FRAGAI, MARCO
 Distribuzione geografica
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Continente #
NA - Nord America 13.717
EU - Europa 8.262
AS - Asia 7.234
SA - Sud America 1.042
AF - Africa 172
OC - Oceania 88
Continente sconosciuto - Info sul continente non disponibili 3
Totale 30.518
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Nazione #
US - Stati Uniti d'America 13.526
RU - Federazione Russa 2.959
HK - Hong Kong 1.775
SG - Singapore 1.660
CN - Cina 1.611
IT - Italia 1.266
PL - Polonia 889
BR - Brasile 832
VN - Vietnam 769
SE - Svezia 767
IE - Irlanda 711
KR - Corea 539
DE - Germania 395
FR - Francia 314
FI - Finlandia 289
IN - India 238
GB - Regno Unito 188
BD - Bangladesh 115
CA - Canada 96
UA - Ucraina 94
CH - Svizzera 93
AU - Australia 86
JP - Giappone 86
NL - Olanda 86
ID - Indonesia 83
AR - Argentina 82
JO - Giordania 82
TR - Turchia 71
MX - Messico 59
EC - Ecuador 44
IQ - Iraq 44
ES - Italia 42
ZA - Sudafrica 36
AT - Austria 34
CI - Costa d'Avorio 34
BE - Belgio 33
CO - Colombia 24
PK - Pakistan 18
MA - Marocco 17
NG - Nigeria 17
PY - Paraguay 17
IR - Iran 15
SA - Arabia Saudita 15
GR - Grecia 14
AE - Emirati Arabi Uniti 13
VE - Venezuela 12
AZ - Azerbaigian 11
CL - Cile 11
CZ - Repubblica Ceca 11
PH - Filippine 11
UZ - Uzbekistan 11
BJ - Benin 10
DK - Danimarca 10
EG - Egitto 10
CM - Camerun 9
IL - Israele 9
KE - Kenya 9
TW - Taiwan 9
BG - Bulgaria 8
JM - Giamaica 8
LT - Lituania 8
MY - Malesia 8
PT - Portogallo 8
RO - Romania 8
UY - Uruguay 8
KZ - Kazakistan 7
PE - Perù 7
TN - Tunisia 7
NO - Norvegia 6
DZ - Algeria 5
HU - Ungheria 5
SN - Senegal 5
BO - Bolivia 4
CR - Costa Rica 4
GE - Georgia 4
NP - Nepal 4
PR - Porto Rico 4
SC - Seychelles 4
TH - Thailandia 4
BY - Bielorussia 3
DO - Repubblica Dominicana 3
EE - Estonia 3
GT - Guatemala 3
KG - Kirghizistan 3
LB - Libano 3
ML - Mali 3
OM - Oman 3
PA - Panama 3
RS - Serbia 3
SV - El Salvador 3
TT - Trinidad e Tobago 3
AL - Albania 2
BB - Barbados 2
ET - Etiopia 2
EU - Europa 2
GA - Gabon 2
HR - Croazia 2
KW - Kuwait 2
LI - Liechtenstein 2
MD - Moldavia 2
Totale 30.491
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Città #
Santa Clara 3.263
Hong Kong 1.629
Ashburn 1.511
Singapore 1.229
Fairfield 1.207
Warsaw 879
Dublin 711
Chandler 673
Woodbridge 546
Seattle 532
Seoul 517
Houston 455
Cambridge 440
Wilmington 376
Florence 373
Hefei 362
San Jose 356
Ann Arbor 313
Beijing 308
Ho Chi Minh City 221
Lawrence 220
Altamura 199
Jacksonville 195
The Dalles 173
Hanoi 170
Princeton 167
Lauterbourg 166
Moscow 160
Los Angeles 148
Dallas 146
Buffalo 145
Mumbai 141
Milan 104
Munich 103
Helsinki 100
Medford 96
Boston 94
Council Bluffs 87
New York 87
Melbourne 84
Bern 81
São Paulo 81
Boardman 79
Tokyo 70
Shanghai 66
Turku 65
San Diego 64
Kent 59
Dong Ket 58
Jakarta 56
Clifton 54
Paris 48
Lappeenranta 43
Haiphong 42
Chicago 39
Frankfurt am Main 39
Atlanta 35
Rio de Janeiro 35
Abidjan 34
Redondo Beach 34
Izmir 33
Norwalk 33
Bremen 32
Rome 31
Brussels 30
Toronto 30
Da Nang 29
Orem 29
Falls Church 28
London 28
Vienna 25
Andover 22
Hillsboro 21
Naples 21
Barcelona 20
Belo Horizonte 20
Phoenix 20
Biên Hòa 19
Guangzhou 19
Johannesburg 19
Padova 19
Bengaluru 18
Chennai 18
Montreal 18
Abuja 17
Camden 17
Nuremberg 17
Yubileyny 17
Baghdad 16
Brooklyn 16
Stockholm 16
West Jordan 16
Falkenstein 15
Guayaquil 15
Turin 15
Redmond 14
Redwood City 14
Amsterdam 13
Campinas 13
Philadelphia 13
Totale 20.594
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Nome #
Regulation of HuR structure and function by dihydrotanshinone-I 1.011
