GUALTIERI, FULVIO
 Distribuzione geografica
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Continente #
NA - Nord America 12.065
EU - Europa 11.197
AS - Asia 5.524
SA - Sud America 593
AF - Africa 168
OC - Oceania 113
Continente sconosciuto - Info sul continente non disponibili 3
Totale 29.663
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Nazione #
US - Stati Uniti d'America 11.928
PL - Polonia 3.503
RU - Federazione Russa 2.440
IT - Italia 1.713
SG - Singapore 1.543
CN - Cina 1.304
SE - Svezia 850
HK - Hong Kong 811
IE - Irlanda 728
VN - Vietnam 691
KR - Corea 548
UA - Ucraina 529
BR - Brasile 487
DE - Germania 435
FI - Finlandia 348
FR - Francia 254
GB - Regno Unito 236
IN - India 201
AU - Australia 111
JP - Giappone 107
CA - Canada 63
TR - Turchia 55
NL - Olanda 47
BD - Bangladesh 46
CI - Costa d'Avorio 41
MX - Messico 41
ID - Indonesia 39
AR - Argentina 37
JO - Giordania 36
IQ - Iraq 29
SC - Seychelles 29
PK - Pakistan 23
ES - Italia 22
ZA - Sudafrica 22
NG - Nigeria 19
CO - Colombia 17
MA - Marocco 17
CL - Cile 15
AT - Austria 12
EC - Ecuador 12
JM - Giamaica 11
CH - Svizzera 10
CZ - Repubblica Ceca 10
RO - Romania 10
UZ - Uzbekistan 10
BE - Belgio 9
EG - Egitto 9
PY - Paraguay 9
AZ - Azerbaigian 8
SA - Arabia Saudita 8
VE - Venezuela 8
LT - Lituania 7
BJ - Benin 6
KE - Kenya 6
TH - Thailandia 6
AM - Armenia 5
CR - Costa Rica 5
HR - Croazia 5
HU - Ungheria 5
LB - Libano 5
NP - Nepal 5
PH - Filippine 5
TN - Tunisia 5
AE - Emirati Arabi Uniti 4
AL - Albania 4
BG - Bulgaria 4
HN - Honduras 4
IL - Israele 4
MY - Malesia 4
UY - Uruguay 4
BH - Bahrain 3
DZ - Algeria 3
IR - Iran 3
KZ - Kazakistan 3
LK - Sri Lanka 3
MU - Mauritius 3
NI - Nicaragua 3
OM - Oman 3
PA - Panama 3
PS - Palestinian Territory 3
PT - Portogallo 3
SK - Slovacchia (Repubblica Slovacca) 3
SN - Senegal 3
AO - Angola 2
BA - Bosnia-Erzegovina 2
DO - Repubblica Dominicana 2
ET - Etiopia 2
KG - Kirghizistan 2
KW - Kuwait 2
MD - Moldavia 2
NZ - Nuova Zelanda 2
PE - Perù 2
PR - Porto Rico 2
TT - Trinidad e Tobago 2
AF - Afghanistan, Repubblica islamica di 1
BS - Bahamas 1
BY - Bielorussia 1
EU - Europa 1
GA - Gabon 1
GF - Guiana Francese 1
Totale 29.651
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Città #
Warsaw 3.492
Santa Clara 2.071
Ashburn 1.433
Singapore 1.065
Chandler 825
Fairfield 780
Jacksonville 743
Dublin 727
Hong Kong 649
Seoul 480
Woodbridge 392
Milan 367
Seattle 352
Cambridge 335
San Jose 319
Wilmington 311
Houston 295
Hefei 288
Buffalo 274
Beijing 250
Los Angeles 236
Dong Ket 233
The Dalles 201
Princeton 185
Council Bluffs 157
Lauterbourg 146
Boston 144
Mumbai 137
Ho Chi Minh City 135
Ann Arbor 134
Boardman 121
Hanoi 120
Melbourne 110
Rome 109
Altamura 105
Tokyo 105
Helsinki 101
Medford 81
Dallas 79
Munich 77
Lawrence 73
Moscow 71
New York 64
Seongnam 58
Florence 56
Paris 54
Kent 53
Washington 52
San Diego 49
Philadelphia 48
Turku 47
Shanghai 46
Phoenix 45
Naples 43
Abidjan 41
São Paulo 38
Bologna 34
Guangzhou 34
Norwalk 33
Frankfurt Am Main 30
Verona 30
West Jordan 30
Frankfurt am Main 29
Figino 28
Izmir 28
Orem 28
Turin 28
Falls Church 27
Jakarta 27
Redondo Beach 25
Palermo 24
Da Nang 21
Hillsboro 21
