GUALTIERI, FULVIO
 Distribuzione geografica
Continente #
NA - Nord America 7.010
EU - Europa 6.987
AS - Asia 926
AF - Africa 34
SA - Sud America 2
Continente sconosciuto - Info sul continente non disponibili 1
OC - Oceania 1
Totale 14.961
Nazione #
US - Stati Uniti d'America 6.990
PL - Polonia 3.485
SE - Svezia 842
IE - Irlanda 727
IT - Italia 589
UA - Ucraina 520
HK - Hong Kong 373
DE - Germania 322
VN - Vietnam 239
FI - Finlandia 199
GB - Regno Unito 186
CN - Cina 131
KR - Corea 67
FR - Francia 44
SC - Seychelles 29
SG - Singapore 29
TR - Turchia 29
JO - Giordania 27
NL - Olanda 21
CA - Canada 18
JP - Giappone 12
IN - India 11
BE - Belgio 9
RO - Romania 8
CH - Svizzera 7
AT - Austria 5
HR - Croazia 5
RU - Federazione Russa 5
ES - Italia 4
CZ - Repubblica Ceca 3
DZ - Algeria 2
IR - Iran 2
MU - Mauritius 2
MX - Messico 2
AF - Afghanistan, Repubblica islamica di 1
AM - Armenia 1
BG - Bulgaria 1
CL - Cile 1
EC - Ecuador 1
EU - Europa 1
HU - Ungheria 1
KE - Kenya 1
KH - Cambogia 1
LB - Libano 1
LU - Lussemburgo 1
LV - Lettonia 1
MD - Moldavia 1
NZ - Nuova Zelanda 1
PH - Filippine 1
SK - Slovacchia (Repubblica Slovacca) 1
UZ - Uzbekistan 1
Totale 14.961
Città #
Warsaw 3.480
Ashburn 845
Chandler 825
Fairfield 779
Jacksonville 739
Dublin 727
Woodbridge 391
Seattle 348
Cambridge 335
Wilmington 311
Houston 289
Dong Ket 233
Hong Kong 218
Princeton 184
Boston 138
Ann Arbor 134
Boardman 109
Altamura 105
Buffalo 81
Medford 81
Beijing 75
Lawrence 73
Seongnam 58
Washington 51
San Diego 48
Philadelphia 46
Milan 43
Florence 34
Norwalk 33
Phoenix 32
Shanghai 31
Frankfurt Am Main 30
West Jordan 30
Falls Church 27
Izmir 27
Kent 23
New York 22
Verona 21
Guangzhou 20
Los Angeles 20
Hillsboro 19
Andover 16
Lappeenranta 14
Salerno 11
Auburn Hills 10
Cedar Knolls 10
Tokyo 10
Toronto 10
Brussels 9
Dearborn 9
Singapore 9
Mcallen 7
Ottawa 7
Treviglio 7
Bern 6
Hanover 6
London 6
Kochi 5
Moncalieri 5
Munich 5
Napoli 5
Tappahannock 5
Frankfurt am Main 4
Giugliano In Campania 4
Palermo 4
Sesto Fiorentino 4
Vienna 4
Barcelona 3
Central 3
Chicago 3
Düsseldorf 3
Groningen 3
Kilburn 3
Laurel 3
Monza 3
Naaldwijk 3
Pozzuoli 3
San Martino Buon Albergo 3
Sassano 3
Seoul 3
Trumbull 3
Turate 3
Venice 3
Wroclaw 3
Arezzo 2
Aversa 2
Bengaluru 2
Bitonto 2
Bolzano 2
Bremen 2
Brindisi 2
Buccinasco 2
Calvisano 2
Casnate Con Bernate 2
Castelfranco Emilia 2
Ceppaloni 2
Easton 2
Edinburgh 2
Fisciano 2
Giugliano in Campania 2
Totale 11.390
Nome #
Antinociceptive property of the nicotinic agonist AG4 in rodents 431
DM235 (sunifiram): a novel nootropic with potential as a cognitive enhancer 318
Molecular simplification of 1,4-diazabicyclo[4.3.0]nonan-9-ones gives piperazine derivatives that maintain high nootropic activity 280
The novel nootropic compound DM232 (UNIFIRAM) ameliorates memory impairment in mice and rats 264
4-Aminopiperidine derivatives as a new class of potent cognition enhancing drugs 256
