ROMANELLI, MARIA NOVELLA
 Distribuzione geografica
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Continente #
NA - Nord America 17.417
EU - Europa 11.861
AS - Asia 6.960
SA - Sud America 901
AF - Africa 171
OC - Oceania 152
Continente sconosciuto - Info sul continente non disponibili 4
Totale 37.466
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Nazione #
US - Stati Uniti d'America 17.243
RU - Federazione Russa 3.890
PL - Polonia 2.505
SG - Singapore 2.092
CN - Cina 1.637
HK - Hong Kong 1.314
IT - Italia 1.284
IE - Irlanda 1.008
SE - Svezia 942
KR - Corea 757
BR - Brasile 740
DE - Germania 612
UA - Ucraina 452
VN - Vietnam 420
FI - Finlandia 415
GB - Regno Unito 272
IN - India 267
FR - Francia 160
AU - Australia 147
CA - Canada 93
ID - Indonesia 79
TR - Turchia 78
JO - Giordania 75
NL - Olanda 67
CH - Svizzera 66
MX - Messico 57
AR - Argentina 55
CI - Costa d'Avorio 48
BE - Belgio 42
ES - Italia 37
JP - Giappone 35
ZA - Sudafrica 32
BD - Bangladesh 31
IQ - Iraq 31
SC - Seychelles 30
AT - Austria 29
PK - Pakistan 27
EC - Ecuador 23
CO - Colombia 21
VE - Venezuela 19
MA - Marocco 16
CL - Cile 15
IL - Israele 14
CZ - Repubblica Ceca 13
SA - Arabia Saudita 12
PH - Filippine 11
PY - Paraguay 11
RO - Romania 11
UZ - Uzbekistan 11
LT - Lituania 10
PE - Perù 10
KE - Kenya 9
AZ - Azerbaigian 8
DZ - Algeria 7
KZ - Kazakistan 7
CR - Costa Rica 6
EG - Egitto 6
LB - Libano 6
NP - Nepal 6
PT - Portogallo 6
SK - Slovacchia (Repubblica Slovacca) 6
BG - Bulgaria 5
BJ - Benin 5
HU - Ungheria 5
IR - Iran 5
NZ - Nuova Zelanda 5
TN - Tunisia 5
AE - Emirati Arabi Uniti 4
DK - Danimarca 4
HR - Croazia 4
JM - Giamaica 4
KG - Kirghizistan 4
MO - Macao, regione amministrativa speciale della Cina 4
SI - Slovenia 4
SN - Senegal 4
TT - Trinidad e Tobago 4
TW - Taiwan 4
AM - Armenia 3
EU - Europa 3
HN - Honduras 3
MY - Malesia 3
BH - Bahrain 2
BO - Bolivia 2
BY - Bielorussia 2
CY - Cipro 2
DO - Repubblica Dominicana 2
ET - Etiopia 2
GE - Georgia 2
GR - Grecia 2
GY - Guiana 2
LV - Lettonia 2
MU - Mauritius 2
NI - Nicaragua 2
OM - Oman 2
PS - Palestinian Territory 2
UY - Uruguay 2
A1 - Anonimo 1
AL - Albania 1
AO - Angola 1
BS - Bahamas 1
Totale 37.449
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Città #
Santa Clara 3.836
Warsaw 2.489
Ashburn 1.537
Singapore 1.410
Fairfield 1.386
Chandler 1.141
Hong Kong 1.111
Dublin 1.000
Seoul 710
Jacksonville 662
Woodbridge 645
Cambridge 573
Houston 550
Seattle 550
Wilmington 483
Hefei 410
Beijing 393
Buffalo 361
Ann Arbor 311
Los Angeles 311
San Jose 293
Princeton 258
Altamura 236
Munich 218
Lawrence 205
Boston 204
The Dalles 203
Dong Ket 199
Florence 187
Mumbai 170
Moscow 146
Dallas 145
Melbourne 142
Boardman 126
Helsinki 111
Medford 104
New York 103
Kent 90
Council Bluffs 88
Milan 84
San Diego 83
Shanghai 77
Ho Chi Minh City 75
Paris 74
Turku 65
São Paulo 63
Hanoi 59
Bern 57
Jakarta 54
Norwalk 50
Abidjan 48
Phoenix 48
Falls Church 44
Clifton 42
London 42
Seongnam 40
Brussels 38
Chicago 37
Redondo Beach 37
Izmir 36
Washington 36
West Jordan 34
Guangzhou 33
Philadelphia 33
Lappeenranta 32
Montreal 32
Tokyo 31
Toronto 30
Rome 29
Frankfurt Am Main 27
Hillsboro 27
Verona 27
Frankfurt am Main 26
Tianjin 26
Andover 22
Vienna 20
Yubileyny 20
Brooklyn 18
Chennai 18
Johannesburg 18
Orem 18
Rio de Janeiro 18
Amsterdam 17
