CARTA, FABRIZIO
 Distribuzione geografica
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Continente #
NA - Nord America 10.868
EU - Europa 5.762
AS - Asia 1.020
AF - Africa 13
SA - Sud America 6
Continente sconosciuto - Info sul continente non disponibili 4
Totale 17.673
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Nazione #
US - Stati Uniti d'America 10.845
PL - Polonia 2.946
IT - Italia 902
IE - Irlanda 865
HK - Hong Kong 489
SE - Svezia 485
CN - Cina 206
RU - Federazione Russa 113
GB - Regno Unito 102
FI - Finlandia 100
VN - Vietnam 85
IN - India 71
DE - Germania 68
JO - Giordania 66
ES - Italia 58
SG - Singapore 45
CH - Svizzera 30
TR - Turchia 30
UA - Ucraina 30
CA - Canada 22
BE - Belgio 17
NL - Olanda 15
RO - Romania 11
FR - Francia 10
EG - Egitto 8
JP - Giappone 6
BG - Bulgaria 5
PK - Pakistan 5
BR - Brasile 4
EU - Europa 4
SA - Arabia Saudita 4
AR - Argentina 2
CZ - Repubblica Ceca 2
ET - Etiopia 2
GH - Ghana 2
ID - Indonesia 2
KR - Corea 2
TJ - Tagikistan 2
AF - Afghanistan, Repubblica islamica di 1
BY - Bielorussia 1
DK - Danimarca 1
GE - Georgia 1
KG - Kirghizistan 1
MN - Mongolia 1
MX - Messico 1
PH - Filippine 1
SK - Slovacchia (Repubblica Slovacca) 1
TH - Thailandia 1
UZ - Uzbekistan 1
ZA - Sudafrica 1
Totale 17.673
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Città #
Warsaw 2.946
Fairfield 2.313
Woodbridge 1.050
Ashburn 983
Seattle 949
Cambridge 867
Dublin 849
Houston 841
Wilmington 724
Chandler 504
Altamura 417
Lawrence 390
Ann Arbor 374
Hong Kong 295
Princeton 270
Florence 184
Beijing 130
Boston 129
Medford 123
San Diego 100
Moscow 99
Boardman 86
Dong Ket 79
Barcelona 52
Norwalk 42
Gavirate 39
Falls Church 37
Jacksonville 36
Rome 33
London 32
Bern 30
Hillsboro 28
Shanghai 28
Phoenix 25
Andover 24
Buffalo 22
Izmir 21
New York 20
Dearborn 18
Toronto 18
Brussels 17
Los Angeles 17
Redmond 13
Scandicci 11
Siena 11
Castelliri 10
Tappahannock 10
West Jordan 10
Detroit 9
Düsseldorf 9
Laurel 9
Redwood City 9
Singapore 9
Washington 9
Misano Adriatico 8
New Delhi 7
Shenzhen 7
Chengdu 6
Corato 6
Dummerstorf 6
Prato 6
Pune 6
Timisoara 6
Delhi 5
Esslingen am Neckar 5
Fuzhou 5
Guangzhou 5
Kilburn 5
Milan 5
Nanjing 5
Philadelphia 5
Renton 5
Sacramento 5
Sofia 5
Yaroslavl 5
Chicago 4
Chiswick 4
Grevenbroich 4
Hyderabad 4
Killbuck 4
Padova 4
Prescot 4
Turin 4
Wuhan 4
Acton 3
Araraquara 3
Chieti 3
Dhubri 3
Groningen 3
Jinan 3
Lahore 3
Lappeenranta 3
Livorno 3
Messina 3
Mountain View 3
New Bedfont 3
Paris 3
Portici 3
Serra 3
Seville 3
Totale 15.562
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Nome #
Polyamines inhibit carbonic anhydrases by anchoring to the zinc-coordinated water molecule. 238
Ureido-Substituted Benzenesulfonamides Potently Inhibit Carbonic Anhydrase IX and Show Antimetastatic Activity in a Model of Breast Cancer Metastasis 216
Dithiocarbamates: a new class of carbonic anhydrase inhibitors. Crystallographic and kinetic investigations. 212
Assembly comprising an absorber of near infrared (nir) light covalently linked to an inhibitor of carbonic anhydrase 208
CO2 and HCO3- Permeability of the Rat Liver Mitochondrial Membrane 207
Mono-/dihydroxybenzoic acid esters and phenol pyridinium derivatives as inhibitors of the mammalian carbonic anhydrase isoforms I, II, VII, IX, XII and XIV. 186
Synthesis of new 3-(2-mercapto-4-oxo-4H-quinazolin-3-yl)-benzenesulfonamides with strong inhibition properties against the tumor associated carbonic anhydrases IX and XII 150
The carbonic anhydrase IX inhibitor SLC-0111 sensitises cancer cells to conventional chemotherapy 148
Design, synthesis, molecular modeling, and anti-HIV-1 integrase activity of a series of photoactivatable diketo acid-containing inhibitors as affinity probes 148
Dithiocarbamates with potent inhibitory activity against the Saccharomyces cerevisiae β-carbonic anhydrase 145