AG-4:A NICOTINIC AGONIST ENDOWED WITH ANTIAMNESIC PROPERTIES 251
S(-)ET126: a potent and selective M1 antagonist in vitro and in vivo 238
Antisense knockdowns of M1 receptors induces transient anterograde amnesia in mice 235
The functions and structure of ABC transporters: implications for the design of new inhibitors of Pgp and MRP1 to control multidrug resistance (MDR) 232
Memory facilitation with atropine: a paradoxical effect 229
Pharmacological characterization of DM232 (unifiram) and DM235 (sunifiram), new potent cognition-enhancers 227
Central muscarinic antinociception induced by ET-142 and SS-20 in rodents 226
IMPROVEMENT OF COGNITIVE FUNCTIONS BY THE ACETYLCHOLINE RELEASER SM21 224
Central cholinergic antinociception induced by 5HT4 agonists: BIMU 1 and BIMU 8 220
3-ALFA-TROPANYL 2-(4-Cl-PHENOXY)BUTIRATE (SM21): A REVIEW OF THE PHARMACOLOGICAL PROFILE OF A NOVEL ENHANCER OF CHOLINERGIC TRANSMISSION. 217
In vitro characterization of a novel, potent and selective M3 antagonist 216
PHARMACOLOGICAL CHARACTERIZATION OF THE NOVEL ACH RELEASER A-TROPANYL 2-(4-BROMOPHENYL)PROPIONATE (PG-9). 216
Presynaptic Cholinergic Modulators as Potent Cognition Enhancers and Analgesic Drugs. 2. 2-Phenoxy-, 2-(phenylthio)- and 2-(phenylamino)alkanoic Acid Esters 213
Antinociceptive profile of SM21: a novel analgesic with a presynaptic cholinergic mechanism of action 209
ANTINOCICEPTIVE EFFECT OF R-(+)-HYOSCYAMMINE ON THE CONJUNCTIVAL REFLEX TEST IN RABBITS 203
ANTINOCICEPTION INDUCED BY SM32 DEPENDS ON CENTRAL CHOLINERGIC MECHANISM 201
Design, synthesis and preliminary pharmacological evaluation of 1,4-diazabicyclo[4.3.0]nonan-9-ones as a new class of highly potent nootropic drugs. 193
Are the contractions of rabbit peripheral lung, guinea-pig gall-bladder and guinea-pig uterus mediated by identical receptor subtype? 193
Memory facilitation and stimulation of endogenous nerve growth factor synthesis by the ACh releaser PG9 190
Binding Profiles of a Series of 2-Arylpropionic Acid Esters on Cloned Human Muscarinic Receptors Subtypes (m1-m5) and Their Relationship to Nootropic Activity 183
Antinociceptive and antiamnesic properties of the presynaptic amplifier PG-9 179
THE FROZEN ANALOG APPROACH IN MEDICINAL CHEMISTRY 173
DESIGN, SYNTHESIS AND PRELIMINARY PHARMACOLOGICAL EVALUATION OF RIGID ANALOGUES OF THE NICOTINIC AGONIST 1,1-DIMETHYL-4-PHENYLPIPERAZINIUM IODIDE (DMPP) 155
1,2 BENZISOXAZOLES 135
Synthesis and Cholinergic Affinity of Diastereomeric and Enantiomeric Isomers of 1-Methyl-2-(2-methyl-1,3-dioxolan-4-yl)-pyrrolidine, 1-Methyl-2-(2-methyl-1,3-oxathiolan-5-yl)pyrrolidine and of Their Iodomethylates 112
Chiral synthesis and pharmacological evaluation of the enantiomers of SM32, a new analgesic and cognition-enhancing agent. 108
1,3-oxathiolane muscarinic ligands modified at the cationic head. 107
