GUALTIERI, FULVIO
 Distribuzione geografica
Salva come PNG Salva come JPEG
Continente #
EU - Europa 6776
NA - Nord America 6001
AS - Asia 461
AF - Africa 34
Continente sconosciuto - Info sul continente non disponibili 1
Totale 13273
Salva come PNG Salva come JPEG
Nazione #
US - Stati Uniti d'America 5983
PL - Polonia 3483
SE - Svezia 834
IE - Irlanda 656
UA - Ucraina 520
IT - Italia 500
DE - Germania 314
VN - Vietnam 237
FI - Finlandia 183
GB - Regno Unito 173
CN - Cina 89
KR - Corea 67
FR - Francia 42
SC - Seychelles 29
TR - Turchia 28
JO - Giordania 27
NL - Olanda 20
CA - Canada 18
AT - Austria 14
BE - Belgio 10
RO - Romania 8
HR - Croazia 4
IN - India 4
RU - Federazione Russa 4
CZ - Repubblica Ceca 3
ES - Italia 3
JP - Giappone 3
DZ - Algeria 2
IR - Iran 2
MU - Mauritius 2
AM - Armenia 1
CH - Svizzera 1
EU - Europa 1
KE - Kenya 1
LB - Libano 1
LU - Lussemburgo 1
LV - Lettonia 1
MD - Moldavia 1
PH - Filippine 1
SK - Slovacchia (Repubblica Slovacca) 1
UZ - Uzbekistan 1
Totale 13273
Salva come PNG Salva come JPEG
Città #
Warsaw 3480
Chandler 825
Fairfield 779
Jacksonville 739
Dublin 656
Woodbridge 391
Ashburn 362
Seattle 343
Cambridge 335
Wilmington 311
Houston 289
Dong Ket 233
Princeton 184
Boston 138
Ann Arbor 134
Altamura 105
Buffalo 81
Medford 81
Lawrence 73
Boardman 70
Beijing 67
Seongnam 58
San Diego 48
Philadelphia 46
Milan 37
Norwalk 33
Frankfurt Am Main 30
Phoenix 30
Florence 28
Falls Church 27
Izmir 27
Verona 21
Guangzhou 20
Los Angeles 18
Andover 16
Salerno 11
Vienna 11
Auburn Hills 10
Brussels 10
Cedar Knolls 10
Toronto 10
Dearborn 9
Mcallen 7
Ottawa 7
Treviglio 7
London 5
Munich 5
Napoli 5
Giugliano In Campania 4
Hanover 4
Barcelona 3
Düsseldorf 3
Groningen 3
Laurel 3
Naaldwijk 3
Pozzuoli 3
Seoul 3
Trumbull 3
Venice 3
Wroclaw 3
Bitonto 2
Bremen 2
Brindisi 2
Calvisano 2
Ceppaloni 2
Chicago 2
Easton 2
Fisciano 2
Leawood 2
Mayen 2
Montefredane 2
Murfreesboro 2
Prague 2
Redmond 2
Redwood City 2
Sesto Fiorentino 2
Sorrento 2
Tokyo 2
Trento 2
Aalen 1
Anguillara Sabazia 1
Augusta 1
Avellino 1
Bacoli 1
Bovisio 1
Bucharest 1
Camerino 1
Chestnut Hill 1
Chisinau 1
Cinisello Balsamo 1
Como 1
Cypress 1
Dallas 1
Eugene 1
Ferrara di Monte Baldo 1
Fiesole 1
Frankfurt am Main 1
Frattamaggiore 1
Fucecchio 1
Grafing 1
Totale 10319
Salva come PNG Salva come JPEG
Nome #
DM235 (sunifiram): a novel nootropic with potential as a cognitive enhancer 270
Molecular simplification of 1,4-diazabicyclo[4.3.0]nonan-9-ones gives piperazine derivatives that maintain high nootropic activity 266
The novel nootropic compound DM232 (UNIFIRAM) ameliorates memory impairment in mice and rats 250
4-Aminopiperidine derivatives as a new class of potent cognition enhancing drugs 242
AG-4:A NICOTINIC AGONIST ENDOWED WITH ANTIAMNESIC PROPERTIES 234
