FRAGAI, MARCO
 Distribuzione geografica
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Continente #
NA - Nord America 14.852
EU - Europa 9.453
AS - Asia 7.315
SA - Sud America 1.076
Continente sconosciuto - Info sul continente non disponibili 317
AF - Africa 174
OC - Oceania 89
Totale 33.276
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Nazione #
US - Stati Uniti d'America 14.546
RU - Federazione Russa 2.959
IT - Italia 2.392
HK - Hong Kong 1.781
SG - Singapore 1.667
CN - Cina 1.626
PL - Polonia 893
BR - Brasile 847
SE - Svezia 812
VN - Vietnam 772
IE - Irlanda 711
KR - Corea 539
DE - Germania 399
FR - Francia 318
FI - Finlandia 289
IN - India 238
GB - Regno Unito 188
CA - Canada 171
BD - Bangladesh 153
UA - Ucraina 95
CH - Svizzera 93
JP - Giappone 88
AU - Australia 86
NL - Olanda 86
AR - Argentina 85
ID - Indonesia 84
JO - Giordania 82
TR - Turchia 71
MX - Messico 64
EC - Ecuador 50
IQ - Iraq 44
ES - Italia 43
AT - Austria 36
ZA - Sudafrica 36
CI - Costa d'Avorio 34
BE - Belgio 33
CO - Colombia 29
SA - Arabia Saudita 19
MA - Marocco 18
PK - Pakistan 18
NG - Nigeria 17
PY - Paraguay 17
JM - Giamaica 16
IR - Iran 15
VE - Venezuela 15
AE - Emirati Arabi Uniti 14
GR - Grecia 14
AZ - Azerbaigian 11
CL - Cile 11
CZ - Repubblica Ceca 11
PH - Filippine 11
UZ - Uzbekistan 11
BJ - Benin 10
DK - Danimarca 10
EG - Egitto 10
MY - Malesia 10
CM - Camerun 9
IL - Israele 9
KE - Kenya 9
PT - Portogallo 9
TW - Taiwan 9
UY - Uruguay 9
BG - Bulgaria 8
CR - Costa Rica 8
LT - Lituania 8
PE - Perù 8
RO - Romania 8
GT - Guatemala 7
KZ - Kazakistan 7
PR - Porto Rico 7
TN - Tunisia 7
NO - Norvegia 6
DZ - Algeria 5
HN - Honduras 5
HU - Ungheria 5
SC - Seychelles 5
SN - Senegal 5
TH - Thailandia 5
TT - Trinidad e Tobago 5
BO - Bolivia 4
BS - Bahamas 4
GE - Georgia 4
NP - Nepal 4
RS - Serbia 4
SV - El Salvador 4
BB - Barbados 3
BY - Bielorussia 3
DO - Repubblica Dominicana 3
EE - Estonia 3
KG - Kirghizistan 3
LB - Libano 3
ML - Mali 3
OM - Oman 3
PA - Panama 3
QA - Qatar 3
SK - Slovacchia (Repubblica Slovacca) 3
AD - Andorra 2
AL - Albania 2
ET - Etiopia 2
EU - Europa 2
Totale 32.926
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Città #
Santa Clara 3.314
Ashburn 1.640
Hong Kong 1.634
Singapore 1.231
Fairfield 1.207
Warsaw 879
Dublin 711
Chandler 673
San Jose 553
Woodbridge 546
Seattle 532
Seoul 517
Houston 456
Cambridge 441
Milan 433
Florence 405
Wilmington 376
Hefei 362
Ann Arbor 313
Beijing 311
Ho Chi Minh City 222
Lawrence 220
Council Bluffs 219
Altamura 200
Rome 200
Jacksonville 197
The Dalles 180
Los Angeles 178
Hanoi 172
Princeton 167
Lauterbourg 166
Moscow 160
Dallas 151
Buffalo 148
Mumbai 141
Phoenix 114
Munich 103
Helsinki 100
New York 97
Medford 96
Boston 95
Boardman 89
Melbourne 84
São Paulo 84
Bern 81
Tokyo 70
Shanghai 69
Turku 65
San Diego 64
Kent 59
Dong Ket 58
Naples 57
Jakarta 56
Clifton 54
Paris 48
Turin 47
Elk Grove Village 46
Chicago 43
Lappeenranta 43
Haiphong 42
Toronto 40
Frankfurt am Main 39
Bologna 37
Atlanta 35
Rio de Janeiro 35
Abidjan 34
Norwalk 34
Redondo Beach 34
Izmir 33
Bremen 32
Brussels 30
Orem 30
Da Nang 29
London 29
Falls Church 28
Vienna 27
Montreal 25
Palermo 24
Andover 22
Barcelona 21
Hillsboro 21
Belo Horizonte 20
Guangzhou 20
Biên Hòa 19
Brooklyn 19
Johannesburg 19
Miano 19
Padova 19
Bengaluru 18
Chennai 18
Abuja 17
Camden 17
Nuremberg 17
Yubileyny 17
Baghdad 16
Stockholm 16
Venice 16
West Jordan 16
Catania 15
Columbus 15
Totale 21.991
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Nome #
Regulation of HuR structure and function by dihydrotanshinone-I 1.023