Heterocoumarins Are Selective Carbonic Anhydrase IX and XII Inhibitors with Cytotoxic Effects against Cancer Cells Lines 142
7-Amino-3,4-dihydro-1H-quinolin-2-one, a compound similar to the substituted coumarins, inhibits α-carbonic anhydrases without hydrolysis of the lactam ring. 141
Novel small molecule protein arginine deiminase 4 (PAD4) inhibitors 141
Next-generation polyamine human carbonic anhydrase inhibitors 139
Structural effect of phenyl ring compared to thiadiazole based adamantyl-sulfonamides on carbonic anhydrase inhibition 139
Design, Synthesis, and X-ray of Selenides as New Class of Agents for Prevention of Diabetic Cerebrovascular Pathology 137
Next-generation dithiocarbamate carbonic anhydrase inhibitors 137
Structural Investigation of 3,5-Disubstituted Isoxazoles by1H-Nuclear Magnetic Resonance 136
Diuretics with carbonic anhydrase inhibitory action: A patent and literature review (2005-2013) 135
Design and synthesis of novel dihydroxyindole-2-carboxylic acids as HIV-1 integrase inhibitors 133
Lead Development of Thiazolylsulfonamides with Carbonic Anhydrase Inhibitory Action 132
Blocking HIF signaling via novel inhibitors of CA9 and APE1/Ref-1 dramatically affects pancreatic cancer cell survival 132
Searching for intermediates in Prins cyclisations: The 2-oxa-5-adamantyl carbocation 131
Exploring QSARs of some benzenesulfonamides incorporating cyanoacrylamide moieties as a carbonic anhydrase inhibitors (specifically against tumor-associated isoforms IX and XII) 131
Structural modulation of the biological activity of gold nanoparticles functionalized with a carbonic anhydrase inhibitor. 128
Discovery of 4-Hydroxy-3-(3-(phenylureido)benzenesulfonamides as SLC-0111 Analogues for the Treatment of Hypoxic Tumors Overexpressing Carbonic Anhydrase IX 125
A New Kid on the Block? Carbonic Anhydrases as Possible New Targets in Alzheimer's Disease 122
A potentiated cooperation of carbonic anhydrase IX and histone deacetylase inhibitors against cancer 118
Antiglaucoma carbonic anhydrase inhibitors: a patent review. 117
In vitro inhibition of Mycobacterium tuberculosis β-carbonic anhydrase 3 with Mono- and dithiocarbamates and evaluation of their toxicity using zebrafish developing embryos 114
Deciphering the Mechanism of Human Carbonic Anhydrases Inhibition with Sulfocoumarins: Computational and Experimental Studies 113
BRAIN CARBONIC ANHYDRASES INHIBITION IMPAIRS FEAR MEMORY EXTINCTION IN RATS 113
Antiobesity carbonic anhydrase inhibitors: a literature and patent review. 113
Discovery of New Selenoureido Analogues of 4-(4-Fluorophenylureido)benzenesulfonamide as Carbonic Anhydrase Inhibitors 112
Mycobacterium tuberculosisβ-Carbonic Anhydrases: Novel Targets for Developing Antituberculosis Drugs 112
Cyclodextrin complexation highly enhances efficacy of arylsulfonylureido benzenesulfonamide carbonic anhydrase inhibitors as a topical antiglaucoma agents 112
Evaluation of Thio- and Seleno-Acetamides Bearing Benzenesulfonamide as Inhibitor of Carbonic Anhydrases from Different Pathogenic Bacteria 110
Design and Synthesis of Novel Nonsteroidal Anti-Inflammatory Drugs and Carbonic Anhydrase Inhibitors Hybrids (NSAIDs-CAIs) for the Treatment of Rheumatoid Arthritis 110
Polyamines and α-carbonic anhydrases 108
Synthesis of aminocyanopyrazoles via a multi-component reaction and anti-carbonic anhydrase inhibitory activity of their sulfamide derivatives against cytosolic and transmembrane isoforms. 107
Peptidomimetics as protein arginine deiminase 4 (PAD4) inhibitors. 107
A class of 4-Sulfamoylphenyl-ω-aminoalkyl ethers with effective carbonic anhydrase inhibitory action and antiglaucoma effects. 106
Design of novel bioisosteres of β-diketo acid inhibitors of HIV-1 integrase 106
Novel sulfamide-containing compounds as selective carbonic anhydrase i inhibitors 106
