SCAPECCHI, SERENA
 Distribuzione geografica
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Continente #
NA - Nord America 11.132
EU - Europa 7.474
AS - Asia 4.582
SA - Sud America 494
AF - Africa 147
Continente sconosciuto - Info sul continente non disponibili 146
OC - Oceania 96
Totale 24.071
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Nazione #
US - Stati Uniti d'America 10.940
RU - Federazione Russa 2.266
IT - Italia 1.377
SG - Singapore 1.225
PL - Polonia 1.077
CN - Cina 1.056
HK - Hong Kong 767
SE - Svezia 684
IE - Irlanda 634
VN - Vietnam 590
BR - Brasile 406
KR - Corea 392
UA - Ucraina 313
DE - Germania 305
FI - Finlandia 276
FR - Francia 213
GB - Regno Unito 189
IN - India 160
CA - Canada 118
JP - Giappone 108
AU - Australia 95
TR - Turchia 52
JO - Giordania 44
CI - Costa d'Avorio 39
BD - Bangladesh 38
MX - Messico 35
BE - Belgio 30
IQ - Iraq 28
AR - Argentina 27
NL - Olanda 25
SC - Seychelles 23
NG - Nigeria 21
PK - Pakistan 20
ZA - Sudafrica 20
ID - Indonesia 18
CO - Colombia 16
ES - Italia 14
EC - Ecuador 12
RO - Romania 12
CH - Svizzera 10
SA - Arabia Saudita 10
CL - Cile 9
MA - Marocco 9
UZ - Uzbekistan 9
HU - Ungheria 8
PH - Filippine 8
VE - Venezuela 8
AT - Austria 7
AZ - Azerbaigian 7
EG - Egitto 7
LT - Lituania 7
PY - Paraguay 7
JM - Giamaica 6
NP - Nepal 6
TH - Thailandia 6
CZ - Repubblica Ceca 5
DZ - Algeria 5
MY - Malesia 5
TN - Tunisia 5
AM - Armenia 4
BJ - Benin 4
CR - Costa Rica 4
GT - Guatemala 4
HR - Croazia 4
IL - Israele 4
KZ - Kazakistan 4
LB - Libano 4
PE - Perù 4
TT - Trinidad e Tobago 4
AL - Albania 3
BB - Barbados 3
BG - Bulgaria 3
KE - Kenya 3
NI - Nicaragua 3
PT - Portogallo 3
SK - Slovacchia (Repubblica Slovacca) 3
SN - Senegal 3
UY - Uruguay 3
AE - Emirati Arabi Uniti 2
AO - Angola 2
BS - Bahamas 2
ET - Etiopia 2
EU - Europa 2
GR - Grecia 2
HN - Honduras 2
KG - Kirghizistan 2
LK - Sri Lanka 2
MU - Mauritius 2
OM - Oman 2
PR - Porto Rico 2
PS - Palestinian Territory 2
SV - El Salvador 2
AF - Afghanistan, Repubblica islamica di 1
AG - Antigua e Barbuda 1
BH - Bahrain 1
BO - Bolivia 1
CY - Cipro 1
DK - Danimarca 1
EE - Estonia 1
GA - Gabon 1
Totale 23.912
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Città #
Santa Clara 2.310
Ashburn 1.083
Warsaw 1.070
Singapore 862
Chandler 783
Fairfield 708
Hong Kong 635
Dublin 633
Jacksonville 475
Seoul 388
Woodbridge 342
Cambridge 332
Milan 305
Seattle 305
Houston 264
San Jose 263
Wilmington 259
Beijing 253
Council Bluffs 220
Buffalo 217
Ann Arbor 209
Los Angeles 203
The Dalles 185
Hefei 183
Dong Ket 162
Princeton 155
Boston 136
Ho Chi Minh City 136
Rome 130
Lauterbourg 125
Altamura 107
Mumbai 106
Tokyo 106
Hanoi 103
Boardman 98
Dallas 93
Melbourne 91
Lawrence 80
Florence 78
Munich 77
New York 69
Helsinki 67
Moscow 61
Medford 58
Phoenix 51
Kent 47
Paris 44
San Diego 42
Shanghai 41
Abidjan 39
Turku 37
São Paulo 36
Bologna 32
Falls Church 32
Turin 32
Izmir 31
Philadelphia 31
Brussels 30
Naples 30
Washington 28
Chicago 27
Verona 27
Haiphong 26
London 26
Orem 26
Columbus 25
Toronto 25
Norwalk 24
Abuja 21
Hillsboro 21
Montreal 21
West Jordan 20
Da Nang 19
Figino 19
Guangzhou 19
Frankfurt am Main 18
Genoa 18
Redondo Beach 18
Andover 16
Brooklyn 16
Dearborn 16
Lappeenranta 15
San Francisco 15
Bari 14
Frankfurt Am Main 14
Venice 14
Baghdad 13
Stockholm 13
Tianjin 13
Chennai 12
Johannesburg 12
Palermo 12
Brescia 11
Yubileyny 11
Denver 10
Amman 9
Bengaluru 9
Charlotte 9
Mexico City 9
