STEFANI, MASSIMO
 Distribuzione geografica
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Continente #
NA - Nord America 13.971
EU - Europa 12.347
AS - Asia 5.450
SA - Sud America 743
AF - Africa 168
OC - Oceania 132
Continente sconosciuto - Info sul continente non disponibili 9
Totale 32.820
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Nazione #
US - Stati Uniti d'America 13.840
PL - Polonia 4.123
RU - Federazione Russa 2.757
IT - Italia 1.957
SG - Singapore 1.506
CN - Cina 1.143
HK - Hong Kong 921
SE - Svezia 858
IE - Irlanda 806
VN - Vietnam 735
BR - Brasile 618
DE - Germania 468
KR - Corea 453
UA - Ucraina 403
FI - Finlandia 284
FR - Francia 273
GB - Regno Unito 194
IN - India 189
AU - Australia 126
TR - Turchia 78
ID - Indonesia 66
CA - Canada 61
ES - Italia 60
BD - Bangladesh 56
JO - Giordania 53
JP - Giappone 48
NL - Olanda 48
AR - Argentina 45
CI - Costa d'Avorio 39
IQ - Iraq 38
MX - Messico 35
CH - Svizzera 34
ZA - Sudafrica 28
PK - Pakistan 20
SC - Seychelles 20
NG - Nigeria 19
AE - Emirati Arabi Uniti 18
EC - Ecuador 18
MA - Marocco 15
TN - Tunisia 14
BE - Belgio 13
CO - Colombia 13
UZ - Uzbekistan 13
IL - Israele 11
MY - Malesia 11
PT - Portogallo 11
VE - Venezuela 11
CL - Cile 10
EG - Egitto 10
KZ - Kazakistan 10
NP - Nepal 9
PH - Filippine 9
PY - Paraguay 9
SA - Arabia Saudita 9
LT - Lituania 8
RO - Romania 8
AZ - Azerbaigian 7
DO - Repubblica Dominicana 7
JM - Giamaica 7
PE - Perù 7
TH - Thailandia 7
BG - Bulgaria 6
EU - Europa 6
GE - Georgia 6
KE - Kenya 6
NZ - Nuova Zelanda 6
TW - Taiwan 6
BO - Bolivia 5
DK - Danimarca 5
IR - Iran 5
UY - Uruguay 5
BH - Bahrain 4
CR - Costa Rica 4
CZ - Repubblica Ceca 4
ET - Etiopia 4
GR - Grecia 4
GT - Guatemala 4
HN - Honduras 4
OM - Oman 4
SY - Repubblica araba siriana 4
AO - Angola 3
AT - Austria 3
DZ - Algeria 3
HU - Ungheria 3
KG - Kirghizistan 3
MU - Mauritius 3
PA - Panama 3
XK - ???statistics.table.value.countryCode.XK??? 3
AL - Albania 2
GA - Gabon 2
LK - Sri Lanka 2
LV - Lettonia 2
MD - Moldavia 2
MT - Malta 2
RS - Serbia 2
TT - Trinidad e Tobago 2
AM - Armenia 1
BA - Bosnia-Erzegovina 1
BJ - Benin 1
BN - Brunei Darussalam 1
Totale 32.803
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Città #
Warsaw 4.120
Santa Clara 2.630
Ashburn 1.404
Fairfield 1.217
Singapore 1.043
Dublin 804
Chandler 784
Hong Kong 735
Jacksonville 633
Woodbridge 562
Cambridge 515
Houston 474
Seattle 467
Seoul 430
Wilmington 411
Milan 400
Beijing 341
San Jose 309
Buffalo 262
Florence 225
The Dalles 225
Princeton 211
Ho Chi Minh City 192
Ann Arbor 187
Rome 179
Los Angeles 175
Lauterbourg 169
Boston 164
Hefei 162
Altamura 161
Dallas 148
Dong Ket 145
Lawrence 138
Boardman 137
Council Bluffs 136
Hanoi 132
Melbourne 120
Mumbai 109
Moscow 108
Munich 93
Helsinki 77
San Diego 77
Medford 74
New York 69
Shanghai 58
Naples 55
Jakarta 53
São Paulo 51
Bremen 50
Turin 45
Izmir 44
Tokyo 40
Abidjan 39
Kent 39
Norwalk 39
Orem 37
West Jordan 36
Clifton 33
Falls Church 33
Phoenix 33
Turku 33
Bologna 32
Auburn Hills 28
Barcelona 28
Redondo Beach 28
Paris 25
Da Nang 24
Haiphong 24
Hillsboro 21
Verona 21
London 20
Bern 19
Frankfurt Am Main 19
Genoa 19
Rio de Janeiro 19
San Francisco 19
Abuja 18
Andover 18
Palermo 18
Tianjin 18
Toronto 18
Dearborn 17
Denver 17
Figino 17
Frankfurt am Main 17
Guangzhou 17
Pune 17
Salerno 17
Amsterdam 16
Brasília 16
Chennai 16
Chicago 16
Baghdad 15
Brooklyn 15
Bari 14
Belo Horizonte 14
Hải Dương 14
Yubileyny 14
Curitiba 13
Johannesburg 13
Totale 22.603
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Nome #
A causative link between the structure of aberrant protein oligomers and their toxicity 476
Oleuropein aglycone protects against pyroglutamylated-3 amyloid-ß toxicity: biochemical, epigenetic and functional correlates 400
