STEFANI, MASSIMO
 Distribuzione geografica
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Continente #
NA - Nord America 14.316
EU - Europa 12.475
AS - Asia 5.497
SA - Sud America 769
Continente sconosciuto - Info sul continente non disponibili 200
AF - Africa 169
OC - Oceania 133
Totale 33.559
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Nazione #
US - Stati Uniti d'America 14.103
PL - Polonia 4.124
RU - Federazione Russa 2.772
IT - Italia 2.038
SG - Singapore 1.513
CN - Cina 1.159
HK - Hong Kong 925
SE - Svezia 861
IE - Irlanda 812
VN - Vietnam 741
BR - Brasile 634
DE - Germania 476
KR - Corea 455
UA - Ucraina 403
FI - Finlandia 284
FR - Francia 274
GB - Regno Unito 199
IN - India 190
AU - Australia 127
CA - Canada 117
TR - Turchia 85
ID - Indonesia 66
ES - Italia 64
BD - Bangladesh 56
JO - Giordania 53
NL - Olanda 52
JP - Giappone 50
AR - Argentina 47
CI - Costa d'Avorio 39
IQ - Iraq 38
MX - Messico 35
CH - Svizzera 34
ZA - Sudafrica 28
SC - Seychelles 21
PK - Pakistan 20
EC - Ecuador 19
NG - Nigeria 19
AE - Emirati Arabi Uniti 18
CO - Colombia 17
JM - Giamaica 16
MA - Marocco 15
TN - Tunisia 14
BE - Belgio 13
UZ - Uzbekistan 13
MY - Malesia 12
IL - Israele 11
PT - Portogallo 11
PY - Paraguay 11
VE - Venezuela 11
CL - Cile 10
EG - Egitto 10
KZ - Kazakistan 10
CR - Costa Rica 9
NP - Nepal 9
PH - Filippine 9
SA - Arabia Saudita 9
LT - Lituania 8
PE - Perù 8
RO - Romania 8
AZ - Azerbaigian 7
DO - Repubblica Dominicana 7
GT - Guatemala 7
TH - Thailandia 7
BG - Bulgaria 6
EU - Europa 6
GE - Georgia 6
IR - Iran 6
KE - Kenya 6
NZ - Nuova Zelanda 6
TW - Taiwan 6
BO - Bolivia 5
DK - Danimarca 5
HN - Honduras 5
UY - Uruguay 5
BH - Bahrain 4
CZ - Repubblica Ceca 4
ET - Etiopia 4
GR - Grecia 4
OM - Oman 4
SY - Repubblica araba siriana 4
TT - Trinidad e Tobago 4
AO - Angola 3
AT - Austria 3
DZ - Algeria 3
HU - Ungheria 3
KG - Kirghizistan 3
MU - Mauritius 3
PA - Panama 3
PR - Porto Rico 3
SV - El Salvador 3
XK - ???statistics.table.value.countryCode.XK??? 3
AL - Albania 2
BS - Bahamas 2
GA - Gabon 2
LK - Sri Lanka 2
LV - Lettonia 2
MD - Moldavia 2
MT - Malta 2
RS - Serbia 2
AM - Armenia 1
Totale 33.350
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Città #
Warsaw 4.123
Santa Clara 2.661
Ashburn 1.427
Fairfield 1.217
Singapore 1.046
Dublin 810
Chandler 787
Hong Kong 738
Jacksonville 635
Woodbridge 562
Cambridge 516
Houston 481
Seattle 467
Seoul 432
Milan 414
Wilmington 413
Beijing 346
San Jose 326
Buffalo 263
Florence 233
The Dalles 226
Princeton 212
Ho Chi Minh City 195
Ann Arbor 187
Rome 186
Los Angeles 178
Lauterbourg 169
Boston 164
Hefei 162
Altamura 161
Dallas 151
Council Bluffs 146
Dong Ket 145
Lawrence 138
Boardman 137
Hanoi 133
Melbourne 121
Mumbai 109
Moscow 108
Munich 95
Helsinki 77
San Diego 77
Medford 76
New York 70
Naples 63
Shanghai 63
Jakarta 53
São Paulo 52
Bremen 50
Turin 45
Izmir 44
Tokyo 41
Abidjan 39
Kent 39
Norwalk 39
Orem 38
West Jordan 36
Phoenix 35
Bologna 34
Clifton 34
Falls Church 34
Turku 33
Auburn Hills 28
Barcelona 28
Redondo Beach 28
Paris 26
Da Nang 24
Haiphong 24
Hillsboro 21
Toronto 21
Verona 21
Chicago 20
London 20
San Francisco 20
Bern 19
Frankfurt Am Main 19
Genoa 19
Montreal 19
Palermo 19
Rio de Janeiro 19
Abuja 18
Andover 18
Dearborn 18
Guangzhou 18
Salerno 18
Tianjin 18
Brooklyn 17
Chennai 17
Denver 17
Figino 17
Frankfurt am Main 17
Pune 17
Amsterdam 16
Brasília 16
Baghdad 15
Philadelphia 15
Bari 14
Belo Horizonte 14
Hải Dương 14
Padua 14
Totale 22.815
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Nome #
A causative link between the structure of aberrant protein oligomers and their toxicity 483
Oleuropein aglycone induces autophagy via the AMPK/mTOR signalling pathway: A mechanistic insight 402