Bari 19
London 19
Yubileyny 19
Abuja 18
Baghdad 18
Toronto 18
Haiphong 17
Tianjin 17
Venice 17
Amsterdam 16
Andover 16
Bengaluru 16
Brooklyn 15
Montreal 15
San Francisco 15
Chicago 14
Lappeenranta 14
Salerno 14
Biên Hòa 12
Genoa 12
Mexico City 12
Brescia 11
Rio de Janeiro 11
Atlanta 10
Auburn Hills 10
Cedar Knolls 10
Johannesburg 10
Totale 19.874
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Nome #
DM235 (sunifiram): a novel nootropic with potential as a cognitive enhancer 661
Antinociceptive property of the nicotinic agonist AG4 in rodents 526
Molecular simplification of 1,4-diazabicyclo[4.3.0]nonan-9-ones gives piperazine derivatives that maintain high nootropic activity 423
4-Aminopiperidine derivatives as a new class of potent cognition enhancing drugs 408
The novel nootropic compound DM232 (UNIFIRAM) ameliorates memory impairment in mice and rats 407
AG-4:A NICOTINIC AGONIST ENDOWED WITH ANTIAMNESIC PROPERTIES 395
3-ALFA-TROPANYL 2-(4-Cl-PHENOXY)BUTIRATE (SM21): A REVIEW OF THE PHARMACOLOGICAL PROFILE OF A NOVEL ENHANCER OF CHOLINERGIC TRANSMISSION. 375
S(-)ET126: a potent and selective M1 antagonist in vitro and in vivo 359
Antinociceptive profile of SM21: a novel analgesic with a presynaptic cholinergic mechanism of action 339
Antisense knockdowns of M1 receptors induces transient anterograde amnesia in mice 333
The functions and structure of ABC transporters: implications for the design of new inhibitors of Pgp and MRP1 to control multidrug resistance (MDR) 324
Central cholinergic antinociception induced by 5HT4 agonists: BIMU 1 and BIMU 8 320
Central muscarinic antinociception induced by ET-142 and SS-20 in rodents 312
Pharmacological characterization of DM232 (unifiram) and DM235 (sunifiram), new potent cognition-enhancers 310
IMPROVEMENT OF COGNITIVE FUNCTIONS BY THE ACETYLCHOLINE RELEASER SM21 308
Design, synthesis and preliminary pharmacological evaluation of 1,4-diazabicyclo[4.3.0]nonan-9-ones as a new class of highly potent nootropic drugs. 307
PHARMACOLOGICAL CHARACTERIZATION OF THE NOVEL ACH RELEASER A-TROPANYL 2-(4-BROMOPHENYL)PROPIONATE (PG-9). 307
Presynaptic Cholinergic Modulators as Potent Cognition Enhancers and Analgesic Drugs. 2. 2-Phenoxy-, 2-(phenylthio)- and 2-(phenylamino)alkanoic Acid Esters 301
Memory facilitation with atropine: a paradoxical effect 298
Antinociceptive and antiamnesic properties of the presynaptic amplifier PG-9 297
DESIGN, SYNTHESIS AND PRELIMINARY PHARMACOLOGICAL EVALUATION OF RIGID ANALOGUES OF THE NICOTINIC AGONIST 1,1-DIMETHYL-4-PHENYLPIPERAZINIUM IODIDE (DMPP) 292
ANTINOCICEPTIVE EFFECT OF R-(+)-HYOSCYAMMINE ON THE CONJUNCTIVAL REFLEX TEST IN RABBITS 290
In vitro characterization of a novel, potent and selective M3 antagonist 283
ANTINOCICEPTION INDUCED BY SM32 DEPENDS ON CENTRAL CHOLINERGIC MECHANISM 282
1,2 BENZISOXAZOLES 270
THE FROZEN ANALOG APPROACH IN MEDICINAL CHEMISTRY 261
Memory facilitation and stimulation of endogenous nerve growth factor synthesis by the ACh releaser PG9 261
1,3-oxathiolane muscarinic ligands modified at the cationic head. 256
Are the contractions of rabbit peripheral lung, guinea-pig gall-bladder and guinea-pig uterus mediated by identical receptor subtype? 247