Oleuropein aglycone induces autophagy via the AMPK/mTOR signalling pathway: A mechanistic insight 394
The polyphenol oleuropein aglycone protects TgCRND8 mice against Aß plaque pathology 369
Oleuropein Aglycone: A Possible Drug against Degenerative Conditions. In Vivo Evidence of its Effectiveness against Alzheimer's Disease 366
Biochemical and Electrophysiological Modification of Amyloid Transthyretin on Cardiomyocytes 360
Protein Folding and Aggregation into Amyloid: The Interference by Natural Phenolic Compounds 352
Uso della oleuropeina e suoi derivati nel trattamento del diabete mellito di tipo 2 e di patologie associate a fenomeni di aggregazione di proteine 347
Dephosphorylation of tyrosine phosphorylated synthetic peptides by rat liver phosphotyrosine protein phosphatase isoenzymes 343
Seladin-1/dhcr24 protects neuroblastoma cells against aβ toxicity by increasing membrane cholesterol content 336
Mild exposure of RIN-5F β-cells to human islet amyloid polypeptide aggregates upregulates antioxidant enzymes via NADPH oxidase-RAGE: An hormetic stimulus 330
proteomic analysis of cells exposed to prefibrillar aggregates of HypF-N 326
Binding affinity of amyloid oligomers to cellular membranes is a generic indicator of cellular dysfunction in protein misfolding diseases 326
Properties of N-terminus truncated and C-terminus mutated muscle acylphosphatases. 325
Molecular insights into cell toxicity of a novel familial amyloidogenic variant of β2-microglobulin 311
Soluble Oligomers Require a Ganglioside to Trigger Neuronal Calcium Overload 311
Employing AD animal models for translational research: focus on dietary components 308
Oleuropein aglycone protects against MAO-A-induced autophagy impairment and cardiomyocyte death through activation of TFEB. 307
Single molecule experiments emphasize GM1 as a key player of the different cytotoxicity of structurally distinct Aβ1-42 oligomers 299
Patterns of cell death triggered in two different cell lines by HypF-N prefibrillar aggregates. 298
Interaction of toxic and non-toxic HypF-N oligomers with lipid bilayers investigated at high resolution with atomic force microscopy 296
Toxic HypF-N oligomers selectively bind the plasma membrane to impair cell adhesion capability 281
The polyphenol oleuropein aglycone modulates the PARP1-SIRT1 interplay: an in vitro and in vivo study 263
Looking for residues involved in the muscle acylphosphatase catalytic mechanism and structural stabilization: role of Asn41, Ther42 and Thr46 256
Thermodynamics and kinetics of folding of common type acylphosphatase 256
Molecular links between aberrant protein oligomers and neurodegeneration in Alzheimer’s disease 255
The complete amino acid sequence of the low molecular weight cytosolic acid phosphatase 251
Oleuropein aglycone protects transgenic C. elegans strains expressing Abeta42 by reducing plauqe load and motor deficit 248
Single particle tracking to study the binding of protein misfolded oligomer to membrane ganglioside GM1 248
S-Homocysteinylation effects on transthyretin: worsening of cardiomyopathy onset 241
Nutraceutical properties of olive oli polyphenols. An itinerary from cultured cells through animal models to humans 239
Aspartic-129 is an essential residue in the catalytic mechanism of the low M(r) phosphotyrosine protein phosphatase 236
Olive oil polyphenols can be useful to prevent aging-associated neurodegeneration 231
A specific nanobody prevents amyloidogenesis of D76N β2-microglobulin in vitro and modifies its tissue distribution in vivo 228
Affinity chromatographic purification of horse muscle acylphosphatase: evidence of the existence of multiple molecular forms. 227
Crystal structure and anion binding in the prokaryotic hydrogenase maturation factor HypF acylphosphatase-like domain. 224
