FRAGAI, MARCO
 Distribuzione geografica
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Continente #
NA - Nord America 12.236
EU - Europa 7.793
AS - Asia 5.851
SA - Sud America 964
AF - Africa 125
OC - Oceania 86
Continente sconosciuto - Info sul continente non disponibili 2
Totale 27.057
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Nazione #
US - Stati Uniti d'America 12.098
RU - Federazione Russa 2.953
HK - Hong Kong 1.743
SG - Singapore 1.310
CN - Cina 1.250
IT - Italia 1.149
PL - Polonia 883
BR - Brasile 781
SE - Svezia 763
IE - Irlanda 710
KR - Corea 537
VN - Vietnam 388
DE - Germania 364
FI - Finlandia 241
IN - India 202
GB - Regno Unito 171
FR - Francia 121
UA - Ucraina 89
CH - Svizzera 88
AU - Australia 84
ID - Indonesia 78
JO - Giordania 76
AR - Argentina 74
NL - Olanda 73
TR - Turchia 68
CA - Canada 66
MX - Messico 46
EC - Ecuador 42
JP - Giappone 36
ES - Italia 35
AT - Austria 34
BE - Belgio 33
CI - Costa d'Avorio 33
ZA - Sudafrica 30
BD - Bangladesh 26
IQ - Iraq 21
CO - Colombia 18
PY - Paraguay 16
GR - Grecia 13
IR - Iran 13
SA - Arabia Saudita 13
MA - Marocco 11
BJ - Benin 10
CL - Cile 10
AZ - Azerbaigian 9
CM - Camerun 9
CZ - Repubblica Ceca 9
DK - Danimarca 9
AE - Emirati Arabi Uniti 8
BG - Bulgaria 8
IL - Israele 8
PK - Pakistan 8
RO - Romania 8
UZ - Uzbekistan 8
VE - Venezuela 8
MY - Malesia 7
PT - Portogallo 7
TW - Taiwan 7
EG - Egitto 6
NO - Norvegia 6
PE - Perù 6
TN - Tunisia 6
KE - Kenya 5
KZ - Kazakistan 5
UY - Uruguay 5
GE - Georgia 4
JM - Giamaica 4
LT - Lituania 4
SC - Seychelles 4
SN - Senegal 4
BO - Bolivia 3
BY - Bielorussia 3
CR - Costa Rica 3
DO - Repubblica Dominicana 3
DZ - Algeria 3
EE - Estonia 3
OM - Oman 3
PA - Panama 3
PH - Filippine 3
SV - El Salvador 3
TT - Trinidad e Tobago 3
EU - Europa 2
GT - Guatemala 2
HR - Croazia 2
HU - Ungheria 2
KG - Kirghizistan 2
KW - Kuwait 2
LB - Libano 2
LI - Liechtenstein 2
MN - Mongolia 2
NP - Nepal 2
PR - Porto Rico 2
QA - Qatar 2
RS - Serbia 2
SK - Slovacchia (Repubblica Slovacca) 2
TJ - Tagikistan 2
AD - Andorra 1
AL - Albania 1
AO - Angola 1
BB - Barbados 1
Totale 27.039
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Città #
Santa Clara 3.243
Hong Kong 1.607
Fairfield 1.207
Ashburn 1.021
Singapore 902
Warsaw 877
Dublin 710
Chandler 673
Woodbridge 546
Seattle 528
Seoul 517
Houston 452
Cambridge 439
Wilmington 375
Hefei 361
Florence 345
Ann Arbor 307
Beijing 295
Lawrence 220
Altamura 199
Jacksonville 194
Princeton 167
Moscow 159
Mumbai 135
Buffalo 134
Dallas 133
Los Angeles 124
Ho Chi Minh City 113
Munich 103
Medford 96
Boston 92
Milan 89
Melbourne 83
Bern 81
Boardman 79
São Paulo 73
The Dalles 73
Hanoi 68
Turku 65
New York 62
Helsinki 60
San Diego 60
Kent 59
Dong Ket 58
Shanghai 56
Jakarta 55
Clifton 54
Paris 36
Lappeenranta 35
Redondo Beach 34
Abidjan 33
Izmir 33
Norwalk 33
Atlanta 32
Bremen 32
Brussels 30
Chicago 30
Rio de Janeiro 29
Falls Church 28
Toronto 26
London 25
Tokyo 25
Vienna 25
Rome 23
Andover 22
Hillsboro 21
Barcelona 20
Belo Horizonte 20
Haiphong 20
Naples 19
Padova 19
Bengaluru 18
Frankfurt am Main 18
Camden 17
Yubileyny 17
Johannesburg 16
West Jordan 16
Falkenstein 15
Guayaquil 15
Stockholm 15
Biên Hòa 14
Brooklyn 14
Montreal 14
Phoenix 14
Redmond 14
Redwood City 14
Turin 14
Brasília 12
Council Bluffs 12
Da Nang 12
Nuremberg 12
Campinas 11
Gothenburg 11
Poplar 11
Bologna 10
Cotonou 10
Curitiba 10
Napoli 10
Philadelphia 10
Porto Alegre 10
Totale 18.385
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Nome #
Regulation of HuR structure and function by dihydrotanshinone-I 991