Binding Profiles of a Series of 2-Arylpropionic Acid Esters on Cloned Human Muscarinic Receptors Subtypes (m1-m5) and Their Relationship to Nootropic Activity 245
(1,3-Dioxolane)- and (1,3-oxathiolane)-2-pyrrolidines: molecular hybrids with potential anti-Alzheimer activity 226
13C NMR SPECTRA OF 1,3-OXATHIOLANE, 1,3-OXATHIOLANE-3-OXIDE AND 1,3-OXATHIOLANE-3,3-DIOXIDE DERIVATIVES 219
AMPA-receptor activation is involved in the antiamnesic effect of DM 232 (unifiram) and DM 235 (sunifiram). 213
Central Nicotinic receptors: structure, function, ligands, and therapeutic potential 213
1,4-Diazabicyclo[4.3.0]nonan-9-ones and 1,4-diamidopiperazines as new classes of highly potent nootropic drugs 211
2-PYRROLIDINONE MOIETY IS NOT CRITICAL FOR THE COGNITION ENHANCING ACTIVITY OF PIRACETAM-LIKE DRUGS 207
Highly chiral muscarinic ligands: the discovery of (2S,2'R,3'S,5'R)-1-methyl-2-(2-methyl-1,3-oxathiolan-5-yl)pyrrolidine 3-sulfoxide methyl iodide, a potent, functionally selective, M2 partial agonist. 207
SEMI-RIGID ANALOGUES OF THE CALCIUM ANTAGONIST VERAPAMIL: A MOLECULAR MODELLING STUDY 204
COGNITION-ENHANCING DRUGS IN MILD COGNITIVE IMPAIRMENT (MCI) AND ALZHEIMER'S DISEASE (AD): AN UPDATE[1] 203
ISOMERIC N,N-BIS(CYCLOHEXANOL)AMINE ARYL ESTERS: THE DISCOVERY OF A NEW CLASS OF HIGHLY POTENT P-GLYCOPROTEIN (PGP)-DEPENDENT MULTIDRUG RESISTANCE (MDR) INHIBITORS 202
S-(-)-ET126: a potent and selective M1 antagonist 200
ANALGESIC, ANTIMUSCARINIC ACTIVITY AND ENANTIOSELECTIVITY OF THE FOUR ISOMERS OF 3-QUINUCLIDINYL TROPATE AS COMPARED WITH THE ENANTIOMERS OF HYOSCYAMINE 196
Synthesis and Enantioselectivity of the Enantiomers of PG9 and SM21, New Potent Analgesic and Cognition-Enhancing Drugs 190
A short synthesis of rigid 2-alkylthio-2,2-diaryl substituted acetic acids 189
Synthesis and Cholinergic Affinity of Diastereomeric and Enantiomeric Isomers of 1-Methyl-2-(2-methyl-1,3-dioxolan-4-yl)-pyrrolidine, 1-Methyl-2-(2-methyl-1,3-oxathiolan-5-yl)pyrrolidine and of Their Iodomethylates 189
R-(+)-HYOSCYAMINE: A PERIPHERAL CHOLINERGIC AMPLIFER 187
Design, synthesis and pharmacological evaluation of some frozen-analogues of DMPP 185
1,4-Diazabicyclo[4.3.0]nonan-9-ones as a new class of highly potent nootropic drugs 185
Structure-affinity relationships of a unique nicotinic ligand: N1-dimethyl-N4-phenylpiperazinium iodide (DMPP) 181
N,N-bis(alkanol)amine aryl esters and N,N-bis(cyclohexanol)amine aryl esters: Idantification of a new class of Pgp-dependent multidrug resistance (MDR) reverters andowed with potencies in the nanomolar range 181
SYNTHESIS AND BIOLOGICAL ACTIVITY OF A SERIES OF ARYL TROPANYL ESTERS AND AMIDES CHEMICALLY RELATED TO 1H-INDOLE-3-CARBOXYLIC ACID ENDO 8-METHYL-8-AZABICYCLO[3.2.1]OCT-3-YL ESTER 178
Chiral synthesis and pharmacological evaluation of the enantiomers of SM32, a new analgesic and cognition-enhancing agent. 178
The medicinal chemistry of multidrug resistance (MDR) reversing drugs 177
DIFFERENTIAL ANALGESIC ACTIVITY OF THE ENANTIOMERS OF ATROPINE DERIVATIVES DOES NOT CORRELATE WITH THEIR MUSCARINIC SUBTYPE SELECTIVITY 176