4-Arylbenzenesulfonamides as Human Carbonic Anhydrase Inhibitors (hCAIs): Synthesis by Pd Nanocatalyst-Mediated Suzuki-Miyaura Reaction, Enzyme Inhibition, and X-ray Crystallographic Studies 106
From ligand to complexes. Part 2. Remarks on human immunodeficiency virus type 1 integrase inhibition by β-diketo acid metal complexes 106
7-Substituted-sulfocoumarins are isoform-selective, potent carbonic anhydrase II inhibitors. 105
Structural insights on carbonic anhydrase inhibitory action, isoform selectivity, and potency of sulfonamides and coumarins incorporating arylsulfonylureido groups. 105
[(Cp-R)M(CO)(3) ] (M=Re or (99m) Tc) Arylsulfonamide, Arylsulfamide, and Arylsulfamate Conjugates for Selective Targeting of Human Carbonic Anhydrase IX. 104
Carbonic anhydrase activation enhances object recognition memory in mice through phosphorylation of the extracellular signal-regulated kinase in the cortex and the hippocampus. 104
5- and 6-membered (thio)lactones are prodrug type carbonic anhydrase inhibitors. 103
Specific inhibition of carbonic anhydrase IX activity enhances the in vivo therapeutic effect of tumor irradiation. 103
Dithiocarbamates strongly inhibit the β-class carbonic anhydrases from Mycobacterium tuberculosis. 103
Metalloenzyme inhibitors for the treatment of Gram-negative bacterial infections: a patent review (2009 - 2012). 103
Overexpression of the transmembrane carbonic anhydrase isoforms IX and XII in the inflamed synovium 103
Carbonic anhydrase IX inhibition affects viability of cancer cells adapted to extracellular acidosis 103
Plasmonic Particles that Hit Hypoxic Cells 102
Combining the tail and the ring approaches for obtaining potent and isoform-selective carbonic anhydrase inhibitors: solution and X-ray crystallographic studies. 101
Synthesis and evaluation of carbonic anhydrase inhibitors with carbon monoxide releasing properties for the management of rheumatoid arthritis 101
Discovery of β-Adrenergic Receptors Blocker-Carbonic Anhydrase Inhibitor Hybrids for Multitargeted Antiglaucoma Therapy 101
Advances in New Psychoactive Substances Identification: The U.R.I.To.N Consortium 101
Carbonic anhydrases and their functional differences in human and mouse sperm physiology 101
Design and synthesis of novel indole β-diketo acid derivatives as HIV-1 integrase inhibitors 100
6-Substituted 1,2-benzoxathiine-2,2-dioxides are isoform-selective inhibitors of human carbonic anhydrases IX, XII and VA. 99
Hypoxia induced CA9 inhibitory targeting by two different sulfonamide derivatives including acetazolamide in human glioblastoma. 99
Synthesis of a new series of dithiocarbamates with effective human carbonic anhydrase inhibitory activity and antiglaucoma action 98
Virtual screening-driven identification of human carbonic anhydrase inhibitors incorporating an original, new pharmacophore. 97
Inhibition of β-carbonic anhydrases with ureido-substituted benzenesulfonamides. 97
More effective dithiocarbamate derivatives inhibiting carbonic anhydrases, generated by QSAR and computational design. 96
N-aryl-N’-ureido-O-sulfamates: Potent and selective inhibitors of the human Carbonic Anhydrase VII isoform with neuropathic pain relieving properties 95
Click-tailed coumarins with potent and selective inhibitory action against the tumor-associated carbonic anhydrases IX and XII 94
Carbonic anhydrase inhibitors: inhibition of cytosolic carbonic anhydrase isozymes II and VII with simple aromatic sulfonamides and some azo dyes. 93
Pain relieving effect of-NSAIDS-CAIs hybrid molecules: Systemic and intra-articular treatments against rheumatoid arthritis 93
New natural product carbonic anhydrase inhibitors incorporating phenol moieties 92
The anticonvulsant sulfamide JNJ-26990990 and its: S, S -dioxide analog strongly inhibit carbonic anhydrases: Solution and X-ray crystallographic studies 92