1 H-detected solid-state NMR of proteins entrapped in bioinspired silica: A new tool for biomaterials characterization 684
Seed amplification assays for diagnosing synucleinopathies: The issue of influencing factors 562
Persistent contrast enhancement by sterically stabilized paramagnetic liposomes in murine melanoma. 272
High-Resolution Solid-State NMR Characterization of Ligand Binding to a Protein Immobilized in a Silica Matrix 262
Characterization of the Conjugation Pattern in Large Polysaccharide-Protein Conjugates by NMR Spectroscopy 246
Long-range paramagnetic NMR data can provide a closer look on metal coordination in metalloproteins 242
Acido Ialuronico funzionalizzato 238
H-1 NMRD profiles of diamagnetic proteins: a model-free analysis 235
Real-Time Insights into Biological Events: In-Cell Processes and Protein-Ligand Interactions 233
Aggregation kinetics of the Aβ1-40 peptide monitored by NMR 224
G-triplex structure and formation propensity 216
Lipoyl-Homotaurine Derivative (ADM_12) Reverts Oxaliplatin-Induced Neuropathy and Reduces Cancer Cells Malignancy by Inhibiting Carbonic Anhydrase IX (CAIX) 216
Integrative Approaches in Structural Biology: A More Complete Picture from the Combination of Individual Techniques 212
Characterization of PEGylated Asparaginase: New Opportunities from NMR Analysis of Large PEGylated Therapeutics 210
Bilayer Membrane Modulation of Membrane Type 1 Matrix Metalloproteinase (MT1-MMP) Structure and Proteolytic Activity 204
Atomic structural details of a protein grafted onto gold nanoparticles 202
A small heterobifunctional ligand provides stable and water dispersible core-shell CdSe/ZnS quantum dots (QDs) 202
The G-Triplex DNA 201
Engineering l-asparaginase for spontaneous formation of calcium phosphate bioinspired microreactors. 201
AZA-Tanshinone derivatives, process for their preparation and their use in therapy 201
Biomolecular NMR at 1.2 GHz 195
Structural characterization of a protein adsorbed on aluminum hydroxide adjuvant in vaccine formulation 195
NMR study of the secondary structure and biopharmaceutical formulation of an active branched antimicrobial peptide 193
Active-Site Targeting Paramagnetic Probe for Matrix Metalloproteinases 190
A protocol to automatically calculate homo-oligomeric protein structures through the integration of evolutionary constraints and NMR ambiguous contacts 190
Dissecting the Interactions between Human Serum Albumin and α-Synuclein: New Insights on the Factors Influencing α-Synuclein Aggregation in Biological Fluids 184
Solid-State NMR of PEGylated Proteins 182
A Highly Soluble Matrix Metalloproteinase-9 Inhibitor for Potential Treatment of Dry Eye Syndrome 181
NMR of sedimented, fibrillized, silica-entrapped and microcrystalline (metallo)proteins 181
Functionalized Hyaluronic Acid 181
Insights into telomeric G-quadruplex DNA recognition by HMGB1 protein 179
Biosilica and bioinspired silica studied by solid-state NMR 179
Algal autolysate medium to label proteins for NMR in mammalian cells 179
Exploring the subtleties of drug-receptor interactions: The case of matrix metalloproteinases 178
Simultaneous Targeting of RGD-Integrins and Dual Murine Double Minute Proteins in Glioblastoma Multiforme 178
Epitope Mapping and Binding Assessment by Solid-State NMR Provide a Way for the Development of Biologics under the Quality by Design Paradigm 176
A Divalent PAMAM-Based Matrix Metalloproteinase/Carbonic Anhydrase Inhibitor for the Treatment of Dry Eye Syndrome 175
Atomic-Level Quality Assessment of Enzymes Encapsulated in Bioinspired Silica 175
In situ AP/MALDI-MS characterization of anchored matrix metalloproteinases 174
