SCAPECCHI, SERENA
 Distribuzione geografica
Salva come PNG Salva come JPEG
Continente #
NA - Nord America 10.702
EU - Europa 7.429
AS - Asia 4.568
SA - Sud America 483
AF - Africa 147
OC - Oceania 96
Continente sconosciuto - Info sul continente non disponibili 2
Totale 23.427
Salva come PNG Salva come JPEG
Nazione #
US - Stati Uniti d'America 10.601
RU - Federazione Russa 2.266
IT - Italia 1.340
SG - Singapore 1.222
PL - Polonia 1.077
CN - Cina 1.053
HK - Hong Kong 766
SE - Svezia 683
IE - Irlanda 633
VN - Vietnam 589
BR - Brasile 402
KR - Corea 392
UA - Ucraina 313
DE - Germania 304
FI - Finlandia 276
FR - Francia 212
GB - Regno Unito 189
IN - India 160
JP - Giappone 108
AU - Australia 95
TR - Turchia 52
CA - Canada 50
JO - Giordania 44
CI - Costa d'Avorio 39
BD - Bangladesh 38
MX - Messico 34
BE - Belgio 29
IQ - Iraq 28
AR - Argentina 25
NL - Olanda 25
SC - Seychelles 23
NG - Nigeria 21
ZA - Sudafrica 20
PK - Pakistan 19
ID - Indonesia 16
CO - Colombia 13
ES - Italia 12
RO - Romania 12
EC - Ecuador 11
CH - Svizzera 10
SA - Arabia Saudita 10
CL - Cile 9
MA - Marocco 9
UZ - Uzbekistan 9
PH - Filippine 8
VE - Venezuela 8
AT - Austria 7
AZ - Azerbaigian 7
EG - Egitto 7
HU - Ungheria 7
LT - Lituania 7
PY - Paraguay 7
CZ - Repubblica Ceca 5
DZ - Algeria 5
JM - Giamaica 5
NP - Nepal 5
TH - Thailandia 5
TN - Tunisia 5
AM - Armenia 4
BJ - Benin 4
HR - Croazia 4
IL - Israele 4
KZ - Kazakistan 4
LB - Libano 4
MY - Malesia 4
AL - Albania 3
BG - Bulgaria 3
KE - Kenya 3
NI - Nicaragua 3
PE - Perù 3
PT - Portogallo 3
SK - Slovacchia (Repubblica Slovacca) 3
SN - Senegal 3
UY - Uruguay 3
AE - Emirati Arabi Uniti 2
AO - Angola 2
CR - Costa Rica 2
ET - Etiopia 2
EU - Europa 2
GR - Grecia 2
KG - Kirghizistan 2
LK - Sri Lanka 2
MU - Mauritius 2
OM - Oman 2
PS - Palestinian Territory 2
AF - Afghanistan, Repubblica islamica di 1
BB - Barbados 1
BH - Bahrain 1
BO - Bolivia 1
BS - Bahamas 1
CY - Cipro 1
DK - Danimarca 1
EE - Estonia 1
GA - Gabon 1
GY - Guiana 1
HN - Honduras 1
IR - Iran 1
KH - Cambogia 1
KW - Kuwait 1
LA - Repubblica Popolare Democratica del Laos 1
Totale 23.419
Salva come PNG Salva come JPEG
Città #
Santa Clara 2.306
Ashburn 1.071
Warsaw 1.070
Singapore 859
Chandler 783
Fairfield 708
Hong Kong 634
Dublin 632
Jacksonville 474
Seoul 388
Woodbridge 342
Cambridge 331
Milan 303
Seattle 303
Houston 264
Wilmington 259
San Jose 255
Beijing 252
Buffalo 216
Ann Arbor 208
Los Angeles 202
The Dalles 185
Hefei 183
Dong Ket 162
Princeton 155
Boston 136
Ho Chi Minh City 136
Lauterbourg 125
Rome 121
Altamura 107
Mumbai 106
Tokyo 106
Hanoi 103
Boardman 98
Dallas 93
Melbourne 91
Lawrence 80
Florence 77
Munich 76
Council Bluffs 71
Helsinki 67
New York 67
Moscow 61
Medford 58
Kent 47
Paris 44
San Diego 41
Shanghai 41
Abidjan 39
Turku 37
São Paulo 36
Phoenix 33
Bologna 32
Falls Church 32
Izmir 31
Turin 31
Brussels 29
Philadelphia 29
Washington 28
Naples 27
Verona 27
Haiphong 26
Orem 26
Norwalk 24
London 23
Abuja 21
Hillsboro 20
West Jordan 20
Da Nang 19
Figino 19
Guangzhou 19
Toronto 19
Frankfurt am Main 18
Redondo Beach 18
Genoa 17
Andover 16
Dearborn 16
Brooklyn 15
Lappeenranta 15
San Francisco 15
Bari 14
Chicago 14
Frankfurt Am Main 14
Baghdad 13
Montreal 13
Stockholm 13
Tianjin 13
Venice 13
Chennai 12
Johannesburg 12
Palermo 12
Yubileyny 11
Brescia 10
Denver 10
Amman 9
Bengaluru 9
Mexico City 9
Miano 9
Rio de Janeiro 9
Auburn Hills 8
Totale 15.501
