CARTA, FABRIZIO
 Distribuzione geografica
Continente #
NA - Nord America 22.093
EU - Europa 12.314
AS - Asia 9.897
SA - Sud America 2.056
Continente sconosciuto - Info sul continente non disponibili 396
AF - Africa 298
OC - Oceania 133
Totale 47.187
Nazione #
US - Stati Uniti d'America 21.634
RU - Federazione Russa 3.573
PL - Polonia 2.974
IT - Italia 2.862
SG - Singapore 2.608
CN - Cina 2.501
BR - Brasile 1.633
HK - Hong Kong 1.230
VN - Vietnam 1.173
KR - Corea 921
IE - Irlanda 872
SE - Svezia 517
IN - India 403
FR - Francia 343
BD - Bangladesh 286
FI - Finlandia 283
CA - Canada 265
DE - Germania 244
GB - Regno Unito 227
ID - Indonesia 168
AR - Argentina 151
AU - Australia 129
JP - Giappone 100
NL - Olanda 93
MX - Messico 89
TR - Turchia 88
JO - Giordania 83
ES - Italia 80
EC - Ecuador 75
UA - Ucraina 68
CO - Colombia 60
CI - Costa d'Avorio 56
IQ - Iraq 56
NG - Nigeria 52
ZA - Sudafrica 42
PK - Pakistan 40
PY - Paraguay 38
UZ - Uzbekistan 35
VE - Venezuela 34
CH - Svizzera 33
MA - Marocco 31
EG - Egitto 28
PH - Filippine 27
CL - Cile 26
SA - Arabia Saudita 26
CZ - Repubblica Ceca 21
TW - Taiwan 20
UY - Uruguay 20
BE - Belgio 19
BJ - Benin 18
MY - Malesia 18
CR - Costa Rica 17
AE - Emirati Arabi Uniti 16
JM - Giamaica 16
KZ - Kazakistan 16
AT - Austria 15
KE - Kenya 15
TN - Tunisia 14
DO - Repubblica Dominicana 13
DZ - Algeria 13
AL - Albania 12
AZ - Azerbaigian 12
HN - Honduras 12
RO - Romania 12
LT - Lituania 11
PE - Perù 11
BG - Bulgaria 10
DK - Danimarca 9
NP - Nepal 9
GT - Guatemala 8
SN - Senegal 8
IL - Israele 7
NI - Nicaragua 7
PT - Portogallo 7
BO - Bolivia 6
ET - Etiopia 6
IR - Iran 6
OM - Oman 6
AO - Angola 5
EE - Estonia 5
PA - Panama 5
TH - Thailandia 5
BB - Barbados 4
EU - Europa 4
KG - Kirghizistan 4
KW - Kuwait 4
NZ - Nuova Zelanda 4
PR - Porto Rico 4
QA - Qatar 4
RS - Serbia 4
SV - El Salvador 4
SY - Repubblica araba siriana 4
TT - Trinidad e Tobago 4
AM - Armenia 3
BA - Bosnia-Erzegovina 3
BY - Bielorussia 3
GR - Grecia 3
LB - Libano 3
LV - Lettonia 3
SK - Slovacchia (Repubblica Slovacca) 3
Totale 46.752
Città #
Santa Clara 3.459
Warsaw 2.966
Ashburn 2.827
Fairfield 2.308
Singapore 1.941
Woodbridge 1.049
Hong Kong 1.004
Seattle 966
Seoul 909
Cambridge 900
San Jose 875
Houston 868
Dublin 856
Wilmington 729
Hefei 700
Chandler 505
Milan 494
Altamura 415
Lawrence 390
Beijing 387
Council Bluffs 385
Ann Arbor 383
Ho Chi Minh City 369
Florence 341
Los Angeles 276
Princeton 270
Rome 260
Hanoi 255
Dallas 254
Lauterbourg 246
Moscow 243
The Dalles 221
Buffalo 182
New York 154
Boston 151
Mumbai 148
Phoenix 129
São Paulo 129
Medford 124
Melbourne 118
Boardman 111
Clifton 111
San Diego 106
Kent 104
Jakarta 95
Helsinki 94
Tokyo 88
Naples 86
Chicago 80
Munich 80
Dong Ket 79
Shanghai 74
Redondo Beach 62
Paris 61
Abidjan 55
London 55
Barcelona 52
Toronto 52
Turku 52
Frankfurt am Main 51
Turin 51
Abuja 50
Da Nang 50
Haiphong 49
Rio de Janeiro 49
Brasília 44
Jacksonville 43
Atlanta 42
Norwalk 42
Orem 42
Figino 41
Bologna 40
Bengaluru 39
Gavirate 39
Guangzhou 39
Montreal 38
Biên Hòa 37
Falls Church 37
Belo Horizonte 32
Brooklyn 32
Delhi 32
Lappeenranta 32
Mexico City 31
Bern 30
Tashkent 30
Guayaquil 29
Hillsboro 29
Hyderabad 28
New Delhi 28