Oleuropein aglycone protects against pyroglutamylated-3 amyloid-ß toxicity: biochemical, epigenetic and functional correlates 401
Oleuropein Aglycone: A Possible Drug against Degenerative Conditions. In Vivo Evidence of its Effectiveness against Alzheimer's Disease 375
The polyphenol oleuropein aglycone protects TgCRND8 mice against Aß plaque pathology 370
Biochemical and Electrophysiological Modification of Amyloid Transthyretin on Cardiomyocytes 361
Protein Folding and Aggregation into Amyloid: The Interference by Natural Phenolic Compounds 357
Uso della oleuropeina e suoi derivati nel trattamento del diabete mellito di tipo 2 e di patologie associate a fenomeni di aggregazione di proteine 347
Dephosphorylation of tyrosine phosphorylated synthetic peptides by rat liver phosphotyrosine protein phosphatase isoenzymes 346
Seladin-1/dhcr24 protects neuroblastoma cells against aβ toxicity by increasing membrane cholesterol content 338
Mild exposure of RIN-5F β-cells to human islet amyloid polypeptide aggregates upregulates antioxidant enzymes via NADPH oxidase-RAGE: An hormetic stimulus 331
proteomic analysis of cells exposed to prefibrillar aggregates of HypF-N 328
Binding affinity of amyloid oligomers to cellular membranes is a generic indicator of cellular dysfunction in protein misfolding diseases 326
Properties of N-terminus truncated and C-terminus mutated muscle acylphosphatases. 325
Molecular insights into cell toxicity of a novel familial amyloidogenic variant of β2-microglobulin 316
Oleuropein aglycone protects against MAO-A-induced autophagy impairment and cardiomyocyte death through activation of TFEB. 315
Soluble Oligomers Require a Ganglioside to Trigger Neuronal Calcium Overload 312
Employing AD animal models for translational research: focus on dietary components 312
Single molecule experiments emphasize GM1 as a key player of the different cytotoxicity of structurally distinct Aβ1-42 oligomers 300
Patterns of cell death triggered in two different cell lines by HypF-N prefibrillar aggregates. 299
Interaction of toxic and non-toxic HypF-N oligomers with lipid bilayers investigated at high resolution with atomic force microscopy 297
Toxic HypF-N oligomers selectively bind the plasma membrane to impair cell adhesion capability 282
The polyphenol oleuropein aglycone modulates the PARP1-SIRT1 interplay: an in vitro and in vivo study 263
Looking for residues involved in the muscle acylphosphatase catalytic mechanism and structural stabilization: role of Asn41, Ther42 and Thr46 261
Thermodynamics and kinetics of folding of common type acylphosphatase 259
Molecular links between aberrant protein oligomers and neurodegeneration in Alzheimer’s disease 257
The complete amino acid sequence of the low molecular weight cytosolic acid phosphatase 253
Oleuropein aglycone protects transgenic C. elegans strains expressing Abeta42 by reducing plauqe load and motor deficit 251
Single particle tracking to study the binding of protein misfolded oligomer to membrane ganglioside GM1 250
S-Homocysteinylation effects on transthyretin: worsening of cardiomyopathy onset 243
Nutraceutical properties of olive oli polyphenols. An itinerary from cultured cells through animal models to humans 241
Aspartic-129 is an essential residue in the catalytic mechanism of the low M(r) phosphotyrosine protein phosphatase 239
Olive oil polyphenols can be useful to prevent aging-associated neurodegeneration 238
A specific nanobody prevents amyloidogenesis of D76N β2-microglobulin in vitro and modifies its tissue distribution in vivo 231
Affinity chromatographic purification of horse muscle acylphosphatase: evidence of the existence of multiple molecular forms. 229
Crystal structure and anion binding in the prokaryotic hydrogenase maturation factor HypF acylphosphatase-like domain. 227