The functions and structure of ABC transporters: implications for the design of new inhibitors of Pgp and MRP1 to control multidrug resistance (MDR) 223
IMPROVEMENT OF COGNITIVE FUNCTIONS BY THE ACETYLCHOLINE RELEASER SM21 221
Antisense knockdowns of M1 receptors induces transient anterograde amnesia in mice 221
Memory facilitation with atropine: a paradoxical effect 218
Pharmacological characterization of DM232 (unifiram) and DM235 (sunifiram), new potent cognition-enhancers 217
Central muscarinic antinociception induced by ET-142 and SS-20 in rodents 214
Central cholinergic antinociception induced by 5HT4 agonists: BIMU 1 and BIMU 8 212
Antinociceptive property of the nicotinic agonist AG4 in rodents 212
PHARMACOLOGICAL CHARACTERIZATION OF THE NOVEL ACH RELEASER A-TROPANYL 2-(4-BROMOPHENYL)PROPIONATE (PG-9). 211
S(-)ET126: a potent and selective M1 antagonist in vitro and in vivo 208
Presynaptic Cholinergic Modulators as Potent Cognition Enhancers and Analgesic Drugs. 2. 2-Phenoxy-, 2-(phenylthio)- and 2-(phenylamino)alkanoic Acid Esters 207
In vitro characterization of a novel, potent and selective M3 antagonist 205
3-ALFA-TROPANYL 2-(4-Cl-PHENOXY)BUTIRATE (SM21): A REVIEW OF THE PHARMACOLOGICAL PROFILE OF A NOVEL ENHANCER OF CHOLINERGIC TRANSMISSION. 200
Antinociceptive profile of SM21: a novel analgesic with a presynaptic cholinergic mechanism of action 199
ANTINOCICEPTION INDUCED BY SM32 DEPENDS ON CENTRAL CHOLINERGIC MECHANISM 190
Design, synthesis and preliminary pharmacological evaluation of 1,4-diazabicyclo[4.3.0]nonan-9-ones as a new class of highly potent nootropic drugs. 187
ANTINOCICEPTIVE EFFECT OF R-(+)-HYOSCYAMMINE ON THE CONJUNCTIVAL REFLEX TEST IN RABBITS 187
Are the contractions of rabbit peripheral lung, guinea-pig gall-bladder and guinea-pig uterus mediated by identical receptor subtype? 187
Memory facilitation and stimulation of endogenous nerve growth factor synthesis by the ACh releaser PG9 180
Binding Profiles of a Series of 2-Arylpropionic Acid Esters on Cloned Human Muscarinic Receptors Subtypes (m1-m5) and Their Relationship to Nootropic Activity 172
Antinociceptive and antiamnesic properties of the presynaptic amplifier PG-9 172
THE FROZEN ANALOG APPROACH IN MEDICINAL CHEMISTRY 162
DESIGN, SYNTHESIS AND PRELIMINARY PHARMACOLOGICAL EVALUATION OF RIGID ANALOGUES OF THE NICOTINIC AGONIST 1,1-DIMETHYL-4-PHENYLPIPERAZINIUM IODIDE (DMPP) 139
1,2 BENZISOXAZOLES 105
Synthesis and Cholinergic Affinity of Diastereomeric and Enantiomeric Isomers of 1-Methyl-2-(2-methyl-1,3-dioxolan-4-yl)-pyrrolidine, 1-Methyl-2-(2-methyl-1,3-oxathiolan-5-yl)pyrrolidine and of Their Iodomethylates 103
Chiral synthesis and pharmacological evaluation of the enantiomers of SM32, a new analgesic and cognition-enhancing agent. 99