Porto Alegre 28
Tampa 28
Denver 27
Istanbul 26
Miano 26
Philadelphia 26
Quito 26
Izmir 25
Amsterdam 24
Andover 24
Shenzhen 24
Totale 32.123
Nome #
Ureido-Substituted Benzenesulfonamides Potently Inhibit Carbonic Anhydrase IX and Show Antimetastatic Activity in a Model of Breast Cancer Metastasis 390
Polyamines inhibit carbonic anhydrases by anchoring to the zinc-coordinated water molecule. 348
Assembly comprising an absorber of near infrared (nir) light covalently linked to an inhibitor of carbonic anhydrase 341
Dithiocarbamates: a new class of carbonic anhydrase inhibitors. Crystallographic and kinetic investigations. 301
CO2 and HCO3- Permeability of the Rat Liver Mitochondrial Membrane 289
7-Amino-3,4-dihydro-1H-quinolin-2-one, a compound similar to the substituted coumarins, inhibits α-carbonic anhydrases without hydrolysis of the lactam ring. 285
A potentiated cooperation of carbonic anhydrase IX and histone deacetylase inhibitors against cancer 275
Mono-/dihydroxybenzoic acid esters and phenol pyridinium derivatives as inhibitors of the mammalian carbonic anhydrase isoforms I, II, VII, IX, XII and XIV. 274
Heterocoumarins Are Selective Carbonic Anhydrase IX and XII Inhibitors with Cytotoxic Effects against Cancer Cells Lines 273
Dithiocarbamates with potent inhibitory activity against the Saccharomyces cerevisiae β-carbonic anhydrase 265
A New Kid on the Block? Carbonic Anhydrases as Possible New Targets in Alzheimer's Disease 258
Diuretics with carbonic anhydrase inhibitory action: A patent and literature review (2005-2013) 258
BRAIN CARBONIC ANHYDRASES INHIBITION IMPAIRS FEAR MEMORY EXTINCTION IN RATS 253
4-Arylbenzenesulfonamides as Human Carbonic Anhydrase Inhibitors (hCAIs): Synthesis by Pd Nanocatalyst-Mediated Suzuki-Miyaura Reaction, Enzyme Inhibition, and X-ray Crystallographic Studies 251
Lead Development of Thiazolylsulfonamides with Carbonic Anhydrase Inhibitory Action 246
Synthesis of new 3-(2-mercapto-4-oxo-4H-quinazolin-3-yl)-benzenesulfonamides with strong inhibition properties against the tumor associated carbonic anhydrases IX and XII 241
Design, Synthesis, and X-ray of Selenides as New Class of Agents for Prevention of Diabetic Cerebrovascular Pathology 238
Next-generation dithiocarbamate carbonic anhydrase inhibitors 235
Carbonic anhydrase activation enhances object recognition memory in mice through phosphorylation of the extracellular signal-regulated kinase in the cortex and the hippocampus. 233
Design and synthesis of novel indole β-diketo acid derivatives as HIV-1 integrase inhibitors 232
Design and synthesis of novel dihydroxyindole-2-carboxylic acids as HIV-1 integrase inhibitors 232
7-Substituted-sulfocoumarins are isoform-selective, potent carbonic anhydrase II inhibitors. 231
Blocking HIF signaling via novel inhibitors of CA9 and APE1/Ref-1 dramatically affects pancreatic cancer cell survival 231
Searching for intermediates in Prins cyclisations: The 2-oxa-5-adamantyl carbocation 230
Discovery of β-Adrenergic Receptors Blocker-Carbonic Anhydrase Inhibitor Hybrids for Multitargeted Antiglaucoma Therapy 229
Pain relieving effect of-NSAIDS-CAIs hybrid molecules: Systemic and intra-articular treatments against rheumatoid arthritis 229
