FRAGAI, MARCO
 Distribuzione geografica
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Continente #
NA - Nord America 15.390
EU - Europa 9.539
AS - Asia 7.295
SA - Sud America 1.091
Continente sconosciuto - Info sul continente non disponibili 319
AF - Africa 175
OC - Oceania 89
Totale 33.898
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Nazione #
US - Stati Uniti d'America 15.065
RU - Federazione Russa 2.959
IT - Italia 2.454
HK - Hong Kong 1.780
SG - Singapore 1.662
CN - Cina 1.622
PL - Polonia 892
BR - Brasile 854
SE - Svezia 811
VN - Vietnam 770
IE - Irlanda 712
KR - Corea 539
DE - Germania 406
FR - Francia 312
FI - Finlandia 288
IN - India 236
GB - Regno Unito 197
CA - Canada 180
BD - Bangladesh 141
CH - Svizzera 95
UA - Ucraina 95
AR - Argentina 88
NL - Olanda 87
AU - Australia 86
ID - Indonesia 86
JP - Giappone 86
JO - Giordania 82
TR - Turchia 72
MX - Messico 65
EC - Ecuador 52
ES - Italia 50
IQ - Iraq 44
AT - Austria 38
ZA - Sudafrica 36
CI - Costa d'Avorio 34
BE - Belgio 33
CO - Colombia 30
SA - Arabia Saudita 19
MA - Marocco 18
NG - Nigeria 17
PK - Pakistan 17
PY - Paraguay 17
JM - Giamaica 16
VE - Venezuela 16
AE - Emirati Arabi Uniti 15
GR - Grecia 14
IR - Iran 14
AZ - Azerbaigian 12
CL - Cile 12
PH - Filippine 12
TW - Taiwan 12
CZ - Repubblica Ceca 11
MY - Malesia 11
UZ - Uzbekistan 11
BJ - Benin 10
DK - Danimarca 10
EG - Egitto 10
CM - Camerun 9
CR - Costa Rica 9
IL - Israele 9
KE - Kenya 9
PT - Portogallo 9
UY - Uruguay 9
BG - Bulgaria 8
HN - Honduras 8
LT - Lituania 8
PE - Perù 8
PR - Porto Rico 8
RO - Romania 8
GT - Guatemala 7
KZ - Kazakistan 7
TN - Tunisia 7
TT - Trinidad e Tobago 7
NO - Norvegia 6
SC - Seychelles 6
DZ - Algeria 5
HU - Ungheria 5
RS - Serbia 5
SN - Senegal 5
TH - Thailandia 5
BO - Bolivia 4
BS - Bahamas 4
EE - Estonia 4
GE - Georgia 4
NP - Nepal 4
SV - El Salvador 4
BB - Barbados 3
BY - Bielorussia 3
DO - Repubblica Dominicana 3
KG - Kirghizistan 3
LB - Libano 3
ML - Mali 3
OM - Oman 3
PA - Panama 3
QA - Qatar 3
SK - Slovacchia (Repubblica Slovacca) 3
AD - Andorra 2
AL - Albania 2
ET - Etiopia 2
EU - Europa 2
Totale 33.542
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Città #
Santa Clara 3.320
Ashburn 1.679
Hong Kong 1.634
Singapore 1.226
Fairfield 1.208
Warsaw 879
Dublin 712
Chandler 674
San Jose 556
Woodbridge 548
Seattle 536
Seoul 517
Houston 461
Cambridge 441
Milan 441
Florence 412
Wilmington 376
Hefei 362
Ann Arbor 313
Beijing 311
Council Bluffs 227
Ho Chi Minh City 222
Lawrence 220
Rome 206
Altamura 200
Jacksonville 200
Los Angeles 189
The Dalles 180
Hanoi 171
Princeton 167
Lauterbourg 165
Moscow 160
Dallas 153
Buffalo 150
Mumbai 141
Phoenix 120
Munich 103
Helsinki 101
New York 100
Boston 96
Medford 96
Boardman 91
Chicago 85
Melbourne 84
São Paulo 83
Bern 81
Tokyo 69
Shanghai 68
San Diego 67
Turku 65
Kent 59
Dong Ket 58
Jakarta 56
Naples 56
Clifton 54
Turin 48
Elk Grove Village 47
Paris 46
Toronto 43
Bologna 41
Haiphong 41
Lappeenranta 41
Frankfurt am Main 40
Atlanta 38
Rio de Janeiro 35
Abidjan 34
Norwalk 34
Redondo Beach 34
Izmir 33
Bremen 32
Brussels 30
Orem 30
Da Nang 29
London 29
Vienna 29
Falls Church 28
Montreal 26
Brooklyn 25
Palermo 24
Andover 22
Hillsboro 22
Barcelona 21
Miano 21
Philadelphia 21
Belo Horizonte 20
Guangzhou 20
Biên Hòa 19
Figino 19
Johannesburg 19
Padova 19
Bengaluru 18
Brasília 18
Chennai 18
Nuremberg 18
Abuja 17
Camden 17
Denver 17
Verona 17
Yubileyny 17
Baghdad 16
Totale 22.182
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Nome #
Regulation of HuR structure and function by dihydrotanshinone-I 1.025