Highly chiral muscarinic ligands: the discovery of (2S,2'R,3'S,5'R)-1-methyl-2-(2-methyl-1,3-oxathiolan-5-yl)pyrrolidine 3-sulfoxide methyl iodide, a potent, functionally selective, M2 partial agonist. 98
Structure-affinity relationships of a unique nicotinic ligand: N1-dimethyl-N4-phenylpiperazinium iodide (DMPP) 97
1,3-oxathiolane muscarinic ligands modified at the cationic head. 97
13C NMR SPECTRA OF 1,3-OXATHIOLANE, 1,3-OXATHIOLANE-3-OXIDE AND 1,3-OXATHIOLANE-3,3-DIOXIDE DERIVATIVES 93
CHOLINERGIC RECEPTORS AND NEURODEGENERATIVE DISEASES 93
SAR STUDIES ON THE POTENT AND SELECTIVE MUSCARINIC ANTAGONIST 2-ETHYLTHIO-2,2-DIPHENYLACETIC ACID N,N-DIETHYLAMINOETHYL ESTER 92
ISOMERIC N,N-BIS(CYCLOHEXANOL)AMINE ARYL ESTERS: THE DISCOVERY OF A NEW CLASS OF HIGHLY POTENT P-GLYCOPROTEIN (PGP)-DEPENDENT MULTIDRUG RESISTANCE (MDR) INHIBITORS 92
ANTIAMNESIC ACTIVITY OF METOCLOPRAMIDE, CISAPRIDE AND SR-17 IN THE MOUSE PASSIVE AVOIDANCE TEST 91
Synthesis and Enantioselectivity of the Enantiomers of PG9 and SM21, New Potent Analgesic and Cognition-Enhancing Drugs 91
2-PYRROLIDINONE MOIETY IS NOT CRITICAL FOR THE COGNITION ENHANCING ACTIVITY OF PIRACETAM-LIKE DRUGS 89
DIFFERENTIAL ANALGESIC ACTIVITY OF THE ENANTIOMERS OF ATROPINE DERIVATIVES DOES NOT CORRELATE WITH THEIR MUSCARINIC SUBTYPE SELECTIVITY 89
The medicinal chemistry of multidrug resistance (MDR) reversing drugs 87
PRESYNAPTIC AUTO- AND HETERO-RECEPTORS IN THE CHOLINERGIC REGULATION OF PAIN 86
Muscarinic subtype affinity and functional activity profile of 1-methyl-2-(2-methyl-1,3-dioxolan-4-yl)pyrrolidine and 1-methyl-2-(2-methyl-1,3-oxathiolan-5-yl)pyrrolidine derivatives. 85
SEMI-RIGID ANALOGUES OF THE CALCIUM ANTAGONIST VERAPAMIL: A MOLECULAR MODELLING STUDY 84
COGNITION-ENHANCING DRUGS IN MILD COGNITIVE IMPAIRMENT (MCI) AND ALZHEIMER'S DISEASE (AD): AN UPDATE[1] 84
RECENT ADVANCES IN RECEPTOR CHEMISTRY 84
STRUCTURAL DEPENDENCE OF THE ALLOSTERIC INTERACTION OF SEMI-RIGID VERAPAMIL ANALOGUES WITH DIHYDROPYRIDINE-BINDING IN KITTEN HEART 83
NEGATIVE INOTROPIC ACTIVITY OF PARA-SUBSTITUTED DIETHYL BENZYL PHOSPHONATES RELATED TO FOSTEDIL 82
REDUCED FLEXIBILITY ANALOGS OF ANALGESIC AND COGNITION-ENHANCING A-TROPANYL ESTERS 81
(1,3-Dioxolane)- and (1,3-oxathiolane)-2-pyrrolidines: molecular hybrids with potential anti-Alzheimer activity 80
VERAPAMIL ANALOGUES WITH RESTRICTED MOLECULAR FLEXIBILITY: SYNTHESIS AND PHARMACOLOGICAL EVALUATION OF THE FOUR ISOMERS OF ALPHA-[1-[3-[N-[1-[2-(3,4-DIMETHOXYPHENYL)ETHYL]]-N-METHYLAMINO]CYCLOHEXYL]]-ALPHA-ISOPROPYL-3,4-DIMETHOXYBENZENEACETONITRILE 79
Central Nicotinic receptors: structure, function, ligands, and therapeutic potential 79
Presynaptic Cholinergic Modulators as Potent Cognition Enhancers and Analgesic Drugs. 1. Tropic and 2-Phenylpropionic Acid Esters 78
Design, synthesis and preliminary pharmacological evaluation of a set of small molecules that directly activate Gi proteins. 78
