ROMANELLI, MARIA NOVELLA
 Distribuzione geografica
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Continente #
NA - Nord America 21.721
EU - Europa 13.900
AS - Asia 8.755
SA - Sud America 1.037
Continente sconosciuto - Info sul continente non disponibili 347
AF - Africa 226
OC - Oceania 155
Totale 46.141
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Nazione #
US - Stati Uniti d'America 21.250
RU - Federazione Russa 3.893
IT - Italia 2.881
PL - Polonia 2.511
SG - Singapore 2.473
CN - Cina 2.023
HK - Hong Kong 1.362
IE - Irlanda 1.012
VN - Vietnam 980
SE - Svezia 951
BR - Brasile 804
KR - Corea 762
DE - Germania 651
UA - Ucraina 456
FI - Finlandia 455
FR - Francia 389
GB - Regno Unito 324
IN - India 312
CA - Canada 299
JP - Giappone 152
AU - Australia 149
BD - Bangladesh 142
TR - Turchia 88
ID - Indonesia 86
JO - Giordania 81
NL - Olanda 80
MX - Messico 71
AR - Argentina 69
CH - Svizzera 67
IQ - Iraq 59
ES - Italia 53
CI - Costa d'Avorio 49
BE - Belgio 45
CO - Colombia 41
ZA - Sudafrica 40
PK - Pakistan 35
NG - Nigeria 30
SC - Seychelles 30
AT - Austria 29
EC - Ecuador 28
VE - Venezuela 28
CL - Cile 27
UZ - Uzbekistan 19
JM - Giamaica 18
PH - Filippine 18
SA - Arabia Saudita 18
MA - Marocco 16
MY - Malesia 16
TT - Trinidad e Tobago 16
AZ - Azerbaigian 15
RO - Romania 15
IL - Israele 14
CR - Costa Rica 13
CZ - Repubblica Ceca 13
PE - Perù 13
PY - Paraguay 13
TW - Taiwan 12
DZ - Algeria 11
KE - Kenya 11
LT - Lituania 11
TH - Thailandia 11
EG - Egitto 10
KZ - Kazakistan 9
NP - Nepal 9
PR - Porto Rico 9
PT - Portogallo 9
AE - Emirati Arabi Uniti 8
GT - Guatemala 8
HN - Honduras 8
LB - Libano 8
TN - Tunisia 8
NI - Nicaragua 7
HU - Ungheria 6
KG - Kirghizistan 6
NZ - Nuova Zelanda 6
SK - Slovacchia (Repubblica Slovacca) 6
BG - Bulgaria 5
BJ - Benin 5
BO - Bolivia 5
DK - Danimarca 5
IR - Iran 5
SN - Senegal 5
AL - Albania 4
AM - Armenia 4
BH - Bahrain 4
HR - Croazia 4
MO - Macao, regione amministrativa speciale della Cina 4
NO - Norvegia 4
OM - Oman 4
SI - Slovenia 4
UY - Uruguay 4
BS - Bahamas 3
BY - Bielorussia 3
CY - Cipro 3
DO - Repubblica Dominicana 3
ET - Etiopia 3
EU - Europa 3
GE - Georgia 3
GR - Grecia 3
PS - Palestinian Territory 3
Totale 45.750
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Città #
Santa Clara 3.904
Ashburn 2.540
Warsaw 2.493
Singapore 1.763
Fairfield 1.389
Hong Kong 1.143
Chandler 1.141
Dublin 1.002
San Jose 803
Seoul 710
Jacksonville 668
Woodbridge 645
Cambridge 574
Seattle 563
Houston 562
Milan 490
Wilmington 484
Council Bluffs 450
Beijing 417
Hefei 410
Los Angeles 378
Buffalo 376
Ann Arbor 312
The Dalles 295
Princeton 260
Rome 242
Altamura 237
Ho Chi Minh City 226
Florence 223
Munich 219
Boston 212
Lauterbourg 211
Lawrence 206
Hanoi 203
Dong Ket 199
Dallas 182
Mumbai 173
New York 155
Helsinki 149
Moscow 147
Chicago 144
Tokyo 144
Melbourne 142
Phoenix 132
Boardman 129
Medford 105
San Diego 94
Kent 91
Shanghai 91
Washington 87
Paris 77
São Paulo 71
Naples 67
Turku 65
Turin 60
Toronto 58
Bern 57
Bologna 55
Jakarta 54
Philadelphia 53
Norwalk 51
Orem 51
London 50
Abidjan 49
Guangzhou 48
Montreal 48
Frankfurt am Main 46
Falls Church 44
Clifton 43
Brussels 41
Columbus 40
Seongnam 40
Verona 39
Denver 38
Figino 38
Bari 37
Haiphong 37
Redondo Beach 37
Hillsboro 36
Izmir 36
Atlanta 35
West Jordan 35
Lappeenranta 34
Genoa 32
Brooklyn 31
Da Nang 31
Tianjin 30
Abuja 29
Chennai 29
