STEFANI, MASSIMO
 Distribuzione geografica
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Continente #
NA - Nord America 12.852
EU - Europa 10.994
AS - Asia 4.427
SA - Sud America 721
OC - Oceania 130
AF - Africa 128
Continente sconosciuto - Info sul continente non disponibili 9
Totale 29.261
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Nazione #
US - Stati Uniti d'America 12.750
PL - Polonia 4.122
RU - Federazione Russa 2.770
SG - Singapore 1.269
HK - Hong Kong 893
CN - Cina 888
IT - Italia 858
SE - Svezia 852
IE - Irlanda 809
BR - Brasile 606
DE - Germania 462
KR - Corea 447
UA - Ucraina 402
VN - Vietnam 357
FI - Finlandia 264
GB - Regno Unito 174
IN - India 166
AU - Australia 125
FR - Francia 94
TR - Turchia 81
ID - Indonesia 61
ES - Italia 56
JO - Giordania 53
CA - Canada 45
AR - Argentina 44
CI - Costa d'Avorio 38
BD - Bangladesh 37
NL - Olanda 35
JP - Giappone 34
MX - Messico 31
CH - Svizzera 30
IQ - Iraq 29
ZA - Sudafrica 23
SC - Seychelles 21
EC - Ecuador 15
CO - Colombia 14
MA - Marocco 13
BE - Belgio 12
PK - Pakistan 11
TN - Tunisia 11
UZ - Uzbekistan 10
AE - Emirati Arabi Uniti 9
KZ - Kazakistan 9
PY - Paraguay 9
SA - Arabia Saudita 8
VE - Venezuela 8
AZ - Azerbaigian 7
CL - Cile 7
LT - Lituania 7
PE - Perù 7
BG - Bulgaria 6
DO - Repubblica Dominicana 6
EU - Europa 6
GE - Georgia 6
IL - Israele 6
IR - Iran 6
MY - Malesia 6
PT - Portogallo 6
RO - Romania 6
TW - Taiwan 6
BO - Bolivia 5
EG - Egitto 5
KE - Kenya 5
NZ - Nuova Zelanda 5
PH - Filippine 5
UY - Uruguay 5
CZ - Repubblica Ceca 4
DK - Danimarca 4
GT - Guatemala 4
HN - Honduras 4
JM - Giamaica 4
NP - Nepal 4
AT - Austria 3
BH - Bahrain 3
ET - Etiopia 3
GR - Grecia 3
HU - Ungheria 3
KG - Kirghizistan 3
OM - Oman 3
XK - ???statistics.table.value.countryCode.XK??? 3
AL - Albania 2
AO - Angola 2
CR - Costa Rica 2
DZ - Algeria 2
LV - Lettonia 2
MT - Malta 2
MU - Mauritius 2
PA - Panama 2
SY - Repubblica araba siriana 2
TH - Thailandia 2
TT - Trinidad e Tobago 2
AM - Armenia 1
BA - Bosnia-Erzegovina 1
BJ - Benin 1
BN - Brunei Darussalam 1
BS - Bahamas 1
CM - Camerun 1
EE - Estonia 1
GA - Gabon 1
GY - Guiana 1
Totale 29.252
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Città #
Warsaw 4.120
Santa Clara 2.637
Fairfield 1.217
Ashburn 964
Singapore 823
Dublin 808
Chandler 787
Hong Kong 722
Jacksonville 631
Woodbridge 562
Cambridge 515
Houston 472
Seattle 464
Seoul 432
Wilmington 404
Beijing 331
Buffalo 262
Florence 211
Princeton 211
Ann Arbor 187
San Jose 186
Boston 164
Altamura 161
Los Angeles 161
Hefei 160
Dong Ket 145
Dallas 140
Lawrence 137
Boardman 134
The Dalles 131
Melbourne 121
Moscow 107
Mumbai 106
Munich 95
Ho Chi Minh City 77
Medford 76
San Diego 74
Helsinki 57
New York 57
Rome 55
Shanghai 53
Jakarta 51
Bremen 50
São Paulo 50
Izmir 43
Milan 43
Hanoi 42
Kent 39
Abidjan 38
Council Bluffs 38
Norwalk 38
West Jordan 36
Clifton 34
Falls Church 33
Turku 33
Auburn Hills 28
Redondo Beach 28
Barcelona 27
Tokyo 27
Paris 26
Phoenix 26
Hillsboro 21
Bern 19
Frankfurt Am Main 19
Rio de Janeiro 19
Andover 18
London 18
Tianjin 18
Dearborn 17
Toronto 17
Chicago 15
Salerno 15
Belo Horizonte 14
Brasília 14
Denver 14
Pune 14
Yubileyny 14
Curitiba 13
Toulouse 13
Frankfurt am Main 12
Porto Alegre 12
Brussels 11
Chennai 11
Johannesburg 11
Montreal 11
Orem 11
Verona 11
Brooklyn 10
Istanbul 10
Stockholm 10
Baghdad 9
Buenos Aires 9
Guangzhou 9
Redwood City 9
Ribeirão Preto 9
Seongnam 9
Tashkent 9
Campinas 8
Portsmouth 8
Tappahannock 8
Totale 20.386
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Nome #
A causative link between the structure of aberrant protein oligomers and their toxicity 383
The polyphenol oleuropein aglycone protects TgCRND8 mice against Aß plaque pathology 346