Miano 9
Totale 15.780
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Nome #
4-Aminopiperidine derivatives as a new class of potent cognition enhancing drugs 416
3-ALFA-TROPANYL 2-(4-Cl-PHENOXY)BUTIRATE (SM21): A REVIEW OF THE PHARMACOLOGICAL PROFILE OF A NOVEL ENHANCER OF CHOLINERGIC TRANSMISSION. 379
The functions and structure of ABC transporters: implications for the design of new inhibitors of Pgp and MRP1 to control multidrug resistance (MDR) 330
Central muscarinic antinociception induced by ET-142 and SS-20 in rodents 317
IMPROVEMENT OF COGNITIVE FUNCTIONS BY THE ACETYLCHOLINE RELEASER SM21 316
Design, synthesis and preliminary pharmacological evaluation of 1,4-diazabicyclo[4.3.0]nonan-9-ones as a new class of highly potent nootropic drugs. 312
Presynaptic Cholinergic Modulators as Potent Cognition Enhancers and Analgesic Drugs. 2. 2-Phenoxy-, 2-(phenylthio)- and 2-(phenylamino)alkanoic Acid Esters 303
ANTINOCICEPTIVE EFFECT OF R-(+)-HYOSCYAMMINE ON THE CONJUNCTIVAL REFLEX TEST IN RABBITS 294
N,N-bis(cyclohexanol)amine aryl esters: the discovery of a new class of highly potent inhibitors of transporter-dependent multidrug resistance (MDR) 283
MOLECULAR MODULATION OF MUSCARINIC ANTAGONISTS. SYNTHESIS AND AFFINITY PROFILE OF 2,2-DIPHENYL-2-ETHYLTHIO-ACETIC ACID ESTERS DESIGNED TO PROBE THE BINDING SITE CAVITY 267
1,3-oxathiolane muscarinic ligands modified at the cationic head. 260
Design, synthesis and preliminary biological evaluation of new isoform-selective f-current blockers. 246
(1,3-Dioxolane)- and (1,3-oxathiolane)-2-pyrrolidines: molecular hybrids with potential anti-Alzheimer activity 232
N,N-bis(cyclohexanol)amine aryl esters: a new class of highly potent Pgp-dependent multidrug resistance (MDR) inhibitors 224
Design, synthesis and preliminary biological evaluation of zatebradine analogues as potential blockers of the hyperpolarization-activated current 218
Design, synthesis and preliminary biological evaluation of new hydroxamate histone deacetylase inhibitors as potential antileukemic agents 218
2-PYRROLIDINONE MOIETY IS NOT CRITICAL FOR THE COGNITION ENHANCING ACTIVITY OF PIRACETAM-LIKE DRUGS 215
1,4-Diazabicyclo[4.3.0]nonan-9-ones and 1,4-diamidopiperazines as new classes of highly potent nootropic drugs 215
Design, Synthesis, and Preliminary Pharmacological Evaluation of New Quinoline Derivatives as Nicotinic Ligands 214
FURTHER STRUCTURE-ACTIVITY RELATIONSHIPS IN THE SERIES OF TROPANYL ESTERS ENDOWED WITH POTENT ANTINOCICEPTIVE ACTIVITY 212
New structure–activity relationship studies in a series of N,N-bis(cyclohexanol)amine aryl esters as potent reversers of P-glycoprotein-mediated multidrug resistance (MDR) 209
SYNTHESIS, AFFINITY PROFILE AND FUNCTIONAL ACTIVITY OF MUSCARINIC ANTAGONISTS WITH A 1-METHYL-2-(2,2-ALKYLARYL-1,3-OXATHIOLAN-5-YL)PYRROLIDINE STRUCTURE 209
ISOMERIC N,N-BIS(CYCLOHEXANOL)AMINE ARYL ESTERS: THE DISCOVERY OF A NEW CLASS OF HIGHLY POTENT P-GLYCOPROTEIN (PGP)-DEPENDENT MULTIDRUG RESISTANCE (MDR) INHIBITORS 208
Highly chiral muscarinic ligands: the discovery of (2S,2'R,3'S,5'R)-1-methyl-2-(2-methyl-1,3-oxathiolan-5-yl)pyrrolidine 3-sulfoxide methyl iodide, a potent, functionally selective, M2 partial agonist. 208
SEMI-RIGID ANALOGUES OF THE CALCIUM ANTAGONIST VERAPAMIL: A MOLECULAR MODELLING STUDY 207
Design, synthesis and nootropic activity of new analogues of sunifiram and sapunifiram, two potent cognition-enhancers. 206