1 H-detected solid-state NMR of proteins entrapped in bioinspired silica: A new tool for biomaterials characterization 718
Seed amplification assays for diagnosing synucleinopathies: The issue of influencing factors 617
Persistent contrast enhancement by sterically stabilized paramagnetic liposomes in murine melanoma. 302
High-Resolution Solid-State NMR Characterization of Ligand Binding to a Protein Immobilized in a Silica Matrix 285
Long-range paramagnetic NMR data can provide a closer look on metal coordination in metalloproteins 270
Characterization of the Conjugation Pattern in Large Polysaccharide-Protein Conjugates by NMR Spectroscopy 269
Acido Ialuronico funzionalizzato 264
H-1 NMRD profiles of diamagnetic proteins: a model-free analysis 254
Aggregation kinetics of the Aβ1-40 peptide monitored by NMR 247
Characterization of PEGylated Asparaginase: New Opportunities from NMR Analysis of Large PEGylated Therapeutics 246
Real-Time Insights into Biological Events: In-Cell Processes and Protein-Ligand Interactions 242
G-triplex structure and formation propensity 238
Lipoyl-Homotaurine Derivative (ADM_12) Reverts Oxaliplatin-Induced Neuropathy and Reduces Cancer Cells Malignancy by Inhibiting Carbonic Anhydrase IX (CAIX) 233
Integrative Approaches in Structural Biology: A More Complete Picture from the Combination of Individual Techniques 229
A small heterobifunctional ligand provides stable and water dispersible core-shell CdSe/ZnS quantum dots (QDs) 229
Bilayer Membrane Modulation of Membrane Type 1 Matrix Metalloproteinase (MT1-MMP) Structure and Proteolytic Activity 223
Atomic structural details of a protein grafted onto gold nanoparticles 219
Biomolecular NMR at 1.2 GHz 219
Active-Site Targeting Paramagnetic Probe for Matrix Metalloproteinases 217
The G-Triplex DNA 214
Engineering l-asparaginase for spontaneous formation of calcium phosphate bioinspired microreactors. 213
AZA-Tanshinone derivatives, process for their preparation and their use in therapy 213
A protocol to automatically calculate homo-oligomeric protein structures through the integration of evolutionary constraints and NMR ambiguous contacts 213
NMR study of the secondary structure and biopharmaceutical formulation of an active branched antimicrobial peptide 211
Epitope Mapping and Binding Assessment by Solid-State NMR Provide a Way for the Development of Biologics under the Quality by Design Paradigm 209
Structural characterization of a protein adsorbed on aluminum hydroxide adjuvant in vaccine formulation 209
Insights into telomeric G-quadruplex DNA recognition by HMGB1 protein 204
Atomic-Level Quality Assessment of Enzymes Encapsulated in Bioinspired Silica 203
Solid-State NMR of PEGylated Proteins 202
Dissecting the Interactions between Human Serum Albumin and α-Synuclein: New Insights on the Factors Influencing α-Synuclein Aggregation in Biological Fluids 201
A Divalent PAMAM-Based Matrix Metalloproteinase/Carbonic Anhydrase Inhibitor for the Treatment of Dry Eye Syndrome 200
Simultaneous Targeting of RGD-Integrins and Dual Murine Double Minute Proteins in Glioblastoma Multiforme 199
A Highly Soluble Matrix Metalloproteinase-9 Inhibitor for Potential Treatment of Dry Eye Syndrome 198
Biosilica and bioinspired silica studied by solid-state NMR 198
Interfering with HuR-RNA Interaction: Design, Synthesis and Biological Characterization of Tanshinone Mimics as Novel, Effective HuR Inhibitors 198
Algal autolysate medium to label proteins for NMR in mammalian cells 197
NMR of sedimented, fibrillized, silica-entrapped and microcrystalline (metallo)proteins 195