The quest for the treatment of cognitive impairment: alpha 7 nicotinic and alpha 5 GABA-A receptor modulators 76
Affinity and efficacy correlate with chemical structure more than potency does in a series of pentatomic cyclic muscarinic agonists 76
Design and study of piracetam-like nootropics, controversial members of the problematic class of cognition-enhancing drugs 76
CHIRALITY OF DRUG RECEPTOR INTERACTIONS: A SOURCE OF VALUABLE INFORMATION 74
Enantioselective synthesis and preliminary pharmacological evaluation of the enantiomers of unifiram (DM232), a potent cognition-enhancing agent 74
Structure-activity relationships in 2,2-diphenyl-2-ethylthioacetic acid esters: unexpected agonistic activity in a series of muscarinic antagonists. 72
Synthesis of Hexahydro-[2]pyrindine(=Hexahydrocyclopenta[c]pyridine) Derivatives as Conformationally Restricted Analogs of the Nicotinic Ligands Arecolone and Isoarecolone 72
EUDISMIC ANALYSIS OF A SERIES OF MUSCARINIC LIGANDS CARRYING A 1,3-OXATHIOLANE NUCLEUS 72
"Synthesis and binding properties of photoactivable Biotin-conjugated verapamil derivatives for the study of P-170 glycoprotein" 72
A short synthesis of rigid 2-alkylthio-2,2-diaryl substituted acetic acids 71
1,4-Diazabicyclo[4.3.0]nonan-9-ones and 1,4-diamidopiperazines as new classes of highly potent nootropic drugs 71
SYNTHESIS AND PHARMACOLOGICAL EVALUATION OF VERAPAMIL ANALOGS WITH RESTRICTED MOLECULAR FLEXIBILITY 70
1,4-Diazabicyclo[4.3.0]nonan-9-ones as a new class of highly potent nootropic drugs 70
Design, synthesis and preliminary pharmacological evaluation of 4-aminopiperidine derivatives as N-type calcium channel blockers active on pain and neuropathic pain 69
AMPA-receptor activation is involved in the antiamnesic effect of DM 232 (unifiram) and DM 235 (sunifiram). 68
MOLECULAR MODULATION OF MUSCARINIC ANTAGONISTS. SYNTHESIS AND PHARMACOLOGICAL PROFILE OF 2,2-DIPHENYL-2-ETHYLTHIOACETIC AND 3,3-DIPHENYL-3-ETHYLTHIOPROPIONIC ACID DERIVATIVES CHARACTERIZED BY A DIPEPTIDE SPACER 68
Design, synthesis and preliminary pharmacological evaluation of new analogues of DM232 (unifiram) and DM235 (sunifiram) as cognition modulators 67
Effect of 5-HT4 agonists metoclopramide and Compound 1 on learning and memory 67
Chiral muscarinic agonists possessing a 1,3-oxathiolane nucleus: enantio- and tissue-selectivity on isolated preparations of guinea-pig ileum and atria and of rat urinary bladder 66
25 Years later: latest news from the receptors 65
Enantioselectivity of muscarinic antagonists. Isomeric 2-Cyclohexyl-2-phenyl-5-((dimethylamino)methyl)-1,3-oxathiolane 3-Oxide Methiodides 64
Reversal of multidrug resistance by verapamil analogues 64
ORGANIC SYNTHESIS AND MEDICINAL CHEMISTRY 62
S-(-)-ET126: a potent and selective M1 antagonist 60