1 H-detected solid-state NMR of proteins entrapped in bioinspired silica: A new tool for biomaterials characterization 732
Seed amplification assays for diagnosing synucleinopathies: The issue of influencing factors 635
Persistent contrast enhancement by sterically stabilized paramagnetic liposomes in murine melanoma. 308
High-Resolution Solid-State NMR Characterization of Ligand Binding to a Protein Immobilized in a Silica Matrix 303
Long-range paramagnetic NMR data can provide a closer look on metal coordination in metalloproteins 291
Characterization of the Conjugation Pattern in Large Polysaccharide-Protein Conjugates by NMR Spectroscopy 278
Acido Ialuronico funzionalizzato 274
Characterization of PEGylated Asparaginase: New Opportunities from NMR Analysis of Large PEGylated Therapeutics 266
H-1 NMRD profiles of diamagnetic proteins: a model-free analysis 263
Aggregation kinetics of the Aβ1-40 peptide monitored by NMR 257
A small heterobifunctional ligand provides stable and water dispersible core-shell CdSe/ZnS quantum dots (QDs) 247
G-triplex structure and formation propensity 245
Integrative Approaches in Structural Biology: A More Complete Picture from the Combination of Individual Techniques 245
Real-Time Insights into Biological Events: In-Cell Processes and Protein-Ligand Interactions 244
Lipoyl-Homotaurine Derivative (ADM_12) Reverts Oxaliplatin-Induced Neuropathy and Reduces Cancer Cells Malignancy by Inhibiting Carbonic Anhydrase IX (CAIX) 240
AZA-Tanshinone derivatives, process for their preparation and their use in therapy 234
Active-Site Targeting Paramagnetic Probe for Matrix Metalloproteinases 232
Biomolecular NMR at 1.2 GHz 231
Atomic structural details of a protein grafted onto gold nanoparticles 230
NMR study of the secondary structure and biopharmaceutical formulation of an active branched antimicrobial peptide 230
Bilayer Membrane Modulation of Membrane Type 1 Matrix Metalloproteinase (MT1-MMP) Structure and Proteolytic Activity 229
The G-Triplex DNA 228
Epitope Mapping and Binding Assessment by Solid-State NMR Provide a Way for the Development of Biologics under the Quality by Design Paradigm 225
Engineering l-asparaginase for spontaneous formation of calcium phosphate bioinspired microreactors. 225
A protocol to automatically calculate homo-oligomeric protein structures through the integration of evolutionary constraints and NMR ambiguous contacts 225
Structural characterization of a protein adsorbed on aluminum hydroxide adjuvant in vaccine formulation 218
Solid-State NMR of PEGylated Proteins 215
Dissecting the Interactions between Human Serum Albumin and α-Synuclein: New Insights on the Factors Influencing α-Synuclein Aggregation in Biological Fluids 211
Biosilica and bioinspired silica studied by solid-state NMR 210
A Divalent PAMAM-Based Matrix Metalloproteinase/Carbonic Anhydrase Inhibitor for the Treatment of Dry Eye Syndrome 209
Insights into telomeric G-quadruplex DNA recognition by HMGB1 protein 209
A Highly Soluble Matrix Metalloproteinase-9 Inhibitor for Potential Treatment of Dry Eye Syndrome 208
NMR of sedimented, fibrillized, silica-entrapped and microcrystalline (metallo)proteins 208
Atomic-Level Quality Assessment of Enzymes Encapsulated in Bioinspired Silica 208
Interfering with HuR-RNA Interaction: Design, Synthesis and Biological Characterization of Tanshinone Mimics as Novel, Effective HuR Inhibitors 207
A Structurally Simple Vaccine Candidate Reduces Progression and Dissemination of Triple-Negative Breast Cancer 207
Exploring the subtleties of drug-receptor interactions: The case of matrix metalloproteinases 206