Exploring the subtleties of drug-receptor interactions: The case of matrix metalloproteinases 195
Functionalized Hyaluronic Acid 194
Theoretical and experimental studies on the interaction of biphenyl ligands with human and murine PD-L1: Up-to-date clues for drug design 192
Combining Solid-State NMR with Structural and Biophysical Techniques to Design Challenging Protein-Drug Conjugates 191
In situ AP/MALDI-MS characterization of anchored matrix metalloproteinases 190
A Structurally Simple Vaccine Candidate Reduces Progression and Dissemination of Triple-Negative Breast Cancer 190
Paramagnetic metal ions in ligand screening: The Co-II matrix metalloproteinase 12 189
Structural basis for matrix metalloproteinase 1-catalyzed collagenolysis 189
Discovery of a New Class of Potent MMP Inhibitors by Structure-Based Optimization of the Arylsulfonamide Scaffold 189
A new methodology for monitoring the activity of cdMMP-12 anchored and freeze-dried on Au(111) 185
A new NT4 peptide-based drug delivery system for cancer treatment 185
Crystal structure of the catalytic domain of human matrix metalloproteinase 10 184
Biosilica-Entrapped Enzymes Studied by Using Dynamic Nuclear-Polarization-Enhanced High-Field NMR Spectroscopy 184
Conformational variability of matrix metalloproteinases: beyond a single 3D structure 182
Biotin-tagged probes for MMP expression and activation: design, synthesis, and binding properties 182
Activity of anchored human matrix metalloproteinase-1 catalytic domain on Au(111) surfaces monitored by ESI-MS 180
1H NMRD dispersions of porous media: a model-free analysis 180
Solid-state NMR of matrix metalloproteinase 12: An approach complementary to solution NMR 180
Metal centers in biomolecular solid-state NMR 178
Substrate specificities of matrix metalloproteinase 1 in PAR-1 exodomain proteolysis 177
"Four-dimensional" protein structures: Examples from metalloproteins 177
Structural basis of serine/threonine phosphatase inhibition by the archetypal small molecules cantharidin and norcantharidin 177
Automated Determination of Nuclear Magnetic Resonance Chemical Shift Perturbations in Ligand Screening Experiments: The PICASSO Web Server 177
Molecular Insights into O-Linked Sialoglycans Recognition by the Siglec-Like SLBR-N (SLBRUB10712) of Streptococcus gordonii 176
Snapshots of the reaction mechanism of matrix metalloproteinases 176
Computer-Aided Identification and Lead Optimization of Dual Murine Double Minute 2 and 4 Binders: Structure-Activity Relationship Studies and Pharmacological Activity 176
Structure-Based Approach to Nanomolar, Water Soluble Matrix Metalloproteinases Inhibitors (MMPIs) 175
Combining in silico tools and NMR data to validate protein-ligand structural models: Application to matrix metalloproteinases 175
Mixing Aβ(1-40) and Aβ(1-42) peptides generates unique amyloid fibrils 174
Large Protein Assemblies for High-Relaxivity Contrast Agents: The Case of Gadolinium-Labeled Asparaginase 173
Synthesis and binding monitoring of a new nanomolar PAMAM-based matrix metalloproteinases inhibitor (MMPIs) 173
A high-affinity carbohydrate-containing inhibitor of matrix metalloproteinases 172
A high-resolution view of the coordination environment in a paramagnetic metalloprotein from its magnetic properties 172
Entropic contribution to the linking coefficient in fragment based drug design: a case study. 172
Identification and Characterization of an RRM-Containing, RNA Binding Protein in Acinetobacter baumannii 171
Unraveling Hidden Regulatory Sites in Structurally Homologous Metalloproteases 170