"Synthesis and binding properties of photoactivable Biotin-conjugated verapamil derivatives for the study of P-170 glycoprotein" 176
PRESYNAPTIC AUTO- AND HETERO-RECEPTORS IN THE CHOLINERGIC REGULATION OF PAIN 172
SAR STUDIES ON THE POTENT AND SELECTIVE MUSCARINIC ANTAGONIST 2-ETHYLTHIO-2,2-DIPHENYLACETIC ACID N,N-DIETHYLAMINOETHYL ESTER 171
Affinity and efficacy correlate with chemical structure more than potency does in a series of pentatomic cyclic muscarinic agonists 171
Attività analgesica e antimuscarinica ed enantioselettività dei quattro isomeri del tropato del 3-chinuclidinolo messe a confronto con gli enantiomeri della iosciamina 171
Design, synthesis and preliminary pharmacological evaluation of new analogues of DM232 (unifiram) and DM235 (sunifiram) as cognition modulators 170
MOLECULAR MODULATION OF MUSCARINIC ANTAGONISTS. SYNTHESIS AND PHARMACOLOGICAL PROFILE OF 2,2-DIPHENYL-2-ETHYLTHIOACETIC AND 3,3-DIPHENYL-3-ETHYLTHIOPROPIONIC ACID DERIVATIVES CHARACTERIZED BY A DIPEPTIDE SPACER 170
ANTIAMNESIC ACTIVITY OF METOCLOPRAMIDE, CISAPRIDE AND SR-17 IN THE MOUSE PASSIVE AVOIDANCE TEST 168
The novel nootropic drugs DM232 (Unifiram) and DM235 (Sunifiram) ameliorate memory impairment in mice and rats 167
A SEARCH FOR CALCIUM CHANNELS ACTIVATORS IN THE VERAPAMIL SERIES 166
VERAPAMIL ANALOGUES WITH RESTRICTED MOLECULAR FLEXIBILITY: SYNTHESIS AND PHARMACOLOGICAL EVALUATION OF THE FOUR ISOMERS OF ALPHA-[1-[3-[N-[1-[2-(3,4-DIMETHOXYPHENYL)ETHYL]]-N-METHYLAMINO]CYCLOHEXYL]]-ALPHA-ISOPROPYL-3,4-DIMETHOXYBENZENEACETONITRILE 165
STRUCTURAL DEPENDENCE OF THE ALLOSTERIC INTERACTION OF SEMI-RIGID VERAPAMIL ANALOGUES WITH DIHYDROPYRIDINE-BINDING IN KITTEN HEART 163
Presynaptic Cholinergic Modulators as Potent Cognition Enhancers and Analgesic Drugs. 1. Tropic and 2-Phenylpropionic Acid Esters 162
Enantioselective synthesis and preliminary pharmacological evaluation of the enantiomers of unifiram (DM232), a potent cognition-enhancing agent 162
SYNTHESIS AND PHARMACOLOGICAL EVALUATION OF VERAPAMIL ANALOGS WITH RESTRICTED MOLECULAR FLEXIBILITY 161
Exploratory chemistry toward the identification of a new class of MDR reverters inspired by pervilleine and verapamil models 160
Muscarinic subtype affinity and functional activity profile of 1-methyl-2-(2-methyl-1,3-dioxolan-4-yl)pyrrolidine and 1-methyl-2-(2-methyl-1,3-oxathiolan-5-yl)pyrrolidine derivatives. 160
REDUCED FLEXIBILITY ANALOGS OF ANALGESIC AND COGNITION-ENHANCING A-TROPANYL ESTERS 159
Analoghi a ridotta flessibilità molecolare di nuovi farmaci ad azione nootropa ed analgesica 158
25 Years later: latest news from the receptors 157
Synthesis of Hexahydro-[2]pyrindine(=Hexahydrocyclopenta[c]pyridine) Derivatives as Conformationally Restricted Analogs of the Nicotinic Ligands Arecolone and Isoarecolone 156
A recombinant transductor-effector system: in vitro study of G inhibitor protein (G-alfa-i1)direct activators 156
A DIRECT METALLATION APPROACH TO 2-ALKYLTHIO-2,2-DIARYL SUBSTITUTED ACETIC ACIDS 155
CHOLINERGIC RECEPTORS AND NEURODEGENERATIVE DISEASES 155
Effect of 5-HT4 agonists metoclopramide and Compound 1 on learning and memory 155