1,2,4-trihydroxynaphthalene-2-O-β-D-glucopyranoside delays amyloid-β42 aggregation and reduces amyloid cytotoxicity 224
Acylphosphatase increases the rate of ethanol production from glucose in cell-free extract of Saccharomyces cerevisiae 217
Amyloid aggregation: role of biological membranes and the aggregate-membrane system 217
Arg23 is involved in the catalytic site of muscle acylphosphatase. 214
1,2,4-trihydroxynapthalene-2-O-b-D-glucopyranoside: A new powerful antioxidant and inhibitor of Ab42 aggregation isolated from the leaves of Lawsonia inermis 210
Assessing the role of aromatic residues in the amyloid aggregation of human muscle acylphosphatase 209
A FTIR microspectroscopy study of the structural and biochemical perturbations induced by natively folded and aggregated transthyretin in HL-1 cardiomyocytes 205
Biological function in a non-native partially folded state of a protein. 202
Acylphosphatase from human skeletal muscle: purification, some properties and levels in normal and myopathic muscles 202
Differentiation increases the resistance of neuronal cells to amyloid toxicity 201
A protective role for lipid raft cholesterol againsy amyloid-induced membrane damage in human neuroblastoma cells 201
The (1-63) region of the p53 transactivation domain aggregates in vitro into cytotoxic amyloid assemblies 197
Healthy Effects of Plant Polyphenols: Molecular Mechanisms 194
Antisense peptides to 43-57 region of acylphosphatase and to 46-60 region of two isoenzymes of a low Mr PTPase do not interact with the corresponding proteins. 190
Neuronal differentiation of human mesenchymal stromal cells increases their resistance to Aβ42 aggregate toxicity. 190
Expression, purification and preliminary crystal analysis of the human low Mr phosphotyrosine protein phosphatase isoform 1. 188
Oleuropein aglycone counteracts Aβ42 toxicity in the rat brain 187
Oleuropein aglycone and polyphenols from olive mill waste water ameliorate cognitive deficits and neuropathology 185
The polyphenol Oleuropein aglycone hinders the growth of toxic transthyretin amyloid assemblies 183
null 181
CA2+-ATPASE FROM SARCOPLASMIC RETICULUM: ACYLPHOSPHATASE ACTIVITY 180
Insights into the molecular basis of the differing susceptibility of varying cell types to the toxicity of amyloid aggregates 179
Oleuropein aglycon relieves memory impairments, induces brain autophagy and reduces Aß load in the TgCRND8 mouse model of Alzheimer’s Disease 174
C-terminal region contributes to muscle acylphosphatase three-dimensional structure stabilisation 173
Membrane lipid composition and its physicochemical properties define cell vulnerability to aberrant protein oligomers 173
Aggregation of the acylphosphatase from S. solfataricus. The folded and partially unfolded states can be both precursors for amyloid formation. 172
Effect of acylphosphates on Ca2+ uptake by sarcoplasmic reticulum vesicles. 170
Expression and turnover of acylphosphatase (muscular isoenzyme) in L6 myoblasts during myogenesis. 169
Nutraceutical properties of olive oil polyphenols. An itinerary from cultured cells through animal models to humans 167
Oleuropein aglycon prevents cytotoxic amyloid aggregation of human amylin 166
The amyloid-cell membrane system. The interplay between the biophysical features of oligomers/fibrils and cell membrane defines amyloid toxicity 165
Comparison of the folding processes of distantly related proteins. Importance of hydrophobic content in folding. 163
Olive polyphenols: new promising agents to combat aging-associated neurodegeneration 163
Differing molecular mechanisms appear to underlie early toxicity of pre-fibrillar HypF-N aggregates to different cell types 161