Antagonisti muscarinici a struttura 1,3-ossatiolano-2-pirrolidinica 205
ANALGESIC, ANTIMUSCARINIC ACTIVITY AND ENANTIOSELECTIVITY OF THE FOUR ISOMERS OF 3-QUINUCLIDINYL TROPATE AS COMPARED WITH THE ENANTIOMERS OF HYOSCYAMINE 199
Design, synthesis and preliminary evaluation of a series of histone deacetylase inhibitors carrying a benzodiazepine ring 195
A short synthesis of rigid 2-alkylthio-2,2-diaryl substituted acetic acids 193
Synthesis and Enantioselectivity of the Enantiomers of PG9 and SM21, New Potent Analgesic and Cognition-Enhancing Drugs 192
Synthesis and Cholinergic Affinity of Diastereomeric and Enantiomeric Isomers of 1-Methyl-2-(2-methyl-1,3-dioxolan-4-yl)-pyrrolidine, 1-Methyl-2-(2-methyl-1,3-oxathiolan-5-yl)pyrrolidine and of Their Iodomethylates 192
New phenylalkylamines as isoform selective HCN-Channels blockers 190
R-(+)-HYOSCYAMINE: A PERIPHERAL CHOLINERGIC AMPLIFER 190
1,4-Diazabicyclo[4.3.0]nonan-9-ones as a new class of highly potent nootropic drugs 189
Design, synthesis and pharmacological evaluation of some frozen-analogues of DMPP 187
Design, synthesis and preliminary pharmacological evaluation of new piperidine and piperazine derivatives as cognition-enhancers 185
The medicinal chemistry of multidrug resistance (MDR) reversing drugs 184
SYNTHESIS AND BIOLOGICAL ACTIVITY OF A SERIES OF ARYL TROPANYL ESTERS AND AMIDES CHEMICALLY RELATED TO 1H-INDOLE-3-CARBOXYLIC ACID ENDO 8-METHYL-8-AZABICYCLO[3.2.1]OCT-3-YL ESTER 183
Structure-affinity relationships of a unique nicotinic ligand: N1-dimethyl-N4-phenylpiperazinium iodide (DMPP) 183
Diphenylcyclohexylamine derivatives as new potent multidrug resistance (MDR) modulators 183
Design of novel nicotinic ligands through 3D database searching 181
Chiral synthesis and pharmacological evaluation of the enantiomers of SM32, a new analgesic and cognition-enhancing agent. 181
"Synthesis and binding properties of photoactivable Biotin-conjugated verapamil derivatives for the study of P-170 glycoprotein" 181
Muscarinic antagonists with multiple stereocenters: synthesis, affinity profile and functional activity of isomeric 1-methyl-2-(2,2-alkylaryl-1,3-oxathiolan-5-yl)pyrrolidine sulfoxide derivatives 178
DIFFERENTIAL ANALGESIC ACTIVITY OF THE ENANTIOMERS OF ATROPINE DERIVATIVES DOES NOT CORRELATE WITH THEIR MUSCARINIC SUBTYPE SELECTIVITY 177
Attività analgesica e antimuscarinica ed enantioselettività dei quattro isomeri del tropato del 3-chinuclidinolo messe a confronto con gli enantiomeri della iosciamina 176
PRESYNAPTIC AUTO- AND HETERO-RECEPTORS IN THE CHOLINERGIC REGULATION OF PAIN 175
SAR STUDIES ON THE POTENT AND SELECTIVE MUSCARINIC ANTAGONIST 2-ETHYLTHIO-2,2-DIPHENYLACETIC ACID N,N-DIETHYLAMINOETHYL ESTER 175
MOLECULAR MODULATION OF MUSCARINIC ANTAGONISTS. SYNTHESIS AND PHARMACOLOGICAL PROFILE OF 2,2-DIPHENYL-2-ETHYLTHIOACETIC AND 3,3-DIPHENYL-3-ETHYLTHIOPROPIONIC ACID DERIVATIVES CHARACTERIZED BY A DIPEPTIDE SPACER 175
Design, synthesis and preliminary pharmacological evaluation of new analogues of DM232 (unifiram) and DM235 (sunifiram) as cognition modulators. 175
Inhibition of P-glycoprotein-mediated Multidrug Resistance (MDR) by N,N-bis(cyclohexanol)amine aryl esters: further restriction of molecular flexibility maintains high potency and efficacy 174
Design, synthesis and preliminary pharmacological evaluation of new analogues of DM232 (unifiram) and DM235 (sunifiram) as cognition modulators 174