ISOMERIC N,N-BIS(CYCLOHEXANOL)AMINE ARYL ESTERS: THE DISCOVERY OF A NEW CLASS OF HIGHLY POTENT P-GLYCOPROTEIN (PGP)-DEPENDENT MULTIDRUG RESISTANCE (MDR) INHIBITORS 106
13C NMR SPECTRA OF 1,3-OXATHIOLANE, 1,3-OXATHIOLANE-3-OXIDE AND 1,3-OXATHIOLANE-3,3-DIOXIDE DERIVATIVES 105
Structure-affinity relationships of a unique nicotinic ligand: N1-dimethyl-N4-phenylpiperazinium iodide (DMPP) 104
Highly chiral muscarinic ligands: the discovery of (2S,2'R,3'S,5'R)-1-methyl-2-(2-methyl-1,3-oxathiolan-5-yl)pyrrolidine 3-sulfoxide methyl iodide, a potent, functionally selective, M2 partial agonist. 103
Synthesis and Enantioselectivity of the Enantiomers of PG9 and SM21, New Potent Analgesic and Cognition-Enhancing Drugs 100
CHOLINERGIC RECEPTORS AND NEURODEGENERATIVE DISEASES 100
SAR STUDIES ON THE POTENT AND SELECTIVE MUSCARINIC ANTAGONIST 2-ETHYLTHIO-2,2-DIPHENYLACETIC ACID N,N-DIETHYLAMINOETHYL ESTER 99
DIFFERENTIAL ANALGESIC ACTIVITY OF THE ENANTIOMERS OF ATROPINE DERIVATIVES DOES NOT CORRELATE WITH THEIR MUSCARINIC SUBTYPE SELECTIVITY 99
2-PYRROLIDINONE MOIETY IS NOT CRITICAL FOR THE COGNITION ENHANCING ACTIVITY OF PIRACETAM-LIKE DRUGS 97
The medicinal chemistry of multidrug resistance (MDR) reversing drugs 97
ANTIAMNESIC ACTIVITY OF METOCLOPRAMIDE, CISAPRIDE AND SR-17 IN THE MOUSE PASSIVE AVOIDANCE TEST 95
PRESYNAPTIC AUTO- AND HETERO-RECEPTORS IN THE CHOLINERGIC REGULATION OF PAIN 95
(1,3-Dioxolane)- and (1,3-oxathiolane)-2-pyrrolidines: molecular hybrids with potential anti-Alzheimer activity 95
Muscarinic subtype affinity and functional activity profile of 1-methyl-2-(2-methyl-1,3-dioxolan-4-yl)pyrrolidine and 1-methyl-2-(2-methyl-1,3-oxathiolan-5-yl)pyrrolidine derivatives. 94
SEMI-RIGID ANALOGUES OF THE CALCIUM ANTAGONIST VERAPAMIL: A MOLECULAR MODELLING STUDY 93
Central Nicotinic receptors: structure, function, ligands, and therapeutic potential 93
COGNITION-ENHANCING DRUGS IN MILD COGNITIVE IMPAIRMENT (MCI) AND ALZHEIMER'S DISEASE (AD): AN UPDATE[1] 92
RECENT ADVANCES IN RECEPTOR CHEMISTRY 91
Presynaptic Cholinergic Modulators as Potent Cognition Enhancers and Analgesic Drugs. 1. Tropic and 2-Phenylpropionic Acid Esters 89
NEGATIVE INOTROPIC ACTIVITY OF PARA-SUBSTITUTED DIETHYL BENZYL PHOSPHONATES RELATED TO FOSTEDIL 89
1,4-Diazabicyclo[4.3.0]nonan-9-ones and 1,4-diamidopiperazines as new classes of highly potent nootropic drugs 89
STRUCTURAL DEPENDENCE OF THE ALLOSTERIC INTERACTION OF SEMI-RIGID VERAPAMIL ANALOGUES WITH DIHYDROPYRIDINE-BINDING IN KITTEN HEART 88
S-(-)-ET126: a potent and selective M1 antagonist 88
REDUCED FLEXIBILITY ANALOGS OF ANALGESIC AND COGNITION-ENHANCING A-TROPANYL ESTERS 87
The novel nootropic drugs DM232 (Unifiram) and DM235 (Sunifiram) ameliorate memory impairment in mice and rats 87
Synthesis of Hexahydro-[2]pyrindine(=Hexahydrocyclopenta[c]pyridine) Derivatives as Conformationally Restricted Analogs of the Nicotinic Ligands Arecolone and Isoarecolone 87