ANALGESIC, ANTIMUSCARINIC ACTIVITY AND ENANTIOSELECTIVITY OF THE FOUR ISOMERS OF 3-QUINUCLIDINYL TROPATE AS COMPARED WITH THE ENANTIOMERS OF HYOSCYAMINE 59
A DIRECT METALLATION APPROACH TO 2-ALKYLTHIO-2,2-DIARYL SUBSTITUTED ACETIC ACIDS 59
DISEGNO E SINTESI DI FARMACI E MEZZI DI INDAGINE FARMACOLOGICA 57
Differential analgesic activity of the enantiomers of atropine derivatives does not correlate with their muscarinic subtype selectivity 57
N,N-DIETHYLAMINOETHANOL AND N-METHYL-4-PIPERIDINOL ESTERS OF 2,2-DIPHENYL-2-ETHYLTHIOACETIC ACID AS POTENT AND SELECTIVE MUSCARINIC ANTAGONISTS 55
SYNTHESIS AND BIOLOGICAL ACTIVITY OF A SERIES OF ARYL TROPANYL ESTERS AND AMIDES CHEMICALLY RELATED TO 1H-INDOLE-3-CARBOXYLIC ACID ENDO 8-METHYL-8-AZABICYCLO[3.2.1]OCT-3-YL ESTER 55
A SEARCH FOR CALCIUM CHANNELS ACTIVATORS IN THE VERAPAMIL SERIES 55
CHOLINERGIC ANTAGONISTS CARRYING A 1,3-OXATHIOLANE NUCLEUS 55
Design, synthesis and pharmacological evaluation of some frozen-analogues of DMPP 53
NEGATIVE INOTROPIC AND CALCIUM ANTAGONISTIC ACTIVITY OF ALKYL AND ARYLALKYL PHOSPHONATES 52
ENANTIOSELECTIVITY OF CHIRAL CHOLINERGIC AGONISTS AND ANTAGONISTS CARRYING A 1,3-OXATHIOLANE NUCLEUS 52
MUSCARINIC PRESYNAPTIC AUTORECEPTORS AND MUSCARINIC POSTSYNAPTIC RECEPTORS HAVE OPPOSITE STEREOCHEMICAL REQUIREMENTS 51
VERAPAMIL ANALOGUES WITH RESTRICTED MOLECULAR FLEXIBILITY 50
Exploratory chemistry toward the identification of a new class of MDR reverters inspired by pervilleine and verapamil models 50
LO STATO DELL'ARTE E LE PROSPETTIVE DI SVILUPPO DEI FARMACI PER LE DISFUNZIONI COGNITIVE 49
REDUCED-FLEXIBILITY HYBRIDS OF THE NICOTINIC AGONISTS 1,1-DIMETHYL-4-ACETYLPIPERAZINIUM IODIDE AND 2-(DIMETHYLAMINO)METHYL-5-CYCLOPENTANONE METHIODIDE 49
THE MEDICINAL CHEMISTRY OF ALZHEIMER'S AND ALZHEIMER-LIKE DISEASES WITH EMPHASIS ON THE CHOLINERGIC HYPOTHESIS 48
SAR STUDIES IN THE FIELD OF CA2+ ANTAGONISTS. EFFECT OF MODIFICATIONS AT THE TETRASUBSTITUTED CARBON OF VERAPAMIL-LIKE COMPOUNDS 48
The novel nootropic drugs DM232 (Unifiram) and DM235 (Sunifiram) ameliorate memory impairment in mice and rats 48
PFEIFFER'S RULE AND EUDISMIC ANALYSIS: STRESSING THE HOMOGENEITY OF DATA 46
Totale 10999
Salva come PNG Salva come JPEG
Categoria #
all - tutte 20326
article - articoli 0
book - libri 0
conference - conferenze 0
curatela - curatele 0
other - altro 0
patent - brevetti 0
selected - selezionate 0
volume - volumi 0
Totale 20326
Salva come PNG Salva come JPEG


Totale Lug Ago Sett Ott Nov Dic Gen Feb Mar Apr Mag Giu
2017/2018690 0000 00 00 219225139107
2018/20191806 576811464 22282 10064 109192423311
2019/20202852 23932792268 289330 221380 20714830348
2020/20212480 170158181254 80353 88230 170323101372
2021/20221180 321765552 4239 3774 3833271331
2022/20232819 290352104279 281582 427214 290000
Totale 13394