Functionalized Hyaluronic Acid for “In Situ” Matrix Metalloproteinase Inhibition: A Bioactive Material to Treat the Dry Eye Sydrome 168
Targeting Matrix Metalloproteinases: Design of a Bifunctional Inhibitor for Presentation by Tumour-Associated Galectins 166
1H NMR Relaxometric Study of Chitosan-Based Nanogels Containing Mono- And Bis-Hydrated Gd(III) Chelates: Clues for MRI Probes of Improved Sensitivity 166
Water-based ligand screening for paramagnetic metalloproteins 164
Solution structure and dynamics of human S100A14 164
Differences in Dynamics between Crosslinked and Non-Crosslinked Hyaluronates Measured by using Fast Field-Cycling Relaxometry 163
Cerebrospinal fluid lipoproteins inhibit α-synuclein aggregation by interacting with oligomeric species in seed amplification assays 163
HuR-targeted agents: An insight into medicinal chemistry, biophysical, computational studies and pharmacological effects on cancer models 162
Evidence of reciprocal reorientation of the catalytic and hemopexin-like domains of full-length MMP-12 161
Paramagnetic NMR as a new tool in structural biology 160
Quantum Dot-Based Probes for Labeling and Imaging of Cells that Express Matrix Metalloproteinases 160
NMR quality control of fragment libraries for screening 160
CXCR4 antagonism sensitizes cancer cells to novel indole-based MDM2/4 inhibitors in glioblastoma multiforme 160
Elucidating the concentration-dependent effects of thiocyanate binding to carbonic anhydrase 159
Design in silico, synthesis and binding evaluation of a carbohydrate-based scaffold for structurally novel inhibitors of matrix metalloproteinases 159
Conformational freedom of metalloproteins revealed by paramagnetism-assisted NMR 157
NMR characterization of the C-terminal tail of full-length RAGE in a membrane mimicking environment 157
SSNMR of biosilica-entrapped enzymes permits an easy assessment of preservation of native conformation in atomic detail 157
alpha ',alpha '-dioxothiones, III Regio- and stereoselective ene and tandem "ene-cycloaddition'' reactions of 2,4-dioxopentane-3-thione 156
Sulfonamide-functionalized gadolinium DTPA complexes as possible contrast agents for MRI: A relaxometric investigation 156
Insights into Domain-Domain Motions in Proteins and RNA from Solution NMR 156
Site-Selective Functionalized PD-1 Mutant for a Modular Immunological Activity against Cancer Cells 154
A calix[4]arene Gd-III complex endowed with high stability, relaxivity, and binding affinity to serum albumin 154
Molecular Determinants of a Selective Matrix Metalloprotease-12 Inhibitor: Insights from Crystallography and Thermodynamic Studies 154
Nanoparticles for the multivalent presentation of a TnThr mimetic and as tool for solid state NMR coating investigation 154
Paramagnetic Properties of a Crystalline Iron-Sulfur Protein by Magic-Angle Spinning NMR Spectroscopy 154
Totale 20.855
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Categoria #
all - tutte 83.207
article - articoli 0
book - libri 0
conference - conferenze 0
curatela - curatele 0
other - altro 0
patent - brevetti 0
selected - selezionate 0
volume - volumi 0
Totale 83.207
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Totale Lug Ago Sett Ott Nov Dic Gen Feb Mar Apr Mag Giu
2020/2021142 0 0 0 0 0 0 0 0 0 0 0 142
2021/20221.227 52 79 110 54 61 56 61 103 87 52 201 311
2022/20233.200 293 620 186 270 219 561 420 140 271 36 79 105
2023/20241.286 70 135 174 77 84 198 52 217 26 119 75 59
2024/20259.029 305 834 639 1.337 2.422 1.462 200 625 309 182 346 368
2025/20269.824 900 2.275 967 1.049 1.073 387 1.101 507 610 593 357 5
Totale 30.827