VERAPAMIL ANALOGUES WITH RESTRICTED MOLECULAR FLEXIBILITY: SYNTHESIS AND PHARMACOLOGICAL EVALUATION OF THE FOUR ISOMERS OF ALPHA-[1-[3-[N-[1-[2-(3,4-DIMETHOXYPHENYL)ETHYL]]-N-METHYLAMINO]CYCLOHEXYL]]-ALPHA-ISOPROPYL-3,4-DIMETHOXYBENZENEACETONITRILE 86
Enantioselective synthesis and preliminary pharmacological evaluation of the enantiomers of unifiram (DM232), a potent cognition-enhancing agent 86
1,4-Diazabicyclo[4.3.0]nonan-9-ones as a new class of highly potent nootropic drugs 86
Design, synthesis and preliminary pharmacological evaluation of a set of small molecules that directly activate Gi proteins. 85
"Synthesis and binding properties of photoactivable Biotin-conjugated verapamil derivatives for the study of P-170 glycoprotein" 85
The quest for the treatment of cognitive impairment: alpha 7 nicotinic and alpha 5 GABA-A receptor modulators 84
Affinity and efficacy correlate with chemical structure more than potency does in a series of pentatomic cyclic muscarinic agonists 84
AMPA-receptor activation is involved in the antiamnesic effect of DM 232 (unifiram) and DM 235 (sunifiram). 83
A short synthesis of rigid 2-alkylthio-2,2-diaryl substituted acetic acids 83
Structure-activity relationships in 2,2-diphenyl-2-ethylthioacetic acid esters: unexpected agonistic activity in a series of muscarinic antagonists. 83
Design and study of piracetam-like nootropics, controversial members of the problematic class of cognition-enhancing drugs 82
CHIRALITY OF DRUG RECEPTOR INTERACTIONS: A SOURCE OF VALUABLE INFORMATION 81
Design, synthesis and preliminary pharmacological evaluation of 4-aminopiperidine derivatives as N-type calcium channel blockers active on pain and neuropathic pain 81
EUDISMIC ANALYSIS OF A SERIES OF MUSCARINIC LIGANDS CARRYING A 1,3-OXATHIOLANE NUCLEUS 78
25 Years later: latest news from the receptors 74
Effect of 5-HT4 agonists metoclopramide and Compound 1 on learning and memory 74
Design, synthesis and preliminary pharmacological evaluation of new analogues of DM232 (unifiram) and DM235 (sunifiram) as cognition modulators 73
MOLECULAR MODULATION OF MUSCARINIC ANTAGONISTS. SYNTHESIS AND PHARMACOLOGICAL PROFILE OF 2,2-DIPHENYL-2-ETHYLTHIOACETIC AND 3,3-DIPHENYL-3-ETHYLTHIOPROPIONIC ACID DERIVATIVES CHARACTERIZED BY A DIPEPTIDE SPACER 73
DISEGNO E SINTESI DI FARMACI E MEZZI DI INDAGINE FARMACOLOGICA 72
SYNTHESIS AND PHARMACOLOGICAL EVALUATION OF VERAPAMIL ANALOGS WITH RESTRICTED MOLECULAR FLEXIBILITY 72
Chiral muscarinic agonists possessing a 1,3-oxathiolane nucleus: enantio- and tissue-selectivity on isolated preparations of guinea-pig ileum and atria and of rat urinary bladder 72
Reversal of multidrug resistance by verapamil analogues 72
ANALGESIC, ANTIMUSCARINIC ACTIVITY AND ENANTIOSELECTIVITY OF THE FOUR ISOMERS OF 3-QUINUCLIDINYL TROPATE AS COMPARED WITH THE ENANTIOMERS OF HYOSCYAMINE 69