Salva come PNG Salva come JPEG
Nome #
4-Aminopiperidine derivatives as a new class of potent cognition enhancing drugs 408
3-ALFA-TROPANYL 2-(4-Cl-PHENOXY)BUTIRATE (SM21): A REVIEW OF THE PHARMACOLOGICAL PROFILE OF A NOVEL ENHANCER OF CHOLINERGIC TRANSMISSION. 375
The functions and structure of ABC transporters: implications for the design of new inhibitors of Pgp and MRP1 to control multidrug resistance (MDR) 324
Central muscarinic antinociception induced by ET-142 and SS-20 in rodents 312
IMPROVEMENT OF COGNITIVE FUNCTIONS BY THE ACETYLCHOLINE RELEASER SM21 308
Design, synthesis and preliminary pharmacological evaluation of 1,4-diazabicyclo[4.3.0]nonan-9-ones as a new class of highly potent nootropic drugs. 306
Presynaptic Cholinergic Modulators as Potent Cognition Enhancers and Analgesic Drugs. 2. 2-Phenoxy-, 2-(phenylthio)- and 2-(phenylamino)alkanoic Acid Esters 301
ANTINOCICEPTIVE EFFECT OF R-(+)-HYOSCYAMMINE ON THE CONJUNCTIVAL REFLEX TEST IN RABBITS 289
N,N-bis(cyclohexanol)amine aryl esters: the discovery of a new class of highly potent inhibitors of transporter-dependent multidrug resistance (MDR) 276
MOLECULAR MODULATION OF MUSCARINIC ANTAGONISTS. SYNTHESIS AND AFFINITY PROFILE OF 2,2-DIPHENYL-2-ETHYLTHIO-ACETIC ACID ESTERS DESIGNED TO PROBE THE BINDING SITE CAVITY 260
1,3-oxathiolane muscarinic ligands modified at the cationic head. 255
Design, synthesis and preliminary biological evaluation of new isoform-selective f-current blockers. 245
(1,3-Dioxolane)- and (1,3-oxathiolane)-2-pyrrolidines: molecular hybrids with potential anti-Alzheimer activity 226
N,N-bis(cyclohexanol)amine aryl esters: a new class of highly potent Pgp-dependent multidrug resistance (MDR) inhibitors 220
Design, synthesis and preliminary biological evaluation of new hydroxamate histone deacetylase inhibitors as potential antileukemic agents 215
Design, synthesis and preliminary biological evaluation of zatebradine analogues as potential blockers of the hyperpolarization-activated current 213
Design, Synthesis, and Preliminary Pharmacological Evaluation of New Quinoline Derivatives as Nicotinic Ligands 211
1,4-Diazabicyclo[4.3.0]nonan-9-ones and 1,4-diamidopiperazines as new classes of highly potent nootropic drugs 211
FURTHER STRUCTURE-ACTIVITY RELATIONSHIPS IN THE SERIES OF TROPANYL ESTERS ENDOWED WITH POTENT ANTINOCICEPTIVE ACTIVITY 208
2-PYRROLIDINONE MOIETY IS NOT CRITICAL FOR THE COGNITION ENHANCING ACTIVITY OF PIRACETAM-LIKE DRUGS 207
New structure–activity relationship studies in a series of N,N-bis(cyclohexanol)amine aryl esters as potent reversers of P-glycoprotein-mediated multidrug resistance (MDR) 207
Highly chiral muscarinic ligands: the discovery of (2S,2'R,3'S,5'R)-1-methyl-2-(2-methyl-1,3-oxathiolan-5-yl)pyrrolidine 3-sulfoxide methyl iodide, a potent, functionally selective, M2 partial agonist. 207
SYNTHESIS, AFFINITY PROFILE AND FUNCTIONAL ACTIVITY OF MUSCARINIC ANTAGONISTS WITH A 1-METHYL-2-(2,2-ALKYLARYL-1,3-OXATHIOLAN-5-YL)PYRROLIDINE STRUCTURE 205
SEMI-RIGID ANALOGUES OF THE CALCIUM ANTAGONIST VERAPAMIL: A MOLECULAR MODELLING STUDY 203
Design, synthesis and nootropic activity of new analogues of sunifiram and sapunifiram, two potent cognition-enhancers. 203
ISOMERIC N,N-BIS(CYCLOHEXANOL)AMINE ARYL ESTERS: THE DISCOVERY OF A NEW CLASS OF HIGHLY POTENT P-GLYCOPROTEIN (PGP)-DEPENDENT MULTIDRUG RESISTANCE (MDR) INHIBITORS 202