Exploring QSARs of some benzenesulfonamides incorporating cyanoacrylamide moieties as a carbonic anhydrase inhibitors (specifically against tumor-associated isoforms IX and XII) 229
The carbonic anhydrase IX inhibitor SLC-0111 sensitises cancer cells to conventional chemotherapy 226
Discovery of New Selenoureido Analogues of 4-(4-Fluorophenylureido)benzenesulfonamide as Carbonic Anhydrase Inhibitors 223
Structure activity study of carbonic anhydrase IX: Selective inhibition with ureido-substituted benzenesulfonamides 222
Design, synthesis, molecular modeling, and anti-HIV-1 integrase activity of a series of photoactivatable diketo acid-containing inhibitors as affinity probes 221
Discovery of 4-Hydroxy-3-(3-(phenylureido)benzenesulfonamides as SLC-0111 Analogues for the Treatment of Hypoxic Tumors Overexpressing Carbonic Anhydrase IX 220
Structural modulation of the biological activity of gold nanoparticles functionalized with a carbonic anhydrase inhibitor. 219
[(Cp-R)M(CO)(3) ] (M=Re or (99m) Tc) Arylsulfonamide, Arylsulfamide, and Arylsulfamate Conjugates for Selective Targeting of Human Carbonic Anhydrase IX. 218
A class of sulfonamide carbonic anhydrase inhibitors with neuropathic pain modulating effects 218
Carbonic anhydrase IX inhibition affects viability of cancer cells adapted to extracellular acidosis 218
Structural Investigation of 3,5-Disubstituted Isoxazoles by1H-Nuclear Magnetic Resonance 218
Pain Relieving Eect of-NSAIDs-CAIs Hybrid Molecules: Systemic and Intra-Articular Treatments against Rheumatoid Arthritis 217
Chalcogenides-incorporating carbonic anhydrase inhibitors concomitantly reverted oxaliplatin-induced neuropathy and enhanced antiproliferative action 217
A class of 4-Sulfamoylphenyl-ω-aminoalkyl ethers with effective carbonic anhydrase inhibitory action and antiglaucoma effects. 215
Novel small molecule protein arginine deiminase 4 (PAD4) inhibitors 215
From ligand to complexes. Part 2. Remarks on human immunodeficiency virus type 1 integrase inhibition by β-diketo acid metal complexes 215
Structural effect of phenyl ring compared to thiadiazole based adamantyl-sulfonamides on carbonic anhydrase inhibition 212
Effects of new nsaid-cai hybrid compounds in inflammation and lung fibrosis 211
Novel sulfamide-containing compounds as selective carbonic anhydrase i inhibitors 211
7-Aryl-triazolyl-substituted sulfocoumarins are potent, selective inhibitors of the tumor-associated carbonic anhydrase IX and XII 211
Mycobacterium tuberculosisβ-Carbonic Anhydrases: Novel Targets for Developing Antituberculosis Drugs 210
5- and 6-membered (thio)lactones are prodrug type carbonic anhydrase inhibitors. 209
Advances in New Psychoactive Substances Identification: The U.R.I.To.N Consortium 209
Benzenesulfonamides Incorporating Flexible Triazole Moieties Are Highly Effective Carbonic Anhydrase Inhibitors: Synthesis and Kinetic, Crystallographic, Computational, and Intraocular Pressure Lowering Investigations 207
Deciphering the Mechanism of Human Carbonic Anhydrases Inhibition with Sulfocoumarins: Computational and Experimental Studies 207