1 H-detected solid-state NMR of proteins entrapped in bioinspired silica: A new tool for biomaterials characterization 735
Seed amplification assays for diagnosing synucleinopathies: The issue of influencing factors 641
Persistent contrast enhancement by sterically stabilized paramagnetic liposomes in murine melanoma. 310
High-Resolution Solid-State NMR Characterization of Ligand Binding to a Protein Immobilized in a Silica Matrix 307
Long-range paramagnetic NMR data can provide a closer look on metal coordination in metalloproteins 295
Characterization of the Conjugation Pattern in Large Polysaccharide-Protein Conjugates by NMR Spectroscopy 282
Acido Ialuronico funzionalizzato 278
Characterization of PEGylated Asparaginase: New Opportunities from NMR Analysis of Large PEGylated Therapeutics 271
H-1 NMRD profiles of diamagnetic proteins: a model-free analysis 266
Aggregation kinetics of the Aβ1-40 peptide monitored by NMR 259
A small heterobifunctional ligand provides stable and water dispersible core-shell CdSe/ZnS quantum dots (QDs) 253
G-triplex structure and formation propensity 250
Integrative Approaches in Structural Biology: A More Complete Picture from the Combination of Individual Techniques 248
Lipoyl-Homotaurine Derivative (ADM_12) Reverts Oxaliplatin-Induced Neuropathy and Reduces Cancer Cells Malignancy by Inhibiting Carbonic Anhydrase IX (CAIX) 246
Real-Time Insights into Biological Events: In-Cell Processes and Protein-Ligand Interactions 245
Active-Site Targeting Paramagnetic Probe for Matrix Metalloproteinases 239
AZA-Tanshinone derivatives, process for their preparation and their use in therapy 237
Biomolecular NMR at 1.2 GHz 236
Atomic structural details of a protein grafted onto gold nanoparticles 234
NMR study of the secondary structure and biopharmaceutical formulation of an active branched antimicrobial peptide 233
The G-Triplex DNA 232
Bilayer Membrane Modulation of Membrane Type 1 Matrix Metalloproteinase (MT1-MMP) Structure and Proteolytic Activity 231
A protocol to automatically calculate homo-oligomeric protein structures through the integration of evolutionary constraints and NMR ambiguous contacts 229
Epitope Mapping and Binding Assessment by Solid-State NMR Provide a Way for the Development of Biologics under the Quality by Design Paradigm 227
Engineering l-asparaginase for spontaneous formation of calcium phosphate bioinspired microreactors. 226
A Divalent PAMAM-Based Matrix Metalloproteinase/Carbonic Anhydrase Inhibitor for the Treatment of Dry Eye Syndrome 219
Structural characterization of a protein adsorbed on aluminum hydroxide adjuvant in vaccine formulation 219
Solid-State NMR of PEGylated Proteins 217
Dissecting the Interactions between Human Serum Albumin and α-Synuclein: New Insights on the Factors Influencing α-Synuclein Aggregation in Biological Fluids 214
A Highly Soluble Matrix Metalloproteinase-9 Inhibitor for Potential Treatment of Dry Eye Syndrome 213
Atomic-Level Quality Assessment of Enzymes Encapsulated in Bioinspired Silica 213
Exploring the subtleties of drug-receptor interactions: The case of matrix metalloproteinases 213
Biosilica and bioinspired silica studied by solid-state NMR 213
A Structurally Simple Vaccine Candidate Reduces Progression and Dissemination of Triple-Negative Breast Cancer 211
Insights into telomeric G-quadruplex DNA recognition by HMGB1 protein 210
Algal autolysate medium to label proteins for NMR in mammalian cells 210
NMR of sedimented, fibrillized, silica-entrapped and microcrystalline (metallo)proteins 209