Oleuropein aglycone protects against pyroglutamylated-3 amyloid-ß toxicity: biochemical, epigenetic and functional correlates 343
Biochemical and Electrophysiological Modification of Amyloid Transthyretin on Cardiomyocytes 338
Oleuropein Aglycone: A Possible Drug against Degenerative Conditions. In Vivo Evidence of its Effectiveness against Alzheimer's Disease 332
Uso della oleuropeina e suoi derivati nel trattamento del diabete mellito di tipo 2 e di patologie associate a fenomeni di aggregazione di proteine 326
Oleuropein aglycone induces autophagy via the AMPK/mTOR signalling pathway: A mechanistic insight 322
Protein Folding and Aggregation into Amyloid: The Interference by Natural Phenolic Compounds 321
Dephosphorylation of tyrosine phosphorylated synthetic peptides by rat liver phosphotyrosine protein phosphatase isoenzymes 315
proteomic analysis of cells exposed to prefibrillar aggregates of HypF-N 309
Mild exposure of RIN-5F β-cells to human islet amyloid polypeptide aggregates upregulates antioxidant enzymes via NADPH oxidase-RAGE: An hormetic stimulus 307
Binding affinity of amyloid oligomers to cellular membranes is a generic indicator of cellular dysfunction in protein misfolding diseases 297
Seladin-1/dhcr24 protects neuroblastoma cells against aβ toxicity by increasing membrane cholesterol content 296
Properties of N-terminus truncated and C-terminus mutated muscle acylphosphatases. 294
Soluble Oligomers Require a Ganglioside to Trigger Neuronal Calcium Overload 288
Patterns of cell death triggered in two different cell lines by HypF-N prefibrillar aggregates. 285
Molecular insights into cell toxicity of a novel familial amyloidogenic variant of β2-microglobulin 285
Employing AD animal models for translational research: focus on dietary components 277
Interaction of toxic and non-toxic HypF-N oligomers with lipid bilayers investigated at high resolution with atomic force microscopy 269
Single molecule experiments emphasize GM1 as a key player of the different cytotoxicity of structurally distinct Aβ1-42 oligomers 269
Oleuropein aglycone protects against MAO-A-induced autophagy impairment and cardiomyocyte death through activation of TFEB. 263
Toxic HypF-N oligomers selectively bind the plasma membrane to impair cell adhesion capability 253
The polyphenol oleuropein aglycone modulates the PARP1-SIRT1 interplay: an in vitro and in vivo study 239
The complete amino acid sequence of the low molecular weight cytosolic acid phosphatase 233
Oleuropein aglycone protects transgenic C. elegans strains expressing Abeta42 by reducing plauqe load and motor deficit 233
Thermodynamics and kinetics of folding of common type acylphosphatase 231
Looking for residues involved in the muscle acylphosphatase catalytic mechanism and structural stabilization: role of Asn41, Ther42 and Thr46 229
Single particle tracking to study the binding of protein misfolded oligomer to membrane ganglioside GM1 225
Molecular links between aberrant protein oligomers and neurodegeneration in Alzheimer’s disease 224
Nutraceutical properties of olive oli polyphenols. An itinerary from cultured cells through animal models to humans 217
Aspartic-129 is an essential residue in the catalytic mechanism of the low M(r) phosphotyrosine protein phosphatase 215
S-Homocysteinylation effects on transthyretin: worsening of cardiomyopathy onset 215
A specific nanobody prevents amyloidogenesis of D76N β2-microglobulin in vitro and modifies its tissue distribution in vivo 215
1,2,4-trihydroxynaphthalene-2-O-β-D-glucopyranoside delays amyloid-β42 aggregation and reduces amyloid cytotoxicity 211
Crystal structure and anion binding in the prokaryotic hydrogenase maturation factor HypF acylphosphatase-like domain. 207