Bengaluru 17
Brasília 17
Nuremberg 17
Denver 16
San Francisco 16
Dearborn 15
Haiphong 15
Stockholm 15
Barcelona 14
Salerno 14
Atlanta 13
Belo Horizonte 13
Münster 13
Amman 12
Ankara 12
Baghdad 12
Lake Geneva 12
Totale 25.085
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Nome #
DM235 (sunifiram): a novel nootropic with potential as a cognitive enhancer 554
Molecular simplification of 1,4-diazabicyclo[4.3.0]nonan-9-ones gives piperazine derivatives that maintain high nootropic activity 377
4-Aminopiperidine derivatives as a new class of potent cognition enhancing drugs 374
Design, synthesis and binding affinity of new nicotinic ligands 332
New isoform-selective HCN blockers 306
HDAC-inhibitor (S)-8 disrupts HDAC6-PP1 complex prompting A375 melanoma cell growth arrest and apoptosis. 302
Effectiveness of the histone deacetylase inhibitor (S)-2 against LNCaP and PC3 human prostate cancer cells 297
Pharmacological characterization of DM232 (unifiram) and DM235 (sunifiram), new potent cognition-enhancers 294
New Histamine-Related Five-Membered N-Heterocycle Derivatives as Carbonic Anhydrase I Activators 280
PHARMACOLOGICAL CHARACTERIZATION OF THE NOVEL ACH RELEASER A-TROPANYL 2-(4-BROMOPHENYL)PROPIONATE (PG-9). 279
Presynaptic Cholinergic Modulators as Potent Cognition Enhancers and Analgesic Drugs. 2. 2-Phenoxy-, 2-(phenylthio)- and 2-(phenylamino)alkanoic Acid Esters 277
Design, synthesis and preliminary pharmacological evaluation of 1,4-diazabicyclo[4.3.0]nonan-9-ones as a new class of highly potent nootropic drugs. 275
Selective HCN1 block as a strategy to control oxaliplatin-induced neuropathy 262
DESIGN, SYNTHESIS AND PRELIMINARY PHARMACOLOGICAL EVALUATION OF RIGID ANALOGUES OF THE NICOTINIC AGONIST 1,1-DIMETHYL-4-PHENYLPIPERAZINIUM IODIDE (DMPP) 260
ANTINOCICEPTION INDUCED BY SM32 DEPENDS ON CENTRAL CHOLINERGIC MECHANISM 255
THE FROZEN ANALOG APPROACH IN MEDICINAL CHEMISTRY 254
Amino acids as building blocks for carbonic anhydrase inhibitors 251
1,3-MIGRATION OF CHLORIDE AND AZIDE SUBSTITUENTS WITHIN ORGANOSILICON CATIONS, AND ANCHIMERIC ASSISTANCE BY THE AZIDO GROUP 242
Two types of interneurons in the mouse lateral geniculate nucleus are characterized by different h-current density 242
The new low-toxic histone deacetylase inhibitor S-(2) induces apoptosis in various acute myeloid leukemia cells 241
STEREOSELECTIVE INCREASE IN CHOLINERGIC TRANSMISSION BY R-(+)- HYOSCYAMINE 238
Design, synthesis and biological evaluation of stereo- and regioisomers of amino aryl esters as multidrug resistance (MDR) reversers 238
2-Benzylpiperazine: a new scaffold for potent human Carbonic Anhydrase inhibitors. Synthesis, enzyme inhibition, enantioselectivity, computational and crystallographic studies and in vivo activity for a new class of intraocular pressure lowering agents. 235
A potentiated cooperation of carbonic anhydrase IX and histone deacetylase inhibitors against cancer 229
The hyperpolarization-activated HCN4 channel is Important for proper maintenance of oscillatory activity in the thalamocortical system 222
Binding Profiles of a Series of 2-Arylpropionic Acid Esters on Cloned Human Muscarinic Receptors Subtypes (m1-m5) and Their Relationship to Nootropic Activity 220
1,3-oxathiolane muscarinic ligands modified at the cationic head. 216