Interfering with HuR-RNA Interaction: Design, Synthesis and Biological Characterization of Tanshinone Mimics as Novel, Effective HuR Inhibitors 209
In situ AP/MALDI-MS characterization of anchored matrix metalloproteinases 208
A new NT4 peptide-based drug delivery system for cancer treatment 208
Functionalized Hyaluronic Acid for “In Situ” Matrix Metalloproteinase Inhibition: A Bioactive Material to Treat the Dry Eye Sydrome 207
Simultaneous Targeting of RGD-Integrins and Dual Murine Double Minute Proteins in Glioblastoma Multiforme 206
Structural basis of serine/threonine phosphatase inhibition by the archetypal small molecules cantharidin and norcantharidin 205
Functionalized Hyaluronic Acid 204
Combining Solid-State NMR with Structural and Biophysical Techniques to Design Challenging Protein-Drug Conjugates 203
Structural basis for matrix metalloproteinase 1-catalyzed collagenolysis 202
Discovery of a New Class of Potent MMP Inhibitors by Structure-Based Optimization of the Arylsulfonamide Scaffold 202
"Four-dimensional" protein structures: Examples from metalloproteins 201
Biosilica-Entrapped Enzymes Studied by Using Dynamic Nuclear-Polarization-Enhanced High-Field NMR Spectroscopy 201
Theoretical and experimental studies on the interaction of biphenyl ligands with human and murine PD-L1: Up-to-date clues for drug design 200
A new methodology for monitoring the activity of cdMMP-12 anchored and freeze-dried on Au(111) 200
Biotin-tagged probes for MMP expression and activation: design, synthesis, and binding properties 200
Paramagnetic metal ions in ligand screening: The Co-II matrix metalloproteinase 12 199
1H NMR Relaxometric Study of Chitosan-Based Nanogels Containing Mono- And Bis-Hydrated Gd(III) Chelates: Clues for MRI Probes of Improved Sensitivity 199
1H NMRD dispersions of porous media: a model-free analysis 198
Automated Determination of Nuclear Magnetic Resonance Chemical Shift Perturbations in Ligand Screening Experiments: The PICASSO Web Server 198
Targeting Matrix Metalloproteinases: Design of a Bifunctional Inhibitor for Presentation by Tumour-Associated Galectins 196
Activity of anchored human matrix metalloproteinase-1 catalytic domain on Au(111) surfaces monitored by ESI-MS 195
Solid-state NMR of matrix metalloproteinase 12: An approach complementary to solution NMR 195
Metal centers in biomolecular solid-state NMR 194
Entropic contribution to the linking coefficient in fragment based drug design: a case study. 193
Conformational variability of matrix metalloproteinases: beyond a single 3D structure 193
Computer-Aided Identification and Lead Optimization of Dual Murine Double Minute 2 and 4 Binders: Structure-Activity Relationship Studies and Pharmacological Activity 193
Differences in Dynamics between Crosslinked and Non-Crosslinked Hyaluronates Measured by using Fast Field-Cycling Relaxometry 192
Molecular Insights into O-Linked Sialoglycans Recognition by the Siglec-Like SLBR-N (SLBRUB10712) of Streptococcus gordonii 190
Snapshots of the reaction mechanism of matrix metalloproteinases 190
Crystal structure of the catalytic domain of human matrix metalloproteinase 10 190
Mixing Aβ(1-40) and Aβ(1-42) peptides generates unique amyloid fibrils 189
Water-based ligand screening for paramagnetic metalloproteins 188
Substrate specificities of matrix metalloproteinase 1 in PAR-1 exodomain proteolysis 187
A high-resolution view of the coordination environment in a paramagnetic metalloprotein from its magnetic properties 187
A high-affinity carbohydrate-containing inhibitor of matrix metalloproteinases 185
Structure-Based Approach to Nanomolar, Water Soluble Matrix Metalloproteinases Inhibitors (MMPIs) 184
