STEFANI, MASSIMO
 Distribuzione geografica
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Continente #
NA - Nord America 11.125
EU - Europa 9.834
AS - Asia 1.413
AF - Africa 66
SA - Sud America 28
Continente sconosciuto - Info sul continente non disponibili 6
OC - Oceania 6
Totale 22.478
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Nazione #
US - Stati Uniti d'America 11.102
PL - Polonia 4.102
RU - Federazione Russa 2.025
SE - Svezia 840
IT - Italia 811
IE - Irlanda 803
SG - Singapore 396
UA - Ucraina 395
HK - Hong Kong 377
DE - Germania 354
CN - Cina 212
FI - Finlandia 193
VN - Vietnam 161
IN - India 132
GB - Regno Unito 125
FR - Francia 63
TR - Turchia 61
JO - Giordania 48
ES - Italia 43
CI - Costa d'Avorio 37
CH - Svizzera 22
SC - Seychelles 21
BR - Brasile 20
CA - Canada 20
NL - Olanda 17
BE - Belgio 12
KR - Corea 12
BG - Bulgaria 6
EU - Europa 6
PT - Portogallo 6
AU - Australia 5
LT - Lituania 5
AR - Argentina 4
JP - Giappone 4
GR - Grecia 3
RO - Romania 3
BO - Bolivia 2
DK - Danimarca 2
EG - Egitto 2
IR - Iran 2
MU - Mauritius 2
TN - Tunisia 2
TW - Taiwan 2
AE - Emirati Arabi Uniti 1
AT - Austria 1
BS - Bahamas 1
CL - Cile 1
CM - Camerun 1
CO - Colombia 1
CZ - Repubblica Ceca 1
GT - Guatemala 1
HU - Ungheria 1
IM - Isola di Man 1
IQ - Iraq 1
MX - Messico 1
MY - Malesia 1
NZ - Nuova Zelanda 1
PH - Filippine 1
SA - Arabia Saudita 1
TH - Thailandia 1
ZA - Sudafrica 1
Totale 22.478
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Città #
Warsaw 4.102
Santa Clara 2.618
Fairfield 1.217
Dublin 803
Chandler 787
Jacksonville 630
Woodbridge 562
Ashburn 558
Cambridge 513
Houston 464
Seattle 460
Wilmington 403
Singapore 307
Princeton 211
Hong Kong 208
Florence 203
Ann Arbor 187
Altamura 161
Boston 153
Dong Ket 145
Lawrence 137
Buffalo 135
Boardman 134
Mumbai 104
Beijing 94
Medford 76
San Diego 74
Moscow 67
Bremen 50
Rome 50
Shanghai 46
Izmir 43
Milan 38
Norwalk 38
Abidjan 37
West Jordan 36
Falls Church 33
Los Angeles 32
New York 30
Auburn Hills 28
Barcelona 25
Helsinki 25
Kent 22
Hillsboro 21
Phoenix 20
Bern 19
Frankfurt Am Main 19
Andover 18
Dearborn 17
Salerno 15
Yubileyny 14
Toulouse 13
Pune 12
Toronto 12
Brussels 11
Verona 11
London 10
Redwood City 9
Seongnam 9
Tappahannock 8
Santa Maria A Monte 7
Cascina 6
Guangzhou 6
Laurel 6
Munich 6
Sofia 6
Tianjin 6
Usingen 6
Berlin 5
Cagliari 5
Chicago 5
Fiesole 5
Nagold 5
Naples 5
Ottawa 5
Porto Alegre 5
Zola Predosa 5
Buenos Aires 4
Chieti 4
Falkenstein 4
Naaldwijk 4
Paris 4
San Lazzaro Di Savena 4
Scandicci 4
Bursa 3
Castelliri 3
Cecina 3
Evora 3
Madrid 3
Napoli 3
Orenburg 3
Parma 3
Philadelphia 3
Pisa 3
Porto 3
Redmond 3
Romola 3
Saint Petersburg 3
Shenzhen 3
Valencia 3
Totale 16.454
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Nome #
Uso della oleuropeina e suoi derivati nel trattamento del diabete mellito di tipo 2 e di patologie associate a fenomeni di aggregazione di proteine 294
Oleuropein aglycone induces autophagy via the AMPK/mTOR signalling pathway: A mechanistic insight 284
Oleuropein Aglycone: A Possible Drug against Degenerative Conditions. In Vivo Evidence of its Effectiveness against Alzheimer's Disease 283
A causative link between the structure of aberrant protein oligomers and their toxicity 282
Dephosphorylation of tyrosine phosphorylated synthetic peptides by rat liver phosphotyrosine protein phosphatase isoenzymes 280
Biochemical and Electrophysiological Modification of Amyloid Transthyretin on Cardiomyocytes 275
The polyphenol oleuropein aglycone protects TgCRND8 mice against Aß plaque pathology 274
Mild exposure of RIN-5F β-cells to human islet amyloid polypeptide aggregates upregulates antioxidant enzymes via NADPH oxidase-RAGE: An hormetic stimulus 270
proteomic analysis of cells exposed to prefibrillar aggregates of HypF-N 267
Oleuropein aglycone protects against pyroglutamylated-3 amyloid-ß toxicity: biochemical, epigenetic and functional correlates 267
Seladin-1/dhcr24 protects neuroblastoma cells against aβ toxicity by increasing membrane cholesterol content 266
Properties of N-terminus truncated and C-terminus mutated muscle acylphosphatases. 265
Protein Folding and Aggregation into Amyloid: The Interference by Natural Phenolic Compounds 257
Patterns of cell death triggered in two different cell lines by HypF-N prefibrillar aggregates. 256
Binding affinity of amyloid oligomers to cellular membranes is a generic indicator of cellular dysfunction in protein misfolding diseases 252
Molecular insights into cell toxicity of a novel familial amyloidogenic variant of β2-microglobulin 247
Soluble Oligomers Require a Ganglioside to Trigger Neuronal Calcium Overload 247