Frankfurt Am Main 27
San Francisco 26
Brasília 24
Nuremberg 23
Palermo 23
Andover 22
Johannesburg 22
Amsterdam 21
Miano 21
Venice 21
Brescia 20
Totale 29.917
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Nome #
DM235 (sunifiram): a novel nootropic with potential as a cognitive enhancer 720
Molecular simplification of 1,4-diazabicyclo[4.3.0]nonan-9-ones gives piperazine derivatives that maintain high nootropic activity 445
4-Aminopiperidine derivatives as a new class of potent cognition enhancing drugs 432
Design, synthesis and binding affinity of new nicotinic ligands 358
Effectiveness of the histone deacetylase inhibitor (S)-2 against LNCaP and PC3 human prostate cancer cells 332
HDAC-inhibitor (S)-8 disrupts HDAC6-PP1 complex prompting A375 melanoma cell growth arrest and apoptosis. 332
New isoform-selective HCN blockers 329
Pharmacological characterization of DM232 (unifiram) and DM235 (sunifiram), new potent cognition-enhancers 322
Design, synthesis and preliminary pharmacological evaluation of 1,4-diazabicyclo[4.3.0]nonan-9-ones as a new class of highly potent nootropic drugs. 320
New Histamine-Related Five-Membered N-Heterocycle Derivatives as Carbonic Anhydrase I Activators 314
PHARMACOLOGICAL CHARACTERIZATION OF THE NOVEL ACH RELEASER A-TROPANYL 2-(4-BROMOPHENYL)PROPIONATE (PG-9). 313
Presynaptic Cholinergic Modulators as Potent Cognition Enhancers and Analgesic Drugs. 2. 2-Phenoxy-, 2-(phenylthio)- and 2-(phenylamino)alkanoic Acid Esters 308
DESIGN, SYNTHESIS AND PRELIMINARY PHARMACOLOGICAL EVALUATION OF RIGID ANALOGUES OF THE NICOTINIC AGONIST 1,1-DIMETHYL-4-PHENYLPIPERAZINIUM IODIDE (DMPP) 303
Selective HCN1 block as a strategy to control oxaliplatin-induced neuropathy 301
2-Benzylpiperazine: a new scaffold for potent human Carbonic Anhydrase inhibitors. Synthesis, enzyme inhibition, enantioselectivity, computational and crystallographic studies and in vivo activity for a new class of intraocular pressure lowering agents. 297
ANTINOCICEPTION INDUCED BY SM32 DEPENDS ON CENTRAL CHOLINERGIC MECHANISM 295
The new low-toxic histone deacetylase inhibitor S-(2) induces apoptosis in various acute myeloid leukemia cells 293
Design, synthesis and biological evaluation of stereo- and regioisomers of amino aryl esters as multidrug resistance (MDR) reversers 284
STEREOSELECTIVE INCREASE IN CHOLINERGIC TRANSMISSION BY R-(+)- HYOSCYAMINE 280
Amino acids as building blocks for carbonic anhydrase inhibitors 280
A potentiated cooperation of carbonic anhydrase IX and histone deacetylase inhibitors against cancer 275
THE FROZEN ANALOG APPROACH IN MEDICINAL CHEMISTRY 269
Two types of interneurons in the mouse lateral geniculate nucleus are characterized by different h-current density 265
Recent advances in the search of BCRP- and dual P-gp/BCRP-based multidrug resistance modulators 265
1,3-oxathiolane muscarinic ligands modified at the cationic head. 264
1,3-MIGRATION OF CHLORIDE AND AZIDE SUBSTITUENTS WITHIN ORGANOSILICON CATIONS, AND ANCHIMERIC ASSISTANCE BY THE AZIDO GROUP 263
Modulation of the spacer in N,N-bis(alkanol)amine aryl ester heterodimers led to the discovery of a series of highly potent P-glycoprotein-based multidrug-resistance (MDR) modulators 261
New Rigid Nicotine Analogues, Carrying a Norbornane Moiety, Are Potent Agonists of α7 and α3∗ Nicotinic Receptors 257