Multidrug resistance (MDR) reversers: High activity and efficacy in a series of asymmetrical N,N-bis(alkanol)amine aryl esters 214
Modulation of the spacer in N,N-bis(alkanol)amine aryl ester heterodimers led to the discovery of a series of highly potent P-glycoprotein-based multidrug-resistance (MDR) modulators 213
Arylamino Esters as P-Glycoprotein Modulators: SAR Studies to Establish Requirements for Potency and Selectivity 212
Design, synthesis and preliminary biological evaluation of new isoform-selective f-current blockers. 211
Recent advances in the search of BCRP- and dual P-gp/BCRP-based multidrug resistance modulators 207
Selective Blockade of HCN1/HCN2 Channels as a Potential Pharmacological Strategy Against Pain 206
N,N-bis(cyclohexanol)amine aryl esters: a new class of highly potent Pgp-dependent multidrug resistance (MDR) inhibitors 201
FURTHER STRUCTURE-ACTIVITY RELATIONSHIPS IN THE SERIES OF TROPANYL ESTERS ENDOWED WITH POTENT ANTINOCICEPTIVE ACTIVITY 196
6,7-Dimethoxy-2-phenethyl-1,2,3,4-tetrahydroisoquinoline amides and corresponding ester isosteres as multidrug resistance reversers 195
Design, synthesis and preliminary biological evaluation of zatebradine analogues as potential blockers of the hyperpolarization-activated current 192
Design, synthesis and preliminary biological evaluation of new hydroxamate histone deacetylase inhibitors as potential antileukemic agents 192
ISOMERIC N,N-BIS(CYCLOHEXANOL)AMINE ARYL ESTERS: THE DISCOVERY OF A NEW CLASS OF HIGHLY POTENT P-GLYCOPROTEIN (PGP)-DEPENDENT MULTIDRUG RESISTANCE (MDR) INHIBITORS 191
Synthesis and carbonic anhydrase activating properties of a series of 2-amino-imidazolines structurally related to clonidine 191
Design, Synthesis, and Preliminary Pharmacological Evaluation of New Quinoline Derivatives as Nicotinic Ligands 191
Central Nicotinic receptors: structure, function, ligands, and therapeutic potential 189
Highly chiral muscarinic ligands: the discovery of (2S,2'R,3'S,5'R)-1-methyl-2-(2-methyl-1,3-oxathiolan-5-yl)pyrrolidine 3-sulfoxide methyl iodide, a potent, functionally selective, M2 partial agonist. 189
SEMI-RIGID ANALOGUES OF THE CALCIUM ANTAGONIST VERAPAMIL: A MOLECULAR MODELLING STUDY 187
Design and synthesis of new potent N,N-bis(arylalkyl)piperazine derivatives as multidrug resistance (MDR) reversing agents 187
Dual P-glycoprotein and CA XII inhibitors: A new strategy to reverse the P-gp Mediated Multidrug Resistance (MDR) in cancer cells y 187
1,4-Diazabicyclo[4.3.0]nonan-9-ones and 1,4-diamidopiperazines as new classes of highly potent nootropic drugs 187
AMPA-receptor activation is involved in the antiamnesic effect of DM 232 (unifiram) and DM 235 (sunifiram). 185
Design, synthesis and nootropic activity of new analogues of sunifiram and sapunifiram, two potent cognition-enhancers. 185
New structure–activity relationship studies in a series of N,N-bis(cyclohexanol)amine aryl esters as potent reversers of P-glycoprotein-mediated multidrug resistance (MDR) 185
CHARACTERIZATION OF THE ACTION ON CENTRAL OPIOID RECEPTORS OF FURANOEUDESMA-1,3-DIENE, A SESQUITERPENE EXTRACTED FROM MYRRH 185
Antagonisti muscarinici a struttura 1,3-ossatiolano-2-pirrolidinica 183
Carbachol dimers as homobivalent modulators of muscarinic receptors 181