Simultaneous Targeting of RGD-Integrins and Dual Murine Double Minute Proteins in Glioblastoma Multiforme 205
Algal autolysate medium to label proteins for NMR in mammalian cells 205
In situ AP/MALDI-MS characterization of anchored matrix metalloproteinases 204
Functionalized Hyaluronic Acid 203
A new NT4 peptide-based drug delivery system for cancer treatment 202
Structural basis of serine/threonine phosphatase inhibition by the archetypal small molecules cantharidin and norcantharidin 201
Theoretical and experimental studies on the interaction of biphenyl ligands with human and murine PD-L1: Up-to-date clues for drug design 199
Combining Solid-State NMR with Structural and Biophysical Techniques to Design Challenging Protein-Drug Conjugates 199
Discovery of a New Class of Potent MMP Inhibitors by Structure-Based Optimization of the Arylsulfonamide Scaffold 198
"Four-dimensional" protein structures: Examples from metalloproteins 197
Biotin-tagged probes for MMP expression and activation: design, synthesis, and binding properties 197
Structural basis for matrix metalloproteinase 1-catalyzed collagenolysis 196
1H NMR Relaxometric Study of Chitosan-Based Nanogels Containing Mono- And Bis-Hydrated Gd(III) Chelates: Clues for MRI Probes of Improved Sensitivity 196
A new methodology for monitoring the activity of cdMMP-12 anchored and freeze-dried on Au(111) 196
Paramagnetic metal ions in ligand screening: The Co-II matrix metalloproteinase 12 195
1H NMRD dispersions of porous media: a model-free analysis 195
Automated Determination of Nuclear Magnetic Resonance Chemical Shift Perturbations in Ligand Screening Experiments: The PICASSO Web Server 195
Targeting Matrix Metalloproteinases: Design of a Bifunctional Inhibitor for Presentation by Tumour-Associated Galectins 194
Biosilica-Entrapped Enzymes Studied by Using Dynamic Nuclear-Polarization-Enhanced High-Field NMR Spectroscopy 194
Solid-state NMR of matrix metalloproteinase 12: An approach complementary to solution NMR 193
Activity of anchored human matrix metalloproteinase-1 catalytic domain on Au(111) surfaces monitored by ESI-MS 191
Entropic contribution to the linking coefficient in fragment based drug design: a case study. 191
Conformational variability of matrix metalloproteinases: beyond a single 3D structure 191
Metal centers in biomolecular solid-state NMR 191
Snapshots of the reaction mechanism of matrix metalloproteinases 188
Differences in Dynamics between Crosslinked and Non-Crosslinked Hyaluronates Measured by using Fast Field-Cycling Relaxometry 188
Computer-Aided Identification and Lead Optimization of Dual Murine Double Minute 2 and 4 Binders: Structure-Activity Relationship Studies and Pharmacological Activity 188
Crystal structure of the catalytic domain of human matrix metalloproteinase 10 187
Mixing Aβ(1-40) and Aβ(1-42) peptides generates unique amyloid fibrils 187
Substrate specificities of matrix metalloproteinase 1 in PAR-1 exodomain proteolysis 186
Molecular Insights into O-Linked Sialoglycans Recognition by the Siglec-Like SLBR-N (SLBRUB10712) of Streptococcus gordonii 184
Water-based ligand screening for paramagnetic metalloproteins 184
A high-resolution view of the coordination environment in a paramagnetic metalloprotein from its magnetic properties 183
A high-affinity carbohydrate-containing inhibitor of matrix metalloproteinases 182
Structure-Based Approach to Nanomolar, Water Soluble Matrix Metalloproteinases Inhibitors (MMPIs) 182
Nanoparticles for the multivalent presentation of a TnThr mimetic and as tool for solid state NMR coating investigation 181