Antagonisti muscarinici a struttura 1,3-ossatiolano-2-pirrolidinica 202
ANALGESIC, ANTIMUSCARINIC ACTIVITY AND ENANTIOSELECTIVITY OF THE FOUR ISOMERS OF 3-QUINUCLIDINYL TROPATE AS COMPARED WITH THE ENANTIOMERS OF HYOSCYAMINE 196
Design, synthesis and preliminary evaluation of a series of histone deacetylase inhibitors carrying a benzodiazepine ring 193
Synthesis and Enantioselectivity of the Enantiomers of PG9 and SM21, New Potent Analgesic and Cognition-Enhancing Drugs 190
A short synthesis of rigid 2-alkylthio-2,2-diaryl substituted acetic acids 189
Synthesis and Cholinergic Affinity of Diastereomeric and Enantiomeric Isomers of 1-Methyl-2-(2-methyl-1,3-dioxolan-4-yl)-pyrrolidine, 1-Methyl-2-(2-methyl-1,3-oxathiolan-5-yl)pyrrolidine and of Their Iodomethylates 189
New phenylalkylamines as isoform selective HCN-Channels blockers 188
R-(+)-HYOSCYAMINE: A PERIPHERAL CHOLINERGIC AMPLIFER 187
Design, synthesis and pharmacological evaluation of some frozen-analogues of DMPP 185
1,4-Diazabicyclo[4.3.0]nonan-9-ones as a new class of highly potent nootropic drugs 184
Structure-affinity relationships of a unique nicotinic ligand: N1-dimethyl-N4-phenylpiperazinium iodide (DMPP) 181
Design, synthesis and preliminary pharmacological evaluation of new piperidine and piperazine derivatives as cognition-enhancers 181
Diphenylcyclohexylamine derivatives as new potent multidrug resistance (MDR) modulators 181
SYNTHESIS AND BIOLOGICAL ACTIVITY OF A SERIES OF ARYL TROPANYL ESTERS AND AMIDES CHEMICALLY RELATED TO 1H-INDOLE-3-CARBOXYLIC ACID ENDO 8-METHYL-8-AZABICYCLO[3.2.1]OCT-3-YL ESTER 178
Chiral synthesis and pharmacological evaluation of the enantiomers of SM32, a new analgesic and cognition-enhancing agent. 178
Design of novel nicotinic ligands through 3D database searching 177
The medicinal chemistry of multidrug resistance (MDR) reversing drugs 177
DIFFERENTIAL ANALGESIC ACTIVITY OF THE ENANTIOMERS OF ATROPINE DERIVATIVES DOES NOT CORRELATE WITH THEIR MUSCARINIC SUBTYPE SELECTIVITY 176
"Synthesis and binding properties of photoactivable Biotin-conjugated verapamil derivatives for the study of P-170 glycoprotein" 176
Muscarinic antagonists with multiple stereocenters: synthesis, affinity profile and functional activity of isomeric 1-methyl-2-(2,2-alkylaryl-1,3-oxathiolan-5-yl)pyrrolidine sulfoxide derivatives 175
PRESYNAPTIC AUTO- AND HETERO-RECEPTORS IN THE CHOLINERGIC REGULATION OF PAIN 172
Inhibition of P-glycoprotein-mediated Multidrug Resistance (MDR) by N,N-bis(cyclohexanol)amine aryl esters: further restriction of molecular flexibility maintains high potency and efficacy 172
SAR STUDIES ON THE POTENT AND SELECTIVE MUSCARINIC ANTAGONIST 2-ETHYLTHIO-2,2-DIPHENYLACETIC ACID N,N-DIETHYLAMINOETHYL ESTER 171
Attività analgesica e antimuscarinica ed enantioselettività dei quattro isomeri del tropato del 3-chinuclidinolo messe a confronto con gli enantiomeri della iosciamina 171
Design, synthesis and preliminary pharmacological evaluation of new analogues of DM232 (unifiram) and DM235 (sunifiram) as cognition modulators. 171
Design, synthesis and preliminary pharmacological evaluation of new analogues of DM232 (unifiram) and DM235 (sunifiram) as cognition modulators 170
MOLECULAR MODULATION OF MUSCARINIC ANTAGONISTS. SYNTHESIS AND PHARMACOLOGICAL PROFILE OF 2,2-DIPHENYL-2-ETHYLTHIOACETIC AND 3,3-DIPHENYL-3-ETHYLTHIOPROPIONIC ACID DERIVATIVES CHARACTERIZED BY A DIPEPTIDE SPACER 170