Structural basis for matrix metalloproteinase 1-catalyzed collagenolysis 174
Paramagnetic metal ions in ligand screening: The Co-II matrix metalloproteinase 12 173
Theoretical and experimental studies on the interaction of biphenyl ligands with human and murine PD-L1: Up-to-date clues for drug design 172
Combining Solid-State NMR with Structural and Biophysical Techniques to Design Challenging Protein-Drug Conjugates 172
Discovery of a New Class of Potent MMP Inhibitors by Structure-Based Optimization of the Arylsulfonamide Scaffold 171
Substrate specificities of matrix metalloproteinase 1 in PAR-1 exodomain proteolysis 170
A Structurally Simple Vaccine Candidate Reduces Progression and Dissemination of Triple-Negative Breast Cancer 170
Crystal structure of the catalytic domain of human matrix metalloproteinase 10 169
Activity of anchored human matrix metalloproteinase-1 catalytic domain on Au(111) surfaces monitored by ESI-MS 167
Biotin-tagged probes for MMP expression and activation: design, synthesis, and binding properties 167
A new NT4 peptide-based drug delivery system for cancer treatment 167
1H NMRD dispersions of porous media: a model-free analysis 166
A new methodology for monitoring the activity of cdMMP-12 anchored and freeze-dried on Au(111) 166
Conformational variability of matrix metalloproteinases: beyond a single 3D structure 165
Synthesis and binding monitoring of a new nanomolar PAMAM-based matrix metalloproteinases inhibitor (MMPIs) 164
Metal centers in biomolecular solid-state NMR 164
Computer-Aided Identification and Lead Optimization of Dual Murine Double Minute 2 and 4 Binders: Structure-Activity Relationship Studies and Pharmacological Activity 164
Snapshots of the reaction mechanism of matrix metalloproteinases 163
Entropic contribution to the linking coefficient in fragment based drug design: a case study. 162
Solid-state NMR of matrix metalloproteinase 12: An approach complementary to solution NMR 162
Structural basis of serine/threonine phosphatase inhibition by the archetypal small molecules cantharidin and norcantharidin 161
Biosilica-Entrapped Enzymes Studied by Using Dynamic Nuclear-Polarization-Enhanced High-Field NMR Spectroscopy 161
Automated Determination of Nuclear Magnetic Resonance Chemical Shift Perturbations in Ligand Screening Experiments: The PICASSO Web Server 160
Interfering with HuR-RNA Interaction: Design, Synthesis and Biological Characterization of Tanshinone Mimics as Novel, Effective HuR Inhibitors 158
Mixing Aβ(1-40) and Aβ(1-42) peptides generates unique amyloid fibrils 157
"Four-dimensional" protein structures: Examples from metalloproteins 156
Solution structure and dynamics of human S100A14 155
Combining in silico tools and NMR data to validate protein-ligand structural models: Application to matrix metalloproteinases 154
Targeting Matrix Metalloproteinases: Design of a Bifunctional Inhibitor for Presentation by Tumour-Associated Galectins 153
Structure-Based Approach to Nanomolar, Water Soluble Matrix Metalloproteinases Inhibitors (MMPIs) 151
Water-based ligand screening for paramagnetic metalloproteins 149
Elucidating the concentration-dependent effects of thiocyanate binding to carbonic anhydrase 148
Evidence of reciprocal reorientation of the catalytic and hemopexin-like domains of full-length MMP-12 148
Quantum Dot-Based Probes for Labeling and Imaging of Cells that Express Matrix Metalloproteinases 148
Functionalized Hyaluronic Acid for “In Situ” Matrix Metalloproteinase Inhibition: A Bioactive Material to Treat the Dry Eye Sydrome 147