Enantioselectivity of muscarinic antagonists. Isomeric 2-Cyclohexyl-2-phenyl-5-((dimethylamino)methyl)-1,3-oxathiolane 3-Oxide Methiodides 69
SYNTHESIS AND BIOLOGICAL ACTIVITY OF A SERIES OF ARYL TROPANYL ESTERS AND AMIDES CHEMICALLY RELATED TO 1H-INDOLE-3-CARBOXYLIC ACID ENDO 8-METHYL-8-AZABICYCLO[3.2.1]OCT-3-YL ESTER 68
ORGANIC SYNTHESIS AND MEDICINAL CHEMISTRY 68
Differential analgesic activity of the enantiomers of atropine derivatives does not correlate with their muscarinic subtype selectivity 68
R-(+)-HYOSCYAMINE: A PERIPHERAL CHOLINERGIC AMPLIFER 66
MUSCARINIC PRESYNAPTIC AUTORECEPTORS AND MUSCARINIC POSTSYNAPTIC RECEPTORS HAVE OPPOSITE STEREOCHEMICAL REQUIREMENTS 64
Attività analgesica e antimuscarinica ed enantioselettività dei quattro isomeri del tropato del 3-chinuclidinolo messe a confronto con gli enantiomeri della iosciamina 63
A SEARCH FOR CALCIUM CHANNELS ACTIVATORS IN THE VERAPAMIL SERIES 62
A DIRECT METALLATION APPROACH TO 2-ALKYLTHIO-2,2-DIARYL SUBSTITUTED ACETIC ACIDS 61
NEGATIVE INOTROPIC AND CALCIUM ANTAGONISTIC ACTIVITY OF ALKYL AND ARYLALKYL PHOSPHONATES 61
Design, synthesis and pharmacological evaluation of some frozen-analogues of DMPP 61
N,N-DIETHYLAMINOETHANOL AND N-METHYL-4-PIPERIDINOL ESTERS OF 2,2-DIPHENYL-2-ETHYLTHIOACETIC ACID AS POTENT AND SELECTIVE MUSCARINIC ANTAGONISTS 60
N,N-bis(alkanol)amine aryl esters and N,N-bis(cyclohexanol)amine aryl esters: Idantification of a new class of Pgp-dependent multidrug resistance (MDR) reverters andowed with potencies in the nanomolar range 60
LO STATO DELL'ARTE E LE PROSPETTIVE DI SVILUPPO DEI FARMACI PER LE DISFUNZIONI COGNITIVE 59
CHOLINERGIC ANTAGONISTS CARRYING A 1,3-OXATHIOLANE NUCLEUS 59
Exploratory chemistry toward the identification of a new class of MDR reverters inspired by pervilleine and verapamil models 58
Design, synthesis, and in vitro acivity of catamphiphilic reverters of multidrug resistance: discovery of selective, highly efficacious chemosensitizer with potency in the nanomolar range 58
REDUCED-FLEXIBILITY HYBRIDS OF THE NICOTINIC AGONISTS 1,1-DIMETHYL-4-ACETYLPIPERAZINIUM IODIDE AND 2-(DIMETHYLAMINO)METHYL-5-CYCLOPENTANONE METHIODIDE 57
ENANTIOSELECTIVITY OF CHIRAL CHOLINERGIC AGONISTS AND ANTAGONISTS CARRYING A 1,3-OXATHIOLANE NUCLEUS 56
Totale 12.292
Categoria #
all - tutte 36.213
article - articoli 0
book - libri 0
conference - conferenze 0
curatela - curatele 0
other - altro 0
patent - brevetti 0
selected - selezionate 0
volume - volumi 0
Totale 36.213


Totale Lug Ago Sett Ott Nov Dic Gen Feb Mar Apr Mag Giu
2018/2019311 0 0 0 0 0 0 0 0 0 0 0 311
2019/20202.852 239 327 92 268 289 330 221 380 207 148 303 48
2020/20212.480 170 158 181 254 80 353 88 230 170 323 101 372
2021/20221.180 32 176 55 52 42 39 37 74 38 33 271 331
2022/20232.899 290 352 104 279 281 582 363 204 289 17 99 39
2023/20241.608 54 133 241 79 104 340 46 471 25 43 38 34
Totale 15.082