VERAPAMIL ANALOGUES WITH RESTRICTED MOLECULAR FLEXIBILITY: SYNTHESIS AND PHARMACOLOGICAL EVALUATION OF THE FOUR ISOMERS OF ALPHA-[1-[3-[N-[1-[2-(3,4-DIMETHOXYPHENYL)ETHYL]]-N-METHYLAMINO]CYCLOHEXYL]]-ALPHA-ISOPROPYL-3,4-DIMETHOXYBENZENEACETONITRILE 165
Presynaptic Cholinergic Modulators as Potent Cognition Enhancers and Analgesic Drugs. 1. Tropic and 2-Phenylpropionic Acid Esters 162
Enantioselective synthesis and preliminary pharmacological evaluation of the enantiomers of unifiram (DM232), a potent cognition-enhancing agent 162
SYNTHESIS AND PHARMACOLOGICAL EVALUATION OF VERAPAMIL ANALOGS WITH RESTRICTED MOLECULAR FLEXIBILITY 161
Exploratory chemistry toward the identification of a new class of MDR reverters inspired by pervilleine and verapamil models 160
Muscarinic subtype affinity and functional activity profile of 1-methyl-2-(2-methyl-1,3-dioxolan-4-yl)pyrrolidine and 1-methyl-2-(2-methyl-1,3-oxathiolan-5-yl)pyrrolidine derivatives. 160
UNEXPECTED REACTIONS OF 2-NITRO-FLUORENE-9-CARBOXYLIC ACID 159
REDUCED FLEXIBILITY ANALOGS OF ANALGESIC AND COGNITION-ENHANCING A-TROPANYL ESTERS 158
Analoghi a ridotta flessibilità molecolare di nuovi farmaci ad azione nootropa ed analgesica 157
Synthesis of Hexahydro-[2]pyrindine(=Hexahydrocyclopenta[c]pyridine) Derivatives as Conformationally Restricted Analogs of the Nicotinic Ligands Arecolone and Isoarecolone 156
Design, synthesis and preliminary pharmacological evaluation of 4-aminopiperidine derivatives as N-type calcium channel blockers active on pain and neuropathic pain 155
A DIRECT METALLATION APPROACH TO 2-ALKYLTHIO-2,2-DIARYL SUBSTITUTED ACETIC ACIDS 154
Synthesis and pharmacological characterization of chiral pyrrolidinylfuran derivatives: the discovery of new functionally selective muscarinic agonists 154
Influence of ring size on the cognition-enhancing activity of DM235 and MN19, two potent nootropic drugs 154
Alpha-tropanyl esters that increase central ACh release: enantioselectivity studies support a double mechanism of action. 154
Design, synthesis and preliminary pharmacological evaluation of a set of small molecules that directly activate Gi proteins. 153
Design, synthesis and electrophysiological studies of new blockers of HCN channels 152
Differential analgesic activity of the enantiomers of atropine derivatives does not correlate with their muscarinic subtype selectivity 152
Modulazione molecolare di antagonisti muscarinici. Sintesi e valutazione farmacologica preliminare di esteri amminoalchil piperazinici e piperidinici dell'acido 2,2-difenil-2-etiltioacetico 152
3D-QSAR, GRID DESCRIPTORS AND CHEMOMETRIC TOOLS IN THE DEVELOPMENT OF SELECTIVE ANTAGONIST OF MUSCARINIC RECEPTOR. 151
"Study of the P-glycoprotein functionality after its photolabelling with verapamil analogue in living resistant K562 cells" 150
Structure-activity relationship studies on unifiram (DM232) and sunifiram (DM235), two novel and potent cognition enhancing drugs 148
Structure-activity relationships in 2,2-diphenyl-2-ethylthioacetic acid esters: unexpected agonistic activity in a series of muscarinic antagonists. 148
Inhibition of P-glycoprotein-mediated multidrug resistance (MDR) by N,N-bis(cyclohexanol)amine aryl esters: structure-activity relationships 148
Synthesis and Biological Evaluation of 3,7-Diazabicyclo[4.3.0]2 nonan-8-ones as Potential Nootropic and Analgesic Drugs 147