Inhibition of the β-carbonic anhydrase from the dandruff-producing fungus Malassezia globosa with monothiocarbamates 92
Carbonic anhydrase inhibitors. Diazenylbenzenesulfonamides are potent and selective inhibitors of the tumor-associated isozymes IX and XII over the cytosolic isoforms I and II. 92
Polypharmacology of sulfonamides: pazopanib, a multitargeted receptor tyrosine kinase inhibitor in clinical use, potently inhibits several mammalian carbonic anhydrases. 92
Development of potent carbonic anhydrase inhibitors incorporating both sulfonamide and sulfamide groups. 91
Furazan and furoxan sulfonamides are strong α-carbonic anhydrase inhibitors and potential antiglaucoma agents. 91
Benzenesulfonamides Incorporating Flexible Triazole Moieties Are Highly Effective Carbonic Anhydrase Inhibitors: Synthesis and Kinetic, Crystallographic, Computational, and Intraocular Pressure Lowering Investigations 91
Selective inhibition of carbonic anhydrase IX over carbonic anhydrase XII in breast cancer cells using benzene sulfonamides: Disconnect between activity and growth inhibition 91
Dithiocarbamates are strong inhibitors of the beta-class fungal carbonic anhydrases from Cryptococcus neoformans, Candida albicans and Candida glabrata. 90
Xanthates and Trithiocarbonates Strongly Inhibit Carbonic Anhydrases and Show Antiglaucoma Effects in Vivo. 90
Acyl selenoureido benzensulfonamides show potent inhibitory activity against carbonic anhydrases from the pathogenic bacterium Vibrio cholerae 90
Carbonic anhydrase IX from cancer-associated fibroblasts drives epithelial-mesenchymal transition in prostate carcinoma cells 90
6-substituted sulfocoumarins are selective carbonic anhdydrase IX and XII Inhibitors with significant cytotoxicity against colorectal cancer cells 90
Secondary and tertiary sulfonamides: a patent review (2008 - 2012). 88
7-Aryl-triazolyl-substituted sulfocoumarins are potent, selective inhibitors of the tumor-associated carbonic anhydrase IX and XII 88
Carbonic anhydrase inhibitors as novel drugs against mycobacterial β-carbonic anhydrases: An update on in vitro and in vivo studies 87
Sulfonamides and their isosters as carbonic anhydrase inhibitors. 86
Phenols and polyphenols as Carbonic anhydrase inhibitors 86
Polypharmacology of epacadostat: A potent and selective inhibitor of the tumor associated carbonic anhydrases IX and XII 86
Novel coumarins and 2-thioxo-coumarins as inhibitors of the tumor-associated carbonic anhydrases IX and XII. 85
Antimetastatic Effect of Sulfamate Carbonic Anhydrase IX Inhibitors in Breast Carcinoma Xenografts. 85
Multivalent Carbonic Anhydrases Inhibitors 85
A class of sulfonamide carbonic anhydrase inhibitors with neuropathic pain modulating effects 85
Carbonic anhydrase inhibitors: Synthesis and inhibition of the human carbonic anhydrase isoforms I, II, IX and XII with benzene sulfonamides incorporating 4- and 3-nitrophthalimide moieties 85
Poly(amidoamine) dendrimers show carbonic anhydrase inhibitory activity against α-, β-, γ- and η-class enzymes 83
Benzylaminoethyureido-Tailed Benzenesulfonamides: Design, Synthesis, Kinetic and X-ray Investigations on Human Carbonic Anhydrases 83
Totale 11.325
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Categoria #
all - tutte 53.235
article - articoli 0
book - libri 0
conference - conferenze 0
curatela - curatele 0
other - altro 0
patent - brevetti 0
selected - selezionate 0
volume - volumi 0
Totale 53.235
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Totale Lug Ago Sett Ott Nov Dic Gen Feb Mar Apr Mag Giu
2018/20191.867 0 0 0 0 0 0 0 0 0 391 803 673
2019/20205.135 373 343 201 403 638 580 618 625 564 336 346 108
2020/20213.232 230 360 109 283 376 293 150 220 323 490 198 200
2021/20221.637 55 171 169 52 46 151 56 126 83 111 172 445
2022/20233.427 442 950 138 118 182 559 406 125 315 20 102 70
2023/20241.334 34 127 286 140 90 107 53 346 39 112 0 0
Totale 17.976