SYNTHESIS, AFFINITY PROFILE AND FUNCTIONAL ACTIVITY OF MUSCARINIC ANTAGONISTS WITH A 1-METHYL-2-(2,2-ALKYLARYL-1,3-OXATHIOLAN-5-YL)PYRROLIDINE STRUCTURE 179
Analgesic effects of myrrh 177
2-(2-Hydroxyethyl)piperazine derivatives as potent human carbonic anhydrase inhibitors: Synthesis, enzyme inhibition, computational studies and antiglaucoma activity 177
ANALGESIC, ANTIMUSCARINIC ACTIVITY AND ENANTIOSELECTIVITY OF THE FOUR ISOMERS OF 3-QUINUCLIDINYL TROPATE AS COMPARED WITH THE ENANTIOMERS OF HYOSCYAMINE 176
Synthesis and Enantioselectivity of the Enantiomers of PG9 and SM21, New Potent Analgesic and Cognition-Enhancing Drugs 175
Investigation of piperazines as human carbonic anhydrase I, II, IV and VII activators 174
COGNITION-ENHANCING DRUGS IN MILD COGNITIVE IMPAIRMENT (MCI) AND ALZHEIMER'S DISEASE (AD): AN UPDATE[1] 174
Design and synthesis of aminoester heterodimers containing flavone or chromone moieties as modulators of P-glycoprotein-based multidrug resistance (MDR) 171
Chiral synthesis and pharmacological evaluation of the enantiomers of SM32, a new analgesic and cognition-enhancing agent. 170
GRIND-derived pharmacophore model for a series of α-tropanyl derivative ligands of the sigma-2 receptor 169
Design, synthesis and preliminary evaluation of a series of histone deacetylase inhibitors carrying a benzodiazepine ring 169
Synthesis and Cholinergic Affinity of Diastereomeric and Enantiomeric Isomers of 1-Methyl-2-(2-methyl-1,3-dioxolan-4-yl)-pyrrolidine, 1-Methyl-2-(2-methyl-1,3-oxathiolan-5-yl)pyrrolidine and of Their Iodomethylates 168
1,4-Diazabicyclo[4.3.0]nonan-9-ones as a new class of highly potent nootropic drugs 168
SAR STUDIES ON THE POTENT AND SELECTIVE MUSCARINIC ANTAGONIST 2-ETHYLTHIO-2,2-DIPHENYLACETIC ACID N,N-DIETHYLAMINOETHYL ESTER 166
SYNTHESIS, CHARACTERIZATION AND PHARMACOLOGICAL PROFILE OF TROPICAMIDE ENANTIOMERS 166
Design of novel nicotinic ligands through 3D database searching 166
SYNTHESIS AND BIOLOGICAL ACTIVITY OF A SERIES OF ARYL TROPANYL ESTERS AND AMIDES CHEMICALLY RELATED TO 1H-INDOLE-3-CARBOXYLIC ACID ENDO 8-METHYL-8-AZABICYCLO[3.2.1]OCT-3-YL ESTER 165
PRESYNAPTIC AUTO- AND HETERO-RECEPTORS IN THE CHOLINERGIC REGULATION OF PAIN 164
Structure-affinity relationships of a unique nicotinic ligand: N1-dimethyl-N4-phenylpiperazinium iodide (DMPP) 164
Aminoarylesters as multidrug resistance (MDR) reverting agents endowed with high potency and efficacy 164
Design, synthesis and preliminary pharmacological evaluation of new piperidine and piperazine derivatives as cognition-enhancers 162
Design, synthesis and pharmacological evaluation of some frozen-analogues of DMPP 162
EC18 as a Tool To Understand the Role of HCN4 Channels in Mediating Hyperpolarization-Activated Current in Tissues 162
DIFFERENTIAL ANALGESIC ACTIVITY OF THE ENANTIOMERS OF ATROPINE DERIVATIVES DOES NOT CORRELATE WITH THEIR MUSCARINIC SUBTYPE SELECTIVITY 161
Designing selective modulators for the nicotinic receptor subtypes: challenges and opportunities 161
N-alkanol-N-cyclohexanol amine aryl esters: Multidrug resistance (MDR) reversing agents with high potency and efficacy 160
Piperazines as nootropic agents: New derivatives of the potent cognition-enhancer DM235 carrying hydrophilic substituents 160