Interaction of toxic and non-toxic HypF-N oligomers with lipid bilayers investigated at high resolution with atomic force microscopy 240
Employing AD animal models for translational research: focus on dietary components 234
Oleuropein aglycone protects against MAO-A-induced autophagy impairment and cardiomyocyte death through activation of TFEB. 230
Single molecule experiments emphasize GM1 as a key player of the different cytotoxicity of structurally distinct Aβ1-42 oligomers 228
Toxic HypF-N oligomers selectively bind the plasma membrane to impair cell adhesion capability 227
Oleuropein aglycone protects transgenic C. elegans strains expressing Abeta42 by reducing plauqe load and motor deficit 209
Thermodynamics and kinetics of folding of common type acylphosphatase 208
The complete amino acid sequence of the low molecular weight cytosolic acid phosphatase 200
Looking for residues involved in the muscle acylphosphatase catalytic mechanism and structural stabilization: role of Asn41, Ther42 and Thr46 197
Single particle tracking to study the binding of protein misfolded oligomer to membrane ganglioside GM1 192
Nutraceutical properties of olive oli polyphenols. An itinerary from cultured cells through animal models to humans 189
Molecular links between aberrant protein oligomers and neurodegeneration in Alzheimer’s disease 188
The polyphenol oleuropein aglycone modulates the PARP1-SIRT1 interplay: an in vitro and in vivo study 186
null 181
A specific nanobody prevents amyloidogenesis of D76N β2-microglobulin in vitro and modifies its tissue distribution in vivo 161
The (1-63) region of the p53 transactivation domain aggregates in vitro into cytotoxic amyloid assemblies 157
null 154
Crystal structure and anion binding in the prokaryotic hydrogenase maturation factor HypF acylphosphatase-like domain. 153
1,2,4-trihydroxynaphthalene-2-O-β-D-glucopyranoside delays amyloid-β42 aggregation and reduces amyloid cytotoxicity 151
The polyphenol Oleuropein aglycone hinders the growth of toxic transthyretin amyloid assemblies 149
1,2,4-trihydroxynapthalene-2-O-b-D-glucopyranoside: A new powerful antioxidant and inhibitor of Ab42 aggregation isolated from the leaves of Lawsonia inermis 146
Aspartic-129 is an essential residue in the catalytic mechanism of the low M(r) phosphotyrosine protein phosphatase 144
Differentiation increases the resistance of neuronal cells to amyloid toxicity 142
A FTIR microspectroscopy study of the structural and biochemical perturbations induced by natively folded and aggregated transthyretin in HL-1 cardiomyocytes 139
Olive oil polyphenols can be useful to prevent aging-associated neurodegeneration 138
S-Homocysteinylation effects on transthyretin: worsening of cardiomyopathy onset 138
Acylphosphatase from human skeletal muscle: purification, some properties and levels in normal and myopathic muscles 133
Amyloid aggregation: role of biological membranes and the aggregate-membrane system 132
Affinity chromatographic purification of horse muscle acylphosphatase: evidence of the existence of multiple molecular forms. 130
Assessing the role of aromatic residues in the amyloid aggregation of human muscle acylphosphatase 128
CA2+-ATPASE FROM SARCOPLASMIC RETICULUM: ACYLPHOSPHATASE ACTIVITY 126
Expression, purification and preliminary crystal analysis of the human low Mr phosphotyrosine protein phosphatase isoform 1. 125
Neuronal differentiation of human mesenchymal stromal cells increases their resistance to Aβ42 aggregate toxicity. 125
Oleuropein aglycone and polyphenols from olive mill waste water ameliorate cognitive deficits and neuropathology 125
Olive polyphenols: new promising agents to combat aging-associated neurodegeneration 125
Healthy Effects of Plant Polyphenols: Molecular Mechanisms 124
Effect of acylphosphates on Ca2+ uptake by sarcoplasmic reticulum vesicles. 123
A protective role for lipid raft cholesterol againsy amyloid-induced membrane damage in human neuroblastoma cells 123
Membrane lipid composition and its physicochemical properties define cell vulnerability to aberrant protein oligomers 123
Biological function in a non-native partially folded state of a protein. 122
Replicating neuroblastoma cells in different cell cycle phases display different vulnerability to amyloid toxicity 121
Nutraceutical properties of olive oil polyphenols. An itinerary from cultured cells through animal models to humans 121
Arg23 is involved in the catalytic site of muscle acylphosphatase. 119
The yeast prion Ure2p native-like assemblies are toxic to mammalian cells regardless to their aggregation state 119
Monitoring the process of HypF fibrillization and liposome permeabilization by protofibrils. 118