Combining in silico tools and NMR data to validate protein-ligand structural models: Application to matrix metalloproteinases 184
Nanoparticles for the multivalent presentation of a TnThr mimetic and as tool for solid state NMR coating investigation 182
Synthesis and binding monitoring of a new nanomolar PAMAM-based matrix metalloproteinases inhibitor (MMPIs) 181
Unraveling Hidden Regulatory Sites in Structurally Homologous Metalloproteases 181
Solution structure and dynamics of human S100A14 181
Cerebrospinal fluid lipoproteins inhibit α-synuclein aggregation by interacting with oligomeric species in seed amplification assays 181
Identification and Characterization of an RRM-Containing, RNA Binding Protein in Acinetobacter baumannii 177
Large Protein Assemblies for High-Relaxivity Contrast Agents: The Case of Gadolinium-Labeled Asparaginase 176
NMR characterization of the C-terminal tail of full-length RAGE in a membrane mimicking environment 176
Design in silico, synthesis and binding evaluation of a carbohydrate-based scaffold for structurally novel inhibitors of matrix metalloproteinases 173
CXCR4 antagonism sensitizes cancer cells to novel indole-based MDM2/4 inhibitors in glioblastoma multiforme 173
A calix[4]arene Gd-III complex endowed with high stability, relaxivity, and binding affinity to serum albumin 172
Sulfonamide-functionalized gadolinium DTPA complexes as possible contrast agents for MRI: A relaxometric investigation 172
Evidence of reciprocal reorientation of the catalytic and hemopexin-like domains of full-length MMP-12 171
Molecular Determinants of a Selective Matrix Metalloprotease-12 Inhibitor: Insights from Crystallography and Thermodynamic Studies 171
Paramagnetic NMR as a new tool in structural biology 171
Quantum Dot-Based Probes for Labeling and Imaging of Cells that Express Matrix Metalloproteinases 171
HuR-targeted agents: An insight into medicinal chemistry, biophysical, computational studies and pharmacological effects on cancer models 170
alpha ',alpha '-dioxothiones, III Regio- and stereoselective ene and tandem "ene-cycloaddition'' reactions of 2,4-dioxopentane-3-thione 169
Conformational freedom of metalloproteins revealed by paramagnetism-assisted NMR 169
Insights into Domain-Domain Motions in Proteins and RNA from Solution NMR 169
SSNMR of biosilica-entrapped enzymes permits an easy assessment of preservation of native conformation in atomic detail 169
NMR quality control of fragment libraries for screening 167
Paramagnetic Properties of a Crystalline Iron-Sulfur Protein by Magic-Angle Spinning NMR Spectroscopy 167
Site-Selective Functionalized PD-1 Mutant for a Modular Immunological Activity against Cancer Cells 166
A paramagnetic probe to localize residues next to carboxylates on protein surface 165
Totale 22.391
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Categoria #
all - tutte 93.530
article - articoli 0
book - libri 0
conference - conferenze 0
curatela - curatele 0
other - altro 0
patent - brevetti 0
selected - selezionate 0
volume - volumi 0
Totale 93.530
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Totale Lug Ago Sett Ott Nov Dic Gen Feb Mar Apr Mag Giu
2021/2022986 0 0 0 54 61 56 61 103 87 52 201 311
2022/20233.200 293 620 186 270 219 561 420 140 271 36 79 105
2023/20241.286 70 135 174 77 84 198 52 217 26 119 75 59
2024/20259.029 305 834 639 1.337 2.422 1.462 200 625 309 182 346 368
2025/202610.982 900 2.275 967 1.049 1.073 361 1.084 496 602 584 351 1.240
2026/20271.913 440 289 1.117 67 0 0 0 0 0 0 0 0
Totale 33.898