6-Substituted 1,2-benzoxathiine-2,2-dioxides are isoform-selective inhibitors of human carbonic anhydrases IX, XII and VA. 206
Carbonic anhydrase IX from cancer-associated fibroblasts drives epithelial-mesenchymal transition in prostate carcinoma cells 206
In vitro inhibition of Mycobacterium tuberculosis β-carbonic anhydrase 3 with Mono- and dithiocarbamates and evaluation of their toxicity using zebrafish developing embryos 205
6-substituted sulfocoumarins are selective carbonic anhdydrase IX and XII Inhibitors with significant cytotoxicity against colorectal cancer cells 205
Next-generation polyamine human carbonic anhydrase inhibitors 203
Carbonic anhydrase inhibitors based on sorafenib scaffold: Design, synthesis, crystallographic investigation and effects on primary breast cancer cells 202
Cyclodextrin complexation highly enhances efficacy of arylsulfonylureido benzenesulfonamide carbonic anhydrase inhibitors as a topical antiglaucoma agents 202
Antiobesity carbonic anhydrase inhibitors: a literature and patent review. 201
Overexpression of the transmembrane carbonic anhydrase isoforms IX and XII in the inflamed synovium 201
Synthesis and evaluation of carbonic anhydrase inhibitors with carbon monoxide releasing properties for the management of rheumatoid arthritis 199
Antiglaucoma carbonic anhydrase inhibitors: a patent review. 199
A CARBONIC ANHYDRASE INHIBITOR COMPRISING A DITHIOCARBAMATE 198
Click-tailed coumarins with potent and selective inhibitory action against the tumor-associated carbonic anhydrases IX and XII 198
Polyamines and α-carbonic anhydrases 198
Design of novel bioisosteres of β-diketo acid inhibitors of HIV-1 integrase 197
Evaluation of Thio- and Seleno-Acetamides Bearing Benzenesulfonamide as Inhibitor of Carbonic Anhydrases from Different Pathogenic Bacteria 197
Plasmonic Particles that Hit Hypoxic Cells 196
Mechanisms of the Antiproliferative and Antitumor Activity of Novel Telomerase-Carbonic Anhydrase Dual-Hybrid Inhibitors 194
Antimalarial Agents Targeting Plasmodium falciparum Carbonic Anhydrase: Towards Artesunate Hybrid Compounds with Dual Mechanism of Action 193
CARBAMOSELENOYL DERIVATIVES AS ANTI-INFECTIVE AGENTS 192
A computer-assisted discovery of novel potential anti-obesity compounds as selective carbonic anhydrase VA inhibitors 192
Direct and Straightforward access to substituted alkyl selenols as novel carbonic anhydrase inhibitors 190
Targeting Tumor Hypoxia: Suppression of Breast TumorGrowth and Metastasis by Novel Carbonic Anhydrase IX Inhibitors 190
N-aryl-N’-ureido-O-sulfamates: Potent and selective inhibitors of the human Carbonic Anhydrase VII isoform with neuropathic pain relieving properties 189
Hypoxia induced CA9 inhibitory targeting by two different sulfonamide derivatives including acetazolamide in human glioblastoma. 187
Carbonic anhydrases and their functional differences in human and mouse sperm physiology 187
Escinosome thermosensitive gel optimizes efficacy of CAI-CORM in a rat model of rheumatoid arthritis 185
Acyl selenoureido benzensulfonamides show potent inhibitory activity against carbonic anhydrases from the pathogenic bacterium Vibrio cholerae 184
The role of carbonic anhydrases in extinction of contextual fear memory 184