Affinity chromatographic purification of horse muscle acylphosphatase: evidence of the existence of multiple molecular forms. 203
Arg23 is involved in the catalytic site of muscle acylphosphatase. 202
Amyloid aggregation: role of biological membranes and the aggregate-membrane system 199
Olive oil polyphenols can be useful to prevent aging-associated neurodegeneration 199
1,2,4-trihydroxynapthalene-2-O-b-D-glucopyranoside: A new powerful antioxidant and inhibitor of Ab42 aggregation isolated from the leaves of Lawsonia inermis 194
A FTIR microspectroscopy study of the structural and biochemical perturbations induced by natively folded and aggregated transthyretin in HL-1 cardiomyocytes 191
Assessing the role of aromatic residues in the amyloid aggregation of human muscle acylphosphatase 187
Differentiation increases the resistance of neuronal cells to amyloid toxicity 185
Acylphosphatase from human skeletal muscle: purification, some properties and levels in normal and myopathic muscles 182
null 181
The (1-63) region of the p53 transactivation domain aggregates in vitro into cytotoxic amyloid assemblies 180
Acylphosphatase increases the rate of ethanol production from glucose in cell-free extract of Saccharomyces cerevisiae 179
Antisense peptides to 43-57 region of acylphosphatase and to 46-60 region of two isoenzymes of a low Mr PTPase do not interact with the corresponding proteins. 178
A protective role for lipid raft cholesterol againsy amyloid-induced membrane damage in human neuroblastoma cells 177
Neuronal differentiation of human mesenchymal stromal cells increases their resistance to Aβ42 aggregate toxicity. 169
The polyphenol Oleuropein aglycone hinders the growth of toxic transthyretin amyloid assemblies 168
Expression, purification and preliminary crystal analysis of the human low Mr phosphotyrosine protein phosphatase isoform 1. 165
Insights into the molecular basis of the differing susceptibility of varying cell types to the toxicity of amyloid aggregates 164
Oleuropein aglycone and polyphenols from olive mill waste water ameliorate cognitive deficits and neuropathology 164
CA2+-ATPASE FROM SARCOPLASMIC RETICULUM: ACYLPHOSPHATASE ACTIVITY 163
SASP-LIKE PHENOTYPE IN ALZHEIMER CELLULAR MODELS: MODULATION BY NATURAL PHENOLIC COMPOUNDS 163
Biological function in a non-native partially folded state of a protein. 160
C-terminal region contributes to muscle acylphosphatase three-dimensional structure stabilisation 160
Membrane lipid composition and its physicochemical properties define cell vulnerability to aberrant protein oligomers 160
Healthy Effects of Plant Polyphenols: Molecular Mechanisms 158
Oleuropein aglycone counteracts Aβ42 toxicity in the rat brain 157
Aggregation of the acylphosphatase from S. solfataricus. The folded and partially unfolded states can be both precursors for amyloid formation. 155
null 154
Olive polyphenols: new promising agents to combat aging-associated neurodegeneration 154
Oleuropein aglycon relieves memory impairments, induces brain autophagy and reduces Aß load in the TgCRND8 mouse model of Alzheimer’s Disease 153
Nonspecific interaction of prefibrillar amyloid aggregates with glutamatergic receptors results in Ca2+ increase in primary neuronal cells 149
Effect of acylphosphates on Ca2+ uptake by sarcoplasmic reticulum vesicles. 149
Nutraceutical properties of olive oil polyphenols. An itinerary from cultured cells through animal models to humans 148
Expression and turnover of acylphosphatase (muscular isoenzyme) in L6 myoblasts during myogenesis. 147
Comparison of the folding processes of distantly related proteins. Importance of hydrophobic content in folding. 146
Oleuropein aglycone and hydroxytyrosol interfere differently with toxic Aβ 1-42 aggregation 144
