WITH RESTRICTED MOLECULAR FLEXIBILITY 76
Totale 14.882
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Categoria #
all - tutte 45.414
article - articoli 0
book - libri 0
conference - conferenze 0
curatela - curatele 0
other - altro 0
patent - brevetti 0
selected - selezionate 0
volume - volumi 0
Totale 45.414
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Totale Lug Ago Sett Ott Nov Dic Gen Feb Mar Apr Mag Giu
2019/20201.926 0 0 0 0 289 330 221 380 207 148 303 48
2020/20212.480 170 158 181 254 80 353 88 230 170 323 101 372
2021/20221.180 32 176 55 52 42 39 37 74 38 33 271 331
2022/20232.899 290 352 104 279 281 582 363 204 289 17 99 39
2023/20241.629 54 133 241 79 104 340 46 471 25 43 38 55
2024/20254.207 279 771 445 945 1.767 0 0 0 0 0 0 0
Totale 19.310