Synthesis, Affinity Profile and Functional Activity of Potent Chiral Muscarinic Antagonists with a Pyrrolidinylfuran Structure 147
Synthesis and pharmacological evaluation of some (pyridyl)cyclopropylmethyl amines and their methiodides as nicotinic receptor ligands. 147
Design, synthesis and preliminary pharmacological evaluation of 1,4-diaminobenzenes and 1,4-diaminocyclohexanes as cognition modulators 143
Design, synthesis and preliminary biological evaluation of new hydroxamate histone deacetylase inhibitors as potential antileukemic agents. 143
AFFINITY PROFILES AT FIVE CLONED HUMAN MUSCARINIC RECEPTORS (M1-M5) OF A NEW SERIES OF ANTIMUSCARINIC DRUGS 142
DIALKYLAMINOALKYL ESTERS OF 2,2-DIPHENYL-2-ALKYLTIOACETIC ACIDS: A NEW CLASS OF POTENT AND FUNCTIONALLY SELECTIVE MUSCARINIC ANTAGONISTS 142
New multidrug resistance (MDR) agents endowed with good potency and efficacy 139
New N-alkanol-N-cyclohexanolamine aryl ester derivatives as reverting agents of Multidrug Resistance (MDR) 138
MUSCARINIC PRESYNAPTIC AUTORECEPTORS AND MUSCARINIC POSTSYNAPTIC RECEPTORS HAVE OPPOSITE STEREOCHEMICAL REQUIREMENTS 137
Design, synthesis and preliminary biological evaluation of new 1,4-benzodiazepine-based compounds as histone deacetylase inhibitors and antileukemic agents 137
Highly chiral muscarinic ligands: synthesis and affinity of diastereomeric and enantiomeric isomers of 1-methyl-2-(2-methyl-1,3-oxathiolane-5-yl)pyrrolidine 3-sulfoxides and their methyl iodides 135
Structure-activity relationships studies in a series of N,N-bis(alkanol)amine aryl esters as P-glycoprotein (Pgp) dependent multidrug resistance (MDR) inhibitors 132
SAR studies in a series of N,N-bis(arylaLKANOL)AMINE ARYL ESTERS AS p-GLYCOPROTEIN (Pgp) dependent multidrug resistance (MDR) inhibitors 132
VERAPAMIL ANALOGUES WITH RESTRICTED MOLECULAR FLEXIBILITY 131
4-(2-Pyrrolidinyl)-1,3-dioxolane derivatives as ligands for muscarinic and nicotinic receptors 131
Design, synthesis and pharmacological evaluation of novel analogues of the two nootropics unifiram (DM232) and sunifiram (DM235) 130
NEGATIVE INOTROPIC AND CALCIUM ANTAGONISTIC ACTIVITY OF ALKYL AND ARYLALKYL PHOSPHONATES 129
SYNTHESIS AND CARDIOVASCULAR PROPERTIES OF FLUORENYL DERIVATIVES RELATED TO VERAPAMIL 129
synthesis, chiral HPLC separation and pharmacological characterization of muscarinic furan derivatives 128
Design, Synthesis and binding affinity of carbachol dimers as bitopic ligands 127
Exploratory Chemistry toward the identification of new classes of MDR reverters 127
Influence of ring size on the cognition-enhancing activity of DM235 and MN19, two potent nootropic drugs 127
Totale 18.322
Salva come PNG Salva come JPEG
Categoria #
all - tutte 61.785
article - articoli 0
book - libri 0
conference - conferenze 0
curatela - curatele 0
other - altro 0
patent - brevetti 0
selected - selezionate 0
volume - volumi 0
Totale 61.785
Salva come PNG Salva come JPEG


Totale Lug Ago Sett Ott Nov Dic Gen Feb Mar Apr Mag Giu
2020/2021262 0 0 0 0 0 0 0 0 0 0 0 262
2021/2022988 34 166 61 32 32 23 43 51 20 22 229 275
2022/20232.707 250 384 112 262 231 535 353 177 267 14 94 28
2023/20241.095 37 117 182 62 65 228 25 260 9 31 38 41
2024/20256.302 234 674 422 898 1.862 927 53 408 248 156 208 212
2025/20266.725 821 994 646 349 692 304 734 268 429 385 135 968
Totale 23.571