Autophagy-related proteins: potential diagnostic and prognostic biomarkers of aging-related diseases. 160
Guinea pig acylphosphatase: the amino acid sequence 160
Purification and characterization of rabbit muscle acylphosphatase in the thiol (-SH) form. 160
Different ataxin-3 amyloid aggregates induce intracellular Ca2+ deregulation by different mechanisms in cerebellar granule cells 159
Nonspecific interaction of prefibrillar amyloid aggregates with glutamatergic receptors results in Ca2+ increase in primary neuronal cells 157
Monitoring the process of HypF fibrillization and liposome permeabilization by protofibrils. 157
Oleuropein aglycone and hydroxytyrosol interfere differently with toxic Aβ 1-42 aggregation 156
Abeta(1-42) aggregates into non-toxic amyloid assemblies in the presence of the natural polyphenol oleuropein aglycon 155
Beta2-microglobulin is potentially neurotoxic, but the blood brain barrier is likely to protect the brain from its toxicity 155
LYSOZYME INTERACTION WITH NEGATIVELY CHARGED LIPID BILAYERS: PROTEIN AGGREGATION AND MEMBRANE FUSION 154
null 154
Rabbit skeletal muscle acylphosphatase: the amino acid sequence of form Ra1. 153
Autophagy Dysregulation in Alzheimer’s Disease: Plant Polyphenols as A Possible Preventive and Therapeutic Treatment. 153
Investigation of the effects of copper ions on protein aggregation using a model system. 153
CRYSTALLISATION OF A LOW MOLECULAR WEIGHT PHOSPHOTYROSINE PROTEIN PHOSPHATASE FROM BOVINE LIVER. 153
Replicating neuroblastoma cells in different cell cycle phases display different vulnerability to amyloid toxicity 152
Protein misfolding and aggregation: new examples in medicine and biology of the dark side of the protein world 152
Amyloid polymorphisms: structural basis and significance in biology and molecular medicine 152
Oleuropein aglycone stabilizes the monomeric α-synuclein and favours the growth of non-toxic aggregates 151
Oleuropein aglycone induces autophagy in neonatal rat cardiomyocytes. Evidences of beneficial effects in an “in vitro” model of cardiomyopathy characterized by autophagy. 151
Preparation and some properties of a dimeric form (S-S) of horse muscle acylphosphatase 150
Inherent toxicity of aggregates implies a common mechanism for protein misfolding diseases 149
The yeast prion Ure2p native-like assemblies are toxic to mammalian cells regardless to their aggregation state 148
Beneficial properties of natural phenols. Highlight on protection against pathological conditions associated with amyloid aggregation 148
Il nuovo medicina e biologia 147
Horse brain acylphosphatase: purification and characterization 146
Interactions of lysozyme with phospholipid vesicles: effects of vesicle biophysical features on protein misfolding and aggregation 146
Oleuropein aglycone induces autophagy in neuroblastoma cells: a mechanicistic insight. 145
Prefibrillar amyloid aggregates could be generic toxins in higher organisms 145
The Amphipathic GM1 Molecule Stabilizes Amyloid Aggregates, Preventing their Cytotoxicity 145
Totale 21.802
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Categoria #
all - tutte 82.612
article - articoli 0
book - libri 0
conference - conferenze 0
curatela - curatele 0
other - altro 0
patent - brevetti 0
selected - selezionate 0
volume - volumi 0
Totale 82.612
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Totale Lug Ago Sett Ott Nov Dic Gen Feb Mar Apr Mag Giu
2020/2021312 0 0 0 0 0 0 0 0 0 0 0 312
2021/20221.359 56 131 79 58 73 55 61 87 75 59 304 321
2022/20233.355 345 444 159 338 268 637 474 169 353 11 113 44
2023/20241.147 47 145 203 67 72 172 32 241 20 64 39 45
2024/20257.482 260 830 442 1.129 2.389 873 130 443 349 181 252 204
2025/20268.686 894 1.181 677 609 865 399 1.100 434 577 481 197 1.272
Totale 33.008