Bioisosteric Development of Multitarget Nonsteroidal Anti-Inflammatory Drug-Carbonic Anhydrases Inhibitor Hybrids for the Management of Rheumatoid Arthritis 184
More effective dithiocarbamate derivatives inhibiting carbonic anhydrases, generated by QSAR and computational design. 184
Development of a new lc-ms/ms screening method for detection of 120 nps and 43 drugs in blood 184
Carbonic anhydrase inhibition for the management of cerebral ischemia: in vivo evaluation of sulfonamide and coumarin inhibitors 180
Specific inhibition of carbonic anhydrase IX activity enhances the in vivo therapeutic effect of tumor irradiation. 179
A non-catalytic function of carbonic anhydrase IX contributes to the glycolytic phenotype and pH regulation in human breast cancer cells 179
Synthesis of a new series of dithiocarbamates with effective human carbonic anhydrase inhibitory activity and antiglaucoma action 179
Structural insights on carbonic anhydrase inhibitory action, isoform selectivity, and potency of sulfonamides and coumarins incorporating arylsulfonylureido groups. 178
2-Mercaptobenzoxazoles: a class of carbonic anhydrase inhibitors with a novel binding mode to the enzyme active site 178
Benzenesulfonamide decorated dihydropyrimidin(thi)ones: carbonic anhydrase profiling and antiproliferative activity 177
Design and Synthesis of Novel Nonsteroidal Anti-Inflammatory Drugs and Carbonic Anhydrase Inhibitors Hybrids (NSAIDs-CAIs) for the Treatment of Rheumatoid Arthritis 177
Metalloenzyme inhibitors for the treatment of Gram-negative bacterial infections: a patent review (2009 - 2012). 176
Azidothymidine "clicked" into 1,2,3-Triazoles: First Report on Carbonic Anhydrase-Telomerase Dual-Hybrid Inhibitors 176
Dithiocarbamates strongly inhibit the β-class carbonic anhydrases from Mycobacterium tuberculosis. 175
An Update on Natural Products with Carbonic Anhydrase Inhibitory Activity 175
Inhibition of the β-carbonic anhydrase from the dandruff-producing fungus Malassezia globosa with monothiocarbamates 175
Development of 3-(4-aminosulphonyl)-phenyl-2-mercapto-3H-quinazolin-4-ones as inhibitors of carbonic anhydrase isoforms involved in tumorigenesis and glaucoma 175
Inhibition of β-carbonic anhydrases with ureido-substituted benzenesulfonamides. 173
Glycomimetic Based Approach toward Selective Carbonic Anhydrase Inhibitors 173
Synthesis 4-[2-(2-mercapto-4-oxo-4H-quinazolin-3-yl)-ethyl]-benzenesulfonamides with subnanomolar carbonic anhydrase II and XII inhibitory properties 173
Totale 21.496
Categoria #
all - tutte 131.804
article - articoli 0
book - libri 0
conference - conferenze 0
curatela - curatele 0
other - altro 0
patent - brevetti 0
selected - selezionate 0
volume - volumi 0
Totale 131.804


Totale Lug Ago Sett Ott Nov Dic Gen Feb Mar Apr Mag Giu
2021/20221.405 0 0 169 52 46 150 56 125 83 109 172 443
2022/20233.419 441 946 138 118 182 557 405 125 315 20 102 70
2023/20241.485 34 127 286 140 90 107 53 345 38 126 96 43
2024/202510.172 322 1.020 612 1.342 3.116 1.148 316 414 555 305 480 542
2025/202616.534 1.296 2.357 1.748 2.021 1.422 544 1.624 872 1.063 969 664 1.954
2026/20272.384 635 586 1.163 0 0 0 0 0 0 0 0 0
Totale 47.187