Design, synthesis and preliminary biological evaluation of new isoform-selective f-current blockers. 255
Binding Profiles of a Series of 2-Arylpropionic Acid Esters on Cloned Human Muscarinic Receptors Subtypes (m1-m5) and Their Relationship to Nootropic Activity 252
The hyperpolarization-activated HCN4 channel is Important for proper maintenance of oscillatory activity in the thalamocortical system 252
Arylamino Esters as P-Glycoprotein Modulators: SAR Studies to Establish Requirements for Potency and Selectivity 250
6,7-Dimethoxy-2-phenethyl-1,2,3,4-tetrahydroisoquinoline amides and corresponding ester isosteres as multidrug resistance reversers 245
2-(2-Hydroxyethyl)piperazine derivatives as potent human carbonic anhydrase inhibitors: Synthesis, enzyme inhibition, computational studies and antiglaucoma activity 244
Multidrug resistance (MDR) reversers: High activity and efficacy in a series of asymmetrical N,N-bis(alkanol)amine aryl esters 240
Selective Blockade of HCN1/HCN2 Channels as a Potential Pharmacological Strategy Against Pain 237
Design and synthesis of new potent N,N-bis(arylalkyl)piperazine derivatives as multidrug resistance (MDR) reversing agents 236
Synthesis and carbonic anhydrase activating properties of a series of 2-amino-imidazolines structurally related to clonidine 236
N,N-bis(cyclohexanol)amine aryl esters: a new class of highly potent Pgp-dependent multidrug resistance (MDR) inhibitors 231
Antagonisti muscarinici a struttura 1,3-ossatiolano-2-pirrolidinica 229
Design, synthesis and preliminary biological evaluation of zatebradine analogues as potential blockers of the hyperpolarization-activated current 227
Design, synthesis and preliminary biological evaluation of new hydroxamate histone deacetylase inhibitors as potential antileukemic agents 226
Central Nicotinic receptors: structure, function, ligands, and therapeutic potential 223
AMPA-receptor activation is involved in the antiamnesic effect of DM 232 (unifiram) and DM 235 (sunifiram). 222
1,4-Diazabicyclo[4.3.0]nonan-9-ones and 1,4-diamidopiperazines as new classes of highly potent nootropic drugs 221
Design, Synthesis, and Preliminary Pharmacological Evaluation of New Quinoline Derivatives as Nicotinic Ligands 220
New structure–activity relationship studies in a series of N,N-bis(cyclohexanol)amine aryl esters as potent reversers of P-glycoprotein-mediated multidrug resistance (MDR) 219
Dual P-glycoprotein and CA XII inhibitors: A new strategy to reverse the P-gp Mediated Multidrug Resistance (MDR) in cancer cells y 219
Analgesic effects of myrrh 217
FURTHER STRUCTURE-ACTIVITY RELATIONSHIPS IN THE SERIES OF TROPANYL ESTERS ENDOWED WITH POTENT ANTINOCICEPTIVE ACTIVITY 216
SYNTHESIS, AFFINITY PROFILE AND FUNCTIONAL ACTIVITY OF MUSCARINIC ANTAGONISTS WITH A 1-METHYL-2-(2,2-ALKYLARYL-1,3-OXATHIOLAN-5-YL)PYRROLIDINE STRUCTURE 216
Design, synthesis and nootropic activity of new analogues of sunifiram and sapunifiram, two potent cognition-enhancers. 215
SEMI-RIGID ANALOGUES OF THE CALCIUM ANTAGONIST VERAPAMIL: A MOLECULAR MODELLING STUDY 214
ISOMERIC N,N-BIS(CYCLOHEXANOL)AMINE ARYL ESTERS: THE DISCOVERY OF A NEW CLASS OF HIGHLY POTENT P-GLYCOPROTEIN (PGP)-DEPENDENT MULTIDRUG RESISTANCE (MDR) INHIBITORS 213
COGNITION-ENHANCING DRUGS IN MILD COGNITIVE IMPAIRMENT (MCI) AND ALZHEIMER'S DISEASE (AD): AN UPDATE[1] 213