P-glycoprotein and carbonic anhydrases hybrid inhibitors: a new strategy to reverse multidrug resistance (MDR) in cancer cells 160
Carbonic Anhydrase IV Selective Inhibitors Counteract the Development of Colitis-Associated Visceral Pain in Rats 160
"Synthesis and binding properties of photoactivable Biotin-conjugated verapamil derivatives for the study of P-170 glycoprotein" 159
Recent advances in the discovery of Nicotinic acetylcholine receptor allosteric modulators 158
Inhibition of P-glycoprotein-mediated Multidrug Resistance (MDR) by N,N-bis(cyclohexanol)amine aryl esters: further restriction of molecular flexibility maintains high potency and efficacy 158
(E)-3-Furan-2-yl- N- p-tolyl-acrylamide and its Derivative DM489 Decrease Neuropathic Pain in Mice Predominantly by α7 Nicotinic Acetylcholine Receptor Potentiation 158
VERAPAMIL ANALOGUES WITH RESTRICTED MOLECULAR FLEXIBILITY: SYNTHESIS AND PHARMACOLOGICAL EVALUATION OF THE FOUR ISOMERS OF ALPHA-[1-[3-[N-[1-[2-(3,4-DIMETHOXYPHENYL)ETHYL]]-N-METHYLAMINO]CYCLOHEXYL]]-ALPHA-ISOPROPYL-3,4-DIMETHOXYBENZENEACETONITRILE 157
Design, synthesis and preliminary pharmacological evaluation of new analogues of DM232 (unifiram) and DM235 (sunifiram) as cognition modulators. 156
UNEXPECTED REACTIONS OF 2-NITRO-FLUORENE-9-CARBOXYLIC ACID 155
A SEARCH FOR CALCIUM CHANNELS ACTIVATORS IN THE VERAPAMIL SERIES 155
New phenylalkylamines as isoform selective HCN-Channels blockers 155
STRUCTURAL DEPENDENCE OF THE ALLOSTERIC INTERACTION OF SEMI-RIGID VERAPAMIL ANALOGUES WITH DIHYDROPYRIDINE-BINDING IN KITTEN HEART 154
THE FIRST SILICON THIOCYANATE 153
MOLECULAR MODULATION OF MUSCARINIC ANTAGONISTS. SYNTHESIS AND PHARMACOLOGICAL PROFILE OF 2,2-DIPHENYL-2-ETHYLTHIOACETIC AND 3,3-DIPHENYL-3-ETHYLTHIOPROPIONIC ACID DERIVATIVES CHARACTERIZED BY A DIPEPTIDE SPACER 153
REDUCED FLEXIBILITY ANALOGS OF ANALGESIC AND COGNITION-ENHANCING A-TROPANYL ESTERS 150
Design, synthesis and preliminary pharmacological evaluation of new analogues of DM232 (unifiram) and DM235 (sunifiram) as cognition modulators 150
Carbachol dimers with primary carbamate groups as homobivalent modulators of muscarinic receptors 150
Muscarinic antagonists with multiple stereocenters: synthesis, affinity profile and functional activity of isomeric 1-methyl-2-(2,2-alkylaryl-1,3-oxathiolan-5-yl)pyrrolidine sulfoxide derivatives 149
Novel blockers of hyperpolarization-activated current with isoform selectivity in recombinant cells and native tissue. 148
Sulfonamides incorporating piperazine bioisosteres as potent human carbonic anhydrase I, II, IV and IX inhibitors 147
Totale 20.209
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Categoria #
all - tutte 102.583
article - articoli 0
book - libri 0
conference - conferenze 0
curatela - curatele 0
other - altro 0
patent - brevetti 0
selected - selezionate 0
volume - volumi 0
Totale 102.583
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Totale Lug Ago Sett Ott Nov Dic Gen Feb Mar Apr Mag Giu
2020/20211.531 0 0 0 0 0 0 126 278 211 432 137 347
2021/20221.724 53 217 106 69 52 66 89 116 57 61 360 478
2022/20234.462 396 757 196 343 340 847 573 269 469 28 143 101
2023/20241.862 68 197 285 88 137 306 74 410 40 87 90 80
2024/202511.370 428 1.168 738 1.538 3.147 1.674 260 732 532 274 444 435
2025/20267.904 1.399 1.790 1.287 878 1.449 586 515 0 0 0 0 0
Totale 37.804