Design, synthesis and preliminary pharmacological evaluation of 4-aminopiperidine derivatives as N-type calcium channel blockers active on pain and neuropathic pain 155
The quest for the treatment of cognitive impairment: alpha 7 nicotinic and alpha 5 GABA-A receptor modulators 154
Design, synthesis and preliminary pharmacological evaluation of a set of small molecules that directly activate Gi proteins. 154
Alpha-tropanyl esters that increase central ACh release: enantioselectivity studies support a double mechanism of action. 154
Differential analgesic activity of the enantiomers of atropine derivatives does not correlate with their muscarinic subtype selectivity 152
Structure-activity relationships in 2,2-diphenyl-2-ethylthioacetic acid esters: unexpected agonistic activity in a series of muscarinic antagonists. 148
DISEGNO E SINTESI DI FARMACI E MEZZI DI INDAGINE FARMACOLOGICA 146
RECENT ADVANCES IN RECEPTOR CHEMISTRY 145
Design and study of piracetam-like nootropics, controversial members of the problematic class of cognition-enhancing drugs 144
CHIRALITY OF DRUG RECEPTOR INTERACTIONS: A SOURCE OF VALUABLE INFORMATION 143
Design, synthesis and preliminary pharmacological evaluation of 1,4-diaminobenzenes and 1,4-diaminocyclohexanes as cognition modulators 143
DIALKYLAMINOALKYL ESTERS OF 2,2-DIPHENYL-2-ALKYLTIOACETIC ACIDS: A NEW CLASS OF POTENT AND FUNCTIONALLY SELECTIVE MUSCARINIC ANTAGONISTS 143
AFFINITY PROFILES AT FIVE CLONED HUMAN MUSCARINIC RECEPTORS (M1-M5) OF A NEW SERIES OF ANTIMUSCARINIC DRUGS 142
DM232 and DM235, two potent cognition-enhancers, increase NO levels in rat adipocytes 142
NEGATIVE INOTROPIC ACTIVITY OF PARA-SUBSTITUTED DIETHYL BENZYL PHOSPHONATES RELATED TO FOSTEDIL 141
MUSCARINIC PRESYNAPTIC AUTORECEPTORS AND MUSCARINIC POSTSYNAPTIC RECEPTORS HAVE OPPOSITE STEREOCHEMICAL REQUIREMENTS 137
Highly chiral muscarinic ligands: synthesis and affinity of diastereomeric and enantiomeric isomers of 1-methyl-2-(2-methyl-1,3-oxathiolane-5-yl)pyrrolidine 3-sulfoxides and their methyl iodides 135
Antinociceptive and antiamnesic properties of the nicotinic agonist AG-4 134
SAR studies in a series of N,N-bis(arylaLKANOL)AMINE ARYL ESTERS AS p-GLYCOPROTEIN (Pgp) dependent multidrug resistance (MDR) inhibitors 132
4-(2-Pyrrolidinyl)-1,3-dioxolane derivatives as ligands for muscarinic and nicotinic receptors 132
VERAPAMIL ANALOGUES WITH RESTRICTED MOLECULAR FLEXIBILITY 131
Totale 21.787
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Categoria #
all - tutte 73.534
article - articoli 0
book - libri 0
conference - conferenze 0
curatela - curatele 0
other - altro 0
patent - brevetti 0
selected - selezionate 0
volume - volumi 0
Totale 73.534
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Totale Lug Ago Sett Ott Nov Dic Gen Feb Mar Apr Mag Giu
2021/20221.180 32 176 55 52 42 39 37 74 38 33 271 331
2022/20232.899 290 352 104 279 281 582 363 204 289 17 99 39
2023/20241.629 54 133 241 79 104 340 46 471 25 43 38 55
2024/20256.698 279 771 445 945 1.819 823 97 424 351 208 287 249
2025/20267.946 920 1.186 859 416 743 347 897 359 519 447 196 1.057
2026/202737 37 0 0 0 0 0 0 0 0 0 0 0
Totale 29.784