Carbonic Anhydrase IV Selective Inhibitors Counteract the Development of Colitis-Associated Visceral Pain in Rats 213
Aminoarylesters as multidrug resistance (MDR) reverting agents endowed with high potency and efficacy 212
Highly chiral muscarinic ligands: the discovery of (2S,2'R,3'S,5'R)-1-methyl-2-(2-methyl-1,3-oxathiolan-5-yl)pyrrolidine 3-sulfoxide methyl iodide, a potent, functionally selective, M2 partial agonist. 212
Designing selective modulators for the nicotinic receptor subtypes: challenges and opportunities 212
CHARACTERIZATION OF THE ACTION ON CENTRAL OPIOID RECEPTORS OF FURANOEUDESMA-1,3-DIENE, A SESQUITERPENE EXTRACTED FROM MYRRH 211
2- or 3-Substituted piperazines as nootropic agents: carbethoxy and hydroxymethyl analogues of the cognition-enhancer DM235 208
Investigation of piperazines as human carbonic anhydrase I, II, IV and VII activators 208
Carbachol dimers as homobivalent modulators of muscarinic receptors 208
Design, synthesis and preliminary evaluation of a series of histone deacetylase inhibitors carrying a benzodiazepine ring 205
(E)-3-Furan-2-yl- N- p-tolyl-acrylamide and its Derivative DM489 Decrease Neuropathic Pain in Mice Predominantly by α7 Nicotinic Acetylcholine Receptor Potentiation 205
Recent advances in the discovery of Nicotinic acetylcholine receptor allosteric modulators 204
ANALGESIC, ANTIMUSCARINIC ACTIVITY AND ENANTIOSELECTIVITY OF THE FOUR ISOMERS OF 3-QUINUCLIDINYL TROPATE AS COMPARED WITH THE ENANTIOMERS OF HYOSCYAMINE 203
Synthesis and Enantioselectivity of the Enantiomers of PG9 and SM21, New Potent Analgesic and Cognition-Enhancing Drugs 201
Design and synthesis of aminoester heterodimers containing flavone or chromone moieties as modulators of P-glycoprotein-based multidrug resistance (MDR) 201
Synthesis and Cholinergic Affinity of Diastereomeric and Enantiomeric Isomers of 1-Methyl-2-(2-methyl-1,3-dioxolan-4-yl)-pyrrolidine, 1-Methyl-2-(2-methyl-1,3-oxathiolan-5-yl)pyrrolidine and of Their Iodomethylates 198
1,4-Diazabicyclo[4.3.0]nonan-9-ones as a new class of highly potent nootropic drugs 196
Design, synthesis and preliminary pharmacological evaluation of new piperidine and piperazine derivatives as cognition-enhancers 195
New phenylalkylamines as isoform selective HCN-Channels blockers 195
Design, synthesis and pharmacological evaluation of some frozen-analogues of DMPP 195
New dual P-Glycoprotein (P-gp) and human carbonic anhydrase XII (hCA XII) inhibitors as Multidrug Resistance (MDR) reversers in cancer cells 192
SYNTHESIS AND BIOLOGICAL ACTIVITY OF A SERIES OF ARYL TROPANYL ESTERS AND AMIDES CHEMICALLY RELATED TO 1H-INDOLE-3-CARBOXYLIC ACID ENDO 8-METHYL-8-AZABICYCLO[3.2.1]OCT-3-YL ESTER 191
Ibogalogs decrease neuropathic pain in mice through a mechanism involving crosstalk between 5-HT2A and mGlu2 receptors 190
Structure-affinity relationships of a unique nicotinic ligand: N1-dimethyl-N4-phenylpiperazinium iodide (DMPP) 189
GRIND-derived pharmacophore model for a series of α-tropanyl derivative ligands of the sigma-2 receptor 189
Chiral synthesis and pharmacological evaluation of the enantiomers of SM32, a new analgesic and cognition-enhancing agent. 188
N-alkanol-N-cyclohexanol amine aryl esters: Multidrug resistance (MDR) reversing agents with high potency and efficacy 188
Piperazines as nootropic agents: New derivatives of the potent cognition-enhancer DM235 carrying hydrophilic substituents 188