Combining in silico tools and NMR data to validate protein-ligand structural models: Application to matrix metalloproteinases 180
Unraveling Hidden Regulatory Sites in Structurally Homologous Metalloproteases 180
Solution structure and dynamics of human S100A14 179
Synthesis and binding monitoring of a new nanomolar PAMAM-based matrix metalloproteinases inhibitor (MMPIs) 178
Functionalized Hyaluronic Acid for “In Situ” Matrix Metalloproteinase Inhibition: A Bioactive Material to Treat the Dry Eye Sydrome 177
Identification and Characterization of an RRM-Containing, RNA Binding Protein in Acinetobacter baumannii 176
Large Protein Assemblies for High-Relaxivity Contrast Agents: The Case of Gadolinium-Labeled Asparaginase 175
Cerebrospinal fluid lipoproteins inhibit α-synuclein aggregation by interacting with oligomeric species in seed amplification assays 174
NMR characterization of the C-terminal tail of full-length RAGE in a membrane mimicking environment 172
Sulfonamide-functionalized gadolinium DTPA complexes as possible contrast agents for MRI: A relaxometric investigation 171
Quantum Dot-Based Probes for Labeling and Imaging of Cells that Express Matrix Metalloproteinases 170
Paramagnetic NMR as a new tool in structural biology 169
Design in silico, synthesis and binding evaluation of a carbohydrate-based scaffold for structurally novel inhibitors of matrix metalloproteinases 168
Molecular Determinants of a Selective Matrix Metalloprotease-12 Inhibitor: Insights from Crystallography and Thermodynamic Studies 168
Insights into Domain-Domain Motions in Proteins and RNA from Solution NMR 168
CXCR4 antagonism sensitizes cancer cells to novel indole-based MDM2/4 inhibitors in glioblastoma multiforme 168
HuR-targeted agents: An insight into medicinal chemistry, biophysical, computational studies and pharmacological effects on cancer models 167
A calix[4]arene Gd-III complex endowed with high stability, relaxivity, and binding affinity to serum albumin 167
Evidence of reciprocal reorientation of the catalytic and hemopexin-like domains of full-length MMP-12 167
Conformational freedom of metalloproteins revealed by paramagnetism-assisted NMR 167
SSNMR of biosilica-entrapped enzymes permits an easy assessment of preservation of native conformation in atomic detail 167
alpha ',alpha '-dioxothiones, III Regio- and stereoselective ene and tandem "ene-cycloaddition'' reactions of 2,4-dioxopentane-3-thione 166
NMR quality control of fragment libraries for screening 166
Elucidating the concentration-dependent effects of thiocyanate binding to carbonic anhydrase 163
Paramagnetic Properties of a Crystalline Iron-Sulfur Protein by Magic-Angle Spinning NMR Spectroscopy 163
Site-Selective Functionalized PD-1 Mutant for a Modular Immunological Activity against Cancer Cells 162
Totale 22.032
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Categoria #
all - tutte 91.117
article - articoli 0
book - libri 0
conference - conferenze 0
curatela - curatele 0
other - altro 0
patent - brevetti 0
selected - selezionate 0
volume - volumi 0
Totale 91.117
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Totale Lug Ago Sett Ott Nov Dic Gen Feb Mar Apr Mag Giu
2021/20221.096 0 0 110 54 61 56 61 103 87 52 201 311
2022/20233.200 293 620 186 270 219 561 420 140 271 36 79 105
2023/20241.286 70 135 174 77 84 198 52 217 26 119 75 59
2024/20259.029 305 834 639 1.337 2.422 1.462 200 625 309 182 346 368
2025/202611.078 900 2.275 967 1.049 1.073 387 1.101 507 610 593 357 1.259
2026/20271.195 449 296 450 0 0 0 0 0 0 0 0 0
Totale 33.276