Oleuropein aglycone counteracts Aβ42 toxicity in the rat brain 118
Nonspecific interaction of prefibrillar amyloid aggregates with glutamatergic receptors results in Ca2+ increase in primary neuronal cells 117
C-terminal region contributes to muscle acylphosphatase three-dimensional structure stabilisation 117
Preparation and some properties of a dimeric form (S-S) of horse muscle acylphosphatase 115
Oleuropein aglycone and hydroxytyrosol interfere differently with toxic Aβ 1-42 aggregation 115
CRYSTALLISATION OF A LOW MOLECULAR WEIGHT PHOSPHOTYROSINE PROTEIN PHOSPHATASE FROM BOVINE LIVER. 115
Oleuropein aglycon prevents cytotoxic amyloid aggregation of human amylin 114
Antisense peptides to 43-57 region of acylphosphatase and to 46-60 region of two isoenzymes of a low Mr PTPase do not interact with the corresponding proteins. 112
The amyloid-cell membrane system. The interplay between the biophysical features of oligomers/fibrils and cell membrane defines amyloid toxicity 112
Rabbit skeletal muscle acylphosphatase: the amino acid sequence of form Ra1. 111
Investigation of the effects of copper ions on protein aggregation using a model system. 110
Reduction of the amyloidogenicity of a protein by specific binding of ligands to the native conformation. 109
Prefibrillar amyloid aggregates could be generic toxins in higher organisms 109
Rationalization of the effects of mutations on peptide and protein aggregation rates 108
Equilibrium unfolding studies of horse muscle acylphosphatase. 108
Acylphosphatase increases the rate of ethanol production from glucose in cell-free extract of Saccharomyces cerevisiae 107
Purification and characterization of rabbit muscle acylphosphatase in the thiol (-SH) form. 107
Differing molecular mechanisms appear to underlie early toxicity of pre-fibrillar HypF-N aggregates to different cell types 107
Horse brain acylphosphatase: purification and characterization 106
Comparison of the folding processes of distantly related proteins. Importance of hydrophobic content in folding. 105
Natively folded HypF-N and its early amyloid aggregates interact with phospholipid monolayers and destabilize supported phospholipid bilayers 105
Insights into the molecular basis of the differing susceptibility of varying cell types to the toxicity of amyloid aggregates 105
Interactions of lysozyme with phospholipid vesicles: effects of vesicle biophysical features on protein misfolding and aggregation 105
Inherent toxicity of aggregates implies a common mechanism for protein misfolding diseases 104
Different ataxin-3 amyloid aggregates induce intracellular Ca2+ deregulation by different mechanisms in cerebellar granule cells 104
The primary structure of turkey muscle acylphosphatase. 103
Aggregation of the acylphosphatase from S. solfataricus. The folded and partially unfolded states can be both precursors for amyloid formation. 103
Sequence-specific recognition of peptide substrates by the low Mr phosphotyrosine protein phosphatase isoforms 102
Beneficial properties of natural phenols. Highlight on protection against pathological conditions associated with amyloid aggregation 102
Guinea pig acylphosphatase: the amino acid sequence 100
Oleuropein aglycone stabilizes the monomeric α-synuclein and favours the growth of non-toxic aggregates 100
Prefibrillar amyloid protein aggregates share common features of cytotoxicity 100
Three-dimensional structural characterization of a novel Drosophila melanogaster acylphosphatase. 100
Expression and turnover of acylphosphatase (muscular isoenzyme) in L6 myoblasts during myogenesis. 100
Hydrolysis by horse muscle acylphosphatase of (Ca2+ + Mg2+)-ATPase phosphorylated intermediate. 99
Investigating the effects of mutations on protein aggregation in the cell. 99
Generic cell dysfunction in neurodegenerative disorders: role of surfaces in early protein misfolding, aggregation and aggregate cytotoxicity. 97
Kinetic partitioning of protein folding and aggregation 97
Totale 15.656
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Categoria #
all - tutte 54.048
article - articoli 0
book - libri 0
conference - conferenze 0
curatela - curatele 0
other - altro 0
patent - brevetti 0
selected - selezionate 0
volume - volumi 0
Totale 54.048
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Totale Lug Ago Sett Ott Nov Dic Gen Feb Mar Apr Mag Giu
2019/20202.149 0 0 0 0 0 422 324 491 309 208 335 60
2020/20212.724 210 225 201 299 96 324 99 247 188 398 125 312
2021/20221.363 56 132 79 58 73 55 61 88 75 59 304 323
2022/20233.372 346 445 162 338 269 639 478 169 354 11 115 46
2023/20241.163 48 145 204 67 74 173 32 241 20 64 41 54
2024/20255.775 267 834 446 1.137 2.408 683 0 0 0 0 0 0
Totale 22.660