VERAPAMIL ANALOGUES WITH RESTRICTED MOLECULAR FLEXIBILITY: SYNTHESIS AND PHARMACOLOGICAL EVALUATION OF THE FOUR ISOMERS OF ALPHA-[1-[3-[N-[1-[2-(3,4-DIMETHOXYPHENYL)ETHYL]]-N-METHYLAMINO]CYCLOHEXYL]]-ALPHA-ISOPROPYL-3,4-DIMETHOXYBENZENEACETONITRILE 169
SYNTHESIS AND PHARMACOLOGICAL EVALUATION OF VERAPAMIL ANALOGS WITH RESTRICTED MOLECULAR FLEXIBILITY 166
Presynaptic Cholinergic Modulators as Potent Cognition Enhancers and Analgesic Drugs. 1. Tropic and 2-Phenylpropionic Acid Esters 165
Enantioselective synthesis and preliminary pharmacological evaluation of the enantiomers of unifiram (DM232), a potent cognition-enhancing agent 165
Exploratory chemistry toward the identification of a new class of MDR reverters inspired by pervilleine and verapamil models 165
Muscarinic subtype affinity and functional activity profile of 1-methyl-2-(2-methyl-1,3-dioxolan-4-yl)pyrrolidine and 1-methyl-2-(2-methyl-1,3-oxathiolan-5-yl)pyrrolidine derivatives. 164
Synthesis of Hexahydro-[2]pyrindine(=Hexahydrocyclopenta[c]pyridine) Derivatives as Conformationally Restricted Analogs of the Nicotinic Ligands Arecolone and Isoarecolone 162
REDUCED FLEXIBILITY ANALOGS OF ANALGESIC AND COGNITION-ENHANCING A-TROPANYL ESTERS 161
Analoghi a ridotta flessibilità molecolare di nuovi farmaci ad azione nootropa ed analgesica 161
UNEXPECTED REACTIONS OF 2-NITRO-FLUORENE-9-CARBOXYLIC ACID 160
Alpha-tropanyl esters that increase central ACh release: enantioselectivity studies support a double mechanism of action. 159
A DIRECT METALLATION APPROACH TO 2-ALKYLTHIO-2,2-DIARYL SUBSTITUTED ACETIC ACIDS 157
Synthesis and pharmacological characterization of chiral pyrrolidinylfuran derivatives: the discovery of new functionally selective muscarinic agonists 157
Design, synthesis and preliminary pharmacological evaluation of 4-aminopiperidine derivatives as N-type calcium channel blockers active on pain and neuropathic pain 157
Design, synthesis and preliminary pharmacological evaluation of a set of small molecules that directly activate Gi proteins. 156
3D-QSAR, GRID DESCRIPTORS AND CHEMOMETRIC TOOLS IN THE DEVELOPMENT OF SELECTIVE ANTAGONIST OF MUSCARINIC RECEPTOR. 156
Influence of ring size on the cognition-enhancing activity of DM235 and MN19, two potent nootropic drugs 155
Modulazione molecolare di antagonisti muscarinici. Sintesi e valutazione farmacologica preliminare di esteri amminoalchil piperazinici e piperidinici dell'acido 2,2-difenil-2-etiltioacetico 155
Differential analgesic activity of the enantiomers of atropine derivatives does not correlate with their muscarinic subtype selectivity 154
"Study of the P-glycoprotein functionality after its photolabelling with verapamil analogue in living resistant K562 cells" 154
Structure-activity relationships in 2,2-diphenyl-2-ethylthioacetic acid esters: unexpected agonistic activity in a series of muscarinic antagonists. 153
Design, synthesis and electrophysiological studies of new blockers of HCN channels 153
Inhibition of P-glycoprotein-mediated multidrug resistance (MDR) by N,N-bis(cyclohexanol)amine aryl esters: structure-activity relationships 151
Structure-activity relationship studies on unifiram (DM232) and sunifiram (DM235), two novel and potent cognition enhancing drugs 150
Synthesis, Affinity Profile and Functional Activity of Potent Chiral Muscarinic Antagonists with a Pyrrolidinylfuran Structure 150