1,2,4-trihydroxynaphthalene-2-O-β-D-glucopyranoside delays amyloid-β42 aggregation and reduces amyloid cytotoxicity 225
Amyloid aggregation: role of biological membranes and the aggregate-membrane system 220
Acylphosphatase increases the rate of ethanol production from glucose in cell-free extract of Saccharomyces cerevisiae 219
Arg23 is involved in the catalytic site of muscle acylphosphatase. 215
1,2,4-trihydroxynapthalene-2-O-b-D-glucopyranoside: A new powerful antioxidant and inhibitor of Ab42 aggregation isolated from the leaves of Lawsonia inermis 213
Assessing the role of aromatic residues in the amyloid aggregation of human muscle acylphosphatase 210
A FTIR microspectroscopy study of the structural and biochemical perturbations induced by natively folded and aggregated transthyretin in HL-1 cardiomyocytes 206
A protective role for lipid raft cholesterol againsy amyloid-induced membrane damage in human neuroblastoma cells 205
Biological function in a non-native partially folded state of a protein. 204
Acylphosphatase from human skeletal muscle: purification, some properties and levels in normal and myopathic muscles 203
Differentiation increases the resistance of neuronal cells to amyloid toxicity 201
The (1-63) region of the p53 transactivation domain aggregates in vitro into cytotoxic amyloid assemblies 199
Healthy Effects of Plant Polyphenols: Molecular Mechanisms 197
Antisense peptides to 43-57 region of acylphosphatase and to 46-60 region of two isoenzymes of a low Mr PTPase do not interact with the corresponding proteins. 192
Expression, purification and preliminary crystal analysis of the human low Mr phosphotyrosine protein phosphatase isoform 1. 191
Neuronal differentiation of human mesenchymal stromal cells increases their resistance to Aβ42 aggregate toxicity. 191
Oleuropein aglycone counteracts Aβ42 toxicity in the rat brain 190
Oleuropein aglycone and polyphenols from olive mill waste water ameliorate cognitive deficits and neuropathology 187
Insights into the molecular basis of the differing susceptibility of varying cell types to the toxicity of amyloid aggregates 184
The polyphenol Oleuropein aglycone hinders the growth of toxic transthyretin amyloid assemblies 183
SASP-LIKE PHENOTYPE IN ALZHEIMER CELLULAR MODELS: MODULATION BY NATURAL PHENOLIC COMPOUNDS 183
CA2+-ATPASE FROM SARCOPLASMIC RETICULUM: ACYLPHOSPHATASE ACTIVITY 182
null 181
Membrane lipid composition and its physicochemical properties define cell vulnerability to aberrant protein oligomers 175
Oleuropein aglycon relieves memory impairments, induces brain autophagy and reduces Aß load in the TgCRND8 mouse model of Alzheimer’s Disease 175
C-terminal region contributes to muscle acylphosphatase three-dimensional structure stabilisation 174
Nutraceutical properties of olive oil polyphenols. An itinerary from cultured cells through animal models to humans 172
Effect of acylphosphates on Ca2+ uptake by sarcoplasmic reticulum vesicles. 172
Aggregation of the acylphosphatase from S. solfataricus. The folded and partially unfolded states can be both precursors for amyloid formation. 172
Expression and turnover of acylphosphatase (muscular isoenzyme) in L6 myoblasts during myogenesis. 172
Oleuropein aglycon prevents cytotoxic amyloid aggregation of human amylin 168
Comparison of the folding processes of distantly related proteins. Importance of hydrophobic content in folding. 167
The amyloid-cell membrane system. The interplay between the biophysical features of oligomers/fibrils and cell membrane defines amyloid toxicity 166
Olive polyphenols: new promising agents to combat aging-associated neurodegeneration 164