Replicating neuroblastoma cells in different cell cycle phases display different vulnerability to amyloid toxicity 143
Different ataxin-3 amyloid aggregates induce intracellular Ca2+ deregulation by different mechanisms in cerebellar granule cells 143
Preparation and some properties of a dimeric form (S-S) of horse muscle acylphosphatase 142
Oleuropein aglycon prevents cytotoxic amyloid aggregation of human amylin 142
Purification and characterization of rabbit muscle acylphosphatase in the thiol (-SH) form. 140
Amyloid polymorphisms: structural basis and significance in biology and molecular medicine 140
Differing molecular mechanisms appear to underlie early toxicity of pre-fibrillar HypF-N aggregates to different cell types 139
CRYSTALLISATION OF A LOW MOLECULAR WEIGHT PHOSPHOTYROSINE PROTEIN PHOSPHATASE FROM BOVINE LIVER. 139
The yeast prion Ure2p native-like assemblies are toxic to mammalian cells regardless to their aggregation state 138
Monitoring the process of HypF fibrillization and liposome permeabilization by protofibrils. 137
Abeta(1-42) aggregates into non-toxic amyloid assemblies in the presence of the natural polyphenol oleuropein aglycon 137
Rabbit skeletal muscle acylphosphatase: the amino acid sequence of form Ra1. 136
Guinea pig acylphosphatase: the amino acid sequence 136
Il nuovo medicina e biologia 136
Autophagy Dysregulation in Alzheimer’s Disease: Plant Polyphenols as A Possible Preventive and Therapeutic Treatment. 136
Investigation of the effects of copper ions on protein aggregation using a model system. 136
The amyloid-cell membrane system. The interplay between the biophysical features of oligomers/fibrils and cell membrane defines amyloid toxicity 135
Kinetic partitioning of protein folding and aggregation 133
Horse brain acylphosphatase: purification and characterization 133
Inherent toxicity of aggregates implies a common mechanism for protein misfolding diseases 132
Beneficial properties of natural phenols. Highlight on protection against pathological conditions associated with amyloid aggregation 132
LYSOZYME INTERACTION WITH NEGATIVELY CHARGED LIPID BILAYERS: PROTEIN AGGREGATION AND MEMBRANE FUSION 131
Oleuropein aglycone induces autophagy in neonatal rat cardiomyocytes. Evidences of beneficial effects in an “in vitro” model of cardiomyopathy characterized by autophagy. 131
Reduction of the amyloidogenicity of a protein by specific binding of ligands to the native conformation. 130
Prefibrillar amyloid aggregates could be generic toxins in higher organisms 130
Interactions of lysozyme with phospholipid vesicles: effects of vesicle biophysical features on protein misfolding and aggregation 129
Autophagy-related proteins: potential diagnostic and prognostic biomarkers of aging-related diseases. 128
The primary structure of turkey muscle acylphosphatase. 128
Natively folded HypF-N and its early amyloid aggregates interact with phospholipid monolayers and destabilize supported phospholipid bilayers 127
Totale 19.618
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Categoria #
all - tutte 73.655
article - articoli 0
book - libri 0
conference - conferenze 0
curatela - curatele 0
other - altro 0
patent - brevetti 0
selected - selezionate 0
volume - volumi 0
Totale 73.655
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Totale Lug Ago Sett Ott Nov Dic Gen Feb Mar Apr Mag Giu
2020/20211.369 0 0 0 0 0 0 99 247 188 398 125 312
2021/20221.363 56 132 79 58 73 55 61 88 75 59 304 323
2022/20233.372 346 445 162 338 269 639 478 169 354 11 115 46
2023/20241.163 48 145 204 67 74 173 32 241 20 64 41 54
2024/20257.548 267 834 446 1.137 2.408 882 130 444 354 183 256 207
2025/20265.019 898 1.202 682 615 871 402 349 0 0 0 0 0
Totale 29.452