Synthesis and pharmacological evaluation of some (pyridyl)cyclopropylmethyl amines and their methiodides as nicotinic receptor ligands. 150
Synthesis and Biological Evaluation of 3,7-Diazabicyclo[4.3.0]2 nonan-8-ones as Potential Nootropic and Analgesic Drugs 149
Design, synthesis and preliminary pharmacological evaluation of 1,4-diaminobenzenes and 1,4-diaminocyclohexanes as cognition modulators 147
DIALKYLAMINOALKYL ESTERS OF 2,2-DIPHENYL-2-ALKYLTIOACETIC ACIDS: A NEW CLASS OF POTENT AND FUNCTIONALLY SELECTIVE MUSCARINIC ANTAGONISTS 147
Design, synthesis and preliminary biological evaluation of new hydroxamate histone deacetylase inhibitors as potential antileukemic agents. 146
AFFINITY PROFILES AT FIVE CLONED HUMAN MUSCARINIC RECEPTORS (M1-M5) OF A NEW SERIES OF ANTIMUSCARINIC DRUGS 144
Design, synthesis and preliminary biological evaluation of new 1,4-benzodiazepine-based compounds as histone deacetylase inhibitors and antileukemic agents 142
New multidrug resistance (MDR) agents endowed with good potency and efficacy 142
New N-alkanol-N-cyclohexanolamine aryl ester derivatives as reverting agents of Multidrug Resistance (MDR) 140
MUSCARINIC PRESYNAPTIC AUTORECEPTORS AND MUSCARINIC POSTSYNAPTIC RECEPTORS HAVE OPPOSITE STEREOCHEMICAL REQUIREMENTS 138
Highly chiral muscarinic ligands: synthesis and affinity of diastereomeric and enantiomeric isomers of 1-methyl-2-(2-methyl-1,3-oxathiolane-5-yl)pyrrolidine 3-sulfoxides and their methyl iodides 137
VERAPAMIL ANALOGUES WITH RESTRICTED MOLECULAR FLEXIBILITY 135
SAR studies in a series of N,N-bis(arylaLKANOL)AMINE ARYL ESTERS AS p-GLYCOPROTEIN (Pgp) dependent multidrug resistance (MDR) inhibitors 135
4-(2-Pyrrolidinyl)-1,3-dioxolane derivatives as ligands for muscarinic and nicotinic receptors 135
NEGATIVE INOTROPIC AND CALCIUM ANTAGONISTIC ACTIVITY OF ALKYL AND ARYLALKYL PHOSPHONATES 134
Structure-activity relationships studies in a series of N,N-bis(alkanol)amine aryl esters as P-glycoprotein (Pgp) dependent multidrug resistance (MDR) inhibitors 133
Design, synthesis and pharmacological evaluation of novel analogues of the two nootropics unifiram (DM232) and sunifiram (DM235) 132
SYNTHESIS AND CARDIOVASCULAR PROPERTIES OF FLUORENYL DERIVATIVES RELATED TO VERAPAMIL 131
N,N-DIETHYLAMINOETHANOL AND N-METHYL-4-PIPERIDINOL ESTERS OF 2,2-DIPHENYL-2-ETHYLTHIOACETIC ACID AS POTENT AND SELECTIVE MUSCARINIC ANTAGONISTS 130
Sintesi e valutazione farmacologica di derivati furanici e tetraidrofuranici a potenziale azione muscarinica 130
synthesis, chiral HPLC separation and pharmacological characterization of muscarinic furan derivatives 130
Design, Synthesis and binding affinity of carbachol dimers as bitopic ligands 129
Totale 18.681
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Categoria #
all - tutte 64.319
article - articoli 0
book - libri 0
conference - conferenze 0
curatela - curatele 0
other - altro 0
patent - brevetti 0
selected - selezionate 0
volume - volumi 0
Totale 64.319
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Totale Lug Ago Sett Ott Nov Dic Gen Feb Mar Apr Mag Giu
2021/2022788 0 0 61 32 32 23 43 51 20 22 229 275
2022/20232.707 250 384 112 262 231 535 353 177 267 14 94 28
2023/20241.095 37 117 182 62 65 228 25 260 9 31 38 41
2024/20256.302 234 674 422 898 1.862 927 53 408 248 156 208 212
2025/20266.730 821 994 646 349 692 304 734 268 429 385 135 973
2026/2027495 221 239 35 0 0 0 0 0 0 0 0 0
Totale 24.071