"Synthesis and binding properties of photoactivable Biotin-conjugated verapamil derivatives for the study of P-170 glycoprotein" 187
EC18 as a Tool To Understand the Role of HCN4 Channels in Mediating Hyperpolarization-Activated Current in Tissues 187
GRID INDEPENDENT DESCRIPTORS (GRIND) IN THE STUDY OF THE S-RECEPTOR SUBTYPE SELECTIVITY. 186
Design of novel nicotinic ligands through 3D database searching 186
Muscarinic antagonists with multiple stereocenters: synthesis, affinity profile and functional activity of isomeric 1-methyl-2-(2,2-alkylaryl-1,3-oxathiolan-5-yl)pyrrolidine sulfoxide derivatives 186
SYNTHESIS, CHARACTERIZATION AND PHARMACOLOGICAL PROFILE OF TROPICAMIDE ENANTIOMERS 185
P-glycoprotein and carbonic anhydrases hybrid inhibitors: a new strategy to reverse multidrug resistance (MDR) in cancer cells 185
The psychoplastogens ibogaminalog and ibogainalog induce antidepressant-like activity in naïve and depressed mice by mechanisms involving 5-HT2A receptor activation and serotonergic transmission 184
Design, synthesis and preliminary pharmacological evaluation of new analogues of DM232 (unifiram) and DM235 (sunifiram) as cognition modulators. 184
Design, synthesis and preliminary pharmacological evaluation of new analogues of DM232 (unifiram) and DM235 (sunifiram) as cognition modulators 183
The novel non-hallucinogenic compound DM506 (3-methyl-1,2,3,4,5,6-hexahydroazepino[4,5-b]indole) induces sedative- and anxiolytic-like activity in mice by a mechanism involving 5-HT2A receptor activation 182
VERAPAMIL ANALOGUES WITH RESTRICTED MOLECULAR FLEXIBILITY: SYNTHESIS AND PHARMACOLOGICAL EVALUATION OF THE FOUR ISOMERS OF ALPHA-[1-[3-[N-[1-[2-(3,4-DIMETHOXYPHENYL)ETHYL]]-N-METHYLAMINO]CYCLOHEXYL]]-ALPHA-ISOPROPYL-3,4-DIMETHOXYBENZENEACETONITRILE 182
Inhibition of P-glycoprotein-mediated Multidrug Resistance (MDR) by N,N-bis(cyclohexanol)amine aryl esters: further restriction of molecular flexibility maintains high potency and efficacy 181
Attività analgesica e antimuscarinica ed enantioselettività dei quattro isomeri del tropato del 3-chinuclidinolo messe a confronto con gli enantiomeri della iosciamina 181
Carbachol dimers with primary carbamate groups as homobivalent modulators of muscarinic receptors 181
Novel psychoplastogen DM506 reduces cue-induced heroin-seeking and inhibits tonic GABA currents in the Prelimbic Cortex 180
SAR STUDIES ON THE POTENT AND SELECTIVE MUSCARINIC ANTAGONIST 2-ETHYLTHIO-2,2-DIPHENYLACETIC ACID N,N-DIETHYLAMINOETHYL ESTER 180
Design, synthesis and electrophysiological studies of new blockers of HCN channels 180
Totale 23.862
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Categoria #
all - tutte 126.091
article - articoli 0
book - libri 0
conference - conferenze 0
curatela - curatele 0
other - altro 0
patent - brevetti 0
selected - selezionate 0
volume - volumi 0
Totale 126.091
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Totale Lug Ago Sett Ott Nov Dic Gen Feb Mar Apr Mag Giu
2021/20221.348 0 0 0 69 52 66 89 116 57 61 360 478
2022/20234.462 396 757 196 343 340 847 573 269 469 28 143 101
2023/20241.862 68 197 285 88 137 306 74 410 40 87 90 80
2024/202511.370 428 1.168 738 1.538 3.147 1.674 260 732 532 274 444 435
2025/202613.304 1.399 1.790 1.287 878 1.449 586 1.511 639 887 736 396 1.746
2026/20272.937 504 438 1.421 574 0 0 0 0 0 0 0 0
Totale 46.141