A high-affinity carbohydrate-containing inhibitor of matrix metalloproteinases 147
Unraveling Hidden Regulatory Sites in Structurally Homologous Metalloproteases 147
Identification and Characterization of an RRM-Containing, RNA Binding Protein in Acinetobacter baumannii 146
Differences in Dynamics between Crosslinked and Non-Crosslinked Hyaluronates Measured by using Fast Field-Cycling Relaxometry 146
HuR-targeted agents: An insight into medicinal chemistry, biophysical, computational studies and pharmacological effects on cancer models 145
Molecular Determinants of a Selective Matrix Metalloprotease-12 Inhibitor: Insights from Crystallography and Thermodynamic Studies 144
NMR characterization of the C-terminal tail of full-length RAGE in a membrane mimicking environment 144
Large Protein Assemblies for High-Relaxivity Contrast Agents: The Case of Gadolinium-Labeled Asparaginase 143
Design in silico, synthesis and binding evaluation of a carbohydrate-based scaffold for structurally novel inhibitors of matrix metalloproteinases 143
Molecular Insights into O-Linked Sialoglycans Recognition by the Siglec-Like SLBR-N (SLBRUB10712) of Streptococcus gordonii 142
alpha ',alpha '-dioxothiones, III Regio- and stereoselective ene and tandem "ene-cycloaddition'' reactions of 2,4-dioxopentane-3-thione 141
SSNMR of biosilica-entrapped enzymes permits an easy assessment of preservation of native conformation in atomic detail 141
Paramagnetic Properties of a Crystalline Iron-Sulfur Protein by Magic-Angle Spinning NMR Spectroscopy 141
CXCR4 antagonism sensitizes cancer cells to novel indole-based MDM2/4 inhibitors in glioblastoma multiforme 141
A calix[4]arene Gd-III complex endowed with high stability, relaxivity, and binding affinity to serum albumin 140
Insights into Domain-Domain Motions in Proteins and RNA from Solution NMR 140
The catalytic domain of MMP-1 studied through tagged lanthanides 140
A high-resolution view of the coordination environment in a paramagnetic metalloprotein from its magnetic properties 139
Nanoparticles for the multivalent presentation of a TnThr mimetic and as tool for solid state NMR coating investigation 139
Paramagnetic NMR as a new tool in structural biology 138
How Do Nuclei Couple to the Magnetic Moment of a Paramagnetic Center? A New Theory at the Gauntlet of the Experiments 137
Conformational freedom of metalloproteins revealed by paramagnetism-assisted NMR 136
1H NMR Relaxometric Study of Chitosan-Based Nanogels Containing Mono- And Bis-Hydrated Gd(III) Chelates: Clues for MRI Probes of Improved Sensitivity 136
Probing the interaction of distamycin A with S100β: the "unexpected" ability of S100β to bind to DNA-binding ligands 136
Protein Glycosylation through Sulfur Fluoride Exchange (SuFEx) Chemistry: The Key Role of a Fluorosulfate Thiolactoside 135
Totale 18.900
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Categoria #
all - tutte 74.193
article - articoli 0
book - libri 0
conference - conferenze 0
curatela - curatele 0
other - altro 0
patent - brevetti 0
selected - selezionate 0
volume - volumi 0
Totale 74.193
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Totale Lug Ago Sett Ott Nov Dic Gen Feb Mar Apr Mag Giu
2020/20211.258 0 0 0 0 0 212 73 158 199 364 110 142
2021/20221.227 52 79 110 54 61 56 61 103 87 52 201 311
2022/20233.200 293 620 186 270 219 561 420 140 271 36 79 105
2023/20241.286 70 135 174 77 84 198 52 217 26 119 75 59
2024/20259.029 305 834 639 1.337 2.422 1.462 200 625 309 182 346 368
2025/20266.356 900 2.275 967 1.049 1.073 92 0 0 0 0 0 0
Totale 27.359