Autophagy-related proteins: potential diagnostic and prognostic biomarkers of aging-related diseases. 163
Oleuropein aglycone and hydroxytyrosol interfere differently with toxic Aβ 1-42 aggregation 163
Guinea pig acylphosphatase: the amino acid sequence 162
Differing molecular mechanisms appear to underlie early toxicity of pre-fibrillar HypF-N aggregates to different cell types 162
Different ataxin-3 amyloid aggregates induce intracellular Ca2+ deregulation by different mechanisms in cerebellar granule cells 162
Purification and characterization of rabbit muscle acylphosphatase in the thiol (-SH) form. 161
Nonspecific interaction of prefibrillar amyloid aggregates with glutamatergic receptors results in Ca2+ increase in primary neuronal cells 159
Monitoring the process of HypF fibrillization and liposome permeabilization by protofibrils. 159
Abeta(1-42) aggregates into non-toxic amyloid assemblies in the presence of the natural polyphenol oleuropein aglycon 156
Autophagy Dysregulation in Alzheimer’s Disease: Plant Polyphenols as A Possible Preventive and Therapeutic Treatment. 156
Beta2-microglobulin is potentially neurotoxic, but the blood brain barrier is likely to protect the brain from its toxicity 156
Rabbit skeletal muscle acylphosphatase: the amino acid sequence of form Ra1. 155
LYSOZYME INTERACTION WITH NEGATIVELY CHARGED LIPID BILAYERS: PROTEIN AGGREGATION AND MEMBRANE FUSION 155
CRYSTALLISATION OF A LOW MOLECULAR WEIGHT PHOSPHOTYROSINE PROTEIN PHOSPHATASE FROM BOVINE LIVER. 155
Investigation of the effects of copper ions on protein aggregation using a model system. 154
null 154
Inherent toxicity of aggregates implies a common mechanism for protein misfolding diseases 153
Replicating neuroblastoma cells in different cell cycle phases display different vulnerability to amyloid toxicity 153
Protein misfolding and aggregation: new examples in medicine and biology of the dark side of the protein world 153
Amyloid polymorphisms: structural basis and significance in biology and molecular medicine 153
Oleuropein aglycone induces autophagy in neonatal rat cardiomyocytes. Evidences of beneficial effects in an “in vitro” model of cardiomyopathy characterized by autophagy. 153
The Amphipathic GM1 Molecule Stabilizes Amyloid Aggregates, Preventing their Cytotoxicity 153
Preparation and some properties of a dimeric form (S-S) of horse muscle acylphosphatase 151
Oleuropein aglycone stabilizes the monomeric α-synuclein and favours the growth of non-toxic aggregates 151
The yeast prion Ure2p native-like assemblies are toxic to mammalian cells regardless to their aggregation state 149
Oleuropein aglycone induces autophagy in neuroblastoma cells: a mechanicistic insight. 149
Beneficial properties of natural phenols. Highlight on protection against pathological conditions associated with amyloid aggregation 148
Olive Polyphenols: Antioxidant and Anti-Inflammatory Properties 148
Horse brain acylphosphatase: purification and characterization 147
Il nuovo medicina e biologia 147
Totale 22.063
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Categoria #
all - tutte 85.575
article - articoli 0
book - libri 0
conference - conferenze 0
curatela - curatele 0
other - altro 0
patent - brevetti 0
selected - selezionate 0
volume - volumi 0
Totale 85.575
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Totale Lug Ago Sett Ott Nov Dic Gen Feb Mar Apr Mag Giu
2021/20221.307 0 132 79 58 73 55 61 88 75 59 304 323
2022/20233.372 346 445 162 338 269 639 478 169 354 11 115 46
2023/20241.163 48 145 204 67 74 173 32 241 20 64 41 54
2024/20257.548 267 834 446 1.137 2.408 882 130 444 354 183 256 207
2025/20268.758 898 1.202 682 615 871 402 1.109 436 583 483 198 1.279
2026/2027368 324 44 0 0 0 0 0 0 0 0 0 0
Totale 33.559